Atlas of Early Zebrafish Brain Development Book

Atlas of Early Zebrafish Brain Development


  • Author : Dr. Thomas Mueller
  • Publisher : Academic Press
  • Release Date : 2015-11-18
  • Genre: Science
  • Pages : 258
  • ISBN 10 : 9780124172869

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Atlas of Early Zebrafish Brain Development Excerpt :

Atlas of Early Zebrafish Brain Development: A Tool for Molecular Neurogenetics, Second Edition, remains the only neuroanatomical expression atlas of important genetic and immunohistochemical markers of this vertebrate model system. It represents a key reference and interpretation matrix for analyzing expression domains of genes involved in Zebrafish brain development and neurogenesis, and serves as a continuing milestone in this research area. This updated volume provides in-situ hybridized and immunostained preparations of complete series of brain sections, revealing markers of the fundamental stages in the life history of neuronal cells in very high quality preparations and photographic plates. Specific additions to this edition include documentation on the distribution of neurons expressing GABA, dopamine and serotonin, material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon, new theories on the early organization of the telencephalon and thalamus, and integration of a comparative perspective on the mid- and hindbrain. Documentation on the distribution of neurons expressing GABA, dopamine and serotonin Material on the basal ganglia, hypothalamus, and the caudal, segmented part of the diencephalon New theories about the early organization of the telencephalon and thalamus Integration of a comparative perspective on the mid- and hindbrain

Atlas of Early Zebrafish Brain Development Book

Atlas of Early Zebrafish Brain Development


  • Author : Thomas Mueller
  • Publisher : Gulf Professional Publishing
  • Release Date : 2005-08-08
  • Genre: Medical
  • Pages : 204
  • ISBN 10 : 0444517383

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Atlas of Early Zebrafish Brain Development Excerpt :

The Atlas of Early Zebrafish Brain Development is the first neuroanatomical expression atlas of important genetic and immunohistochemical markers of a vertebrate model system. In-situ hybridized and immunostained preparations of complete series of brain sections reveal markers of the fundamental stages in the life history of neuronal cells (proliferation/determination, migration and neuronal differentiation) in very high quality preparations and photographic plates. Early brain organization is vividly demonstrated and local variations in brain development are shown in a holistic view. This book represents a key reference and interpretation matrix to analyze expression domains of genes involved in Zebrafish brain development and neurogenesis and thus represents a milestone in this research area. There is simply no alternative source for combined neuroanatomical and gene expression data in the Zebrafish at this level of detail. The book introduces the reader to the field and shows principles of vertebrate brain development and neurogenesis. It will also be of great value to investigators of other model organisms such as frog, chick and mouse.

Neuroanatomy of the Zebrafish Brain Book

Neuroanatomy of the Zebrafish Brain


  • Author : Mario F. Wulliman
  • Publisher : Birkhäuser
  • Release Date : 1997-03-14
  • Genre: Science
  • Pages : 156
  • ISBN 10 : 3034898525

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Neuroanatomy of the Zebrafish Brain Excerpt :

gene-expression patterns in the zebrafish correspond well The zebrafish belongs to the teleostean family of with the neuromeric model of Puelles and Rubenstein cyprinids (minnows), which includes other neurobiologi­ (1993) is very encouraging for further research in this cally well investigated species such as goldfish (Carassius model system, which holds the promise of revealing fun­ auratus) and carp (e. g. Cyprinus carpio). damental neurogenetic patterns and mechanisms in ver­ In a recent taxonomic revision (Barman, 1991), all spe­ tebrates. cies of the genus Brachydanio were reassigned to the genus Danio. Thus, the current species designation of the zebrafish is Danio (formerly Brachydanio) rerio (Hamil­ ton-Buchanan, 1822). As a cyprinid, the zebrafish belongs Generation of zebrafish mutants via saturation mutagenesis to the large group of ostariophysan teleosts (6000 species, The goal of saturation mutagenesis is to identify most - if Lauder and Liem, 1983). Most ostariophysans are charac­ not all- genes affecting early animal development and to terized by a sophisticated apparatus - the Weberian ossi­ understand their hierarchical, regulative role during de­ des - to transmit sound from the swim bladder to the velopment (for reviews, see: Mullins and Ntisslein-Vol­ inner ear. The ostariophysans belong to the most derived hard, 1993; Solnica-Krezel et aI. , 1994). This approach has group of teleosts, the euteleosts (17000 species), which recently been applied to the zebrafish system, and the re­ have three more basic teleostean outgroups, the oste­ sults are impressive.

Atlas of Zebrafish Development Book

Atlas of Zebrafish Development


  • Author : Robert Bryson-Richardson
  • Publisher : Academic Press
  • Release Date : 2011-09-21
  • Genre: Science
  • Pages : 240
  • ISBN 10 : 9780123740168

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Atlas of Zebrafish Development Excerpt :

Zebrafish are widely considered an excellent model system for vertebrate development. The embryo is transparent, thereby enabling visualization and use of labelling and transgenic approaches. Moreover, because of the ease of inducing new mutations in zebrafish and similarity with the human genome, this organism may be used effectively for disease studies. For example, mutant zebrafish are being utilized for testing drugs that will combat a range of human diseases, from Alzheimer's and cancer to kidney failure and congenital heart disease. For the first time, this atlas provides the research community with a complete reference for zebrafish anatomy spanning the early embryo all the way to adulthood. The authors employ the technique of optical projection tomography (OPT), and offer a series of sections in multiple planes from each sample. The contents are organized by developmental stages, with over 200 images that contain annotations describing anatomical structures relevant to development. In addition, chapters feature explanatory text that highlights major developments in the zebrafish during each stage. Provides the first comprehensive anatomical resource that covers all regions of zebrafish anatomy from the larval period to adulthood The over 200 images include explanatory notes Each chapter contains a concise description of key anatomical features that factor in zebrafish development Despite many years of use as a model system, until now there has never been a guide to zebrafish at the larval stage The book's website contains a database of over 10k sections from different regions as well as 3D images that are interactive

Behavioral and Neural Genetics of Zebrafish Book

Behavioral and Neural Genetics of Zebrafish


  • Author : Robert T. Gerlai
  • Publisher : Academic Press
  • Release Date : 2020-04-03
  • Genre: Medical
  • Pages : 614
  • ISBN 10 : 9780128175293

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Behavioral and Neural Genetics of Zebrafish Excerpt :

Behavioral and Neural Genetics of Zebrafish assembles the state-of-the-art methodologies and current concepts pertinent to their neurobehavioral genetics. Discussing their natural behavior, motor function, learning and memory, this book focuses on the fry and adult zebrafish, featuring a comprehensive account of modern genetic and neural methods adapted to, or specifically developed for, Danio rerio. Numerous examples of how these behavioral methods may be utilized for disease models using the zebrafish are presented, as is a section on bioinformatics and "big-data" related questions. Provides the most comprehensive snapshot of the fast-evolving zebrafish neurobehavior genetics field Describes behavioral, genetic and neural methods and concepts for use in adult and larval zebrafish Features examples of zebrafish models of human central nervous system disorders Discusses bioinformatics questions pertinent to zebrafish neurobehavioral genetics

Development and Engineering of Dopamine Neurons Book

Development and Engineering of Dopamine Neurons


  • Author : Jeroen Pasterkamp
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-12-16
  • Genre: Medical
  • Pages : 127
  • ISBN 10 : 9781441903228

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Development and Engineering of Dopamine Neurons Excerpt :

Theneurotransmitter dopamine has just celebrated its 50thbirthday. The discovery of dopamine as a neuronal entity in the late 1950s and the notion that it serves in neurotransmission has been a milestone in the field of neuroscience research. This milestone marked the beginning of an era that explored the brain as an integrated collection of neuronal systems that one could distinguish on basis of neurotransm- ter identities, and importantly, in which one started to be able to pinpoint the seat of brain disease. The mesodiencephalic dopaminergic (mdDA) system, previously designated as midbraindopaminergic system, has received much attention since its discovery. The initial identification of dopamine as a neurotransmitter in the central nervous system (CNS) and its relevance to psychiatric and neurological disorders have stimulated a plethora of neurochemical, pharmacological and genetic studies into the function of dopamine neurons and theirprojections. In the last decade, studies on gene expression and development have further increased the knowledge of this neuronal population and have unmasked a new level of complexity. The start of the molecular dissection of the mdDA system has been marked by the cloning and characterization ofNurrl and Pitx3. These transcription factors were shown to have a critical function during mdDA development. These initial studies have been followed by the identification of many other proteins, which have a crucial function in the creation of a dopamine neuron permissive region, induction of precursors, induction of terminaldifferent- tion and finally maintenance of the mdDA neuronal pool.

The world according to zebrafish  How neural circuits generate behaviour Book

The world according to zebrafish How neural circuits generate behaviour


  • Author : Gonzalo G. De Polavieja
  • Publisher : Frontiers E-books
  • Release Date : 2014-11-07
  • Genre: Electronic book
  • Pages : 368
  • ISBN 10 : 9782889193288

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The world according to zebrafish How neural circuits generate behaviour Excerpt :

Understanding how the brain functions is one of the most ambitious current scientific goals. This challenge will only be accomplish by a multidisciplinary approach involving genetics, molecular biology, optics, ethology, neurobiology and mathematics and using tractable model systems. The zebrafish larva is a transparent genetically tractable small vertebrate, ideal for the combination state-of-the- art imaging techniques (e.g. two-photon scanning microscopy, single-plane illumination microscopy, spatial light modulator microscopy and lightfield microscopy), bioluminiscence and optogenetics to monitor and manipulate neuronal activity from single specific neurons up to the entire brain, in an intact behaving organism. Furthermore, the zebrafish model offers large and increasing collection of mutant and transgenic lines modelling human brain diseases. With these advantages in hand, the zebrafish larva became in the recent years, a novel animal model to study neuronal circuits and behaviour, taking us closer than ever before to understand how the brain controls behaviour.

Evolution of Nervous Systems Book

Evolution of Nervous Systems


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2016-11-23
  • Genre: Science
  • Pages : 2007
  • ISBN 10 : 9780128040966

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Evolution of Nervous Systems Excerpt :

Evolution of Nervous Systems, Second Edition is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike. Presents a broad range of topics, ranging from genetic control of development in invertebrates, to human cognition, offering a one-stop resource for the evolution of nervous systems throughout the animal kingdom Incorporates the expertise of over 100 outstanding investigators who provide their conclusions in the context of the la

The Superior Colliculus Tectum  Cell Types  Circuits  Computations  Behaviors Book

The Superior Colliculus Tectum Cell Types Circuits Computations Behaviors


  • Author : Karl Farrow
  • Publisher : Frontiers Media SA
  • Release Date : 2019-08-16
  • Genre: Uncategoriezed
  • Pages : 137
  • ISBN 10 : 9782889459711

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The Superior Colliculus Tectum Cell Types Circuits Computations Behaviors Excerpt :

This eBook is a collection of articles from a Frontiers Research Topic. Frontiers Research Topics are very popular trademarks of the Frontiers Journals Series: they are collections of at least ten articles, all centered on a particular subject. With their unique mix of varied contributions from Original Research to Review Articles, Frontiers Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author by contacting the Frontiers Editorial Office: frontiersin.org/about/contact.

Adaptive Function and Brain Evolution Book

Adaptive Function and Brain Evolution


  • Author : Agustín González
  • Publisher : Frontiers E-books
  • Release Date : 2014-10-27
  • Genre: Brain
  • Pages : 267
  • ISBN 10 : 9782889193066

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Adaptive Function and Brain Evolution Excerpt :

The brain of each animal shows specific traits that reflect its phylogenetic history and its particular lifestyle. Therefore, comparing brains is not just a mere intellectual exercise, but it helps understanding how the brain allows adaptive behavioural strategies to face an ever-changing world and how this complex organ has evolved during phylogeny, giving rise to complex mental processes in humans and other animals. These questions attracted scientists since the times of Santiago Ramon y Cajal one of the founders of comparative neurobiology. In the last decade, this discipline has undergone a true revolution due to the analysis of expression patterns of morphogenetic genes in embryos of different animals. The papers of this e-book are good examples of modern comparative neurobiology, which mainly focuses on the following four Grand Questions: a) How are different brains built during ontogeny? b) What is the anatomical organization of mature brains and how can they be compared? c) How do brains work to accomplish their function of ensuring survival and, ultimately, reproductive success? d) How have brains evolved during phylogeny? The title of this e-book, Adaptive Function and Brain Evolution, stresses the importance of comparative studies to understand brain function and, the reverse, of considering brain function to properly understand brain evolution. These issues should be taken into account when using animals in the research of mental function and dysfunction, and are fundamental to understand the origins of the human mind.

Flow Sensing in Air and Water Book

Flow Sensing in Air and Water


  • Author : Horst Bleckmann
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-01-22
  • Genre: Science
  • Pages : 562
  • ISBN 10 : 9783642414466

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Flow Sensing in Air and Water Excerpt :

In this book, leading scientists in the fields of sensory biology, neuroscience, physics and engineering explore the basic operational principles and behavioral uses of flow sensing in animals and how they might be applied to engineering applications such as autonomous control of underwater or aerial vehicles. Although humans possess no flow-sensing abilities, countless aquatic (e.g. fish, cephalopods and seals), terrestrial (e.g. crickets and spiders) and aerial (e.g. bats) animals have flow sensing abilities that underlie remarkable behavioral feats. These include the ability to follow silent hydrodynamic trails long after the trailblazer has left the scene, to form hydrodynamic images of their environment in total darkness, and to swim or fly efficiently and effortlessly in the face of destabilizing currents and winds.

The rights and wrongs of zebrafish  Behavioral phenotyping of zebrafish Book

The rights and wrongs of zebrafish Behavioral phenotyping of zebrafish


  • Author : Allan V. Kalueff
  • Publisher : Springer
  • Release Date : 2017-02-06
  • Genre: Medical
  • Pages : 327
  • ISBN 10 : 9783319337746

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The rights and wrongs of zebrafish Behavioral phenotyping of zebrafish Excerpt :

Animal models and tests have become increasingly important for biomedical research, enabling a better understanding of pathogenic pathways involved in various human disorders. Over the last decades, zebrafish (Danio rerio) have become a very popular model organism in biomedical research. Recently, this fish has entered the waters of neuroscience and biological psychiatry, quickly becoming an indispensable model species in this field. With a high genetic homology to humans (~75% based on coding regions), it is not surprising that humans and fish are very similar physiologically (and behaviorally). Therefore, it should not come as a surprise that zebrafish can be an excellent model of human neuropsychiatric disorders. While some classical psychiatrists may not too easily be persuaded by this generalization, the current book “The rights and wrongs of zebrafish: principles of behavioral phenotyping and CNS disease modeling” explains, in a domain-by-domain manner, how exactly zebrafish models can be used to target a wide range of human brain disorders and aberrant phenotypes. The contributors to this book are leading international scholars whose work spearheads innovative zebrafish neuroscience research around the world. Written by top experts in the field, this book makes for a useful, balanced and up-to-date reading that outlines the use of zebrafish to study the pathological mechanisms underlying neuropsychiatric disorders.