Conjugate Addition Reactions in Organic Synthesis Book

Conjugate Addition Reactions in Organic Synthesis


  • Author : P. Perlmutter
  • Publisher : Elsevier
  • Release Date : 2013-10-22
  • Genre: Science
  • Pages : 394
  • ISBN 10 : 9781483293783

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Conjugate Addition Reactions in Organic Synthesis Excerpt :

This book provides an introduction to the chemistry of conjugate reactions, a group of reactions that constitute one of the most important classes of chemical reactions in organic synthesis. The book is organised in terms of the major classes of conjugate acceptors. Within each of these classes, the chemistry and applications of conjugate additions with several different categories of nucleophiles have been examined. Where several different nucleophiles achieve the same synthetic transformation, they are cross-referenced within the book and qualitative comparisons offered where appropriate. Examples of the use of conjugate additions in total synthesis of important molecules are included, with a special emphasis throughout the book on stereoselectivity. This will be a useful main text for graduate and postgraduate courses on conjugate addition reactions or the Michael reaction. It could also serve as a supplementary text for courses on topics such as the chemistry of organocopper reagents, enamines and carbanion chemistry.

Organocatalytic Enantioselective Conjugate Addition Reactions Book

Organocatalytic Enantioselective Conjugate Addition Reactions


  • Author : Dolores Badia
  • Publisher : Royal Society of Chemistry
  • Release Date : 2010
  • Genre: Science
  • Pages : 365
  • ISBN 10 : 9781849730242

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Organocatalytic Enantioselective Conjugate Addition Reactions Excerpt :

This book, unique in its field, is a comprehensive description of all the methodologies reported for carrying out conjugate addition reactions in a stereoselective way, using small chiral organic molecules as catalysts (organocatalysts). In the last 3-4 years, this has been a rapidly growing field in organic chemistry, and many papers have appeared reporting excellent protocols for carrying out these highly efficient transformations that compete well with other classical approachse using transition metal catalysts. A particularly attractive feature of this transformation relies upon the fact that the conjugate addition (Michael and Hetero-Michael reactions) is an extraoridinarily effective means to initiate cascade processes which result in the formation of complex molecules from very small and simple starting blocks. The book, written by noted experts, covers all recent advances in this not topic, and provides a good state-of-the-art review for organic chemists working in this field and all those who wish to start projects in this area. The Series is intended to provide an accessible reference for postgraduates and industrialists working in the field of catalysis and its applications. Books will be produced either as monographs or reference handbooks. The Series will cover research developments and applications of catalysis, in both academia and industry.

The Chemistry of Organocopper Compounds Book

The Chemistry of Organocopper Compounds


  • Author : Zvi Rappoport
  • Publisher : John Wiley & Sons
  • Release Date : 2009-12-21
  • Genre: Science
  • Pages : 1183
  • ISBN 10 : 9780470772966

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The Chemistry of Organocopper Compounds Excerpt :

Copper in organic synthesis has seen a tremendous development over the past ten years. This text represents the most comprehensive survey on the use of Copper and Cuprates in organic synthesis. The first time that the Patai Series touches on Copper compounds, it contains contributions by leading experts, and delivers the quality expected from the Patai Series.

Comprehensive Organic Synthesis  Additions to and substitutions at C C pi  Bonds Book

Comprehensive Organic Synthesis Additions to and substitutions at C C pi Bonds


  • Author : Barry M. Trost
  • Publisher : Elsevier
  • Release Date : 1991
  • Genre: Science
  • Pages : 1328
  • ISBN 10 : 0080405959

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Comprehensive Organic Synthesis Additions to and substitutions at C C pi Bonds Excerpt :

Volume 4 focuses on additions and the resulting substitutions at carbon-carbon &pgr;-bonds. Part 1 includes processes generally considered as simple polar reactions, reactive electrophiles and nucleophiles adding to alkenes and alkynes. A major topic is Michael-type addition to electron deficient &pgr;-bonds, featured in the first six chapters. In part 2 are collected the four general processes leading to nucleophilic aromatic substitution, including radical chain processes and transition metal activation through to &pgr;-complexation. Metal-activated addition (generally by nucleophiles) to alkenes and polyenes is presented in part 3, including allylic alkylation catalyzed by palladium. The coverage of nonpolar additions in part 4 includes radical additions, organometal addition (Heck reaction), carbene addition, and 1,3-dipolar cycloadditions.

Advanced Organic Chemistry Book
Score: 4.5
From 2 Ratings

Advanced Organic Chemistry


  • Author : Reinhard Bruckner
  • Publisher : Elsevier
  • Release Date : 2001-08-03
  • Genre: Science
  • Pages : 636
  • ISBN 10 : 9780080498805

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Advanced Organic Chemistry Excerpt :

A best-selling mechanistic organic chemistry text in Germany, this text's translation into English fills a long-existing need for a modern, thorough and accessible treatment of reaction mechanisms for students of organic chemistry at the advanced undergraduate and graduate level. Knowledge of reaction mechanisms is essential to all applied areas of organic chemistry; this text fulfills that need by presenting the right material at the right level.

Comprehensive Organic Functional Group Transformations Book

Comprehensive Organic Functional Group Transformations


  • Author : Alan R. Katritzky
  • Publisher : Elsevier
  • Release Date : 1995
  • Genre: Science
  • Pages : 1452
  • ISBN 10 : 0080423221

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Comprehensive Organic Functional Group Transformations Excerpt :

This Volume covers the formation of carbon-carbon single-, double- and triple bonds by substitution and addition reactions as well as by various rearrangements. The formation of carbon-carbon multiple bonds by elimination and condensation procedures is fully documented. In addition the synthesis of carbon-hydrogen bonds principally by substitution and addition reactions is featured as is the preparation of a wide variety of carbon-centred anions, cations and radicals.

Comprehensive Organic Synthesis Book

Comprehensive Organic Synthesis


  • Author : Anonim
  • Publisher : Newnes
  • Release Date : 2014-02-14
  • Genre: Science
  • Pages : 9806
  • ISBN 10 : 9780080977430

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Comprehensive Organic Synthesis Excerpt :

The second edition of Comprehensive Organic Synthesis—winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers—builds upon the highly respected first edition in drawing together the new common themes that underlie the many disparate areas of organic chemistry. These themes support effective and efficient synthetic strategies, thus providing a comprehensive overview of this important discipline. Fully revised and updated, this new set forms an essential reference work for all those seeking information on the solution of synthetic problems, whether they are experienced practitioners or chemists whose major interests lie outside organic synthesis. In addition, synthetic chemists requiring the essential facts in new areas, as well as students completely new to the field, will find Comprehensive Organic Synthesis, Second Edition an invaluable source, providing an authoritative overview of core concepts. Winner of the 2015 PROSE Award for Multivolume Reference/Science from the Association of American Publishers Contains more than170 articles across nine volumes, including detailed analysis of core topics such as bonds, oxidation, and reduction Includes more than10,000 schemes and images Fully revised and updated; important growth areas—including combinatorial chemistry, new technological, industrial, and green chemistry developments—are covered extensively

Stereoselective Multiple Bond Forming Transformations in Organic Synthesis Book

Stereoselective Multiple Bond Forming Transformations in Organic Synthesis


  • Author : Jean Rodriguez
  • Publisher : John Wiley & Sons
  • Release Date : 2015-04-27
  • Genre: Science
  • Pages : 471
  • ISBN 10 : 9781118672716

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Stereoselective Multiple Bond Forming Transformations in Organic Synthesis Excerpt :

Combining the important research topic of multiple bond-forming transformations with green chemistry, this book helps chemists identify recent sustainable stereoselective synthetic sequences. • Combines the important research topic of multiple bond-forming transformations with green chemistry and sustainable development • Offers a valuable resource for preparing compounds with multiple stereogenic centers, an important field for synthetic chemists • Organizes chapters by molecular structure of final products, making for a handbook-style resource • Discusses applications of the synthesis of natural products and of drug intermediates • Brings together otherwise-scattered information about a number of key, efficient chemical reactions

Advanced Organic Chemistry Book
Score: 5
From 1 Ratings

Advanced Organic Chemistry


  • Author : Francis A. Carey
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-09-06
  • Genre: Medical
  • Pages : 1344
  • ISBN 10 : 9780387683508

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Advanced Organic Chemistry Excerpt :

The two-part, fifth edition of Advanced Organic Chemistry has been substantially revised and reorganized for greater clarity. The material has been updated to reflect advances in the field since the previous edition, especially in computational chemistry. Part B describes the most general and useful synthetic reactions, organized on the basis of reaction type. It can stand-alone; together, with Part A: Structure and Mechanisms, the two volumes provide a comprehensive foundation for the study in organic chemistry. Companion websites provide digital models for students and exercise solutions for instructors.

Green Techniques for Organic Synthesis and Medicinal Chemistry Book

Green Techniques for Organic Synthesis and Medicinal Chemistry


  • Author : Wei Zhang
  • Publisher : John Wiley & Sons
  • Release Date : 2012-07-23
  • Genre: Medical
  • Pages : 769
  • ISBN 10 : 9780470711514

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Green Techniques for Organic Synthesis and Medicinal Chemistry Excerpt :

Green chemistry is a new way of looking at organic synthesis and the design of drug molecules, offering important environmental and economic advantages over traditional synthetic processes. Pharmaceutical companies are increasingly turning to the principles of green chemistry in an effort to reduce waste, reduce costs and develop environmentally benign processes. Green Techniques for Organic Synthesis and Medicinal Chemistry presents an overview of the established and emerging techniques in green organic chemistry, highlighting their applications in medicinal chemistry. The book is divided into four parts: Introduction: Introduces the reader to the toxicology of organic chemicals,their environmental impact, and the concept of green chemistry. Green Catalysis: Covers a variety of green catalytic techniques including organocatalysis, supported catalysis, biocatalysis, fluorous catalysis, and catalytic direct C-H bond activation reactions. Green Synthetic Techniques: Presents a series of new techniques, assessing the green chemistry aspects and limitations (i.e. cost, equipment, expertise). Techniques include reactions in alternative solvents, atom economic multicomponent reactions, microwave and ultrasonic reactions, solid-supported synthesis, fluorous and ionic liquid-based recycling techniques, and flow reactors. Green Techniques in Pharmaceutical Industry: Covers applications of green chemistry concepts and special techniques for medicinal chemistry, including synthesis, analysis, separation, formulation, , and drug delivery. Process and business case studies are included to illustrate the applications in the pharmaceutical industry. Green Techniques for Organic Synthesis and Medicinal Chemistry is an essential resource on green chemistry technologies for academic researchers, R&D professionals and students working in organic chemistry and medicinal chemistry.

Catalytic Asymmetric Conjugate Reactions Book

Catalytic Asymmetric Conjugate Reactions


  • Author : Armando Cordova
  • Publisher : John Wiley & Sons
  • Release Date : 2010-12-01
  • Genre: Science
  • Pages : 464
  • ISBN 10 : 3527632093

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Catalytic Asymmetric Conjugate Reactions Excerpt :

This unique and long-awaited handbook on this important topic in the hot field of stereoselective organic synthesis covers several types of nucleophiles. Top international authors deal with modern forms of achieving stereoselective conjugate additions based on the use of chiral auxiliaries or asymmetric catalysis, such as P-N ligands, organocatalysis, domino reactions, Lewis acid and base catalysis. There is also a discussion of the employment of enantioselective conjugate addition transformations in total synthesis of important molecules. With its reliable and previously unpublished experimental procedures, this is a true source of high quality information.

Current Trends in Organic Synthesis Book

Current Trends in Organic Synthesis


  • Author : Carlo Scolastico
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 369
  • ISBN 10 : 9781461548010

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Current Trends in Organic Synthesis Excerpt :

The last two decades have seen a rapid growth in the synthetic processing of both simple and complex molecules, aimed at meeting the needs of society in all aspects of life. Many efforts have been devoted to the development of new biologically active compounds, new materials with innovative properties such as bio-compatibility, new catalysts that allow highly selective transformations, and technologies that facilitate the synthetic pro cesses. This book is a compendium of recent progress in all these aspects of synthetic chemistry. It collects the lectures of the XII International Conference on Organic Synthesis, held in Venice from June 28 to July 2, 1998, in which the present state of art of this discipline has been reported. The topics covered include: combinatorial chemistry, new synthetic methods, stereo selective synthesis, metal-mediated synthesis, and target oriented synthesis. The book collects the contributions, in the mentioned topics, of 43 scientists from 19 different countries. The contributions presented in the Conference as plenary lectures are reported in the first section of the book. Particular attention has been dedicated to combinatorial chemistry, a new and promising methodology for the synthesis of libraries of pharmaco logically interesting compounds in order to allow the automatic pharmacological screening of thousands of compounds. The Conference has dedicated to combinatorial chemistry a mini-symposium in which scientists from academy and companies have described the current trends of this very new technology.

Chiral Lewis Acids in Organic Synthesis Book

Chiral Lewis Acids in Organic Synthesis


  • Author : Jacek Mlynarski
  • Publisher : John Wiley & Sons
  • Release Date : 2017-06-26
  • Genre: Technology & Engineering
  • Pages : 260
  • ISBN 10 : 9783527802135

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Chiral Lewis Acids in Organic Synthesis Excerpt :

A complete overview covering the application of metal-based chiral Lewis acids from all parts of the periodic table, the Author emphasizes the most recent contributions to the field as well as prominent direction of development. The book discusses the design of chiral complexes as well as a wide spectrum of reactions promoted by various chiral Lewis acids, including water-compatible acids as well as the most important applications in the chemical and pharmaceutical industries. A must-have for catalytic and organic chemists working in the field, both in academia and industry, as well as pharmaceutical and medicinal chemists.

Organic Reactions Book

Organic Reactions


  • Author : Anonim
  • Publisher : John Wiley & Sons
  • Release Date : 2016-08-03
  • Genre: Science
  • Pages : 952
  • ISBN 10 : 9781119291596

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Organic Reactions Excerpt :

The latest volume in this series for organic chemists in industry presents critical discussions of widely used organic reactions or particular phases of a reaction. The material is treated from a preparative viewpoint, with emphasis on limitations, interfering influences, effects of structure and the selection of experimental techniques. The work includes tables that contain all possible examples of the reaction under consideration. Detailed procedures illustrate the significant modifications of each method.

Organic Chemistry Book

Organic Chemistry


  • Author : Pierre Vogel
  • Publisher : John Wiley & Sons
  • Release Date : 2019-10-07
  • Genre: Science
  • Pages : 1382
  • ISBN 10 : 9783527345328

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Organic Chemistry Excerpt :

Provides the background, tools, and models required to understand organic synthesis and plan chemical reactions more efficiently Knowledge of physical chemistry is essential for achieving successful chemical reactions in organic chemistry. Chemists must be competent in a range of areas to understand organic synthesis. Organic Chemistry provides the methods, models, and tools necessary to fully comprehend organic reactions. Written by two internationally recognized experts in the field, this much-needed textbook fills a gap in current literature on physical organic chemistry. Rigorous yet straightforward chapters first examine chemical equilibria, thermodynamics, reaction rates and mechanisms, and molecular orbital theory, providing readers with a strong foundation in physical organic chemistry. Subsequent chapters demonstrate various reactions involving organic, organometallic, and biochemical reactants and catalysts. Throughout the text, numerous questions and exercises, over 800 in total, help readers strengthen their comprehension of the subject and highlight key points of learning. The companion Organic Chemistry Workbook contains complete references and answers to every question in this text. A much-needed resource for students and working chemists alike, this text: -Presents models that establish if a reaction is possible, estimate how long it will take, and determine its properties -Describes reactions with broad practical value in synthesis and biology, such as C-C-coupling reactions, pericyclic reactions, and catalytic reactions -Enables readers to plan chemical reactions more efficiently -Features clear illustrations, figures, and tables -With a Foreword by Nobel Prize Laureate Robert H. Grubbs Organic Chemistry: Theory, Reactivity, and Mechanisms in Modern Synthesis is an ideal textbook for students and instructors of chemistry, and a valuable work of reference for organic chemists, physical chemists, and chemical engineers.