Brucella Melitensis Book

Brucella Melitensis


  • Author : Jangampalli Adi Pradeepkiran
  • Publisher : Academic Press
  • Release Date : 2021-03-03
  • Genre: Medical
  • Pages : 200
  • ISBN 10 : 9780323899970

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Brucella Melitensis Excerpt :

Brucella Miletensis: Identification and Characterization of Potential Drug Targets presents a systematic approach to identifying and characterizing drug targets using bioinformatics. The book shows the potential of bioinformatic tools in the identification of virulence targets in pathogenic bacteria and viruses, in general, and in B. militensis 16M in particular. Chapters identify putative genes as potential drug targets, employ a subtractive genomic approach, consider the virulent genes of this bacteria that negatively affects humans, list twelve potential virulence genes as drug targets, and consider the screening of potential drugs against the bacteria’s virulence genes through molecular modeling, computational screening, drug discovery and molecular docking studies. In addition, the book demonstrates in silico approaches that offer insights into the identification of drug targets in B.melitensis 16M. The title employs a step-by-step approach to understanding drug targets by identifying and characterizing vaccine targets for Brucella melitensis, in silico screening, and the identification of novel drug targets from the total Brucella melitensis proteome. Other sections cover computational modeling and evaluation of the best potential drug targets through comparative modeling, molecular docking, and dynamics simulations of novel drug targets and in silico validation and ADMET analysis for best lead molecules. Covers the identification and characterization of vaccine targets for Brucella melitensis Presents in silico screening and the identification of novel drug targets Gives computational modeling and evaluations for potential drug targets Offers molecular docking and dynamics simulations for novel drug targets Details in silico validation and ADMET analysis for best lead molecules

Animal Brucellosis Book

Animal Brucellosis


  • Author : Klaus Nielsen
  • Publisher : CRC Press
  • Release Date : 2018-01-10
  • Genre: Medical
  • Pages : 463
  • ISBN 10 : 9781351086585

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Animal Brucellosis Excerpt :

This timely publication updates and standardizes currently used diagnostic procedures for this widespread, economically costly livestock disease. It includes state-of-the-art technology, now in limited use, which will replace the conventional methodology in the near future. The volume covers research done on improved diagnostic techniques, vaccines, taxonomy, epidemiology, pathology, and basic immunology. It is an important literature review for those more established in this field and serves as a guide to researchers or diagnosticians becoming involved with this disease.

Updates on Brucellosis Book

Updates on Brucellosis


  • Author : Manal Mohammad Baddour
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-11-19
  • Genre: Medical
  • Pages : 258
  • ISBN 10 : 9789535122111

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Updates on Brucellosis Excerpt :

Brucellosis is a major zoonotic disease that may cause a serious illness in humans and animals. Global prevalence of human brucellosis remains significant. More than half a million new brucellosis cases from 100 countries are reported annually to the World Health Organization (WHO). The majority of these cases are reported in developing countries.In humans, brucellosis (undulant fever, Malta fever) is characterized by an acute bacteremic phase followed by a chronic stage that may extend over many years and may involve many tissues. It is a systemic disease, and many organ systems (nervous system, heart, skeletal system, bone marrow, etc.) may become involved following hematogenous dissemination. Although eradicated in some countries, it remains one of the most economically important zoonosis worldwide as it is responsible for huge economic losses as well as significant human morbidity in endemic areas. Because of the nonspecific clinical manifestations of human brucellosis and the need for prolonged combination therapy with antibiotics that are not routinely prescribed for other infectious diseases, laboratory confirmation of the diagnosis is of paramount importance for adequate patient management. In addition, evidence of brucellosis has serious public health implications because it discloses exposure to a contaminated source (infected animals or their products, unsafe laboratory practices, or a potential biological warfare attack). This book addresses human brucellosis with stress on symptoms including those related to the less recognized disease localizations, risk of exposure, treatment, and prevention. Light is shed on animal brucellosis as it pertains to human exposure. The book also emphasizes on laboratory procedures in culturing and serologic techniques. Epidemiologic surveillance is among this books subjects as well as veterinary control measures.

Animal Disease Thesaurus Book

Animal Disease Thesaurus


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1979
  • Genre: Information storage and retrieval systems
  • Pages : null
  • ISBN 10 : CHI:103584949

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Animal Disease Thesaurus Excerpt :

Animal Disease Book

Animal Disease


  • Author : Edwin Ivan Pilchard
  • Publisher : Unknown
  • Release Date : 1979
  • Genre: Information storage and retrieval systems
  • Pages : 374
  • ISBN 10 : MINN:31951003053871P

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Animal Disease Excerpt :

Brucellosis Book

Brucellosis


  • Author : Edward J. Young
  • Publisher : CRC Press
  • Release Date : 2020-07-24
  • Genre: Medical
  • Pages : 192
  • ISBN 10 : 9781000141900

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Brucellosis Excerpt :

Fourteen brucellosis experts from seven countries discuss the history, epidemiology, microbiology, immunology, diagnosis, treatment, and control of brucellosis in animals and man. Edited by members of the World Health Organization's Expert Committee on Brucellosis, this text is the first comprehensive treatment of the disease since The Nature of Brucellosis by Wesley W. Spink in 1956. Topics reviewed with current references include infection caused by newer species of Brucella, such as B. canis, newer diagnostic techniques, such as radioimmunoassay and ELISA, and newer treatments, such as rifampin and the quinolones. The pathogenesis and pathophysiology of brucellosis is reviewed in depth, correlating the disease in animals with the illness in humans. This volume is extremely useful for clinicians, researchers, and students in medicine, veterinary science, microbiology, immunology, epidemiology, public health, and international health.

Class 2 Transferases Book

Class 2 Transferases


  • Author : Antje Chang
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-06-04
  • Genre: Science
  • Pages : 502
  • ISBN 10 : 9783540857013

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Class 2 Transferases Excerpt :

The Springer Handbook of Enzymes provides concise data on some 5,000 enzymes sufficiently well characterized – and here is the second, updated edition. Their application in analytical, synthetic and biotechnology processes as well as in food industry, and for medicinal treatments is added. Data sheets are arranged in their EC-Number sequence. The new edition reflects considerable progress in enzymology: the total material has more than doubled, and the complete 2nd edition consists of 39 volumes plus Synonym Index. Starting in 2009, all newly classified enzymes are treated in Supplement Volumes.

Advances in Brucella Research and Treatment  2011 Edition Book

Advances in Brucella Research and Treatment 2011 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-01-09
  • Genre: Medical
  • Pages : 19
  • ISBN 10 : 9781464956836

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Advances in Brucella Research and Treatment 2011 Edition Excerpt :

Advances in Brucella Research and Treatment: 2011 Edition is a ScholarlyPaper™ that delivers timely, authoritative, and intensively focused information about Brucellaceae in a compact format. The editors have built Advances in Brucella Research and Treatment: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Brucellaceae in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Brucella Research and Treatment: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Brucella Melitensis Book

Brucella Melitensis


  • Author : J.M. Verger
  • Publisher : Springer
  • Release Date : 1985-08-31
  • Genre: Medical
  • Pages : 270
  • ISBN 10 : 9780898387421

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Brucella Melitensis Excerpt :

A Seminar in the CEC Programme of Coordination of Research on Animal Pathology, held in Brussels at the Commission of the European Communities, 14-15 November 1984. Sponsored by the Commission of the European Communities, Directorate-General for Agriculture, Coordination of Agriculture Research