Combination Therapy Against Multidrug Resistance Book

Combination Therapy Against Multidrug Resistance


  • Author : Mohmmad Younus Wani
  • Publisher : Academic Press
  • Release Date : 2020-04-30
  • Genre: Business & Economics
  • Pages : 268
  • ISBN 10 : 9780128205785

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Combination Therapy Against Multidrug Resistance Excerpt :

Combination Therapy against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. Multidrug resistance (MDR) occurs when microorganisms such as bacteria, fungi, viruses, and parasites are excessively exposed to antimicrobial drugs such as antibiotics, antifungals, or antivirals, and in response the microorganism undergoes mutations or develops different resistance mechanisms to combat the drug for its survival. MDR is becoming an increasingly serious problem in both developed and developing nations. Bacterial resistance to antibiotics has developed faster than the production of new antibiotics, making bacterial infections increasingly difficult to treat, and the same is true for a variety of other diseases. Combination therapy proves to be a promising strategy as it offers potential benefits such as a broad spectrum of efficacy, greater potency than the drugs used in monotherapy, improved safety and tolerability, and reduction in the number of resistant organisms. This book considers how combination therapy can be applied in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Combination Therapy Against Multidrug Resistance gathers the most relevant information on the prospects of combination therapy as a strategy to combat multridrug resistance and helping to motivate the industrial sector and government agencies to invest more in research and development of this strategy as a weapon to tackle the multidrug resistance problem. It will be useful to academics and researchers involved in the development of new antimicrobial or antiinfective agents and treatment strtategies to combat multidrug resistance. Clinicians and medical nurses working in the field of infection prevention and control (IPC) will also find the book relevant Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to

Combination Therapy Against Multidrug Resistance Book

Combination Therapy Against Multidrug Resistance


  • Author : Mohmmad Younus Wani
  • Publisher : Academic Press
  • Release Date : 2020-06
  • Genre: Business & Economics
  • Pages : 260
  • ISBN 10 : 0128205768

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Combination Therapy Against Multidrug Resistance Excerpt :

Combination Therapy Against Multidrug Resistance explores the potential of combination therapy as an efficient strategy to combat multi-drug resistance. The book considers how combination therapy can apply in multiple situations, including cancer, HIV, tuberculosis, fungal infections, and more. Sections cover the most relevant information on prospects of combination therapy as a strategy to combat multidrug resistance and help motivate the industrial sector and government agencies to invest more in research and development. This comprehensive resource is useful to academics and researchers involved in the development of new antimicrobial or anti-infective agents and treatment strategies to combat multidrug resistance. Explores strategic methods with investigation of both short- and long-term goals to combat multidrug resistance Presents a broad scope to help users fully understand how to apply combined therapy to multidrug resistance Provides an overview of combination therapy, but also includes specific cases such as cancer, tuberculosis, HIV and malaria

Fighting Multidrug Resistance with Herbal Extracts  Essential Oils and Their Components Book

Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components


  • Author : Mahendra Rai
  • Publisher : Academic Press
  • Release Date : 2013-05-24
  • Genre: Medical
  • Pages : 296
  • ISBN 10 : 9780124017085

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Fighting Multidrug Resistance with Herbal Extracts Essential Oils and Their Components Excerpt :

Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components offers scientists a single source aimed at fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses and fungi using natural products. This essential reference discusses herbal extracts and essential oils used or under investigation to treat MDR infections, as well as those containing antimicrobial activity that could be of potential interest in future studies against MDR microorganisms. The need to combat multidrug-resistant microorganisms is an urgent one and this book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components and more to aid researchers in effective antimicrobial drug discovery Addresses the need to develop safe and effective approaches to coping with resistance to all classes of antimicrobial drugs Provides readers with current evidence-based content aimed at using herbal extracts and essential oils in antimicrobial drug development Includes chapters devoted to the activity of herbal products against herpes, AIDS, tuberculosis, drug-resistant cancer cells and more

Drug Discovery Targeting Drug Resistant Bacteria Book

Drug Discovery Targeting Drug Resistant Bacteria


  • Author : Prashant Kesharwani
  • Publisher : Academic Press
  • Release Date : 2020-05-15
  • Genre: Business & Economics
  • Pages : 432
  • ISBN 10 : 9780128184813

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Drug Discovery Targeting Drug Resistant Bacteria Excerpt :

Drug Discovery Targeting Drug-Resistant Bacteria explores the status and possible future of developments in fighting drug-resistant bacteria. The book covers the majority of microbial diseases and the drugs targeting them. In addition, it discusses the potential targeting strategies and innovative approaches to address drug resistance. It brings together academic and industrial experts working on discovering and developing drugs targeting drug-resistant (DR) bacterial pathogens. New drugs active against drug-resistant pathogens are discussed, along with new strategies being used to discover molecules acting via new modes of action. In addition, alternative therapies such as peptides and phages are included. Pharmaceutical scientists, microbiologists, medical professionals, pathologists, researchers in the field of drug discovery, infectious diseases and microbial drug discovery both in academia and in industrial settings will find this book helpful. Written by scientists with extensive industrial experience in drug discovery Provides a balanced view of the field, including its challenges and future directions Includes a special chapter on the identification and development of drugs against pathogens which exhibit the potential to be used as weapons of war

Antibiotic Materials in Healthcare Book

Antibiotic Materials in Healthcare


  • Author : Kokkarachedu Varaprasad
  • Publisher : Academic Press
  • Release Date : 2020-05-22
  • Genre: Science
  • Pages : 346
  • ISBN 10 : 9780128225363

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Antibiotic Materials in Healthcare Excerpt :

Antibiotic Materials in Healthcare provides significant information on antibiotic related issues, accurate solutions, and recent investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced (physical, chemical and biological) properties, an analysis of materials, in vivo and in vitro applications, and their biomedical applications for healthcare. Provides information on all aspects of antibiotic related issues Offers a balanced synthesis of basic and clinical science for each individual case, presenting clinical courses and detailed microbiological information for each infection Describes the prevalence and incidence of global issues and current therapeutic approaches

Antibiotics and Bacterial Resistance Book

Antibiotics and Bacterial Resistance


  • Author : Wiley
  • Publisher : John Wiley & Sons
  • Release Date : 2013-01-14
  • Genre: Medical
  • Pages : 146
  • ISBN 10 : 9781118580912

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Antibiotics and Bacterial Resistance Excerpt :

The need for novel antibiotics is greater now than perhaps anytime since the pre-antibiotic era. Indeed, the recent collapse ofmany pharmaceutical antibacterial groups, combined with theemergence of hypervirulent and pan-antibiotic-resistant bacteriahas severely compromised infection treatment options and led todramatic increases in the incidence and severity of bacterialinfections. This collection of reviews and laboratory protocols gives thereader an introduction to the causes of antibiotic resistance, thebacterial strains that pose the largest danger to humans (i.e.,streptococci, pneumococci and enterococci) and the antimicrobialagents used to combat infections with these organisms. Some newavenues that are being investigated for antibiotic development arealso discussed. Such developments include the discovery of agentsthat inhibit bacterial RNA degradation, the bacterial ribosome, andstructure-based approaches to antibiotic drug discovery. Two laboratory protocols are provided to illustrate differentstrategies for discovering new antibiotics. One is a bacterialgrowth inhibition assay to identify inhibitors of bacterial growththat specifically target conditionally essential enzymes in thepathway of interest. The other protocol is used to identifyinhibitors of bacterial cell-to-cell signaling. This e-book — a curated collection from eLS, WIREs, andCurrent Protocols — offers a fantastic introduction to thefield of antibiotics and antibiotic resistance for students orinterdisciplinary collaborators. Table of Contents: Introduction Antibiotics and the Evolution of Antibiotic Resistance eLS Jose L Martinez, Fernando Baquero Antimicrobials Against Streptococci, Pneumococci andEnterococci eLS Susan Donabedian, Adenike Shoyinka Techniques & Applications RNA decay: a novel therapeutic target in bacteria WIREs RNA Tess M. Eidem, Christelle M. Roux, Paul M. Dunman Antibiotics that target protein synthesis WIREs RNA Lisa S. McCoy, Yun Xie, Yitzhak Tor Methods High-Throug

Antimicrobial Resistance Book

Antimicrobial Resistance


  • Author : World Health Organization
  • Publisher : Unknown
  • Release Date : 2014
  • Genre: Medical
  • Pages : 232
  • ISBN 10 : 9241564741

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Antimicrobial Resistance Excerpt :

Summary report published as technical document with reference number: WHO/HSE/PED/AIP/2014.2.

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses Book

Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses


  • Author : OECD
  • Publisher : OECD Publishing
  • Release Date : 2020-04-01
  • Genre: Uncategoriezed
  • Pages : 250
  • ISBN 10 : 9781108864121

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Challenges to Tackling Antimicrobial Resistance Economic and Policy Responses Excerpt :

Antimicrobial resistance (AMR) is a biological mechanism whereby a microorganism evolves over time to develop the ability to become resistant to antimicrobial therapies such as antibiotics. The drivers of and potential solutions to AMR are complex, often spanning multiple sectors. The internationally recognized response to AMR advocates for a ‘One Health’ approach, which requires policies to be developed and implemented across human, animal, and environmental health.

Combination Therapy of Aids Book

Combination Therapy of Aids


  • Author : Erik De Clercq
  • Publisher : Springer Science & Business Media
  • Release Date : 2004
  • Genre: Medical
  • Pages : 243
  • ISBN 10 : 3764366001

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Combination Therapy of Aids Excerpt :

An extensive assessment of combination therapy of AIDS. Main focus is put on the Highly Active Antiretroviral Therapy (HAART) but other therapies like salvage therapy are also discussed. The chapters cover efficacy, treatment, causes of treatment failure, clinical care, guidelines, pharmacology. The volume closes with an outlook on future perspectives.

Introduction to Basics of Pharmacology and Toxicology Book

Introduction to Basics of Pharmacology and Toxicology


  • Author : Abialbon Paul
  • Publisher : Springer Nature
  • Release Date : 2021-03-13
  • Genre: Medical
  • Pages : 1175
  • ISBN 10 : 9789813360099

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Introduction to Basics of Pharmacology and Toxicology Excerpt :

This book explains the pharmacological relationships between the various systems in the human body. It offers a comprehensive overview of the pharmacology concerning the autonomic, central, and peripheral nervous systems. Presenting up-to-date information on chemical mediators and their significance, it highlights the therapeutic aspects of several diseases affecting the cardiovascular, renal, respiratory, gastrointestinal, endocrinal, and hematopoietic systems. The book also includes drug therapy for microbial and neoplastic diseases. It also comprises sections on immunopharmacology, dermatological, and ocular pharmacology providing valuable insights into these emerging and recent topics. Covering the diverse groups of drugs acting on different systems, the book reviews their actions, clinical uses, adverse effects, interactions, and subcellular mechanisms of action. It is divided into 11 parts, subdivided into several chapters that evaluate the basic pharmacological principles that govern the different types of body systems. This book is intended for academicians, researchers, and clinicians in industry and academic institutions in pharmaceutical, pharmacological sciences, pharmacy, medical sciences, physiology, neurosciences, biochemistry, molecular biology and other allied health sciences.

Antibiotics in Laboratory Medicine Book

Antibiotics in Laboratory Medicine


  • Author : Daniel Amsterdam
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2014-08-08
  • Genre: Medical
  • Pages : 832
  • ISBN 10 : 9781469883632

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Antibiotics in Laboratory Medicine Excerpt :

Antibiotics in Laboratory Medicine has been a mainstay resource for practitioners/providers, investigators, and pharmaceutical researchers of new anti-infective compounds for the past 30 years. This edition includes new chapters on the predictive value of in vitro laboratory testing and the improvement of patient care in the hospital environment through antimicrobial stewardship.