Computer Aided Vaccine Design Book

Computer Aided Vaccine Design


  • Author : Joo Chuan Tong
  • Publisher : Elsevier
  • Release Date : 2013-07-31
  • Genre: Medical
  • Pages : 164
  • ISBN 10 : 9781908818416

DOWNLOAD BOOK
Computer Aided Vaccine Design Excerpt :

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. Computer-aided vaccine design is a comprehensive introduction to this exciting field of study. The book is intended to be a textbook for researchers and for courses in bioinformatics, as well as a laboratory reference guide. It is written mainly for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used, as well as limitations of the methods and strategies for their use. Chapters include: MHC and T cell responses; Immunoglobulins and B cell responses; Scientific publications and databases; Database design; Computational T cell vaccine design; Computational B cell vaccine design; infectious disease informatics; Vaccine safety and quality assessments; and Vaccine adjuvant informatics. Essential reading for any biologist who wants to understand methods of computer-aided vaccine design Description of available data sources and publicly available software, with detailed analysis of strengths and weaknesses Theoretical concepts and practical examples of database design and development for a virtual screening campaign

Computer aided Vaccine Design Book

Computer aided Vaccine Design


  • Author : Joo Chuan Tong
  • Publisher : Woodhead Pub Limited
  • Release Date : 2013
  • Genre: Medical
  • Pages : 135
  • ISBN 10 : 1907568417

DOWNLOAD BOOK
Computer aided Vaccine Design Excerpt :

Computational pre-screening of antigens is now routinely applied to the discovery of vaccine candidates. This textbook is a comprehensive introduction and laboratory reference guide to this exciting field of study. It was written primarily for biologists who want to understand the current methods of computer-aided vaccine design. The contents are designed to help biologists appreciate the underlying concepts and algorithms used and the limitations of the methods and strategies for their use.

Synthetic Peptide Vaccine Models Book

Synthetic Peptide Vaccine Models


  • Author : Mesut Karahan
  • Publisher : CRC Press
  • Release Date : 2021-03-01
  • Genre: Science
  • Pages : 292
  • ISBN 10 : 9781000342772

DOWNLOAD BOOK
Synthetic Peptide Vaccine Models Excerpt :

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Computer Aided Drug Design Book

Computer Aided Drug Design


  • Author : Dev Bukhsh Singh
  • Publisher : Springer Nature
  • Release Date : 2020-10-09
  • Genre: Medical
  • Pages : 306
  • ISBN 10 : 9789811568152

DOWNLOAD BOOK
Computer Aided Drug Design Excerpt :

This book provides up-to-date information on bioinformatics tools for the discovery and development of new drug molecules. It discusses a range of computational applications, including three-dimensional modeling of protein structures, protein-ligand docking, and molecular dynamics simulation of protein-ligand complexes for identifying desirable drug candidates. It also explores computational approaches for identifying potential drug targets and for pharmacophore modeling. Moreover, it presents structure- and ligand-based drug design tools to optimize known drugs and guide the design of new molecules. The book also describes methods for identifying small-molecule binding pockets in proteins, and summarizes the databases used to explore the essential properties of drugs, drug-like small molecules and their targets. In addition, the book highlights various tools to predict the absorption, distribution, metabolism, excretion (ADME) and toxicity (T) of potential drug candidates. Lastly, it reviews in silico tools that can facilitate vaccine design and discusses their limitations.

Immunoinformatics Book

Immunoinformatics


  • Author : Christian Schönbach
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-21
  • Genre: Medical
  • Pages : 200
  • ISBN 10 : 9780387729688

DOWNLOAD BOOK
Immunoinformatics Excerpt :

In contrast to existing books on immunoinformatics, this volume presents a cross-section of immunoinformatics research. The contributions highlight the interdisciplinary nature of the field and how collaborative efforts among bioinformaticians and bench scientists result in innovative strategies for understanding the immune system. Immunoinformatics is ideal for scientists and students in immunology, bioinformatics, microbiology, and many other disciplines.

Immunoinformatics Book

Immunoinformatics


  • Author : Namrata Tomar
  • Publisher : Humana
  • Release Date : 2021-03-26
  • Genre: Medical
  • Pages : 409
  • ISBN 10 : 1071603914

DOWNLOAD BOOK
Immunoinformatics Excerpt :

This book covers a wide range of diverse immunoinformatics research topics, involving tools and databases of potential epitope prediction, HLA gene analysis, MHC characterizing, in silico vaccine design, mathematical modeling of host-pathogen interactions, and network analysis of immune system data. In that way, this fully updated volume explores the enormous value of computational tools and models in immunology research. Written for the highly successful Methods in Molecular Biology series, chapters include the kind of key insights and detailed implementation advice to encourage successful results in the lab. Authoritative and practical, Immunoinformatics, Third Edition serves as an ideal guide for scientists working at the intersection of bioinformatics, mathematical modelling, and statistics for the study of immune systems biology.

Vaccine Design Book

Vaccine Design


  • Author : Rino Rappuoli
  • Publisher : Caister Academic Press
  • Release Date : 2011
  • Genre: Medical
  • Pages : 380
  • ISBN 10 : 1904455743

DOWNLOAD BOOK
Vaccine Design Excerpt :

In this book, expert international authors critically review the current cutting-edge research in vaccine design and development. Particular emphasis is given to new approaches and technologies.

Immunoinformatics Book

Immunoinformatics


  • Author : Darren R. Flower
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-02-07
  • Genre: Science
  • Pages : 438
  • ISBN 10 : 9781603271189

DOWNLOAD BOOK
Immunoinformatics Excerpt :

This volume both engages the reader and provides a sound foundation for the use of immunoinformatics techniques in immunology and vaccinology. It addresses databases, HLA supertypes, MCH binding, and other properties of immune systems. The book contains chapters written by leaders in the field and provides a firm background for anyone working in immunoinformatics in one easy-to-use, insightful volume.

Applied Bioinformatics Book

Applied Bioinformatics


  • Author : Paul Maria Selzer
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-01-18
  • Genre: Science
  • Pages : 287
  • ISBN 10 : 9783540728009

DOWNLOAD BOOK
Applied Bioinformatics Excerpt :

At last, here is a baseline book for anyone who is confused by cryptic computer programs, algorithms and formulae, but wants to learn about applied bioinformatics. Now, anyone who can operate a PC, standard software and the internet can also learn to understand the biological basis of bioinformatics, of the existence as well as the source and availability of bioinformatics software, and how to apply these tools and interpret results with confidence. This process is aided by chapters that introduce important aspects of bioinformatics, detailed bioinformatics exercises (including solutions), and to cap it all, a glossary of definitions and terminology relating to bioinformatics.

21st European Symposium on Computer Aided Process Engineering Book

21st European Symposium on Computer Aided Process Engineering


  • Author : E. N. Pistikopoulos
  • Publisher : Elsevier
  • Release Date : 2011-07-21
  • Genre: Science
  • Pages : 2087
  • ISBN 10 : 9780444538956

DOWNLOAD BOOK
21st European Symposium on Computer Aided Process Engineering Excerpt :

The European Symposium on Computer Aided Process Engineering (ESCAPE) series presents the latest innovations and achievements of leading professionals from the industrial and academic communities. The ESCAPE series serves as a forum for engineers, scientists, researchers, managers and students to present and discuss progress being made in the area of computer aided process engineering (CAPE). European industries large and small are bringing innovations into our lives, whether in the form of new technologies to address environmental problems, new products to make our homes more comfortable and energy efficient or new therapies to improve the health and well being of European citizens. Moreover, the European Industry needs to undertake research and technological initiatives in response to humanity's "Grand Challenges," described in the declaration of Lund, namely, Global Warming, Tightening Supplies of Energy, Water and Food, Ageing Societies, Public Health, Pandemics and Security. Thus, the Technical Theme of ESCAPE 21 will be "Process Systems Approaches for Addressing Grand Challenges in Energy, Environment, Health, Bioprocessing & Nanotechnologies."

Scientific Modeling and Simulations Book

Scientific Modeling and Simulations


  • Author : Sidney Yip
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-04-07
  • Genre: Science
  • Pages : 402
  • ISBN 10 : 9781402097416

DOWNLOAD BOOK
Scientific Modeling and Simulations Excerpt :

Although computational modeling and simulation of material deformation was initiated with the study of structurally simple materials and inert environments, there is an increasing demand for predictive simulation of more realistic material structure and physical conditions. In particular, it is recognized that applied mechanical force can plausibly alter chemical reactions inside materials or at material interfaces, though the fundamental reasons for this chemomechanical coupling are studied in a material-speci c manner. Atomistic-level s- ulations can provide insight into the unit processes that facilitate kinetic reactions within complex materials, but the typical nanosecond timescales of such simulations are in contrast to the second-scale to hour-scale timescales of experimentally accessible or technologically relevant timescales. Further, in complex materials these key unit processes are “rare events” due to the high energy barriers associated with those processes. Examples of such rare events include unbinding between two proteins that tether biological cells to extracellular materials [1], unfolding of complex polymers, stiffness and bond breaking in amorphous glass bers and gels [2], and diffusive hops of point defects within crystalline alloys [3].

The Design and Development of Novel Drugs and Vaccines Book

The Design and Development of Novel Drugs and Vaccines


  • Author : Tarun Kumar Bhatt
  • Publisher : Academic Press
  • Release Date : 2021-01-21
  • Genre: Business & Economics
  • Pages : 308
  • ISBN 10 : 9780128214756

DOWNLOAD BOOK
The Design and Development of Novel Drugs and Vaccines Excerpt :

The Design and Development of Novel Drugs and Vaccines: Principles and Protocols presents both in silico methods and experimental protocols for vaccine and drug design and development, critically reviewing the most current research and emphasizing approaches and technologies that accelerate and lower the cost of product development. Sections review the technologies and approaches used to identify, characterize and establish a protein as a new drug and vaccine target, cover several molecular methods for in vitro studies of the desired target, and present various physiological parameters for in vivo studies. The book includes preclinical trials and research, along with information on FDA approval. Covers both in silico methods and experimental protocols for vaccine and drug development in a single, accessible volume Offers a holistic accounting of how developments in bioinformatics and large experimental datasets can be used in the development of vaccines and drugs Shows researchers the entire gamut of current therapies, ranging from computational inputs to animal studies Reviews the most current, cutting-edge research available on vaccine and drug design and development

Molecular Docking for Computer Aided Drug Design Book

Molecular Docking for Computer Aided Drug Design


  • Author : S. Mohane Coumar
  • Publisher : Academic Press
  • Release Date : 2021-02-17
  • Genre: Medical
  • Pages : 520
  • ISBN 10 : 9780128223130

DOWNLOAD BOOK
Molecular Docking for Computer Aided Drug Design Excerpt :

Molecular Docking for Computer-Aided Drug Design: Fundamentals, Techniques, Resources and Applications offers in-depth coverage on the use of molecular docking for drug design. The book is divided into three main sections that cover basic techniques, tools, web servers and applications. It is an essential reference for students and researchers involved in drug design and discovery. Covers the latest information and state-of-the-art trends in structure-based drug design methodologies Includes case studies that complement learning Consolidates fundamental concepts and current practice of molecular docking into one convenient resource