Artificial Cells  Cell Engineering and Therapy Book

Artificial Cells Cell Engineering and Therapy


  • Author : S Prakash
  • Publisher : Elsevier
  • Release Date : 2007-05-31
  • Genre: Science
  • Pages : 544
  • ISBN 10 : 9781845693077

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Artificial Cells Cell Engineering and Therapy Excerpt :

Artificial cells, cell engineering and therapy are emerging technologies which will make a significant impact on the future of medicine and healthcare. However, research within the field is vast. This unique book provides a comprehensive study of the most recent advances in the field and its practical applications. The first part of the book offers the reader an introduction to the basics of artificial cell technology with chapters on its origins, design, current status within medicine and future prospects. Part two covers apoptosis, the use of bone marrow stromal cells in myocardial regeneration together with signalling and tissue engineering. Part three discusses artificial cells for therapy, procedures for various clinical conditions and the current status of the discipline within the field. The book concludes with a final section on the role of artificial cells in medicine with particular focus on the use of artificial cells as blood substitutes and their potential use in myocardial regeneration, drug delivery and in treating kidney and bowel diseases, diabetes and cancer. Artificial cells, cell engineering and therapy is a valuable reference for researchers, students and practitioners within the field. Introduces the basics of artificial cell technology Provides a comprehensive study of the most recent advances in artificial cells, cell engineering and cell therapy Discusses the design, engineering and uses of artificial cells

Artificial Cells Book
Score: 2
From 2 Ratings

Artificial Cells


  • Author : Thomas Ming Swi Chang
  • Publisher : World Scientific
  • Release Date : 2007
  • Genre: Science
  • Pages : 455
  • ISBN 10 : 9789812705761

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Artificial Cells Excerpt :

This is the first book that provides a comprehensive review of the entire area of artificial cells. The author, a pioneer of the field, invented the first artificial cells some 50 years ago and has continued to carry out active research in this field. Since then, there have been explosive research activities around the world on artificial cells, especially in fields related to biotechnology, nanomedicine, cell therapy, blood substitutes, drug delivery and others. However, instead of the term ?artificial cells,? many authors use other terminologies such as blood substitutes, bioencapsulation, liposomes, nanoparticles and so on. Furthermore, papers in this highly interdisciplinary area are published in numerous journals specializing in chemistry, medicine, surgery, bioengineering and others, while books in this area are mostly multi-authored, describing very specific and narrow areas. As a result, any meaningful literature search for a complete idea of the present status of the whole field of artificial cells is impossible. This monograph is written to fill this gap by including all those areas in artificial cells that are disguised under different terminologies. Each chapter begins with a detailed overview, followed by detailed examples of the author's own research and a full description of his methods and procedures. Readers interested in a detailed overview of the whole area can read from cover to cover, omitting the methods section at the end of each chapter; while those entering this area of research will find the detailed methods and procedures very useful.

Tissue Engineering Using Ceramics and Polymers Book

Tissue Engineering Using Ceramics and Polymers


  • Author : Aldo R. Boccaccini
  • Publisher : Elsevier
  • Release Date : 2007-10-31
  • Genre: Science
  • Pages : 624
  • ISBN 10 : 9781845693817

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Tissue Engineering Using Ceramics and Polymers Excerpt :

Technology and research in the field of tissue engineering has drastically increased within the last few years to the extent that almost every tissue and organ of the human body could potentially be regenerated. With its distinguished editors and international team of contributors, Tissue Engineering using Ceramics and Polymers reviews the latest research and advances in this thriving area and how they can be used to develop treatments for disease states. Part one discusses general issues such as ceramic and polymeric biomaterials, scaffolds, transplantation of engineered cells, surface modification and drug delivery. Later chapters review characterisation using x-ray photoelectron spectroscopy and secondary ion mass spectrometry as well as environmental scanning electron microscopy and Raman micro-spectroscopy. Chapters in part two analyse bone regeneration and specific types of tissue engineering and repair such as cardiac, intervertebral disc, skin, kidney and bladder tissue. The book concludes with the coverage of themes such as nerve bioengineering and the micromechanics of hydroxyapatite-based biomaterials and tissue scaffolds. Tissue Engineering using Ceramics and Polymers is an innovative reference for professionals and academics involved in the field of tissue engineering. An innovative and up-to-date reference for professionals and academics Environmental scanning electron microscopy is discussed Analyses bone regeneration and specific types of tisue engineering

Stem Cell Bioengineering and Tissue Engineering Microenvironment Book

Stem Cell Bioengineering and Tissue Engineering Microenvironment


  • Author : Satya Prakash
  • Publisher : World Scientific
  • Release Date : 2011
  • Genre: Bioengineering
  • Pages : 542
  • ISBN 10 : 9789812837899

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Stem Cell Bioengineering and Tissue Engineering Microenvironment Excerpt :

This is a comprehensive review of the current state of stem cell bioengineering from authorities in the field. The first part of the book includes the basic research work on stem cells and bioengineering carried out by various laboratories. The second part consists of a review of the current development of various microcapsules in stem cell therapy. The last part will summarize the overall clinical trials on stem cell therapy and myocardial regeneration as well as the most updated personal experience recently completed by well-known experts in this field.

Artificial Cells Book

Artificial Cells


  • Author : Thomas Ming Swi Chang
  • Publisher : World Scientific
  • Release Date : 2007
  • Genre: Medical
  • Pages : 482
  • ISBN 10 : 9789812770370

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Artificial Cells Excerpt :

50th anniversary of artificial cells -- Basic principles -- Oxygen carriers based on nanobiotechnology -- A nanobiotechnologic therapeutic that transports oxygen and remove oxygen radicals: for stroke, hemorrhagic shock and related conditions -- Nanotechnology-based artificial red blood cells (RBC's) -- Use of enzyme artificial cells for genetic enzyme defects that increase systemic substrates to toxic levels -- Enzyme artificial cells in substrate-dependent tumors and activation of prodrug -- Artificial cells for cell encapsulation -- Artificial cells containing hepatocytes and/or stem cells in regenerative medicine -- Hemoperfusion in poisoning, kidney failure, liver failure, and immunology -- Perspectives on the future of artificial cells as suggested by past research.

Standardisation in Cell and Tissue Engineering Book

Standardisation in Cell and Tissue Engineering


  • Author : V Salih
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Genre: Science
  • Pages : 276
  • ISBN 10 : 9780857098726

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Standardisation in Cell and Tissue Engineering Excerpt :

The increased use of biodegradable synthetic or natural scaffolds combined with cells and/or biological molecules, in order to create functional replacement tissue in a damaged tissue site, has led to the need for the development of ‘best practice’ methods in the area of tissue engineering to help ensure the creation of safe, high quality products. Standardisation in cell and tissue engineering introduces concepts and current practice in the field of cell and tissue engineering to a wide audience and aims to provide awareness of the importance of standardisation in this area while suggesting directions for further investigation. Part one provides an overview of methods for cell and tissue engineering and includes chapters on the fundamentals of cell and matrix biology for tissue engineering, 3D collagen biomatrix development, and control and vascularisation of tissue-engineered constructs. Part two begins with a chapter exploring the methods and protocols of standardisation in cell and tissue engineering before moving on to highlight issues of quality control in cell and tissue engineering, standardised chemical analysis and testing of biomaterials and principles of good laboratory practice (GLP) for in vitro cell culture applications. Standardisation in cell and tissue engineering is a standard reference for leading research groups, government agencies, regulatory bodies, and researchers and technicians at all levels across the whole range of disciplines using cell culture within the pharmaceutical, biotechnology and biomedical industries. Introduces concepts and current practice in the field of cell and tissue engineering Highlights the importance of standardisation in cell and tissue engineering and suggests directions for further investigation Explores methods and protocols of standardisation in cell and tissue engineering and issues of quality control in cell and tissue engineering

Nanomaterials in Tissue Engineering Book

Nanomaterials in Tissue Engineering


  • Author : A K Gaharwar
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Genre: Technology & Engineering
  • Pages : 468
  • ISBN 10 : 9780857097231

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Nanomaterials in Tissue Engineering Excerpt :

Nanomaterial technologies can be used to fabricate high-performance biomaterials with tailored physical, chemical, and biological properties. They are therefore an area of interest for emerging biomedical technologies such as scaffolding, tissue regeneration, and controlled drug delivery. Nanomaterials in tissue engineering explores the fabrication of a variety of nanomaterials and the use of these materials across a range of tissue engineering applications. Part one focuses on the fabrication of nanomaterials for tissue engineering applications and includes chapters on engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials. Part two goes on to highlight the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering. Finally, the use of nanomaterials in hard tissue engineering applications, including bone, dental and craniofacial tissue engineering is discussed in part three. Nanomaterials in tissue engineering is a standard reference for researchers and tissue engineers with an interest in nanomaterials, laboratories investigating biomaterials, and academics interested in materials science, chemical engineering, biomedical engineering and biological sciences. Explores the fabrication of a variety of nanomaterials and their use across a range of tissue engineering applications Examines engineering nanoporous biomaterials, layer-by-layer self-assembly techniques for nanostructured devices, and the synthesis of carbon based nanomaterials Highlights the application of nanomaterials in soft tissue engineering and includes chapters on cardiac, neural, and cartilage tissue engineering

Biomedical Foams for Tissue Engineering Applications Book

Biomedical Foams for Tissue Engineering Applications


  • Author : Paulo Netti
  • Publisher : Elsevier
  • Release Date : 2014-02-28
  • Genre: Science
  • Pages : 446
  • ISBN 10 : 9780857097033

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Biomedical Foams for Tissue Engineering Applications Excerpt :

Biomedical foams are a new class of materials, which are increasingly being used for tissue engineering applications. Biomedical Foams for Tissue Engineering Applications provides a comprehensive review of this new class of materials, whose structure can be engineered to meet the requirements of nutrient trafficking and cell and tissue invasion, and to tune the degradation rate and mechanical stability on the specific tissue to be repaired. Part one explores the fundamentals, properties, and modification of biomedical foams, including the optimal design and manufacture of biomedical foam pore structure for tissue engineering applications, biodegradable biomedical foam scaffolds, tailoring the pore structure of foam scaffolds for nerve regeneration, and tailoring properties of polymeric biomedical foams. Chapters in part two focus on tissue engineering applications of biomedical foams, including the use of bioactive glass foams for tissue engineering applications, bioactive glass and glass-ceramic foam scaffolds for bone tissue restoration, composite biomedical foams for engineering bone tissue, injectable biomedical foams for bone regeneration, polylactic acid (PLA) biomedical foams for tissue engineering, porous hydrogel biomedical foam scaffolds for tissue repair, and titanium biomedical foams for osseointegration. Biomedical Foams for Tissue Engineering Applications is a technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine. Explores the fundamentals, properties, and modification of biomedical foams Includes intense focus on tissue engineering applications of biomedical foams A technical resource for researchers and developers in the field of biomaterials, and academics and students of biomedical engineering and regenerative medicine

Silk Biomaterials for Tissue Engineering and Regenerative Medicine Book

Silk Biomaterials for Tissue Engineering and Regenerative Medicine


  • Author : Subhas Kundu
  • Publisher : Elsevier
  • Release Date : 2014-03-24
  • Genre: Medical
  • Pages : 582
  • ISBN 10 : 9780857097064

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Silk Biomaterials for Tissue Engineering and Regenerative Medicine Excerpt :

Silk is increasingly being used as a biomaterial for tissue engineering applications, as well as sutures, due to its unique mechanical and chemical properties. Silk Biomaterials for Tissue Engineering and Regenerative Medicine discusses the properties of silk that make it useful for medical purposes and its applications in this area. Part one introduces silk biomaterials, discussing their fundamentals and how they are processed, and considering different types of silk biomaterials. Part two focuses on the properties and behavior of silk biomaterials and the implications of this for their applications in biomedicine. These chapters focus on topics including biodegradation, bio-response to silk sericin, and capillary growth behavior in porous silk films. Finally, part three discusses the applications of silk biomaterials for tissue engineering, regenerative medicine, and biomedicine, with chapters on the use of silk biomaterials for vertebral, dental, dermal, and cardiac tissue engineering. Silk Biomaterials for Tissue Engineering and Regenerative Medicine is an important resource for materials and tissue engineering scientists, R&D departments in industry and academia, and academics with an interest in the fields of biomaterials and tissue engineering. Discusses the properties and applications of silk for medical purposes Considers pharmaceutical and cosmeceutical applications

Selected Topics in Nanomedicine Book

Selected Topics in Nanomedicine


  • Author : Thomas Ming Swi Chang
  • Publisher : World Scientific
  • Release Date : 2013-09-16
  • Genre: Medical
  • Pages : 600
  • ISBN 10 : 9789814472876

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Selected Topics in Nanomedicine Excerpt :

Nanomedicine consists of the use of nanotechnology and nanobiotechnology in medicine. There have been extensive developments in the area of nanomedicine. The scope of this book is first to discuss the origin of nanomedicine. Following this, instead of a general overview of the whole area, 24 chapters on selected topics of important areas are described in detail. Authors are selected from around the world to give a representative and international view of the activities in the area of nanomedicine. Contents:Artificial Cells: The Beginning of Nanomedicine (Thomas Ming Swi Chang)The Clinical Development of Hemopure®: A Selective Commentary (A Gerson Greenburg)Glutaraldehyde Polymerized Porcine Hemoglobin: Preparation, Safety Evaluation and Pharmacodynamics Study (Chao Chen, Hongli Zhu and Kunping Yan)Evidence Regarding Some Pharmacologic Characteristics of Hemoglobin-Based Oxygen Carriers (Enrico Bucci)EAF PEG Hemoglobins: Novel Class of Nonhypertensive Resuscitation Fluids: Simplicity and Advantages of Extension Arm Chemistry for PEGylation (Seetharama A Acharya, Amy G Tsai and Marcos Intaglietta)Biocompatibility of a Highly Concentrated Fluid of Hemoglobin-Vesicles as a Transfusion Alternative (Hiromi Sakai)Molecular Basis of Haptoglobin and Hemoglobin Complex Formation and Protection against Oxidative Stress and Damage (Yiping Jia and Abdu I Alayash)Polynitroxylated Hemoglobin as a Multifunctional Therapeutic for Critical Care and Transfusion Medicine (Li Ma and Carleton Jen Chang Hsia)Surface-Mediated Drug Delivery (Benjamin M Wohl, Betina Fejerskov, Siow-Feng Chong and Alexander N Zelikin)Use of Tunable Pores for Accurate Characterization of Micro- and Nanoparticle Systems in Nanomedicine (James Eldridge, Aaron H Colby, Geoff R Willmott, Sam Yu and Mark W Grinstaff)Microfluidic Probes to Process Surfaces, Cells, and Tissues (Mohammad A Qasaimeh, Sebastien G Ricoult and David Juncker)Subcompartmentalized Systems Towards Therapeutic Cell Mimics (Leticia Hosta-Rigau

Cell Therapy  Stem Cells and Brain Repair Book

Cell Therapy Stem Cells and Brain Repair


  • Author : Cyndy D. Davis
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-09
  • Genre: Medical
  • Pages : 392
  • ISBN 10 : 9781597451475

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Cell Therapy Stem Cells and Brain Repair Excerpt :

As our world continues to evolve, the field of regenerative medicine f- lows suit. Although many modern day therapies focus on synthetic and na- ral medicinal treatments for brain repair, many of these treatments and prescriptions lack adequate results or only have the ability to slow the p- gression of neurological disease or injury. Cell therapy, however, remains the most compelling treatment for neurodegenerative diseases, disorders, and injuries, including Parkinson’s disease, Huntington’s disease, traumatic brain injury, and stroke, which is expanded upon in more detail in Chapter 1 by Snyder and colleagues. Cell therapy is also unique in that it is the only therapeutic strategy that strives to replace lost, damaged, or dysfunctional cells with healthy ones. This repair and replacement may be due to an administration of exogenous cells itself or the activation of the body’s own endogenous reparative cells by a trophic, immune, or inflammatory response to cell transplantation. However, the precise mechanism of how cell therapy works remains elusive and is c- tinuing to be investigated in terms of molecular and cellular responses, in particular. Moreover, Chapter 11 by Emerich and associates, discusses some of the possibilities of cell immunoisolation and the potential for treating central nervous system diseases.

Principles of Regenerative Medicine Book
Score: 5
From 1 Ratings

Principles of Regenerative Medicine


  • Author : Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2010-12-16
  • Genre: Science
  • Pages : 1202
  • ISBN 10 : 0123814235

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Principles of Regenerative Medicine Excerpt :

Virtually any disease that results from malfunctioning, damaged, or failing tissues may be potentially cured through regenerative medicine therapies, by either regenerating the damaged tissues in vivo, or by growing the tissues and organs in vitro and implanting them into the patient. Principles of Regenerative Medicine discusses the latest advances in technology and medicine for replacing tissues and organs damaged by disease and of developing therapies for previously untreatable conditions, such as diabetes, heart disease, liver disease, and renal failure. Key for all researchers and instituions in Stem Cell Biology, Bioengineering, and Developmental Biology The first of its kind to offer an advanced understanding of the latest technologies in regenerative medicine New discoveries from leading researchers on restoration of diseased tissues and organs

Molecular Communication Book

Molecular Communication


  • Author : Tadashi Nakano
  • Publisher : Cambridge University Press
  • Release Date : 2013-09-12
  • Genre: Computers
  • Pages : 192
  • ISBN 10 : 9781107023086

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Molecular Communication Excerpt :

A comprehensive guide written by pioneers in the field, providing a detailed introduction to the state of the art in molecular communication.

Cell Free Synthetic Biology Book

Cell Free Synthetic Biology


  • Author : Jian Li
  • Publisher : Frontiers Media SA
  • Release Date : 2022-01-13
  • Genre: Science
  • Pages : null
  • ISBN 10 : 9782889740802

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Cell Free Synthetic Biology Excerpt :

Handbook of Oxidative Stress in Cancer  Therapeutic Aspects Book

Handbook of Oxidative Stress in Cancer Therapeutic Aspects


  • Author : Sajal Chakraborti
  • Publisher : Springer Nature
  • Release Date : 2022-09-28
  • Genre: Medical
  • Pages : 4076
  • ISBN 10 : 9789811654220

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Handbook of Oxidative Stress in Cancer Therapeutic Aspects Excerpt :

This reference book, which is the second volume of Targeting Oxidative Stress in Cancer, explores oxidative stress as the potential therapeutic target for cancer therapy. The initial chapters discuss the molecular mechanisms of oxidative stress and its effects on different signaling pathways. Subsequently, the sections examine the impact of redox signaling on tumor cell proliferation and consider the therapeutic potential of dietary phytochemicals and nutraceuticals in reactive oxygen species (ROS)-induced cancer. In turn, it examines the evidence supporting the use of Vitamin C in cancer management, before presenting various synthetic and natural compounds that have therapeutic implications for oxidative stress-induced cancer. It also explores the correlation between non-coding RNA and oxidative stress. Furthermore, the book summarizes the role of stem cells in ROS-induced cancer therapy and reviews the therapeutic applications of nanoparticles to alter redox haemostasis in cancer cells. Lastly, it explores heat-shock proteins, ubiquitin ligases, and probiotics as potential therapeutic agents in ROS-mediated cancer. This book is a useful resource for basic and translational scientists as well as clinicians interested in the field of oxidative stress and cancer therapy. ​