Bioinformatics for Biomedical Science and Clinical Applications Book

Bioinformatics for Biomedical Science and Clinical Applications


  • Author : K-H Liang
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Genre: Computers
  • Pages : 170
  • ISBN 10 : 9781908818232

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Bioinformatics for Biomedical Science and Clinical Applications Excerpt :

Contemporary biomedical and clinical research is undergoing constant development thanks to the rapid advancement of various high throughput technologies at the DNA, RNA and protein levels. These technologies can generate vast amounts of raw data, making bioinformatics methodologies essential in their use for basic biomedical and clinical applications. Bioinformatics for biomedical science and clinical applications demonstrates what these cutting-edge technologies can do and examines how to design an appropriate study, including how to deal with data and address specific clinical questions. The first two chapters consider Bioinformatics and analysis of the human genome. The subsequent three chapters cover the introduction of Transcriptomics, Proteomics and Systems biomedical science. The remaining chapters move on to critical developments, clinical information and conclude with domain knowledge and adaptivity. A coherent presentation of concepts, methodologies and practical tools that systematically lead to significant discoveries in the biomedical and clinical area Real examples of cutting edge discoveries The introduction of study types and technologies for all the DNA, RNA and protein levels

Statistical Advances in the Biomedical Sciences Book

Statistical Advances in the Biomedical Sciences


  • Author : Atanu Biswas
  • Publisher : John Wiley & Sons
  • Release Date : 2007-12-14
  • Genre: Mathematics
  • Pages : 616
  • ISBN 10 : 0470181192

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Statistical Advances in the Biomedical Sciences Excerpt :

The Most Comprehensive and Cutting-Edge Guide to Statistical Applications in Biomedical Research With the increasing use of biotechnology in medical research and the sophisticated advances in computing, it has become essential for practitioners in the biomedical sciences to be fully educated on the role statistics plays in ensuring the accurate analysis of research findings. Statistical Advances in the Biomedical Sciences explores the growing value of statistical knowledge in the management and comprehension of medical research and, more specifically, provides an accessible introduction to the contemporary methodologies used to understand complex problems in the four major areas of modern-day biomedical science: clinical trials, epidemiology, survival analysis, and bioinformatics. Composed of contributions from eminent researchers in the field, this volume discusses the application of statistical techniques to various aspects of modern medical research and illustrates how these methods ultimately prove to be an indispensable part of proper data collection and analysis. A structural uniformity is maintained across all chapters, each beginning with an introduction that discusses general concepts and the biomedical problem under focus and is followed by specific details on the associated methods, algorithms, and applications. In addition, each chapter provides a summary of the main ideas and offers a concluding remarks section that presents novel ideas, approaches, and challenges for future research. Complete with detailed references and insight on the future directions of biomedical research, Statistical Advances in the Biomedical Sciences provides vital statistical guidance to practitioners in the biomedical sciences while also introducing statisticians to new, multidisciplinary frontiers of application. This text is an excellent reference for graduate- and PhD-level courses in various areas of biostatistics and the medical sciences and also serves as a valuable tool

Computational Methods With Applications In Bioinformatics Analysis Book

Computational Methods With Applications In Bioinformatics Analysis


  • Author : Tsai Jeffrey J P
  • Publisher : World Scientific
  • Release Date : 2017-06-09
  • Genre: Computers
  • Pages : 232
  • ISBN 10 : 9789813207998

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Computational Methods With Applications In Bioinformatics Analysis Excerpt :

This compendium contains 10 chapters written by world renowned researchers with expertise in semantic computing, genome sequence analysis, biomolecular interaction, time-series microarray analysis, and machine learning algorithms. The salient feature of this book is that it highlights eight types of computational techniques to tackle different biomedical applications. These techniques include unsupervised learning algorithms, principal component analysis, fuzzy integral, graph-based ensemble clustering method, semantic analysis, interolog approach, molecular simulations and enzyme kinetics. The unique volume will be a useful reference material and an inspirational read for advanced undergraduate and graduate students, computer scientists, computational biologists, bioinformatics and biomedical professionals.

Application of Clinical Bioinformatics Book

Application of Clinical Bioinformatics


  • Author : Xiangdong Wang
  • Publisher : Springer
  • Release Date : 2016-03-31
  • Genre: Medical
  • Pages : 398
  • ISBN 10 : 9789401775434

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Application of Clinical Bioinformatics Excerpt :

This book elucidates how genetic, biological and medical information can be applied to the development of personalized healthcare, medication and therapies. Focusing on aspects of the development of evidence-based approaches in bioinformatics and computational medicine, including data integration, methodologies, tools and models for clinical and translational medicine, it offers an essential introduction to clinical bioinformatics for clinical researchers and physicians, medical students and teachers, and scientists working with human disease-based omics and bioinformatics. Dr. Xiangdong Wang is a distinguished Professor of Medicine. He is Director of Shanghai Institute of Clinical Bioinformatics, Director of Fudan University Center for Clinical Bioinformatics, Deputy Director of Shanghai Respiratory Research Institute, Director of Biomedical Research Center, Fudan University Zhongshan Hospital, Shanghai, China; Dr. Christian Baumgartner is a Professor of Health Care and Biomedical Engineering at Institute of Health Care Engineering with European Notified Body of Medical Devices, Graz University of Technology, Graz, Austria; Dr. Denis Shields is a Professor of Clinical Bioinformatics at Conway Institute, Belfield, Dublin, Ireland; Dr. Hong-Wen Deng is a Professor at Department of Biostatistics and Bioinformatics, Tulane University School of Public Health and Tropical Medicine, USA; Dr. Jacques S Beckmann is a Professor and Director of Section of Clinical Bioinformatics, Swiss Institute of Bioinformatics, Switzerland.

Biological Data Mining and Its Applications in Healthcare Book

Biological Data Mining and Its Applications in Healthcare


  • Author : Xiaoli Li
  • Publisher : World Scientific
  • Release Date : 2013-11-28
  • Genre: Computers
  • Pages : 436
  • ISBN 10 : 9789814551021

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Biological Data Mining and Its Applications in Healthcare Excerpt :

Biologists are stepping up their efforts in understanding the biological processes that underlie disease pathways in the clinical contexts. This has resulted in a flood of biological and clinical data from genomic and protein sequences, DNA microarrays, protein interactions, biomedical images, to disease pathways and electronic health records. To exploit these data for discovering new knowledge that can be translated into clinical applications, there are fundamental data analysis difficulties that have to be overcome. Practical issues such as handling noisy and incomplete data, processing compute-intensive tasks, and integrating various data sources, are new challenges faced by biologists in the post-genome era. This book will cover the fundamentals of state-of-the-art data mining techniques which have been designed to handle such challenging data analysis problems, and demonstrate with real applications how biologists and clinical scientists can employ data mining to enable them to make meaningful observations and discoveries from a wide array of heterogeneous data from molecular biology to pharmaceutical and clinical domains. Contents:Sequence Analysis:Mining the Sequence Databases for Homology Detection: Application to Recognition of Functions of Trypanosoma brucei brucei Proteins and Drug Targets (G Ramakrishnan, V S Gowri, R Mudgal, N R Chandra and N Srinivasan)Identification of Genes and Their Regulatory Regions Based on Multiple Physical and Structural Properties of a DNA Sequence (Xi Yang, Nancy Yu Song and Hong Yan)Mining Genomic Sequence Data for Related Sequences Using Pairwise Statistical Significance (Yuhong Zhang and Yunbo Rao)Biological Network Mining:Indexing for Similarity Queries on Biological Networks (Günhan Gülsoy, Md Mahmudul Hasan, Yusuf Kavurucu and Tamer Kahveci)Theory and Method of Completion for a Boolean Regulatory Network Using Observed Data (Takeyuki Tamura and Tatsuya Akutsu)Mining Frequent Subgraph Patterns for Classifying Biologica

Bioinformatics Basics Book

Bioinformatics Basics


  • Author : Lukas K. Buehler
  • Publisher : CRC Press
  • Release Date : 2005-06-23
  • Genre: Science
  • Pages : 360
  • ISBN 10 : 9781482292343

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Bioinformatics Basics Excerpt :

Every researcher in genomics and proteomics now has access to public domain databases containing literally billions of data entries. However, without the right analytical tools, and an understanding of the biological significance of the data, cataloging and interpreting the molecular evolutionary processes buried in those databases is difficult, if not impossible. The first editon of Bioinformatics Basics: Applications in Biological Science and Medicine answered the scientific community’s need to learn about the bioinformatic tools available to them. That the book continues to be a best seller clearly demonstrates the authors’ ability to provide scientists with the understanding to apply those tools to their research. Currently, it is being used as a reference text at MIT and other prestigious institutions. Recognizing the important advances in bioinformatices since their last edition, Buehler and Rashidi have produced a completely revised and updated version of their pioneering work. To allow scientists to utilize significant databases from around the world, the authors consider some fresh approaches to data analysis while identifying computing techniques that will help them manage the massive flow of information their science requires. New to the second edition: Provides a more detailed view of the field while continuing to focus on the global concept approach that popularized the first edition. Offers the latest approaches to data analysis Introduces recent developments in genomics, microarrays, proteomics, genome mapping, and more. Adds two new sections offering insights from other experts in bioinformatics. Bioinformatics Basics is not intended to serve as a training manual for bioinformaticians. Instead, it’s designed to help the general scientific community gain a thorough understanding of what bioinformatics tools are available to them and the best ways these tools can be utilized and adapted to meet the needs of their specific interests and projects.

Translational Bioinformatics Applications in Healthcare Book
Score: 5
From 1 Ratings

Translational Bioinformatics Applications in Healthcare


  • Author : Khalid Raza
  • Publisher : CRC Press
  • Release Date : 2021-04-20
  • Genre: Technology & Engineering
  • Pages : 210
  • ISBN 10 : 9781000375237

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Translational Bioinformatics Applications in Healthcare Excerpt :

Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medic

Translational Bioinformatics Applications in Healthcare Book
Score: 5
From 1 Ratings

Translational Bioinformatics Applications in Healthcare


  • Author : Khalid Raza
  • Publisher : CRC Press
  • Release Date : 2021-04-20
  • Genre: Technology & Engineering
  • Pages : 224
  • ISBN 10 : 9781000375169

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Translational Bioinformatics Applications in Healthcare Excerpt :

Translational bioinformatics (TBI) involves development of storage, analytics, and advanced computational methods to harvest knowledge from voluminous biomedical and genomic data into 4P healthcare (proactive, predictive, preventive, and participatory). Translational Bioinformatics Applications in Healthcare offers a detailed overview on concepts of TBI, biological and clinical databases, clinical informatics, and pertinent real-case applications. It further illustrates recent advancements, tools, techniques, and applications of TBI in healthcare, including Internet of Things (IoT) potential, toxin databases, medical image analysis and telemedicine applications, analytics of COVID-19 CT images, viroinformatics and viral diseases, and COVID-19–related research. Covers recent technologies such as Blockchain, IoT, and Big data analytics in bioinformatics Presents the role of translational bioinformatic methods in the field of viroinformatics, as well as in drug development and repurposing Includes translational healthcare and NGS for clinical applications Illustrates translational medicine systems and their applications in better healthcare Explores medical image analysis with focus on CT images and novel coronavirus disease detection Aimed at researchers and graduate students in computational biology, data mining and knowledge discovery, algorithms and complexity, and interdisciplinary fields of studies, including bioinformatics, health-informatics, biostatistics, biomedical engineering, and viroinformatics. Khalid Raza is an Assistant Professor, the Department of Computer Science, Jamia Millia Islamia (Central University), New Delhi. His research interests include translational bioinformatics, computational intelligence methods and its applications in bioinformatics, viroinformatics, and health informatics. Nilanjan Dey is an Associate Professor, the Department of Computer Science and Engineering, JIS University, Kolkata, India. His research interests include medic

Java for Bioinformatics and Biomedical Applications Book

Java for Bioinformatics and Biomedical Applications


  • Author : Harshawardhan Bal
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-01-16
  • Genre: Science
  • Pages : 342
  • ISBN 10 : 9780387372372

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Java for Bioinformatics and Biomedical Applications Excerpt :

Medical science and practice have undergone fundamental changes in the last 5 years, as large-scale genome projects have resulted in the sequencing of a number of important microbial, plant and animal genomes. This book aims to combine industry standard software engineering and design principles with genomics, bioinformatics and cancer research. Rather than an exercise in learning a programming platform, the text focuses on useful analytical tools for the scientific community.

SOFSEM 2018  Theory and Practice of Computer Science Book

SOFSEM 2018 Theory and Practice of Computer Science


  • Author : A Min Tjoa
  • Publisher : Springer
  • Release Date : 2018-01-12
  • Genre: Computers
  • Pages : 698
  • ISBN 10 : 9783319731179

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SOFSEM 2018 Theory and Practice of Computer Science Excerpt :

This book constitutes the refereed proceedings of the 44th International Conference on Current Trends in Theory and Practice of Computer Science, SOFSEM 2018, held in Krems, Austria, in January/February 2018. The 48 papers presented in this volume were carefully reviewed and selected from 97 submissions. They were organized in topical sections named: foundations of computer science; software engineering: advances methods, applications, and tools; data, information and knowledge engineering; network science and parameterized complexity; model-based software engineering; computational models and complexity; software quality assurance and transformation; graph structure and computation; business processes, protocols, and mobile networks; mobile robots and server systems; automata, complexity, completeness; recognition and generation; optimization, probabilistic analysis, and sorting; filters, configurations, and picture encoding; machine learning; text searching algorithms; and data model engineering.

Computer Aided Applications in Pharmaceutical Technology Book

Computer Aided Applications in Pharmaceutical Technology


  • Author : Jelena Djuris
  • Publisher : Elsevier
  • Release Date : 2013-04-10
  • Genre: Medical
  • Pages : 300
  • ISBN 10 : 9781908818324

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Computer Aided Applications in Pharmaceutical Technology Excerpt :

Research and development in the pharmaceutical industry is a time-consuming and expensive process, making it difficult for newly developed drugs to be formulated into commercially available products. Both formulation and process development can be optimized by means of statistically organized experiments, artificial intelligence and other computational methods. Simultaneous development and investigation of pharmaceutical products and processes enables application of quality by design concept that is being promoted by the regulatory authorities worldwide. Computer-aided applications in pharmaceutical technology covers the fundamentals of experimental design application and interpretation in pharmaceutical technology, chemometric methods with emphasis of their application in process control, neural computing (artificial neural networks, fuzzy logic and decision trees, evolutionary computing and genetic algorithms, self-organizing maps), computer-aided biopharmaceutical characterization as well as application of computational fluid dynamics in pharmaceutical technology. All of these techniques are essential tools for successful building of quality into pharmaceutical products and processes from the early stage of their development to selection of the optimal ones. In addition to theoretical aspects of various methods, the book provides numerous examples of their application in the field of pharmaceutical technology. A comprehensive review of the current state of the art on various computer aided applications in pharmaceutical technology Case studies are presented in order to facilitate understanding of various concepts in computer-aided applications

Translational Bioinformatics in Healthcare and Medicine Book

Translational Bioinformatics in Healthcare and Medicine


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2021-05-13
  • Genre: Business & Economics
  • Pages : 254
  • ISBN 10 : 9780323898904

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Translational Bioinformatics in Healthcare and Medicine Excerpt :

Translational Bioinformatics in Healthcare and Medicine offers an overview of main principles of bioinformatics, biological databases, clinical informatics, health informatics, viroinformatics and real-case applications of translational bioinformatics in healthcare. Written by experts from both technology and clinical sides, the content brings together essential knowledge to make the best of recent advancements of the field. The book discusses topics such as next generation sequence analysis, genomics in clinical care, IoT applications, blockchain technology, patient centered interoperability of EHR, health data mining, and translational bioinformatics methods for drug discovery and drug repurposing. In addition, it discusses the role of bioinformatics in cancer research and viroinformatics approaches to counter viral diseases through informatics. This is a valuable resource for bioinformaticians, clinicians, healthcare professionals, graduate students and several members of biomedical field who are interested in learning more about how bioinformatics can impact in their research and practice. Covers recent advancements in translational bioinformatics and its healthcare applications Discusses integrative and multidisciplinary approaches to U-healthcare systems development and management Bridges the gap among various knowledge domains in the field, integrating both technological and clinical knowledge into practical content

Open Source Software in Life Science Research Book

Open Source Software in Life Science Research


  • Author : Lee Harland
  • Publisher : Elsevier
  • Release Date : 2012-10-31
  • Genre: Science
  • Pages : 582
  • ISBN 10 : 9781908818249

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Open Source Software in Life Science Research Excerpt :

The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems. The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry. Discusses a broad range of applications from a variety of sectors Provides a unique perspective on work normally performed behind closed doors Highlights the criteria used to compare and assess different approaches to solving problems

An Introduction to Pharmaceutical Sciences Book
Score: 5
From 1 Ratings

An Introduction to Pharmaceutical Sciences


  • Author : Jiben Roy
  • Publisher : Elsevier
  • Release Date : 2011-07-25
  • Genre: Medical
  • Pages : 446
  • ISBN 10 : 9781908818041

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An Introduction to Pharmaceutical Sciences Excerpt :

This textbook is written as a unified approach to various topics, ranging from drug discovery to manufacturing, techniques and technology, regulation and marketing. The key theme of the book is pharmaceuticals - what every student of pharmaceutical sciences should know: from the active pharmaceutical ingredients to the preparation of various dosage forms along with the relevant chemistry, this book makes pharmaceuticals relevant to undergraduate students of pharmacy and pharmaceutical sciences. This book explains how a particular drug was discovered and then converted from lab-scale to manufacturing scale, to the market. It explains the motivation for drug discovery, the reaction chemistry involved, experimental difficulties, various dosage forms and the reasoning behind them, mechanism of action, quality assurance and role of regulatory agencies. After having a course based on this book, the student will be able to understand: 1) the career prospects in the pharmaceutical industry, 2) the need for interdisciplinary teamwork in science, 3) the techniques and technology involved in making pharmaceuticals starting from bulk drugs, and 4) different dosage forms and critical factors in the development of pharmaceutical formulations in relation to the principles of chemistry. A few blockbuster drugs including atorvastatin, sildanefil, ranitidine, ciprofloxacin, amoxicillin, and the longest serving drugs such as aspirin and paracetamol are discussed in detail. Finally, the book also covers the important current pharmaceutical issues like quality control, safety, counterfeiting and abuse of drugs, and future prospects for pharmaceutical industry. Unified approach explaining drug discovery, bulk drug manufacturing, formulation of dosage forms, with pharmacological and therapeutic actions Manufacturing processes of representative active pharmaceutical ingredients and their chemistry plus formulation of dosage forms presented in this book are based on actual industrial proces

Biocomputation and Biomedical Informatics  Case Studies and Applications Book
Score: 3
From 1 Ratings

Biocomputation and Biomedical Informatics Case Studies and Applications


  • Author : Lazakidou, Athina A.
  • Publisher : IGI Global
  • Release Date : 2009-11-30
  • Genre: Computers
  • Pages : 356
  • ISBN 10 : 9781605667690

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Biocomputation and Biomedical Informatics Case Studies and Applications Excerpt :

"This book provides a compendium of terms, definitions, and explanations of concepts, processes, and acronyms"--Provided by publisher.