Biofilms and Implantable Medical Devices Book

Biofilms and Implantable Medical Devices


  • Author : Ying Deng
  • Publisher : Woodhead Publishing
  • Release Date : 2016-10-24
  • Genre: Technology & Engineering
  • Pages : 238
  • ISBN 10 : 9780081003985

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Biofilms and Implantable Medical Devices Excerpt :

Biofilms and Implantable Medical Devices: Infection and Control explores the increasing use of permanent and semi-permanent implants and indwelling medical devices. As an understanding of the growth and impact of biofilm formation on these medical devices and biomaterials is vital for protecting the health of the human host, this book provides readers with a comprehensive treatise on biofilms and their relationship with medical devices, also reporting on infections and associated strategies for prevention. Provides useful information on the fundamentals of biofilm problems in medical devices Discusses biofilm problems in a range of medical devices Focuses on strategies for prevention of biofilm formation

Biofilms in Human Diseases  Treatment and Control Book

Biofilms in Human Diseases Treatment and Control


  • Author : Sunil Kumar
  • Publisher : Springer Nature
  • Release Date : 2019-11-19
  • Genre: Medical
  • Pages : 311
  • ISBN 10 : 9783030307578

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Biofilms in Human Diseases Treatment and Control Excerpt :

This book highlights treatment strategies for bacterial biofilms in connection with a variety of human diseases. In particular, it reviews bacterial biofilm formation and its mechanism. Topics covered include biofilms in human health, the role of biofilms in mediating human diseases, and methods for testing bacterial biofilms. Further sections concentrate on biofilm-mediated diseases in different parts of the human gastrointestinal tract, while therapeutic strategies for biofilm control and natural agents that disrupt bacterial biofilms are also covered. Readers will also find the latest advances in probiotics and biofilms, as well as the use of probiotics to counteract biofilm-associated infections. Biofilms and antimicrobial resistance are discussed. Subsequent chapters address the management of inflammatory bowel disease via probiotics biofilms, as well as the role of probiotics bacteria in the treatment of human diseases associated with bacterial biofilms. The book is chiefly intended for clinicians/scientists in the fields of medical microbiology, applied microbiology, biochemistry, and biotechnology.

Microbial Biofilms in Healthcare Book

Microbial Biofilms in Healthcare


  • Author : Karen Vickery
  • Publisher : MDPI
  • Release Date : 2020-03-16
  • Genre: Medical
  • Pages : 166
  • ISBN 10 : 9783039284108

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Microbial Biofilms in Healthcare Excerpt :

Biofilms are ubiquitous and their presence in industry can lead to production losses. However, nowhere do biofilms impact human health and welfare as much as those that are found contaminating the healthcare environment, surgical instruments, equipment, and medical implantable devices. Approximately 70% of healthcare-associated infections are due to biofilm formation, resulting in increased patient morbidity and mortality. Biofilms formed on medical implants are recalcitrant to antibiotic treatment, which leaves implant removal as the principal treatment option. In this book, we investigate the role of biofilms in breast and dental implant disease and cancer. We include in vitro models for investigating treatment of chronic wounds and disinfectant action against Candida sp. Also included are papers on the most recent strategies for treating biofilm infection ranging from antibiotics incorporated into bone void fillers to antimicrobial peptides and quorum sensing.

Microbial Biofilms Book

Microbial Biofilms


  • Author : Mahmoud Ghannoum
  • Publisher : John Wiley & Sons
  • Release Date : 2020-08-11
  • Genre: Science
  • Pages : 404
  • ISBN 10 : 9781555817466

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Microbial Biofilms Excerpt :

An examination of the research and translational application to prevent and treat biofilm-associated diseases In the decade since the first edition of Microbial Biofilms was published, the interest in this field has expanded, spurring breakthrough research that has advanced the treatment of biofilm-associated diseases. This second edition takes the reader on an exciting, extensive review of bacterial and fungal biofilms, ranging from basic molecular interactions to innovative therapies, with particular emphasis on the division of labor in biofilms, new approaches to combat the threat of microbial biofilms, and how biofilms evade the host defense. Chapters written by established investigators cover recent findings, and contributions from investigators new to the field provide unique and fresh insights. Specifically, Microbial Biofilms provides state-of-the-art research in the field of bacterial and fungal biofilms detailed descriptions of the in vitro and in vivo models available to evaluate microbial biofilms future areas of research and their translational and clinical applications Microbial Biofilms is a useful reference for researchers and clinicians. It will also provide insight in the dynamic field of microbial biofilms for graduate and postgraduate students.

Biofilm Mediated Diseases  Causes and Controls Book

Biofilm Mediated Diseases Causes and Controls


  • Author : Rina Rani Ray
  • Publisher : Springer Nature
  • Release Date : 2021-05-05
  • Genre: Medical
  • Pages : 284
  • ISBN 10 : 9789811607455

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Biofilm Mediated Diseases Causes and Controls Excerpt :

This book reviews the current concepts in biofilm formation and its implications in human health and disease. The initial chapters introduce the mechanisms of biofilm formation and its composition. Subsequently, the chapters discuss the role of biofilm in acute and chronic infections. It also explores the pivotal role of both innate and adaptive immunity on the course of biofilm infection. In addition, the book elucidates the bacterial biofilm formation on implantable devices and the current approaches to its treatment and prevention. It analyzes the possible relationship between antimicrobial resistance and biofilm formation. Finally, the book also summarizes the current state-of-the-art therapeutic approaches for preventing and treating biofilms. This book is a useful resource for researchers in the field of microbiology, clinical microbiology, and also medical practitioners.

Biomaterials and Medical Device   Associated Infections Book

Biomaterials and Medical Device Associated Infections


  • Author : L Barnes
  • Publisher : Elsevier
  • Release Date : 2014-11-21
  • Genre: Technology & Engineering
  • Pages : 278
  • ISBN 10 : 9780857097224

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Biomaterials and Medical Device Associated Infections Excerpt :

Despite advances in materials and sterilisation, patients who receive biomaterials of medical device implants are still at risk of developing an infection around the implantation site. This book reviews the fundamentals of biomaterials and medical device related infections and methods and materials for the treatment and prevention of infection. The first part of the book provides readers with an introduction to the topic including analyses of biofilms, diagnosis and treatment of infection, pathology and topography. The second part of the book discusses a range of established and novel technologies and materials which have been designed to prevent infection. Provides analysis of biofilms and their relevance to implant associated infections. Assesses technologies for controlling biofilms. Considers advantages and disadvantages of in vivo infection studies.

Biofilms  Infection  and Antimicrobial Therapy Book

Biofilms Infection and Antimicrobial Therapy


  • Author : John L. Pace
  • Publisher : CRC Press
  • Release Date : 2005-08-29
  • Genre: Science
  • Pages : 512
  • ISBN 10 : 9781420028232

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Biofilms Infection and Antimicrobial Therapy Excerpt :

Rather than existing in a planktonic or free-living form, evidence indicates that microbes show a preference for living in a sessile form within complex communities called biofilms. Biofilms appear to afford microbes a survival advantage by optimizing nutrition, offering protection against hostile elements, and providing a network for cell-to-cell signaling and genetic exchange. Biofilms, Infection, and Antimicrobial Therapy provides an in-depth exploration of biofilms, offering broad background information, as well a detailed look at the serious concerns to which biofilm-associated infections give rise. Prosthetic device infections, such as those involving artificial heart valves, intravascular catheters, or prosthetic joints, are prime examples of biofilm-associated infections. With the increasing use of such devices in the modern practice of medicine, the prevalence of these infections is expected to increase. Unfortunately, one of the most troubling characteristics of microbes found in biofilms is a profound resistance to antimicrobial agents. As biofilm-associated infections are particularly difficult to treat, they result in significant mortality, morbidity, and increased economic burden. Clearly, a better understanding of the pathogenesis of these infections and improved means for prevention and treatment are urgently needed! InBiofilms, Infection, and Antimicrobial Therapy, Drs Pace, Rupp, and Finch assemble the contributions of more than 50 of the world’s leading authorities on microbial biofilms who present recent findings on antibacterial tolerance and bacterial persistence associated with biofilms and discuses the implications of those findings with regard to human health. They explore the molecular mechanisms of bacterial adherence, biofilm formation, regulation of biofilm maintenance, and cell-to-cell communication and present the latest information on various treatment protocols that should aid physicians in the treatment of these refractory and oft

Biofilm Infections Book

Biofilm Infections


  • Author : Thomas Bjarnsholt
  • Publisher : Springer
  • Release Date : 2014-10-11
  • Genre: Science
  • Pages : 314
  • ISBN 10 : 1489982280

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Biofilm Infections Excerpt :

This book will cover both the evidence for biofilms in many chronic bacterial infections as well as the problems facing these infections such as diagnostics and treatment regimes. A still increasing interest and emphasis on the sessile bacterial lifestyle biofilms has been seen since it was realized that that less than 0.1% of the total microbial biomass lives in the planktonic mode of growth. The term was coined in 1978 by Costerton et al. who defined the term biofilm for the first time.In 1993 the American Society for Microbiology (ASM) recognised that the biofilmmode of growth was relevant to microbiology. Lately many articles have been published on the clinical implications of bacterial biofilms. Both original articles and reviews concerning the biofilm problem are available.

Antibiofilm Agents Book

Antibiofilm Agents


  • Author : Kendra P. Rumbaugh
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-05-08
  • Genre: Science
  • Pages : 497
  • ISBN 10 : 9783642538339

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Antibiofilm Agents Excerpt :

This book provides a survey of recent advances in the development of antibiofilm agents for clinical and environmental applications. The fact that microbes exist in structured communities called biofilms has slowly become accepted within the medical community. We now know that over 80% of all infectious diseases are biofilm-related; however, significant challenges still lie in our ability to diagnose and treat these extremely recalcitrant infections. Written by experts from around the globe, this book offers a valuable resource for medical professionals seeking to treat biofilm-related disease, academic and industry researchers interested in drug discovery and instructors who teach courses on microbial pathogenesis and medical microbiology.

The Chemistry of Inorganic Biomaterials Book

The Chemistry of Inorganic Biomaterials


  • Author : Christopher Spicer
  • Publisher : Royal Society of Chemistry
  • Release Date : 2021-08-18
  • Genre: Science
  • Pages : 323
  • ISBN 10 : 9781788017534

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The Chemistry of Inorganic Biomaterials Excerpt :

This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.

Bone and Joint Infections Book

Bone and Joint Infections


  • Author : W. Zimmerli
  • Publisher : John Wiley & Sons
  • Release Date : 2015-01-27
  • Genre: Science
  • Pages : 429
  • ISBN 10 : 9781118581773

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Bone and Joint Infections Excerpt :

Infections of the bones (osteomyelitis) and joints (septic arthritis) are serious health problems which require antibiotics and often surgery. Awareness among health professionals of the causes and treatment options for various types of bone and joint infections is essential for effective resolution. Bone and Joint Infections takes a multidisciplinary approach in covering the diagnostic and therapeutic treatment of osteomyelitis and septic arthritis, including different types of implant-associated infections. Correct and rapid diagnosis of bone and joint infection is crucial, and requires the input of a variety of specialists. Bone and Joint Infection takes a similarly collaborative and comprehensive approach, including chapters authored by clinicians, laboratory specialists, and surgeons. Covering the basic microbiology and clinical aspects of bone and joint infection, this book will be a valuable resource both for researchers in the lab and for physicians and surgeons seeking a comprehensive reference on osteomyelitis and septic arthritis.

Nitric Oxide Donors Book

Nitric Oxide Donors


  • Author : Amedea Seabra
  • Publisher : Academic Press
  • Release Date : 2017-03-17
  • Genre: Medical
  • Pages : 364
  • ISBN 10 : 9780128134597

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Nitric Oxide Donors Excerpt :

Nitric Oxide Donors: Biomedical Applications and Perspectives presents the current state of art, challenges and innovations in the design of therapeutics nitric oxide donors with great impact in several aspects of human physiology and pathophysiology. Although considerable innovative progress has been achieved using Nitric Oxide donors in biomedical applications, certain drawbacks still need to be overcome to successfully translate these research innovations into clinical applications. This book encompasses several topics on nitric oxide such as its sources and biological properties; its performance in the cardiovascular and neurologic systems, in the human skin and its application in the treatment of neglected diseases, neurodegenerative disorders, and cancer. Additionally, it covers its role in inflammation and immunity, penile erection function, photodynamic therapy, antimicrobial activities. It also discusses the future of nitric oxide donors in combination with other therapeutic drugs, in implantable sensors, and nitric oxide releasing hydrogels and medical devices for topical applications. The book is a valuable source for researchers on different areas of biomedical field who are interested in the improvements that these molecules can make in the treatment of several conditions. Provides background information about biology and chemistry of nitric oxide Discusses the state-of-the-art in the design of nitric oxide releasing nanomaterials for biomedical applications Covers the usage of nitric oxide donors in the treatment of several conditions, such as cancer, human skin, cardiovascular system, and immunity Discusses the future of nitric oxide donors and their FDA approval

Disinfection and Decontamination Book

Disinfection and Decontamination


  • Author : Gurusamy Manivannan
  • Publisher : CRC Press
  • Release Date : 2007-10-04
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 1420008455

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Disinfection and Decontamination Excerpt :

In the battle between humans and microbes, knowledge may be not only the best weapon but also the best defense. Pulling contributions from 34 experts into a unified presentation, Disinfection and Decontamination: Principles, Applications, and Related Issues provides coverage that is both sophisticated and practical. The book reviews the fundamentals, explores the interdisciplinary nature of the science, and includes discussions of regulatory and legal issues. While the chapters present in depth coverage of infections in hospitals, they also widen their scope to include laboratories outside the healthcare environment. Based on practical experience, the volume examines recent advances in the research, development, and applications for disinfection and decontamination in many different settings. The chapters address, and supply insight into, the issues found with infectious disease, devices and new materials for implantation, principles, mechanisms, testing methods and strategies, and various applications. They also cover current research and best practice for ways to reduce infection caused by devices. The book’s emphasis on new technologies highlights the need for safer biocides and microbiological concerns in the manufacturing environment. The broad focus combined with the global, interdisciplinary panel of authors gives you a snapshot of disease transmission, perspectives on infectious challenges and solutions in a global perspective, and an understanding of global governance. The book offers in depth information on specific topics and an understanding of the fundamentals, giving you a starting point and precise information for resolving problems.

Racing for the Surface Book

Racing for the Surface


  • Author : Bingyun Li
  • Publisher : Springer Nature
  • Release Date : 2020-03-02
  • Genre: Medical
  • Pages : 650
  • ISBN 10 : 9783030344757

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Racing for the Surface Excerpt :

This book covers the latest research in biofilm, infection, and antimicrobial strategies in reducing and treating musculoskeletal, skin, transfusion, implant-related infections, etc. Topics covered include biofilms, small colony variants, antimicrobial biomaterials (antibiotics, antimicrobial peptides, hydrogels, bioinspired interfaces, immunotherapeutic approaches, and more), antimicrobial coatings, engineering and 3D printing, antimicrobial delivery vehicles, and perspectives on clinical impacts. Antibiotic resistance, which shifts the race toward bacteria, and strategies to reduce antibiotic resistance, are also briefly touched on. Combined with its companion volume, Racing for the Surface: Pathogenesis of Implant Infection and Advanced Antimicrobial Strategies, this book bridges the gaps between infection and tissue engineering, and is an ideal book for academic researchers, clinicians, industrial engineers and scientists, governmental representatives in national laboratories, and advanced undergraduate students and post-doctoral fellows who are interested in infection, microbiology, and biomaterials and devices.