Comparative Biology of the Normal Lung Book

Comparative Biology of the Normal Lung


  • Author : Richard A. Parent
  • Publisher : Academic Press
  • Release Date : 2015-03-13
  • Genre: Science
  • Pages : 834
  • ISBN 10 : 9780124047266

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Comparative Biology of the Normal Lung Excerpt :

Comparative Biology of the Normal Lung, 2nd Edition, offers a rigorous and comprehensive reference for all those involved in pulmonary research. This fully updated work is divided into sections on anatomy and morphology, physiology, biochemistry, and immunological response. It continues to provide a unique comparative perspective on the mammalian lung. This edition includes several new chapters and expanded content, including aging and development of the normal lung, mechanical properties of the lung, genetic polymorphisms, the comparative effect of stress of pulmonary immune function, oxygen signaling in the mammalian lung and much more. By addressing scientific advances and critical issues in lung research, this 2nd edition is a timely and valuable work on comparative data for the interpretation of studies of animal models as compared to the human lung. Edited and authored by experts in the field to provide an excellent and timely review of cross-species comparisons that will help you interpret and compare data from animal studies to human findings Incorporates lung anatomy and physiology, cell specific interactions and immunological responses to provide you with a single and unique multidisciplinary source on the comparative biology of the normal lung Includes new and expanded content on neonatal and aged lungs, developmental processes, cell signaling, antioxidants, airway cells, safety pharmacology and much more Section IV on Physical and Immunological Defenses has been significantly updated with 9 new chapters and an increased focus on the pulmonary immunological system

Treatise on Pulmonary Toxicology Book

Treatise on Pulmonary Toxicology


  • Author : Richard A. Parent
  • Publisher : CRC Press
  • Release Date : 1992-02-21
  • Genre: Medical
  • Pages : 848
  • ISBN 10 : 1439805407

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Treatise on Pulmonary Toxicology Excerpt :

Comparative Biology of the Normal Lung is the first volume in a series entitled "A Comprehensive Treatise on Pulmonary Toxicology." The book is divided into four sections that deal with morphology and morphometry, respiratory physiology, biochemistry, and pulmonary defense. A special index lists and cross indexes all comparative data included in the text, which provides readers with easy access to a broad spectrum of pulmonary data for a number of different species. Over 50 internationally respected authors have contributed to this cutting -edge scientific study designed for all scientists concerned with the pulmonary system, including research scientists in medicine, veterinary medicine, zoology, and toxicology.

Handbook of Toxicology Book

Handbook of Toxicology


  • Author : Michael J. Derelanko
  • Publisher : CRC Press
  • Release Date : 2014-03-07
  • Genre: Law
  • Pages : 1022
  • ISBN 10 : 9781439890141

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Handbook of Toxicology Excerpt :

The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r

Dellmann s Textbook of Veterinary Histology Book
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Dellmann s Textbook of Veterinary Histology


  • Author : Jo Ann Eurell
  • Publisher : John Wiley & Sons
  • Release Date : 2013-03-19
  • Genre: Medical
  • Pages : 432
  • ISBN 10 : 9781118685822

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Dellmann s Textbook of Veterinary Histology Excerpt :

The leading veterinary histology text returns with a fully updated sixth edition. Written in a concise, easy-to-understand that's a pleasure to read, this new edition continues the student-friendly tradition originated by Dr. Dellman, presenting the basics of histology including cytology and microscopic anatomy. The Sixth Edition focuses on the most current knowledge of cell, tissue and organ structure and function. All information has been fully revised and updated by the authors, both experts in their fields. Written with first year veterinary students in mind, it is also an important resource for veterinarians, graduate students, and others who require information on animal tissue structure and function. Highlights of the Sixth Edition include: New images and line drawings have been added to enhance the student's understanding of concepts. Two-page insert contains full-color histology images. Comprehensive listings of suggested readings at the end of each chapter encourage further study. The text is organized by body region, allowing the presentation to emphasize comparative species information so students can better appreciate how species differ in regard to key structures. Whether you're a veterinary student or practicing professional, you should have this classic histology reference as part of your working library.

Respiratory System Book

Respiratory System


  • Author : Thomas C. Jones
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Medical
  • Pages : 357
  • ISBN 10 : 9783642610424

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Respiratory System Excerpt :

Approximately ten years have elapsed since the second volume of the International Life Sciences Institute (ILSI) Monographs on Pathology of Laboratory Animals, Respiratory System, was first completed. New in formation of interest to pathologists has developed at a rather remark able pace during these years. Exceptional progress has been made in the routine identification of enzymes and cell products in respiratory cells. A better understanding has developed on the functions of cells of the respiratory tract and of the mechanisms involved in cell metabolism, particularly those involving toxins and carcinogens. Clear concepts have developed concerning the significance of pathologic lesions, particularly in the upper respiratory tract and their relation to human health and risk assessment. Standardized nomenclature has developed significantly dur ing the lO-year period since the first edition and is being utilized on an international basis. This has resulted in significant improvement in com munication of pathologic data to regulatory agencies and in scientific publications worldwide. This monograph series and others sponsored by ILSI have had significant effects on these improved communications and the international acceptance of standardized nomenclature. In this sec ond edition, new formats have been used where more appropriate for the subjects to be covered.

Handbook of Toxicology  Second Edition Book
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Handbook of Toxicology Second Edition


  • Author : Michael J. Derelanko
  • Publisher : CRC Press
  • Release Date : 2001-08-29
  • Genre: Medical
  • Pages : 1440
  • ISBN 10 : 0849303702

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Handbook of Toxicology Second Edition Excerpt :

LOCATE FREQUENTLY USED INFORMATION EASILY AND QUICKLY Working in the laboratory or office, you use a diverse assortment of basic information to design, conduct, and interpret toxicology studies and to perform risk assessments. The Second Edition of the best-selling Handbook of Toxicology gives you the information you need in a single reference source. NEW IN THIS EDITION: Expanded coverage of inhalation toxicology, neurotoxicology, and histopathology Additional regulatory chapters dealing with pesticides, medical devices, consumer products, and world-wide notification of new chemicals Areas of toxicology missing from the first edition such as ecotoxicology and in vitro toxicology A chapter providing extensive overview of the toxicology of metals Two chapters on basic male and female endocrinology and related toxicology Information on differences in physiological and biochemical parameters between children and adults References to Web site sources of valuable information Over 200 new tables and figures THE SINGLE SOURCE FOR THE INFORMATION YOU USE MOST FREQUENTLY Updated and expanded, this unique book includes practical reference information useful to toxicologists in the chemical and pharmaceutical industries, contract laboratories, regulatory agencies, and academia. To help you find information quickly and easily, data is arranged by toxicology subspecialty and each chapter begins with a detailed listing of information presented. Containing over 700 tables and figures, Handbook of Toxicology, Second Edition gives you a single source for the information you use most often.

Chronic Obstructive Lung Diseases Book

Chronic Obstructive Lung Diseases


  • Author : Norbert F. Voelkel
  • Publisher : PMPH-USA
  • Release Date : 2008
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 1550093908

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Chronic Obstructive Lung Diseases Excerpt :

This clinical reference for practitioners offers a new and comprehensive look at chronic obstructive lung disease. Global in scale and importance, it is an important cause of morbidity and mortality. Bringing together a roster of internationally renowned contributors from the front lines of pulmonary medicine and research, it is aimed at practitioners in pulmonary medicine, pathology, thoracic radiology and epidemiology. Its focus is on the pathobiology of chronic obstructive pathology disease and emphysema and its exacerbation of chronic obstructive pulmonary disease and on treatment options. This reference works to 'connect the dots' by collating and centralizing the various data on the subject.

Concepts In Inhalation Toxicology Book

Concepts In Inhalation Toxicology


  • Author : Roger O. McClellan
  • Publisher : CRC Press
  • Release Date : 1995-09-25
  • Genre: Medical
  • Pages : 648
  • ISBN 10 : 1439805571

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Concepts In Inhalation Toxicology Excerpt :

Recent developments have provided new data on the subject of inhalation toxicology, requiring an update of the previous edition of this popular text. Like the first, this second edition explains the basic concepts and quantitative approaches in inhalation toxicology, and it gives a comprehensive treatment of evaluations of respiratory responses to inhaled particles and gases. The author here explores new understanding of the role of cytokines in pulmonary inflammation and risk assessment. Immunologists, oncologists, respiratory specialists and students in those fields will find Concepts In Inhalation Toxicology to be essential to their practice.

Boorman s Pathology of the Rat Book

Boorman s Pathology of the Rat


  • Author : Andrew W. Suttie
  • Publisher : Academic Press
  • Release Date : 2017-12-18
  • Genre: Medical
  • Pages : 748
  • ISBN 10 : 9780123914897

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Boorman s Pathology of the Rat Excerpt :

Boorman’s Pathology of the Rat: Reference and Atlas, Second Edition, continues its history as the most comprehensive pathology reference on rat strains for researchers across science and medicine using rat models in the laboratory. It offers readers an added emphasis on the Sprague-Dawley and Wistar rat strains that is consistent with current research across academia, government, and industry. In addition, the book provides standard diagnostic criteria, basic content on histology, histological changes that result from drug toxicity and neoplasm, pathology terminology, and four-color photographs from the NTP archive and database. With updated references and photographs, as well as coverage of all rat strains, this book is not only the standard in the field, but also an invaluable resource for toxicologists, biologists, and other scientists engaged in regulatory toxicology who must make the transition from pathology results to the promulgation of meaningful regulations. Contains full, four color photographs from the NTP archive and database and coverage of all rat strains Provides an organ-by-organ and system-by-system approach that presents standard diagnostic criteria and basic content on histology and histological changes Includes comprehensive and detailed background incidence data Presents detailed descriptive content regarding changes in rat models during research

Respiratory Physiology of Newborn Mammals Book

Respiratory Physiology of Newborn Mammals


  • Author : Jacopo P. Mortola
  • Publisher : JHU Press
  • Release Date : 2003-04-30
  • Genre: Science
  • Pages : 368
  • ISBN 10 : 9780801873669

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Respiratory Physiology of Newborn Mammals Excerpt :

It will be of value to researchers, clinicians, and students interested in developmental physiology, comparative biology, and zoology, as well as neonatalogists and pediatric pulmonologists who are interested in alternative perspectives on current clinical practice.

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research Book

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research


  • Author : Robert L. Maynard
  • Publisher : Academic Press
  • Release Date : 2019-02-08
  • Genre: Medical
  • Pages : 378
  • ISBN 10 : 9780128118719

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Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research Excerpt :

Anatomy and Histology of the Laboratory Rat in Toxicology and Biomedical Research presents the detailed systematic anatomy of the rat, with a focus on toxicological needs. Most large works dealing with the laboratory rat provide a chapter on anatomy, but fall far short of the detailed account in this book which also focuses on the needs of toxicologists and others who use the rat as a laboratory animal. The book includes detailed guides on dissection methods and the location of specific tissues in specific organ systems. Crucially, the book includes classic illustrations from Miss H. G. Q. Rowett, along with new color photo-micrographs. Written by two of the top authors in their fields, this book can be used as a reference guide and teaching aid for students and researchers in toxicology. In addition, veterinary/medical students, researchers who utilize animals in biomedical research, and researchers in zoology, comparative anatomy, physiology and pharmacology will find this book to be a great resource. Illustrated with over 100 black and white and color images to assist understanding Contains detailed descriptions and explanations to accompany all images, thus helping with self-study Designed for toxicologic research for people from diverse backgrounds, including biochemistry, pharmacology, physiology, immunology and general biomedical sciences

Pharmaceutical Inhalation Aerosol Technology  Third Edition Book

Pharmaceutical Inhalation Aerosol Technology Third Edition


  • Author : Anthony J. Hickey
  • Publisher : CRC Press
  • Release Date : 2019-03-26
  • Genre: Medical
  • Pages : 730
  • ISBN 10 : 9780429619564

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Pharmaceutical Inhalation Aerosol Technology Third Edition Excerpt :

This fully revised and updated third edition of Pharmaceutical Inhalation Aerosol Technology encompasses the scientific and technical foundation for the rationale, design, componentry, assembly and quality performance metrics of therapeutic inhalers in their delivery of pharmaceutical aerosols to treat symptoms or the underlying causes of disease. It focuses on the importance of pharmaceutical engineering as a foundational element of all inhaler products and their application to pulmonary drug delivery. The expanded scope considers previously unaddressed aspects of pharmaceutical inhalation aerosol technology and the patient interface by including aerosol delivery, lung deposition and clearance that are used as measures of effective dose delivery.

Pulmonary Immunotoxicology Book

Pulmonary Immunotoxicology


  • Author : Mitchell D. Cohen
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Medical
  • Pages : 465
  • ISBN 10 : 9781461545354

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Pulmonary Immunotoxicology Excerpt :

Pulmonary Immunotoxicology is a comprehensive exploration of the effects of various inhaled materials upon the immune system of the respiratory tract. It will be useful to investigators in the field of pulmonary toxicology and immunotoxicology, and to those involved in administration and regulation of matters related to inhaled materials. It can also serve as a textbook for a course in pulmonary immunotoxicology at graduate or advanced undergraduate level. Pulmonary Immunotoxicology comprises four sections. The first provides basic background concepts essential for understanding pulmonary immunotoxicology, including discussions of the normal structure and function of the respiratory system, its basic immunology, and the manner by which inhaled particles and gases are removed from the air and deposited upon respiratory tract surfaces. The second section provides an overview of the major types of pathological consequences which can arise from immunomodulation within the respiratory tract, including hypersensitivity and asthma, inflammation and fibrosis, as well as immunosuppression and autoimmunity. The third section, which comprises the largest portion of the book, deals specifically with major classes of airborne agents that are known to alter the immune function of the respiratory tract. These are arranged into major classes: organic agents, metals, gases, particles, biologics, and complex mixtures. The fourth and final section of the book explores the area of risk assessment, including discussions of the basic concepts of risk assessment as they apply specifically to immunotoxicologic effects upon the lungs, and the use of biomarkers as indices of potential pulmonary immunotoxic responses to inhaled materials.