C Furanosides Book

C Furanosides


  • Author : Peter Goekjian
  • Publisher : Academic Press
  • Release Date : 2017-11-30
  • Genre: Science
  • Pages : 794
  • ISBN 10 : 9780128037898

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C Furanosides Excerpt :

Carbon analogs of carbohydrates, dubbed C-glycosides, have remained an important and interesting class of mimetics, be it in natural product synthesis, for pharmacological applications, as conformational probes, or for biological studies. C-Furanosides: Synthesis and Stereochemistry provides a much-needed overview of synthetic and stereochemical principles for C-furanosides: analogs of a 5-membered ring carbohydrate glycoside (furanoside), in which the anomeric oxygen has been replaced with a carbon. While our understanding of conformational behavior and of stereoselective synthesis in 6-membered ring compounds is quite good, our ability to predict the conformation of 5-membered ring compounds, or to predict the stereochemical outcome of a given reaction, remains anecdotal. Through a comprehensive review of literature approaches to the different C-furanoside stereoisomers, as well as an interpretation of the outcome in terms of a reasonable number of stereochemical models, C-Furanosides: Synthesis and Stereochemistry enables the reader to determine the best approach to a particular C-glycoside compound, and also hopes to provide a certain level of rationalization and predictability for the synthesis of new systems. Provides a comprehensive review of the growing literature in C-furanosides Enables readers to choose the most convenient approach to access a defined target in natural products synthesis or pharmacology and make reasonable predictions for the stereochemical outcome in unpublished cases Explores the various rational models for stereochemical analysis of furanoside reactivity, with a clear distinction made between physical chemical mechanisms and stereochemical models

Index Volume Category 5 Book

Index Volume Category 5


  • Author : Colin J. Drayton
  • Publisher : Georg Thieme Verlag
  • Release Date : 2013-12-11
  • Genre: Science
  • Pages : 1000
  • ISBN 10 : 9783131785817

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Index Volume Category 5 Excerpt :

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in December 2009.

Science of Synthesis  Houben Weyl Methods of Molecular Transformations Vol  37 Book

Science of Synthesis Houben Weyl Methods of Molecular Transformations Vol 37


  • Author : Anonim
  • Publisher : Georg Thieme Verlag
  • Release Date : 2014-05-14
  • Genre: Science
  • Pages : 992
  • ISBN 10 : 9783131783318

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Science of Synthesis Houben Weyl Methods of Molecular Transformations Vol 37 Excerpt :

Science of Synthesis provides a critical review of the synthetic methodology developed from the early 1800s to date for the entire field of organic and organometallic chemistry. As the only resource providing full-text descriptions of organic transformations and synthetic methods as well as experimental procedures, Science of Synthesis is therefore a unique chemical information tool. Over 1000 world-renowned experts have chosen the most important molecular transformations for a class of organic compounds and elaborated on their scope and limitations. The systematic, logical and consistent organization of the synthetic methods for each functional group enables users to quickly find out which methods are useful for a particular synthesis and which are not. Effective and practical experimental procedures can be implemented quickly and easily in the lab.// The content of this e-book was originally published in May 2008.

C Glycoside Synthesis Book

C Glycoside Synthesis


  • Author : Maarten Postema
  • Publisher : CRC Press
  • Release Date : 2020-10-28
  • Genre: Science
  • Pages : 400
  • ISBN 10 : 9781000108552

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C Glycoside Synthesis Excerpt :

This book examines methods particularly well suited for either a- or b-C-glycoside formation. It helps field workers quickly select the best method for synthesizing a particular type of C-glycoside. The use of C-glycosides as synthons in natural product synthesis is also addressed.

The Chemistry of C Glycosides Book

The Chemistry of C Glycosides


  • Author : D.E. Levy
  • Publisher : Elsevier
  • Release Date : 1995-12-21
  • Genre: Science
  • Pages : 290
  • ISBN 10 : 9780080529011

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The Chemistry of C Glycosides Excerpt :

In recent years C-glycoside chemistry has been one of the main topics in carbohydrate chemistry, not only because of the synthetic challenges posed, but also because C-glycosides have the potential to serve as carbohydrate analogues resistant to metabolic processes. Consequently, this class of compounds is currently receiving much interest as a potential source of therapeutic agents for clinical use. This book provides a broad coverage of the various synthetic methods available for the preparation of C-glycosides, and illustrates the interesting breadth of connections between carbohydrate chemistry and modern general synthetic organic chemistry by including topics such as transition-metal catalysis, radical chemistry, cycloaddition and rearrangement processes. In addition, in the final chapter of the book, the syntheses of C-di and trisaccharides reported through 1994 are reviewed. This well organised account of the synthetic chemistry in this field will prove to be very valuable to a wide range of researchers and advanced students, both as an introduction to the topic and for reference.

Science of Synthesis Book

Science of Synthesis


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2012
  • Genre: Chemistry, Organic
  • Pages : null
  • ISBN 10 : STANFORD:36105132419131

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Science of Synthesis Excerpt :

The Organic Chemistry of Sugars Book
Score: 4
From 1 Ratings

The Organic Chemistry of Sugars


  • Author : Daniel E. Levy
  • Publisher : CRC Press
  • Release Date : 2005-09-21
  • Genre: Medical
  • Pages : 904
  • ISBN 10 : 9781420027952

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The Organic Chemistry of Sugars Excerpt :

Intrigued as much by its complex nature as by its outsider status in traditional organic chemistry, the editors of The Organic Chemistry of Sugars compile a groundbreaking resource in carbohydrate chemistry that illustrates the ease at which sugars can be manipulated in a variety of organic reactions. Each chapter contains numerous examples demonst

Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience Book

Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience


  • Author : Zbigniew J. Witczak
  • Publisher : John Wiley & Sons
  • Release Date : 2016-01-07
  • Genre: Science
  • Pages : 368
  • ISBN 10 : 9781119044239

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Domino and Intramolecular Rearrangement Reactions as Advanced Synthetic Methods in Glycoscience Excerpt :

The book consists of a brief introduction, a foreward provided byprofessor Danishefsky of Columbia University, and about 14 –16 chapters, each written by one or two eminent scholars/authorsdescribing their recent research in the area of either dominoreactions or intramolecular rearrangements in carbohydratechemistry. Three or four chapters will be reviews. The domino (cascade, tandem)reactions are always intramolecular. They are usually very fast,clean and offer highly complex structures in a one pot process.Intramolecular rearrangements offer very similar advantages andoften lead to highly complex products as well. Although manyrecently isolated carbohydrates fulfill various sophisticatedfunctions, their structures are often very complex. The editorscover the broadest scope of novel methodologies possible. All thesynthetic and application aspects of domino/cascade reactions areexplored in this book. A second theme that will be covered isintramolecular rearrangement, which is also fast, stereoselective,and often constitutes one or more steps of domino /cascade process.Selected examples of intramolecular rearrangements are presented.Together, both processes offer an elegant and convenient approach to the synthesis of many complex molecules,which are normally difficult to synthesize via alternative routes.It appears that domino and intramolecular rearrangements areideally suited to synthesize certain specific modifiedmonosaccharides. What is particularly important is that bothprocesses are intermolecular and almost always yield products withvery well-defined stereochemistry. This high definition isabsolutely crucial when synthesizing advanced, modified mono andoligosaccharides. The choice of contributors reflects anemphasis on both therapeutic and pharmacological aspects of carbohydratechemistry.

Glycoscience  Chemistry and Chemical Biology I   III Book

Glycoscience Chemistry and Chemical Biology I III


  • Author : Bertram O. Fraser-Reid
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 2872
  • ISBN 10 : 9783642568749

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Glycoscience Chemistry and Chemical Biology I III Excerpt :

Glycostructures play a highly diverse and crucial role in a myriad of organisms and systems in biology, physiology, medicine, and bioengineering and technology. Only in recent years have the tools been developed to partly understand the highly complex functions and chemistry behind them. In this set the editors present up-to-date information on glycostructures, their chemistry and chemical biology, in the form of a comprehensive survey. The text is accompanied by over 2000 figures, chemical structures and reaction schemes and more than 9000 references. The accompanying CD-ROM enables, besides text searches, searches for structures, schemes, and other information.

Carbohydrate Chemistry Book

Carbohydrate Chemistry


  • Author : R J Ferrier
  • Publisher : Royal Society of Chemistry
  • Release Date : 2007-10-31
  • Genre: Science
  • Pages : 430
  • ISBN 10 : 9781847553119

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Carbohydrate Chemistry Excerpt :

Carbohydrate Chemistry provides review coverage of all publications relevant to the chemistry of monosaccharides and oligosaccharides in a given year. The amount of research in this field appearing in the organic chemical literature is increasing because of the enhanced importance of the subject, especially in areas of medicinal chemistry and biology. In no part of the field is this more apparent than in the synthesis of oligosaccharides required by scientists working in glycobiology. Clycomedicinal chemistry and its reliance on carbohydrate synthesis is now very well established, for example, by the preparation of specific carbohydrate- based antigens, especially cancer-specific oligosaccharides and glycoconjugates. Coverage of topics such as nucleosides, amino-sugars, alditols and cyclitols also covers much research of relevance to biological and medicinal chemistry. Each volume of the series brings together references to all published work in given areas of the subject and serves as a comprehensive database for the active research chemist Specialist Periodical Reports provide systematic and detailed review coverage in major areas of chemical research. Compiled by teams of leading authorities in the relevant subject areas, the series creates a unique service for the active research chemist, with regular, in-depth accounts of progress in particular fields of chemistry. Subject coverage within different volumes of a given title is similar and publication is on an annual or biennial basis.

Recent Trends in Carbohydrate Chemistry Book

Recent Trends in Carbohydrate Chemistry


  • Author : Amélia Pilar Rauter
  • Publisher : Elsevier
  • Release Date : 2020-04-27
  • Genre: Science
  • Pages : 492
  • ISBN 10 : 9780128174685

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Recent Trends in Carbohydrate Chemistry Excerpt :

Carbohydrate chemistry provides access to carbohydrate-based natural products and synthetic molecules as useful biologically active structures relevant to many health care and disease-related biological processes. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates covers green and sustainable reactions, organometallic carbohydrate chemistry, synthesis of glycomimetics, multicomponent reactions, and chemical transformations leading to molecular diversity based on carbohydrates. These include inhibitors of glycogen phosphorylase, which are relevant in controlling type 2 diabetes and sugar sulfates. Polysaccharides, which are commonly modified chemically, are also examined with contributions covering polysaccharide synthesis and modification of polysaccharides to obtain new structures and properties. Recent Trends in Carbohydrate Chemistry: Synthesis, Structure, and Function of Carbohydrates is ideal for researchers working as synthetic organic chemists, and for those interested in biomolecular chemistry, green chemistry, organometallic chemistry, and material chemistry in academia as well as in industry Demonstrates the importance of carbohydrate chemistry as green and sustainable chemistry Details monosaccharide syntheses and transformations toward biologically active small molecular entities Provides the most recent findings on polysaccharide synthesis and bioapplications

Carbohydrate Chemistry Volume 45 Book

Carbohydrate Chemistry Volume 45


  • Author : Yves Queneau
  • Publisher : Royal Society of Chemistry
  • Release Date : 2021-12-22
  • Genre: Science
  • Pages : 664
  • ISBN 10 : 9781839163906

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Carbohydrate Chemistry Volume 45 Excerpt :

Carbohydrate Chemistry is an invaluable volume demonstrating the interdisciplinary nature of modern carbohydrate research and containing analysed, evaluated and distilled information on the latest research in the area.

Carbohydrate Chemistry Book

Carbohydrate Chemistry


  • Author : Amelia Pilar Rauter
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-12-12
  • Genre: Science
  • Pages : 264
  • ISBN 10 : 9781788014090

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Carbohydrate Chemistry Excerpt :

Demonstrating the interdisciplinary nature of modern glycosciences, this volume covers research in the fields of polysaccharides and small carbohydrates from the synthetic and structural viewpoints, with applications ranging from biology to the bioeconomy. Key aspects of the synthesis and properties of imino disaccharides and regioselective glycosylation reactions are reviewed, glycosyltransferase inhibitors are shown to be potential future therapeutic agents, protein-carbohydrate interactions in plant cell-wall biodegradation are targeted by the use of glycan microarrays, biological properties of polysaccharidic microbial surface antigens are discussed with respect to their intimate structure, and contributions on carbohydrate-based hydrogelators, green/blue sugar-based surfactants and carbohydrate-based green solvents illustrate the modern design of tomorrow’s chemicals. With the increase in volume, velocity and variety of information, researchers can find it difficult to keep up to date with the literature in their field and this book remains a valuable addition to any researcher’s library.

Carbohydrate Chemistry Book

Carbohydrate Chemistry


  • Author : Yves Queneau
  • Publisher : Royal Society of Chemistry
  • Release Date : 2014-03-25
  • Genre: Reference
  • Pages : 645
  • ISBN 10 : 9781849739658

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Carbohydrate Chemistry Excerpt :

Volume 40 of Carbohydrate Chemistry: Chemical and Biological Approaches demonstrates the importance of the glycosciences for innovation and societal progress. Carbohydrates are molecules with essential roles in biology and also serve as renewable resources for the generation of new chemicals and materials. Honouring Professor Andr� Lubineau's memory, this volume resembles a special collection of contributions in the fields of green and low-carbon chemistry, innovative synthetic methodology and design of carbohydrate architectures for medicinal and biological chemistry. Green methodology is illustrated by accounts on the industrial development of water-promoted reactions (C-glycosylation, cycloadditions) and the design of green processes and synthons towards sugar-based surfactants and materials. The especially challenging transformations at the anomeric center are presented in several contributions on glycosylation methodologies using iron or gold catalysis, electrochemical or enzymatic (thio)glycosylation, exo-glycal chemistry and bioengineering of carbohydrate synthases. Then, synthesis and structure of multivalent and supramolecular oligosaccharide architectures are discussed and related to their physical properties and application potential, e.g. for deepening our understanding of biological processes, such as enzymatic pathways or bacterial adhesion, and design of antibacterial, antifungal and innovative anticancer vaccines or drugs.