Cellular and Molecular Pathobiology of Cardiovascular Disease Book

Cellular and Molecular Pathobiology of Cardiovascular Disease


  • Author : Monte Willis
  • Publisher : Academic Press
  • Release Date : 2013-12-23
  • Genre: Science
  • Pages : 338
  • ISBN 10 : 9780124055254

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Cellular and Molecular Pathobiology of Cardiovascular Disease Excerpt :

Cellular and Molecular Pathobiology of Cardiovascular Disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. This book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for PhD trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. No other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. The text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. It is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. Explains how to identify cardiovascular pathologies and compare with normal physiology to aid research Gives concise explanations of key issues and background reading suggestions Covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Cardiovascular Pathology Book

Cardiovascular Pathology


  • Author : L. Maximilian Buja
  • Publisher : Academic Press
  • Release Date : 2015-11-11
  • Genre: Science
  • Pages : 830
  • ISBN 10 : 9780128004593

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Cardiovascular Pathology Excerpt :

Cardiovascular Pathology, Fourth Edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. This updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. Congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. Each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. New chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. Each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. Customers buy the Print + Electronic product together! Serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine Offers new organization of each chapter to enable uniformity for learning and reference: Definition, Epidemiology, Clinical Presentation, Pathogenesis/Genetics, Light and Electron Microscopy/Immunohistochemistry, Differential Diagnosis, Treatment and Potential Complications Features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system Contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation

Endocrinology of the Heart in Health and Disease Book

Endocrinology of the Heart in Health and Disease


  • Author : Jonathan C. Schisler
  • Publisher : Academic Press
  • Release Date : 2016-10-19
  • Genre: Medical
  • Pages : 378
  • ISBN 10 : 9780128031124

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Endocrinology of the Heart in Health and Disease Excerpt :

Endocrinology of the Heart in Health and Disease: Integrated, Cellular, and Molecular Endocrinology of the Heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. The book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. Additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. Significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. The book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. It is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and PhD programs (e.g. Pathology, Physiology, Genetics, Pharmacology, Molecular Biology, and Cell Biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. Develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease Explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically Offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Pathophysiology and Pharmacotherapy of Cardiovascular Disease Book

Pathophysiology and Pharmacotherapy of Cardiovascular Disease


  • Author : Gowraganahalli Jagadeesh
  • Publisher : Springer
  • Release Date : 2015-05-06
  • Genre: Medical
  • Pages : 1342
  • ISBN 10 : 9783319159614

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Pathophysiology and Pharmacotherapy of Cardiovascular Disease Excerpt :

The present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. It provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. In addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.

Molecular Pathology Book

Molecular Pathology


  • Author : William B. Coleman
  • Publisher : Academic Press
  • Release Date : 2017-11-09
  • Genre: Medical
  • Pages : 802
  • ISBN 10 : 9780128027875

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Molecular Pathology Excerpt :

As the molecular basis of human disease becomes better characterized, and the implications for understanding the molecular basis of disease becomes realized through improved diagnostics and treatment, Molecular Pathology, Second Edition stands out as the most comprehensive textbook where molecular mechanisms represent the focus. It is uniquely concerned with the molecular basis of major human diseases and disease processes, presented in the context of traditional pathology, with implications for translational molecular medicine. The Second Edition of Molecular Pathology has been thoroughly updated to reflect seven years of exponential changes in the fields of genetics, molecular, and cell biology which molecular pathology translates in the practice of molecular medicine. The textbook is intended to serve as a multi-use textbook that would be appropriate as a classroom teaching tool for biomedical graduate students, medical students, allied health students, and others (such as advanced undergraduates). Further, this textbook will be valuable for pathology residents and other postdoctoral fellows that desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. In addition, this textbook is useful as a reference book for practicing basic scientists and physician scientists that perform disease-related basic science and translational research, who require a ready information resource on the molecular basis of various human diseases and disease states. Explores the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease Explains the practice of “molecular medicine and the translational aspects of molecular pathology Teaches from the perspective of “integrative systems biology Enhanced digital version included with purchase

Essential Concepts in Molecular Pathology Book

Essential Concepts in Molecular Pathology


  • Author : William B. Coleman
  • Publisher : Academic Press
  • Release Date : 2010-02-16
  • Genre: Science
  • Pages : 462
  • ISBN 10 : 008092218X

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Essential Concepts in Molecular Pathology Excerpt :

This streamlined "essential" version of the Molecular Pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. It is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). It is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). Further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. Offers an essential introduction to molecular genetics and the "molecular" aspects of human disease Teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease In-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "Traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine Each chapter ends with Key Summary Points and Suggested Readings

Hypoxia and Anoxia Book

Hypoxia and Anoxia


  • Author : Kusal Das
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-12-12
  • Genre: Medical
  • Pages : 144
  • ISBN 10 : 9781789848281

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Hypoxia and Anoxia Excerpt :

The molecular deprivation of oxygen is manifested by hypoxia, a deficiency of oxygen and anoxia, or the absence of oxygen supply to the tissues. This book entitled Hypoxia and Anoxia will cover a broad range of understanding on hypoxia and anoxia from molecular mechanisms to pathophysiology. Hypoxia and anoxia stimulate multiple systems through specific cell signal transduction pathways and regulate several transcriptional factors like HIF-1, REST to encode genes for VEGF, Epo, etc. This book will also highlight different types of hypoxia and anoxia along with their impact on apoptosis, cardiovascular pathophysiology, and glucose regulatory mechanisms. This book will be a ready reckoner to give a deep understanding of the oxygen-sensing environment in vivo for researchers, academicians, and clinicians throughout the world.

Pathology of Heart Disease in the Fetus  Infant and Child Book

Pathology of Heart Disease in the Fetus Infant and Child


  • Author : Michael T. Ashworth
  • Publisher : Cambridge University Press
  • Release Date : 2019-10-31
  • Genre: Medical
  • Pages : 500
  • ISBN 10 : 9781107116283

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Pathology of Heart Disease in the Fetus Infant and Child Excerpt :

Clearly presents the pathology of heart disease from fetus to adolescence, integrating histology and macroscopy with effects of treatment.

Pathophysiology of Cardiovascular Disease Book

Pathophysiology of Cardiovascular Disease


  • Author : Naranjan S. Dhalla
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Medical
  • Pages : 648
  • ISBN 10 : 9781461504535

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Pathophysiology of Cardiovascular Disease Excerpt :

Pathophysiology of Cardiovascular Disease has been divided into four sections that focus on heart dysfunction and its associated characteristics (hypertrophy, cardiomyopathy and failure); vascular dysfunction and disease; ischemic heart disease; and novel therapeutic interventions. This volume is a compendium of different approaches to understanding cardiovascular disease and identifying the proteins, pathways and processes that impact it.

Cardiovascular Risk Factors in Pathology Book

Cardiovascular Risk Factors in Pathology


  • Author : Alaeddin Abukabda
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-04-21
  • Genre: Medical
  • Pages : 142
  • ISBN 10 : 9781838819491

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Cardiovascular Risk Factors in Pathology Excerpt :

This book provides a broad overview of the molecular mechanisms associated with relevant and significant cardiovascular conditions that continue to plague humanity. It also discusses potential and promising therapeutic avenues targeted at addressing these conditions. The overarching goal of this multifaceted work is to entice future and current members of the scientific community to direct their endeavors towards improving our current knowledge of cardiovascular disease conditions and curb their impact on our everyday lives.

Diagnostic Molecular Pathology Book

Diagnostic Molecular Pathology


  • Author : William B. Coleman
  • Publisher : Academic Press
  • Release Date : 2016-10-05
  • Genre: Science
  • Pages : 582
  • ISBN 10 : 9780128011577

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Diagnostic Molecular Pathology Excerpt :

Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). In each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. Sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. The book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). In addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. Diagnostic Molecular Pathology: A Guide to Applied Molecular Testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. Readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. Focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient Explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease Features an ancillary website with self-testing exercises where decision trees can

Heart Physiology and Pathophysiology Book

Heart Physiology and Pathophysiology


  • Author : Yoshihisa Kurachi
  • Publisher : Elsevier
  • Release Date : 2000-10-09
  • Genre: Science
  • Pages : 1261
  • ISBN 10 : 9780080533889

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Heart Physiology and Pathophysiology Excerpt :

Heart Physiology and Pathophysiology, 4E, provides the foundation for the scientific understanding of heart function and dysfunction, and bridges the gap between basic cardiovascular science and clinical cardiology. This comprehensive text covers all the important aspects of the heart and vascular system. The most important and relevant disorders are presented, with emphasis on the mechanisms involved. The first three editions of this book developed a reputation as the leading reference in cardiovascular science for researchers and academic cardiologists. This recent edition has been updated, expanded, and includes a number of new contributors. It has also been remodeled to expand its usage as a text reference for cardiology residents, practicing cardiologists, and graduate students. Key Features * The most comprehensive book available on this topic * Clear, concise, and complete coverage of all important aspects of cardiovascular physiology/pathophysiology * Completely updated version of the foremost reference on cardiovascular science, including new information on pathophysiology and electrophysiology * Useful tool in bridging the gap between basic science, pathophysiology, and clinical cardiology

Cardiovascular Pathology Book

Cardiovascular Pathology


  • Author : L. Maximilian L. Buja
  • Publisher : Academic Press
  • Release Date : 2022-01-15
  • Genre: Science
  • Pages : 1026
  • ISBN 10 : 0128222247

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Cardiovascular Pathology Excerpt :

Cardiovascular Pathology, Fifth Edition provides a comprehensive and contemporary treatise on the pathology of cardiovascular diseases, combining presentations of detailed pathology of cardiovascular diseases coupled with discussions of contemporary insights into the etiology and pathogenesis of these conditions. Twenty-two chapters cover general topics, including cardiovascular genetics, heart failure, and transplantation, and specific congenital and acquired cardiovascular diseases, therapeutic interventions, and forensic aspects. New chapters address the scope of practice and training in cardiovascular pathology, with a focus on major diagnostic approaches used in contemporary practice and research in cardiovascular pathology, and a perspective on the field of cardiovascular regenerative medicine linked to the basic pathobiology of cell-based therapy. Cardiovascular Pathology provides a unique combination of details of pathological anatomy essential for pathologists involved in the evaluation of cardiovascular specimens and cardiovascular diseases, and is an excellent reference for anyone interested in the natural history and therapeutic advances in the cardiovascular field. The book's content makes clear that cardiovascular pathologists will continue to have an important role in defining the impact of new therapeutic approaches on the outcomes of patients with cardiovascular diseases. Expanded coverage of diagnostic guidelines, standards and normal values A summary of cardiac catheterization laboratory and diagnostic imaging tests to guide pathologists in clinicopathological correlation Contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows in pathology, cardiology, cardiac surgery, and internal medicine In-depth coverage of all major cardiovascular disease processes, including atherosclerosis and other diseases of large vessels, systemic and pulmonary blood vessels, ischemic heart

Essential Concepts in Molecular Pathology Book

Essential Concepts in Molecular Pathology


  • Author : William B. Coleman
  • Publisher : Academic Press
  • Release Date : 2019-11-23
  • Genre: Medical
  • Pages : 634
  • ISBN 10 : 9780128132586

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Essential Concepts in Molecular Pathology Excerpt :

Essential Concepts in Molecular Pathology, Second Edition, offers an introduction to molecular genetics and the "molecular" aspects of human disease. The book illustrates how pathologists harness their understanding of these entities to develop new diagnostics and treatments for various human diseases. This new edition offers pathology, genetics residents, and molecular pathology fellows an advanced understanding of the molecular mechanisms of disease that goes beyond what they learned in medical and graduate school. By bridging molecular concepts of pathogenesis to the clinical expression of disease in cell, tissue and organ, this fully updated, introductory reference provides the background necessary for an understanding of today’s advances in pathology and medicine. Explains the practice of "molecular medicine" and the translational aspects of molecular pathology, including molecular diagnostics, molecular assessment and personalized medicine Orients non-pathologists on what pathologists look for and how they interpret their observational findings based on histopathology Provides the reader with what is missing from most targeted introductions to pathology—the cell biology behind pathophysiology

Cardiovascular Disease Book

Cardiovascular Disease


  • Author : Gaetano Santulli
  • Publisher : MDPI
  • Release Date : 2021-04-30
  • Genre: Medical
  • Pages : 445
  • ISBN 10 : 9783036509921

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Cardiovascular Disease Excerpt :

According to the most updated epidemiological studies, cardiovascular disease remains a leading cause of death; in fact, despite substantial advances in the care of patients, the incidence of cardiovascular disorders continues to increase. Therefore, the search for novel mechanisms and therapeutics is desperately needed, and translational studies represent the best strategy to uncover novel therapeutic targets, reduce mortality, and improve the quality of life. This book gathers original articles and systematic reviews that have both a strong basic research background and clear translational potential. All the studies have been peer reviewed by at least two experts in the field. These contributions provide an updated systematic overview that examines, in detail, the mechanisms of the main cardiovascular and metabolic disorders, including ischemic and non-ischemic heart failure, hypertension, thromboembolism, atherosclerosis, stroke, diabetes mellitus, dyslipidemia, metabolic syndrome, valvulopathies, peripheral artery disease. In the final chapter, the functional role of the endothelium in the systemic manifestations of COVID-19 is described.