Biomaterials for Treating Skin Loss Book

Biomaterials for Treating Skin Loss


  • Author : D P Orgill
  • Publisher : Elsevier
  • Release Date : 2009-01-28
  • Genre: Medical
  • Pages : 256
  • ISBN 10 : 9781845695545

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Biomaterials for Treating Skin Loss Excerpt :

The primary causes of wounds requiring skin replacement are severe burns and ulcers. Materials must provide an effective temporary barrier, promote healing and minimise scarring. Massive improvements have been made to skin repair biomaterials in the last ten years with widespread adoption of new developments in the medical sector. This book provides a comprehensive review of the range of biomaterials for treating skin loss. Part one discusses the basics of skin replacement with chapters on such topics as markets and regulation, biomechanics and the biological environment of skin. Part two then reviews epidermal and dermal replacement technology with chapters on such topics as alternative delivery of keratinocytes, collagen-based and human origin-based dermal replacement, and lyophilized xenogenic products. The final section explores combined dermis and epidermal replacement technologies and provides a round-up of skin replacement principles. With its distinguished editors and international team of contributors, Biomaterials for treating skin loss is a standard reference for those researching skin replacement technologies, particularly those interested in treating burns and ulcers. Comprehensively reviews the range of biomaterials for treating skin loss and skin replacement principles Examines the basis of skin loss from products and markets through to regulation and the biological environment of skin Highlights developments in epidermal and dermal replacement technology covering topics such as collagen-based and human origin-based dermal replacement

Skin Tissue Engineering and Regenerative Medicine Book

Skin Tissue Engineering and Regenerative Medicine


  • Author : Mohammad Albanna
  • Publisher : Academic Press
  • Release Date : 2016-01-14
  • Genre: Technology & Engineering
  • Pages : 466
  • ISBN 10 : 9780128017975

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Skin Tissue Engineering and Regenerative Medicine Excerpt :

The skin is the largest human organ system. Loss of skin integrity due to injury or illness results in a substantial physiologic imbalance and ultimately in severe disability or death. From burn victims to surgical scars and plastic surgery, the therapies resulting from skin tissue engineering and regenerative medicine are important to a broad spectrum of patients. Skin Tissue Engineering and Regenerative Medicine provides a translational link for biomedical researchers across fields to understand the inter-disciplinary approaches which expanded available therapies for patients and additional research collaboration. This work expands on the primary literature on the state of the art of cell therapies and biomaterials to review the most widely used surgical therapies for the specific clinical scenarios. Explores cellular and molecular processes of wound healing, scar formation, and dermal repair Includes examples of animal models for wound healing and translation to the clinical world Presents the current state of, and clinical opportunities for, extracellular matrices, natural biomaterials, synthetic biomaterials, biologic skin substitutes, and adult and fetal stem and skin cells for skin regenerative therapies and wound management Discusses new innovative approaches for wound healing including skin bioprinting and directed cellular therapies

Textbook on Scar Management Book

Textbook on Scar Management


  • Author : Luc Téot
  • Publisher : Springer Nature
  • Release Date : 2020-12-07
  • Genre: Medical
  • Pages : 553
  • ISBN 10 : 9783030447663

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Textbook on Scar Management Excerpt :

This text book is open access under a CC BY 4.0 license. Written by a group of international experts in the field and the result of over ten years of collaboration, it allows students and readers to gain to gain a detailed understanding of scar and wound treatment – a topic still dispersed among various disciplines. The content is divided into three parts for easy reference. The first part focuses on the fundamentals of scar management, including assessment and evaluation procedures, classification, tools for accurate measurement of all scar-related elements (volume density, color, vascularization), descriptions of the different evaluation scales. It also features chapters on the best practices in electronic-file storage for clinical reevaluation and telemedicine procedures for safe remote evaluation. The second section offers a comprehensive review of treatment and evidence-based technologies, presenting a consensus of the various available guidelines (silicone, surgery, chemical injections, mechanical tools for scar stabilization, lasers). The third part evaluates the full range of emerging technologies offered to physicians as alternative or complementary solutions for wound healing (mechanical, chemical, anti-proliferation). Textbook on Scar Management will appeal to trainees, fellows, residents and physicians dealing with scar management in plastic surgery, dermatology, surgery and oncology, as well as to nurses and general practitioners

Advanced Wound Repair Therapies Book

Advanced Wound Repair Therapies


  • Author : David Farrar
  • Publisher : Elsevier
  • Release Date : 2011-06-21
  • Genre: Medical
  • Pages : 672
  • ISBN 10 : 9780857093301

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Advanced Wound Repair Therapies Excerpt :

Wound repair is an important and growing sector of the medical industry with increasingly sophisticated biomaterials and strategies being developed to treat wounds. Advanced wound repair therapies provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds. Part one provides an introduction to chronic wounds, with chapters covering dysfunctional wound healing, scarring and scarless wound healing and monitoring of wounds. Part two covers biomaterial therapies for chronic wounds, including chapters on functional requirements of wound repair biomaterials, polymeric materials for wound dressings and interfacial phenomena in wound healing. In part three, molecular therapies for chronic wounds are discussed, with chapters on topics such as drug delivery, molecular and gene therapies and antimicrobial dressings. Part four focuses on biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derived scaffolds and stem cell therapies for wound repair. Finally, part five covers physical stimulation therapies for chronic wounds, including electrical stimulation, negative pressure therapy and mechanical debriding devices. With its distinguished editor and international team of contributors, Advanced wound repair therapies is an essential reference for researchers and materials scientists in the wound repair industry, as well as clinicians and those with an academic research interest in the subject. Provides readers with up-to-date information on current and emerging biomaterials and advanced therapies concerned with healing surgical and chronic wounds Chapters include the role of micro-organisms and biofilms in dysfunctional wound healing, tissue-biomaterial interaction and electrical stimulation for wound healing Covers biologically-derived and cell-based therapies for chronic wounds, including engineered tissues, biologically-derive

Marine Biological Materials of Invertebrate Origin Book

Marine Biological Materials of Invertebrate Origin


  • Author : Hermann Ehrlich
  • Publisher : Springer Nature
  • Release Date : 2019-10-17
  • Genre: Technology & Engineering
  • Pages : 329
  • ISBN 10 : 9783319924830

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Marine Biological Materials of Invertebrate Origin Excerpt :

The work is a source of modern knowledge on biomineralization, biomimetics and bioinspired materials science with respect to marine invertebrates. The author gives the most coherent analysis of the nature, origin and evolution of biocomposites and biopolymers isolated from and observed in the broad diversity of marine invertebrate organisms and within their unusual structural formations. The basic format is that of a major review article, with liberal use of references to original literature. There is a wealth of new and newly synthesized information, including dozens of previously unpublished images of unique marine creatures and structures from nano- to microscale including high-resolution scanning and transmission electron micrographs. The material is organized effectively along both biological (phyla) and functional lines. The classification of biological materials of marine origin is proposed and discussed. Much of the pertinent data is organized into tables, and extensive use is made of electron micrographs and line drawings. Several modern topics e.g. “biomineralization- demineralization-remineralization phenomena”, or “phenomenon of multiphase biomineralization”, are discussed in details. Traditionally, such current concepts as hierarchical organization of biocomposites and skeletal structures, structural bioscaffolds, biosculpturing, biomimetism and bioinspiration as tools for the design of innovative materials are critically analyzed from both biological and materials science point of view using numerous unique examples of marine origin. This monograph reviews the most relevant advances in the marine biomaterials research field, pointing out several approaches being introduced and explored by distinct laboratories.

Drug Device Combination Products Book

Drug Device Combination Products


  • Author : Andrew Lewis
  • Publisher : Elsevier
  • Release Date : 2009-12-15
  • Genre: Medical
  • Pages : 560
  • ISBN 10 : 9781845697488

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Drug Device Combination Products Excerpt :

Drug delivery systems represent a vast area of research and development within biomaterials and medicine and the demand for sophisticated drug delivery devices continues to drive novel product development. Advanced drug delivery devices can offer significant advantages over conventional drugs and devices alone, such as increased efficiency, improved performance and convenience. The purpose of this book is to illustrate how effective drug delivery can be achieved by means other than tablets. The book will provide a thorough analysis of the fundamentals, applications and new technologies of drug-device combination products for use throughout the human body. Part one provides readers with an introduction and background to the field. Chapters in Part two discuss areas of application such as catheter based products, drug eluting stents and beads and anti-biotic loaded cements. Part three covers the development of drug device combination products with chapters on such topics as pre-clinical testing, sterilisation, patent issues and regulation of drug device combination products. With its distinguished editor and team of international contributors, Drug-device combination products: delivery technologies and applications is an invaluable reference for product development specialists, materials scientists and engineers in the biomedical industry and academia as well as those concerned with drug delivery. Illustrates how effective drug delivery can be achieved by means other than tablets providing readers with a comprehensive introduction and background to the field Provides a thorough analysis of the fundamentals, applications and new technologies of drug device combination products Discusses areas of application such as catheter based products and reviews the development of drug device combination products including pre-clinical testing and sterilisation

Developments in Tissue Engineered and Regenerative Medicine Products Book

Developments in Tissue Engineered and Regenerative Medicine Products


  • Author : Joydeep Basu
  • Publisher : Elsevier
  • Release Date : 2012-04-19
  • Genre: Technology & Engineering
  • Pages : 226
  • ISBN 10 : 9781908818119

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Developments in Tissue Engineered and Regenerative Medicine Products Excerpt :

Developments in tissue engineered and regenerative medicine products summarizes recent developments in tissue engineering and regenerative medicine with an emphasis on commercialization and product development. Features of current cell therapy and tissue engineered products which have facilitated successful commercialization are emphasized and roadblocks to successful product development are also highlighted. Preclinical and clinical testing of tissue engineered and regenerative medicine products, regulatory, quality control, manufacturing issues, as well as generating and securing intellectual property and freedom to operate considerations are presented. This book represents a complete 'how-to' manual for the development of tissue engineered and regenerative medicine products from conceptualization to clinical trial to manufacturing. Addresses practical considerations for the field of tissue engineering and regenerative medicine from the perspective of the biotechnology industry Written as a manual for tissue engineering and regenerative medicine product development applicable to the US and EU Illustrates pathway integration of science and business required for successful product development

Wound Care Essentials Book

Wound Care Essentials


  • Author : Sharon Baranoski
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2020-05-11
  • Genre: Medical
  • Pages : 632
  • ISBN 10 : 9781975128890

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Wound Care Essentials Excerpt :

Looking for an up-to-date, how-to, evidence-based wound care reference? The newly revised Wound Care Essentials, 5th Edition is the comprehensive seminal resource, offering the latest evidence, guidelines and information to assist the interprofessional skin and wound care team translate knowledge into practice.

The Hip Resurfacing Handbook Book

The Hip Resurfacing Handbook


  • Author : K De Smet
  • Publisher : Elsevier
  • Release Date : 2013-04-22
  • Genre: Technology & Engineering
  • Pages : 576
  • ISBN 10 : 9780857096203

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The Hip Resurfacing Handbook Excerpt :

Hip resurfacing arthroplasty (HRA) using metal-on-metal bearings is an established but specialised technique in joint surgery. Based on the experience of leading experts in the field, The hip resurfacing handbook provides a comprehensive reference for all aspects of this important procedure. The first part of the book reviews and compares all the major hip resurfacing prostheses, their key design features, relevant surgical techniques and clinical results. Part two discusses clinical follow-up of the hip resurfacing patient, including pre- and post-operative examination, acoustic phenomena and rehabilitation. It also covers the use of techniques such as radiography and metal ion measurement, as well as bone scans, ultrasound, CT, MRI, PET and DEXA, to evaluate hip resurfacings. Part three reviews best practice in surgical technique, including the modified posterior and anterior approaches, as well as instrumentation, anaesthesia and revision surgery. Based on extensive retrieval studies, Part four includes examples of the main failure modes in HRA. The final part of the book includes patients’ own experiences, a comparison of HRA with total hip arthroplasty (THA), regulatory issues and relevant web sites. Comprehensive in its scope and authoritative in its coverage, The hip resurfacing handbook is a standard work for orthopaedic surgeons and all those involved in HRA. A standard work for orthopaedic surgeons and all those involved in HRA Reviews and compares all the major hip resurfacing prostheses, their key design features, relevant surgical techniques and clinical results Clinical follow-up of the patient is discussed

Extracellular Matrix derived Implants in Clinical Medicine Book

Extracellular Matrix derived Implants in Clinical Medicine


  • Author : Daniel L Mooradian
  • Publisher : Woodhead Publishing
  • Release Date : 2016-05-18
  • Genre: Technology & Engineering
  • Pages : 202
  • ISBN 10 : 9780081002193

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Extracellular Matrix derived Implants in Clinical Medicine Excerpt :

Extracellular Matrix-Derived Implants in Clinical Medicine comprehensively covers the emergence of tissue engineering and regenerative medicine over the past few decades, along with discussions of continuous funding and research. The book provides a state-of-the-art review of this increasingly important technology and how it is translating from bench to bedside. Part One of the book looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological, while Part Two examines the challenges in harvesting, processing, and manufacturing of extracellular matrices, with a final section reviewing the international regulatory environment and economics of tissue-based products. Addresses issues of tissue engineering and regenerative medicine from a biomaterials industry perspective Looks at the historical use of human and animal tissues, focusing on the main application areas, including cardiovascular, hard and soft tissue engineering, and neurological Examines the challenges in harvesting, processing, and manufacturing of extracellular matrices Reviews the international regulatory environment and economics of tissue-based products

Medical Nanotechnology and Nanomedicine Book

Medical Nanotechnology and Nanomedicine


  • Author : Harry F. Tibbals
  • Publisher : CRC Press
  • Release Date : 2017-12-19
  • Genre: Medical
  • Pages : 527
  • ISBN 10 : 9781351834148

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Medical Nanotechnology and Nanomedicine Excerpt :

Considering the fluid nature of nano breakthroughs—and the delicate balance between benefits and consequences as they apply to medicine—readers at all levels require a practical, understandable base of information about these developments to take greatest advantage of them. Medical Nanotechnology and Nanomedicine meets that need by introducing non-experts to nanomedicine and its evolving organizational infrastructure. This practical reference investigates the impact of nanotechnology on applications in medicine and biomedical sciences, and the broader societal and economic effects. Eschewing technological details, it focuses on enhancing awareness of the business, regulatory, and administrative aspects of medical applications. It gives readers a critical, balanced, and realistic evaluation of existing nanomedicine developments and future prospects—an ideal foundation upon which to plan and make decisions. Covers the use of nanotechnology in medical applications including imaging, diagnosis and monitoring, drug delivery systems, surgery, tissue regeneration, and prosthetics Part of the Perspectives in Nanotechnology series—which contains broader coverage of the societal implications of nanotechnology—this book can be used as a standalone reference. Organized by historical perspective, current status, and future prospects, this powerful book: Explores background, definitions and terms, and recent trends and forces in nanomedicine Surveys the landscape of nanomedicine in government, academia, and the private sector Reviews projected future directions, capabilities, sustainability, and equity of nanomedicine, and choices to be made regarding its use Includes graphical illustrations, references, and keywords to reinforce concepts and aid further research In its assessment of alternative and sometimes conflicting concepts proposed for the application of nanotechnology to medicine, this book surveys major initiatives and the work of leading labs and innovators. I

Mems for Biomedical Applications Book

Mems for Biomedical Applications


  • Author : Shekhar Bhansali
  • Publisher : Elsevier
  • Release Date : 2012-07-18
  • Genre: Technology & Engineering
  • Pages : 512
  • ISBN 10 : 9780857096272

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Mems for Biomedical Applications Excerpt :

The application of Micro Electro Mechanical Systems (MEMS) in the biomedical field is leading to a new generation of medical devices. MEMS for biomedical applications reviews the wealth of recent research on fabrication technologies and applications of this exciting technology. The book is divided into four parts: Part one introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms. Part two describes applications of MEMS for biomedical sensing and diagnostic applications. MEMS for in vivo sensing and electrical impedance spectroscopy are investigated, along with ultrasonic transducers, and lab-on-chip devices. MEMS for tissue engineering and clinical applications are the focus of part three, which considers cell culture and tissue scaffolding devices, BioMEMS for drug delivery and minimally invasive medical procedures. Finally, part four reviews emerging biomedical applications of MEMS, from implantable neuroprobes and ocular implants to cellular microinjection and hybrid MEMS. With its distinguished editors and international team of expert contributors, MEMS for biomedical applications provides an authoritative review for scientists and manufacturers involved in the design and development of medical devices as well as clinicians using this important technology. Reviews the wealth of recent research on fabrication technologies and applications of Micro Electro Mechanical Systems (MEMS) in the biomedical field Introduces the fundamentals of MEMS for biomedical applications, exploring the microfabrication of polymers and reviewing sensor and actuator mechanisms Considers MEMS for biomedical sensing and diagnostic applications, along with MEMS for in vivo sensing and electrical impedance spectroscopy

Nanomedicine Book

Nanomedicine


  • Author : Thomas J Webster
  • Publisher : Elsevier
  • Release Date : 2012-10-19
  • Genre: Medical
  • Pages : 704
  • ISBN 10 : 9780857096449

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Nanomedicine Excerpt :

Nanotechnology is at the forefront of advances in medicine. Nanomedicine: Technologies and applications provides an important review of this exciting technology and its growing range of applications. After an introduction to nanomedicine, part one discusses key materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings. Part two goes on to review nanomedicine for therapeutics and imaging, before nanomedicine for soft tissue engineering is discussed in part three, including organ regeneration, skin grafts, nanotubes and self-assembled nanomaterials. Finally, nanomedicine for bone and cartilage tissue engineering is the focus of part four, with electrically active biocomposites as smart scaffolds investigated, as is cartilage and bone tissue engineering, regeneration and replacement. With its distinguished editor and international team of expert contributors, Nanomedicine: Technologies and applications is an indispensable guide for all those involved in the research, development and application of this exciting technology, whilst providing a comprehensive introduction for students and academics interested in this field. Provides an important review of nanomedicine technology and its growing range of applications Discusses key nanomedicine materials and their properties, including nanocrystalline metals and alloys, nanoporous gold and hydroxyapatite coatings Reviews nanomedicine for therapeutics and imaging and nanomedicine for soft tissue engineering

Implantable Sensor Systems for Medical Applications Book

Implantable Sensor Systems for Medical Applications


  • Author : Andreas Inmann
  • Publisher : Elsevier
  • Release Date : 2013-01-02
  • Genre: Science
  • Pages : 544
  • ISBN 10 : 9780857096289

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Implantable Sensor Systems for Medical Applications Excerpt :

Implantable sensor systems offer great potential for enhanced medical care and improved quality of life, consequently leading to major investment in this exciting field. Implantable sensor systems for medical applications provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of these devices in a diverse range of medical applications. Part one reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, microassembly, electrode array design and fabrication, and the use of biofuel cells as sustainable power sources. Part two goes on to consider the challenges associated with implantable systems. Biocompatibility, sterilization considerations and the development of active implantable medical devices in a regulated environment are discussed, along with issues regarding data protection and patient privacy in medical sensor networks. Applications of implantable systems are then discussed in part three, beginning with Microelectromechanical systems (MEMS) for in-vivo applications before further exploration of tripolar interfaces for neural recording, sensors for motor neuroprostheses, implantable wireless body area networks and retina implants. With its distinguished editors and international team of expert contributors, Implantable sensor systems for medical applications is a comprehensive guide for all those involved in the design, development and application of these life-changing technologies. Provides a wide-ranging overview of the core technologies, key challenges and main issues related to the development and use of implantable sensor systems in a range of medical applications Reviews the fundamentals of implantable systems, including materials and material-tissue interfaces, packaging and coatings, and microassembly Considers the challenges associated with implantable systems, including biocompatibility and sterilization

Joining and Assembly of Medical Materials and Devices Book

Joining and Assembly of Medical Materials and Devices


  • Author : Y N Zhou
  • Publisher : Elsevier
  • Release Date : 2013-05-31
  • Genre: Technology & Engineering
  • Pages : 574
  • ISBN 10 : 9780857096425

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Joining and Assembly of Medical Materials and Devices Excerpt :

As medical devices become more intricate, with an increasing number of components made from a wide range of materials, it is important that they meet stringent requirements to ensure that they are safe to be implanted and will not be rejected by the human body. Joining and assembly of medical materials and devices provides a comprehensive overview of joining techniques for a range of medical materials and applications. Part one provides an introduction to medical devices and joining methods with further specific chapters on microwelding methods in medical components and the effects of sterilization on medical materials and welded devices. Part two focuses on medical metals and includes chapters on the joining of shape memory alloys, platinum (Pt) alloys and stainless steel wires for implantable medical devices and evaluating the corrosion performance of metal medical device welds. Part three moves on to highlight the joining and assembly of medical plastics and discusses techniques including ultrasonic welding, transmission laser welding and radio frequency (RF)/dielectric welding. Finally, part four discusses the joining and assembly of biomaterial and tissue implants including metal-ceramic joining techniques for orthopaedic applications and tissue adhesives and sealants for surgical applications. Joining and assembly of medical materials and devices is a technical guide for engineers and researchers within the medical industry, professionals requiring an understanding of joining and assembly techniques in a medical setting, and academics interested in this field. Introduces joining methods in medical applications including microwelding and considers the effects of sterilization on the resulting joints and devices Considers the joining, assembly and corrosion performance of medical metals including shape memory alloys, platinum alloys and stainless steel wires Considers the joining and assembly of medical plastics including multiple welding methods, bonding strate