Blanco s Overview of Alpha 1 Antitrypsin Deficiency Book

Blanco s Overview of Alpha 1 Antitrypsin Deficiency


  • Author : Ignacio Blanco
  • Publisher : Academic Press
  • Release Date : 2017-04-28
  • Genre: Medical
  • Pages : 252
  • ISBN 10 : 9780128095416

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Blanco s Overview of Alpha 1 Antitrypsin Deficiency Excerpt :

Blanco’s Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels. Presents the fundamental theoretical and practical aspects of Alpha-1 Antitrypsin Deficiency (AATD) based on scientific evidence Provides evidence to show that AATD is a rarely diagnosed condition, rather than a rare condition Contains current research and future perspectives from Dr. Ignacio Blanco, a worldwide expert in the field of alpha-1 antitrypsin and lung and liver disease associated with the deficiency of this antiprotease Provides resources to current registries and patient associations

Blanco s Overview of Alpha 1 Antitrypsin Deficiency Book

Blanco s Overview of Alpha 1 Antitrypsin Deficiency


  • Author : Ignacio Blanco
  • Publisher : Academic Press
  • Release Date : 2017-05-03
  • Genre: Uncategoriezed
  • Pages : 252
  • ISBN 10 : 012809530X

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Blanco s Overview of Alpha 1 Antitrypsin Deficiency Excerpt :

Blanco's Overview of Alpha-1 Antitrypsin Deficiency: History, Biology, Pathophysiology, Related Diseases, Diagnosis, and Treatment is a robust introduction to topics associated with Alpha-1 Antitrypsin Deficiency (AATD). Included are topics ranging from the history of the disease, biology, pathophysiology, related diseases, including the two major manifestations of the disease (liver disease and lung disease), and diagnosis and treatment. The book addresses the need for the amalgamation of current and novel concepts and practices in the field of AATD. AATD is under-recognized in the medical community and, as a result, it is underdiagnosed. The book provides increased awareness and understanding of the condition to improve diagnosis rates and enhance patient care. This book is an essential tool and reference, beneficial to clinicians who screen and treat AATD patients, as well as research scientists working in the AATD field at junior and senior levels. Presents the fundamental theoretical and practical aspects of Alpha-1 Antitrypsin Deficiency (AATD) based on scientific evidence Provides evidence to show that AATD is a rarely diagnosed condition, rather than a rare condition Contains current research and future perspectives from Dr. Ignacio Blanco, a worldwide expert in the field of alpha-1 antitrypsin and lung and liver disease associated with the deficiency of this antiprotease Provides resources to current registries and patient associations

Alpha 1 antitrypsin Deficiency Book

Alpha 1 antitrypsin Deficiency


  • Author : Noor Kalsheker
  • Publisher : Academic Press
  • Release Date : 2017-06-06
  • Genre: Science
  • Pages : 262
  • ISBN 10 : 9780128039472

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Alpha 1 antitrypsin Deficiency Excerpt :

Alpha-1-antitrypsin Deficiency: Biology, Diagnosis, Clinical Significance, and Emerging Therapies is the authoritative reference on AATD, providing standards for diagnosis, monitoring, treatment and appropriate avenues of research. The book covers the disease from basic biology and epidemiology, to clinical impact, and includes the understanding of the natural history of the disease and the significant advances that have been made in the last 20 years, including the three-dimensional structure of the molecule, its broad biological activity and improved therapeutic options, including replacement therapy and gene therapy. The editors have recruited international experts in the field to contribute evidence-based chapters and insights on future developments in the understanding of this disease. Provides documentation of the variations in clinical presentation and pathology in a single reference Presents new insights by pulling together the advances in the understanding of the structure and function of alpha1-antitrypsin deficiency with the genetic variants that cause the disease Allows for easy reference for the diagnosis of AATD to lead to better therapeutics

COPD Clinical Perspectives Book

COPD Clinical Perspectives


  • Author : Ralph J. Panos
  • Publisher : BoD – Books on Demand
  • Release Date : 2014-07-16
  • Genre: Medical
  • Pages : 210
  • ISBN 10 : 9789535116240

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COPD Clinical Perspectives Excerpt :

Chronic Obstructive Pulmonary Disease (COPD) is an increasingly recognized cause of morbidity and mortality. Over the next 10 years, deaths due to COPD are expected to increase by 30% and, by 2030, COPD is estimated to be the third leading cause of death worldwide. Research into the pathophysiology and management of COPD over the past decade has progressed immensely with greater understanding of the global burden of COPD, its pathophysiology, better understanding of the multisystemic manifestations of COPD, and, most importantly, novel and more effective therapeutic strategies. This volume brings together an international group of experts in COPD to provide in depth reviews of clinical perspectives into COPD. Topics range from the diagnosis of airflow limitation by spirometry; distinguishing COPD from another common obstructive lung disease, asthma; alpha-1-antitrypsin deficiency and opportunities to diagnose this most common hereditary cause of COPD and as a paradigm for the development of novel therapeutics; the overlap syndrome - the concurrence of two epidemic disorders: COPD and obstructive sleep apnea; and pulmonary rehabilitation, one of the most effective treatments for COPD.

Liver Elastography Book

Liver Elastography


  • Author : Sebastian Mueller
  • Publisher : Springer Nature
  • Release Date : 2020-06-02
  • Genre: Medical
  • Pages : 737
  • ISBN 10 : 9783030405427

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Liver Elastography Excerpt :

This is the first comprehensive book on the new elastographic techniques discussing the early assessment of liver fibrosis. The book covers all aspects of measuring liver stiffness starting from the methodology, the molecular basis of liver stiffness elevation up to current clinical algorithms and interpretation. Future directions and novel implications that go beyond diagnosis but are relevant for understanding of liver cirrhosis per se are also discussed in detail. Liver Elastography, is an essential companion for hepatologists and gastroenterologists that provides an overview of its basic principles and gives a detailed account of how to use elastrography in clinical practice.

Alpha 1 Antitrypsin Book

Alpha 1 Antitrypsin


  • Author : Adam Wanner
  • Publisher : Humana Press
  • Release Date : 2015-12-18
  • Genre: Medical
  • Pages : 173
  • ISBN 10 : 9783319234496

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Alpha 1 Antitrypsin Excerpt :

This book offers a comprehensive overview of alpha-1 antitrypsin deficiency, an inherited condition that leads to lung disease in adults and liver disease in adults and children and is associated with chronic obstructive lung disease in adults. While it is a rare condition, the mechanisms underlying the clinical manifestations of this deficiency have been largely clarified. Treatment, however, is available only for the lung disease that arises from the condition, thus necessitating continued research into new and alternative therapeutic solutions. The book discusses the biology of alpha-1 antitrypsin, protein misfolding and polymerization, and diagnosis and treatment of alpha-1 antitrypsin deficiency and its associated diseases. It concludes with a discussion of rare disorders linked to alpha-1 antitrypsin deficiency and the role of healthcare organizations in the treatment of these diseases. Written for pulmonary clinicians and scientists, Alpha-1 Antitrypsin: Role in Health and Disease is a valuable resource that sheds light on this rare disease.

Rare Diseases Epidemiology  Update and Overview Book

Rare Diseases Epidemiology Update and Overview


  • Author : Manuel Posada de la Paz
  • Publisher : Springer
  • Release Date : 2017-12-06
  • Genre: Medical
  • Pages : 667
  • ISBN 10 : 9783319671444

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Rare Diseases Epidemiology Update and Overview Excerpt :

The fields of rare diseases research and orphan products development continue to expand with more products in research and development status. In recent years, the role of the patient advocacy groups has evolved into a research partner with the academic research community and the bio-pharmaceutical industry. Unique approaches to research and development require epidemiological data not previously available to assist in protocol study design and patient recruitment for clinical trials required by regulatory agencies prior to approval for access by patents and practicing physicians.

Liver Disease in Children Book

Liver Disease in Children


  • Author : Frederick J. Suchy
  • Publisher : Cambridge University Press
  • Release Date : 2014-02-20
  • Genre: Medical
  • Pages : 752
  • ISBN 10 : 9781107729094

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Liver Disease in Children Excerpt :

The fourth edition of this authoritative text covers every aspect of liver disease affecting infants, children and adolescents. As in the previous editions, it offers an integrative approach to the science and clinical practice of pediatric hepatology and charts the substantial progress in understanding and treating these diseases. All of the chapters are written by international experts and address the unique pathophysiology, manifestations and management of these disorders. This edition of the landmark text features extended coverage of viral hepatitis, metabolic liver disease, fatty liver disease and liver transplantation, including a new chapter on post-transplant care and outcomes. All of the chapters have been updated to reflect changing epidemiology and recent advances in molecular medicine and genomics. With the continued evolution of pediatric hepatology as a discipline, this text remains an essential reference for all physicians involved in the care of children with liver disease.

Muscle Gene Therapy Book

Muscle Gene Therapy


  • Author : Dongsheng Duan
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-11-26
  • Genre: Medical
  • Pages : 275
  • ISBN 10 : 9781441912077

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Muscle Gene Therapy Excerpt :

Muscle disease represents an important health threat to the general population. There is essentially no cure. Gene therapy holds great promise to correct the genetic defects and eventually achieve full recovery in these diseases. Significant progresses have been made in the field of muscle gene therapy over the last few years. The development of novel gene delivery vectors has substantially enhanced specificity and efficiency of muscle gene delivery. The new knowledge on the immune response to viral vectors has added new insight in overcoming the immune obstacles. Most importantly, the field has finally moved from small experimental animal models to human patients. This book will bring together the leaders in the field of muscle gene transfer to provide an updated overview on the progress of muscle gene therapy. It will also highlight important clinical applications of muscle gene therapy.

Clinical Epidemiology of Chronic Liver Diseases Book

Clinical Epidemiology of Chronic Liver Diseases


  • Author : Robert J. Wong
  • Publisher : Springer
  • Release Date : 2018-10-24
  • Genre: Medical
  • Pages : 349
  • ISBN 10 : 9783319943558

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Clinical Epidemiology of Chronic Liver Diseases Excerpt :

This book emphasizes the clinical epidemiology of chronic liver diseases with a specific focus on the methodology of the discussed studies. The whole spectrum of liver diseases is covered, from chronic hepatitis B and C, to hepatocellular carcinoma, alcoholic and non-alcoholic fatty liver diseases and autoimmune and cholestatic liver diseases. Readers will find the most up-to-date information on clinical epidemiology of hepatology, and will also be able to learn about important methodology and biostatistics information. Each chapter contains a summary table at the end of each chapter that highlights the most relevant landmark studies, their main outcomes and the unique features of the methodology. The book will appeal to both practicing clinicians as well as clinical research investigators. In addition, this would likely be of interest to medical school or public health school students to learn about hepatology epidemiology, but also some specific fundamentals of clinical research and clinical epidemiology.

Principles of Medical Biochemistry E Book Book

Principles of Medical Biochemistry E Book


  • Author : Gerhard Meisenberg
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-09-28
  • Genre: Medical
  • Pages : 600
  • ISBN 10 : 9780323391900

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Principles of Medical Biochemistry E Book Excerpt :

For nearly 30 years, Principles of Medical Biochemistry has integrated medical biochemistry with molecular genetics, cell biology, and genetics to provide complete yet concise coverage that links biochemistry with clinical medicine. The 4th Edition of this award-winning text by Drs. Gerhard Meisenberg and William H. Simmons has been fully updated with new clinical examples, expanded coverage of recent changes in the field, and many new case studies online. A highly visual format helps readers retain complex information, and USMLE-style questions (in print and online) assist with exam preparation. Just the right amount of detail on biochemistry, cell biology, and genetics – in one easy-to-digest textbook. Full-color illustrations and tables throughout help students master challenging concepts more easily. Online case studies serve as a self-assessment and review tool before exams. Online access includes nearly 150 USMLE-style questions in addition to the questions that are in the book. Glossary of technical terms. Clinical Boxes and Clinical Content demonstrate the integration of basic sciences and clinical applications, helping readers make connections between the two. New clinical examples have been added throughout the text.

Pouchitis and Ileal Pouch Disorders Book

Pouchitis and Ileal Pouch Disorders


  • Author : Bo Shen
  • Publisher : Academic Press
  • Release Date : 2018-11-05
  • Genre: Medical
  • Pages : 570
  • ISBN 10 : 9780128096291

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Pouchitis and Ileal Pouch Disorders Excerpt :

Pouchitis and Ileal Pouch Disorders: A Multidisciplinary Approach for Diagnosis and Management provides much needed information on the evolution of pouch surgery, pouch surgery techniques, and surgery-associated complications, including inflammatory, functional, neoplastic, and metabolic complications. The book provides information on the anatomy of the pouch, pathogenesis of pouchitis and other pouch disorders, proper diagnostic modalities, and medical, endoscopic and surgical options for those disorders. The information has been compiled from a panel of national and international leading experts in the field, including basic scientists, gastrointestinal (GI) pathologists, GI radiologists, gastroenterologists, and more. Features never-before-published information and technology from the vast experience of the contributors and editors in diagnosis and medical, endoscopic, and surgical management of pouchitis and other pouch disorders Contains easy to access recommendations from experts Provides access to an accompanying website with videos of endoscopic demonstrations of various configurations of the pouch, endoscopic evaluation of pouch disorders, and endoscopic treatment of pouch strictures, fistula, and anastomotic leaks/sinuses

Essentials of Anesthesia for Infants and Neonates Book

Essentials of Anesthesia for Infants and Neonates


  • Author : Mary Ellen McCann
  • Publisher : Cambridge University Press
  • Release Date : 2018-02-22
  • Genre: Medical
  • Pages : 465
  • ISBN 10 : 9781107069770

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Essentials of Anesthesia for Infants and Neonates Excerpt :

A practical, comprehensive guide to the special needs of infants and neonates undergoing anesthesia.

Advanced Nutrition and Dietetics in Gastroenterology Book

Advanced Nutrition and Dietetics in Gastroenterology


  • Author : Miranda Lomer
  • Publisher : John Wiley & Sons
  • Release Date : 2014-08-25
  • Genre: Medical
  • Pages : 354
  • ISBN 10 : 9780470671320

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Advanced Nutrition and Dietetics in Gastroenterology Excerpt :

Advanced Nutrition and Dietetics in Gastroenterology provides informative and broad-ranging coverage of the relation between nutrition and diet and the gastrointestinal tract. It explores dietary factors involved in causation of a variety of gastrointestinal disorders, as well as the effects on diet and the treatments available. It also provides an overview of anatomy and physiology, measurement and assessment of function, and dietary components relevant to gastrointestinal health. ABOUT THE SERIES Dietary recommendations need to be based on solid evidence, but where can you find this information? The British Dietetic Association and the publishers of the Manual of Dietetic Practice present an essential and authoritative reference series on the evidence base relating to advanced aspects of nutrition and diet in selected clinical specialties. Each book provides a comprehensive and critical review of key literature in its subject. Each covers established areas of understanding, current controversies and areas of future development and investigation, and is oriented around six key themes: •Disease processes, including metabolism, physiology, and genetics •Disease consequences, including morbidity, mortality, nutritional epidemiology and patient perspectives •Nutritional consequences of diseases •Nutritional assessment, drawing on anthropometric, biochemical, clinical, dietary, economic and social approaches •Clinical investigation and management •Nutritional and dietary management •Trustworthy, international in scope, and accessible, Advanced Nutrition and Dietetics is a vital resource for a range of practitioners, researchers and educators in nutrition and dietetics, including dietitians, nutritionists, doctors and specialist nurses.

Endocrine Disrupting Chemicals induced Metabolic Disorders and Treatment Strategies Book

Endocrine Disrupting Chemicals induced Metabolic Disorders and Treatment Strategies


  • Author : Muhammad Sajid Hamid Akash
  • Publisher : Springer Nature
  • Release Date : 2020-08-04
  • Genre: Science
  • Pages : 520
  • ISBN 10 : 9783030459239

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Endocrine Disrupting Chemicals induced Metabolic Disorders and Treatment Strategies Excerpt :

This volume offers a detailed and comprehensive analysis of Endocrine Disrupting Chemicals (EDCs), covering their occurrence, exposure to humans and the mechanisms that lead to the parthogenesis of EDCs-induced metabolic disorders. The book is divided into three parts. Part I describes the physiology of the human endocrine system, with special emphasis on various types of metabolic disorders along with risk factors that are responsible for the development of these disorders. Part II addresses all aspects of EDCs, including their role in the induction of various risk factors that are responsible for the development of metabolic disorders. Part III covers up-to-date environmental regulatory considerations and treatment strategies that have been adopted to cure and prevent EDCs-induced metabolic disorders. This section will primarily appeal to clinicians investigating the causes and treatment of metabolic disorders. The text will also be of interest to students and researchers in the fields of Environmental Pharmacology and Toxicology, Environmental Pollution, Pharmaceutical Biochemistry, Biotechnology, and Drug Metabolism/Pharmacokinetics.