Clinical Bioenergetics

Clinical Bioenergetics

• Author : Sergej M. Ostojic
• Publisher : Academic Press
• Release Date : 2020-11-12
• Genre: Science
• Pages : 716
• ISBN 10 : 9780128227725

Clinical Bioenergetics: From Pathophysiology to Clinical Translation provides recent developments surrounding the etiology and pathophysiology of inherited and acquired energy-delated disorders. Across 40 chapters, world leaders in bioenergetics and mitochondrial medicine discuss novel methodologies designed to identify deficiencies in cellular bioenergetics, as well as the safety and efficacy of emerging management strategies to address poor cellular bioenergetics. Topics discussed include the omics landscape of impaired mitochondrial bioenergetics, hormones, tissue bioenergetics and metabolism in humans. Disease-specific case studies, modes of analysis in clinical bioenergetics, and therapeutic opportunities for impaired bioenergetics, addressing both known treatment pathways and future directions for research, are discussed in-depth. Diseases and Disorders examined include brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among others. Provides a thorough discussion of foundational aspects of bioenergetics and disease, modes of analysis, and treatments for impaired bioenergetics Discusses the role of bioenergetics and treatment pathways in brain injury, chronic fatigue syndrome, psychiatric disorders, pulmonary fibrosis, neurodegenerative disorders, heart failure, chronic kidney disease, obesity, and insulin resistance, among other diseases and disorders Features chapter contributions from international leaders in translational bioenergetics research and clinical practice

Clinical Bioenergetics

• Author : Michael Galitzer
• Publisher : Unknown
• Release Date : 1994-06-01
• Genre: Uncategoriezed
• Pages : 36
• ISBN 10 : 1885325002

Bioenergetics

• Author : David G. Nicholls
• Publisher : Academic Press
• Release Date : 2013-05-20
• Genre: Science
• Pages : 434
• ISBN 10 : 9780123884312

Extensively revised, the fourth edition of this highly successful book takes into account the many newly determined protein structures that provide molecular insight into chemiosmotic energy transduction, as well as reviewing the explosive advances in 'mitochondrial physiology'-the role of the mitochondria in the life and death of the cell. Covering mitochondria, bacteria and chloroplasts, the fourth edition of Bioenergetics provides a clear and comprehensive account of the chemiosmotic theory and its many applications. The figures have been carefully designed to be memorable and to convey the key functional and mechanistic information. Written for students and researchers alike, Bioenergetics is the most well-known, current and respected text on chemiosmotic theory and membrane bioenergetics available. BMA Medical Book Awards 2014-Highly Commended, Basic and Clinical Sciences,2014,British Medical Association Chapters are now divided between three interlocking sections: basic principles, structures and mechanisms, and mitochondrial physiology. Covers new advances in the structure and mechanism of key bioenergetic proteins, including complex I of the respiratory chain and transport proteins. Details cellular bioenergetics, mitochondrial cell biology and signal transduction, and the roles of mitochondria in physiology, disease and aging. Offers readers clear, visual representation of structural concepts through full colour figures throughout the book.

Frontiers of Cellular Bioenergetics

• Author : S. Papa
• Publisher : Springer Science & Business Media
• Release Date : 2012-12-06
• Genre: Science
• Pages : 801
• ISBN 10 : 9781461548430

1. The Mitochondrial and Bacterial Respiratory Chains: From MacMunn and Keilin to Current Concepts; P. Nicholls. 2. The Mitochondrial Enzymes of Oxidative Phosphorylation; Y. Hatefi. 3. Proton Pumps of Respiratory Chain Enzymes; S. Papa, et al. 4. Uncoupling of Respiration and Phosphorylation; V.P. Skulachev. 5. Crystallization, Structure, and Possible Mechanism of Action of Cytochrome c Oxidase from the Soil Bacterium Paracoccus denitrificans; M. Hartmut, et al. 6. The Structure of Crystalline Bovine Heart Cytochrome c Oxidase; S. Yoshikawa, et al. 7. Electron and Proton Transfer in.

Bioenergetics Primer for Exercise Science

• Author : Jie Kang
• Publisher : Human Kinetics
• Release Date : 2008
• Genre: Bioenergetics
• Pages : 232
• ISBN 10 : 0736062416

"More in-depth than cursory discussions found in exercise physiology texts and more practical and accessible than dedicated bioenergetics texts, Bioenergetics Primer for Exercise Science encompasses all the up-to-date research and information regarding human bioenergetics and energy metabolism. It offers both students and professionals a depth of knowledge that will inform their further study, research, and profession."--Jacket.

Membrane Bioenergetics

• Author : Vladimir Petrovich Skulachev
• Publisher : Springer
• Release Date : 1988
• Genre: Bioenergetics
• Pages : 464
• ISBN 10 : UOM:39015012642990

Bioenergetic Analysis

• Author : Iiba
• Publisher : Psychosozial-Verlag
• Release Date : 2012-02
• Genre: Uncategoriezed
• Pages : 130
• ISBN 10 : 383792159X

Bioenergetic Analysis, the Clinical journal of the IIBA is published annually and is distributed to all members of the international organization. Its purpose is to further elaborate theoretical and scientific concepts and to make links to enhance communication and broaden our connection with other schools of therapy, as well as with academic psychology, medicine, and other psychosomatic schools of thought. The journal publishes reports on empirical research, theoretical papers, and case studies. Some local IIBA societies produce journals in their native languages. This journal has been published in English since 1985, making it the oldest journal for the IIBA. The present issue contains three papers on the implications of neuroscience on Bioenergetics; one paper on pre-oedipal transferences; and one paper on infant research and Bioenergetics. There is a poem, as well as a book review on a new bioenergetic techniques textbook. Again, the abstracts of the original papers are all translated into six languages.

Research Awards Index

• Author : Anonim
• Publisher : Unknown
• Release Date : 1989
• Genre: Medicine
• Pages : null
• ISBN 10 : UOM:39015014022589

Creatine and Creatine Phosphate

• Author : Michael W. Conway
• Publisher : Academic Press
• Release Date : 1996-09-20
• Genre: Science
• Pages : 242
• ISBN 10 : 0080530087

Creatine and Creatine Phosphate: Scientific and Clinical Perspectives is an up-to-date summary of both the scientific and medical aspects of creatine and creatine phosphate metabolism and therapy. It covers in detail the basic biochemistry, bioenergetics and biophysics of these agents with particular emphasis on their role on the cardiovascular and muscle systems. Modern in vivo myocardial and skeletal muscle measurements are outlined, and the importance of the molecules in cardiovascular medicine, sport science and cardiac surgery are highlighted. This book is designed for those interested in the basic scientific background to creatine and creatine phosphate, and also for physicians treating or studying heart and vascular disease. The book will also be vital for sports scientists who wish to acquire a comprehensive knowledge of the molecule which is currently being promoted for performance and exercise programmes.

Coenzyme Q

• Author : Giorgio Lenaz
• Publisher : John Wiley & Sons
• Release Date : 1985
• Genre: Bioenergetics
• Pages : 536
• ISBN 10 : MINN:319510002250349

It is becoming increasingly apparent that Coenzyme Q (Ubiquinone) is a major component of the electron transfer chains within aerobic micro-oganisms, photo-synthetic micro-organisms and mitochondria of eukaryotes. In particular, the proposal by Nobel laureate, Peter Mitchell, that Coenzyme Q possibly acts as a proton translocator within a proton motive Q-cycle, thus establishing an electrochemical membrane potential which in turn drives ATP synthesis, has received wide attention. This exhaustive, inter-disciplinary study discusses Ubiquinone's chemical and physical properties, metabolism, and function in different organisms.

The Charnoly Body

• Author : Sushil Sharma
• Publisher : CRC Press
• Release Date : 2019-01-30
• Genre: Medical
• Pages : 388
• ISBN 10 : 9781351366717

Diversified physicochemical injuries trigger Charnoly body (CB) formation as pleomorphic, electron-dense, multi-lamellar stacks of nonfunctional mitochondrial membranes in the most vulnerable cell. Free radicals induce downregulation of mitochondrial DNA, microRNA, AgNOR, and epigenetics to trigger CB molecular pathogenesis. CB is eliminated by energy (ATP)-driven lysosome-dependent charnolophagy as a basic molecular mechanism of intracellular detoxification to prevent acute and chronic diseases. Accumulation of CB at the junction of axon hillock and charnolosome (CS) at the synapses causes cognitive impairments; whereas, nonspecific induction of CB causes GIT stress, myelosuppression, alopecia, neurotoxicity, cardiotoxicity, and infertility in multidrug-resistant malignancies. Hence, stem cell-specific CB, charnolophagy, and CS agonists/antagonists are introduced as novel charnolopharmacotherapeutics for the successful treatment of cardiovascular diseases, neurodegenerative diseases, infectious diseases, drug addiction, and cancer. Nanoparticles to improve drug delivery, CS exocytosis, and disease-specific spatiotemporal charnolosomics employing correlative and combinatorial bioinformatics boost mitochondrial bioenergetics through balanced diet, exercise, and antioxidants. The book will be of interest to medical scientists and practitioners.

Cellular Bioenergetics Role of Coupled Creatine Kinases

• Author : Valdur A. Saks
• Publisher : Springer Science & Business Media
• Release Date : 2012-12-06
• Genre: Science
• Pages : 346
• ISBN 10 : 9781461526124

Most of the information on the functional role, structure and molecular biology of creatine kinase is scattered in several hundreds of publications. The editors of this volume invited all authors who are most active at present in experimental research on creatine kinases to summarize their work and make the information easily available to a wider scientific audience, especially to young investigators who are entering this field. Since the functional role of coupled creatine kinases is directly related to the phenomenon of compartmentation and structural organization of metabolic networks, we also invited experts in the related areas to contribute to the volume. Almost all invited authors responded enthusiastically and the results of this collective work are presented here. For biochemists, biophysicists, physiologists, and medical research workers.

Metabolic and Bioenergetic Drivers of Neurodegenerative Disease Neurodegenerative Disease Research and Commonalities with Metabolic Diseases

• Author : Anonim
• Publisher : Academic Press
• Release Date : 2020-08-10
• Genre: Medical
• Pages : 452
• ISBN 10 : 9780128201268

Metabolic Drivers and Bioenergetic Components of Neurodegenerative Disease summarizes recent developments in intervention trials in neurodegenerative diseases, particularly Alzheimer’s and Parkinson’s, as well as increasing evidence for the overlap between drivers of metabolic and neurodegenerative disease that impact mitochondrial function and bioenergetics, and subsequently cellular function and pathophysiology. Topics covered include Brain Glucose and Ketone Utilization in Brain Ageing and Neurodegenerative Diseases; the Mitochondrial Hypothesis: Dysfunction, Bioenergetic Defects, and the Metabolic Link to Alzheimer’s Disease; the Metabolic Impact on Neuroinflammation and Microglial Modulation in Neurodegenerative Diseases, the Impact of Circadian and Diurnal Rhythms on Cellular Metabolic Function and Neurodegenerative Diseases, and much more. Summarizes the current status of and future research in Alzheimer’s and Parkinson’s diseases Reviews the impact of the metabolic hypothesis on underlying mechanisms of neurodegenerative diseases.

Functional Medicine

• Author : Helmut W. Schimmel
• Publisher : Thieme
• Release Date : 1997
• Genre: Medical
• Pages : 412
• ISBN 10 : 3830407394

This is the updated English edition of the first volume of the acclaimed textbook by the leading German proponent of bioenergetic medicine who is also the founder of the VEGATEST-Method. Functional Medicine provides the foundation for understanding and using bioenergetics. It is grounded in both Oriental and Occidental medical knowledge and deals with the bioenergetic events which precede and accompany biochemical and organic pathology. Functional Medicine embraces the totality of regulatory functions of the organism and employs energy-oriented diagnostic methods to reveal the energetic events leading to an advanced diagnosis. The findings can then be utilized for the prevention of a disease, or in the face of the fully developed disease, they can provide the proper therapeutic guidance. The practice of functional medicine demands a thorough knowledge of clinical medicine, heteropathic, linked with a holistic attitude and a familiarity with the principles of acupuncture. It also requires a working understanding of stomatology, otorhinolaryngology and neurology. Necessary as well is manual dexterity and skill in the use of bioelectronic instrumentation. Although current conventional medicine saves lives in major acute infections and injuries, it offers very little to those with chronic disease. Functional Medicine offers a meaningful complement to clinical medicine and closes existing gaps in diagnosis and therapies.

Bioenergetics

• Author : Lars Garby
• Publisher : Cambridge University Press
• Release Date : 1995-02-24
• Genre: Medical
• Pages : 290
• ISBN 10 : 0521451434

The original authors-see later for detail