Cord Blood Stem Cells Medicine Book

Cord Blood Stem Cells Medicine


  • Author : Catherine Stavropoulos-Giokas
  • Publisher : Elsevier
  • Release Date : 2014-12-03
  • Genre: Science
  • Pages : 398
  • ISBN 10 : 9780124078369

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Cord Blood Stem Cells Medicine Excerpt :

Cord Blood Stem Cells and Regenerative Medicine discusses the current applications for cord blood stem cells and techniques for banking cord blood. Cord blood, blood from the umbilical cord and placenta of an infant, represents an alternate source of stem cells that can be used to treat a myriad of disorders. Cord blood stem cells are being used more frequently and studied more seriously, as evidenced by the explosion of scientific literature on the topic. Currently, clinical and pre-clinical trials are being done in the field, treating conditions as severe as heart failure. Coupled with regenerative medicine, cord blood stem cells potentially carry the future of research and medicine in treating tissue damage, genetic disorders, and degenerative diseases. Read about new applications for cord blood stem cells and new techniques for banking cord blood — the future of regenerative medicine therapy. Comprehensive coverage of the medical application of cord blood stem cells Practical guide for usage of allogeneic and autologous cord blood in regenerative medicine Covers new applications of cord blood stem cells, particularly transplantation and HIV Introduces new technologies for cord blood stem cells and regenerative medicine

Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine Book

Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine


  • Author : Ana Colette Maurício
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-01-11
  • Genre: Science
  • Pages : 258
  • ISBN 10 : 9789535128656

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Umbilical Cord Blood Banking for Clinical Application and Regenerative Medicine Excerpt :

Umbilical cord blood (UCB) and, more recently, umbilical cord tissue (UCT) have been stored cryopreserved in private and public cord blood and tissue banks worldwide, since the umbilical cord blood was used for the first time in a child with Fanconi anemia with his HLA-identical sibling, following strict guidelines that imply high-quality standards and total rastreability of these units. The hematopoietic stem cells (HSCs) are clinically used in hematopoietic treatments for blood disorders and hemato-oncological diseases. Also, the mesenchymal stem cells (MSCs) isolated from the UCT and UCB, nowadays, can be used as coadjuvants of hematopoietic transplants. In the near future, these stem cells will have a crucial role in regenerative medicine. For this reason, these cells have been tested in several clinical trials and compassive treatments in children and adults, concerning a wide range of pathologies and diseases, for instance, for the treatment of cerebral paralysis. Considering the worldwide availability of UCB and UCT units and the absence of ethical concerns will probably become the best sources for cell-based therapies for hematological and nonhematological pathologies. The UCB will also have a crucial role in neonatology-predictive analysis in the near future.

Umbilical Cord Blood Book

Umbilical Cord Blood


  • Author : Suzanne Kadereit
  • Publisher : World Scientific
  • Release Date : 2010-03-01
  • Genre: Science
  • Pages : 347
  • ISBN 10 : 9789812833297

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Umbilical Cord Blood Excerpt :

Umbilical cord blood, previously discarded after birth, has emerged over recent years as an alternative source of hematopoietic stem cells for hematological reconstitution, mainly for leukemia patients, as well as for some hematological deficiencies and bone marrow failures. In recent years, it has become increasingly clear that cord blood, as well as the surrounding tissue of the umbilical cord, contain additional stem cells which have been shown to be of great potential for regenerative medicine. Importantly, cord blood is abundant, it can be banked and shipped with ease, and thus has an indisputable potential for future medicines and regenerative therapies. Driven by a massive interest for regenerative medicine and alternative yet ethically acceptable stem cell sources, the scientific literature on umbilical cord and cord blood stem cells has increased tremendously. This book provides a consolidated, up-to-date overview of basic research on hematopoietic and mesenchymal stem cells contained within umbilical cord tissue, as well as other more recently described stem and precursor cells of not yet fully elucidated potential. It also takes an in-depth look at basic and translational research efforts with stem cells from the umbilical cord in academic institutions and biotech companies. Suitable for use as a primer and reference book by medical fellows and researchers entering the research fields of stem cell biology and regenerative medicine, it can also be used by students (undergraduate and graduate) as a starting point for read-up on the literature on stem cells and their potential and applications, or as a teaching tool in graduate schools for biologists, particularly for students wanting to enter the emerging field of stem cell biology.

Cord Blood Book

Cord Blood


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2005-11-26
  • Genre: Medical
  • Pages : 334
  • ISBN 10 : 9780309095860

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Cord Blood Excerpt :

With the potential for self-renewal and differentiation, the possibilities for stem cells are enormous. One specific type of stem cell, the hematopoietic progenitor cell (HPC), which is derived from umbilical cord blood (as well as adult bone marrow and mobilized peripheral blood), holds particular promise. To make the most of these HPCs, the Institute of Medicine was asked to consider the optimal structure for a national cord blood program and to address pertinent issues related to maximizing the potential of stem cell technology. Cord Blood: Establishing a National Hematopoietic Stem Cell Bank Program examines: The role of cord blood in stem cell transplantation The current status of blood banks already in existence The optimal structure for the cord blood program The current use and utility of cord blood for stem cell transplants The best way to advance the use of cord blood units and make them available for research Expert advice from leaders in the fields of economics, public health, medicine, and biostatistics combine to make this very timely and topical book useful to a number of stakeholders.

Vascular Biology of the Placenta Book

Vascular Biology of the Placenta


  • Author : Yuping Wang
  • Publisher : Biota Publishing
  • Release Date : 2017-06-23
  • Genre: Medical
  • Pages : 113
  • ISBN 10 : 9781615047512

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Vascular Biology of the Placenta Excerpt :

The placenta is an organ that connects the developing fetus to the uterine wall, thereby allowing nutrient uptake, waste elimination, and gas exchange via the mother's blood supply. Proper vascular development in the placenta is fundamental to ensuring a healthy fetus and successful pregnancy. This book provides an up-to-date summary and synthesis of knowledge regarding placental vascular biology and discusses the relevance of this vascular bed to the functions of the human placenta.

Stem Cell Banking Book

Stem Cell Banking


  • Author : Dusko Ilic
  • Publisher : Springer
  • Release Date : 2014-05-05
  • Genre: Science
  • Pages : 168
  • ISBN 10 : 9781493905850

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Stem Cell Banking Excerpt :

This book exemplifies experience across the globe in banking of cord blood, mesenchymal, embryonic and induced pluripotent stem cells for clinical use from the United States, Canada, the European Union, Switzerland and Japan to Iran, India and Serbia. The concerns are similar regardless of stem cell type or origin. Implementing core values and common standards depend often on specific circumstances of political and economic setting, which makes flexibility as important as systematic planning. Banking of stem cells is not just building a repository and storing samples. The planning, design, construction and maintenance involve multiple skilled professionals. Stem cell banks are points where technology and medicine converge with ethics, laws and regulations. If properly designed and organized, their utilization will have a broad impact not only on the scientific community and medical professionals but also on the general public.

Regenerative Medicine and Cell Therapy Book

Regenerative Medicine and Cell Therapy


  • Author : Hossein Baharvand
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-08-09
  • Genre: Science
  • Pages : 318
  • ISBN 10 : 9781627030984

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Regenerative Medicine and Cell Therapy Excerpt :

Therapeutic applications within regenerative biomedicine has gained tremendous interest from a growing, multidisciplinary community of investigators in recent years, driven by the hope of finding cures for several diseases. Regenerative Medicine and Cell Therapy discusses cutting-edge science in the field of regenerative biomedicine and its therapeutic applications to various medical disorders. The chapters are written by renowned scientists in the specific fields. This will be a useful book for basic and clinical scientists, especially young investigators and stem cell biology students who are newly entering the world of stem cells research. The editors’ goal is that the new knowledge and research outlined in this book will help contribute to new therapies for a wide variety of diseases that presently afflict humanity.

Progenitor and Stem Cell Technologies and Therapies Book

Progenitor and Stem Cell Technologies and Therapies


  • Author : Anthony Atala
  • Publisher : Elsevier
  • Release Date : 2012-03-15
  • Genre: Medical
  • Pages : 568
  • ISBN 10 : 9780857096074

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Progenitor and Stem Cell Technologies and Therapies Excerpt :

Progenitor and stem cells have the ability to renew themselves and change into a variety of specialised types, making them ideal materials for therapy and regenerative medicine. Progenitor and stem cell technologies and therapies reviews the range of progenitor and stem cells available and their therapeutic application. Part one reviews basic principles for the culture of stem cells before discussing technologies for particular cell types. These include human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells. Part two discusses wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies. The final part of the book considers the therapeutic use of stem and progenitor cells. Chapters review the use of adipose tissue-derived stem cells, umbilical cord blood (UCB) stem cells, bone marrow, auditory and oral cavity stem cells. Other chapters cover the use of stem cells in therapies in various clinical areas, including lung, cartilage, urologic, nerve and cardiac repair. With its distinguished editor and international team of contributors, Progenitor and stem cell technologies and therapies is a standard reference for both those researching in cell and tissue biology and engineering as well as medical practitioners investigating the therapeutic use of this important technology. Reviews the range of progenitor and stem cells available and outlines their therapeutic application Examines the basic principles for the culture of stem cells before discussing technologies for particular cell types, including human embryonic, induced pluripotent, amniotic and placental, cord and multipotent stem cells Includes a discussion of wider issues such as intellectual property, regulation and commercialisation of stem cell technologies and therapies

Stem Cells and the Future of Regenerative Medicine Book

Stem Cells and the Future of Regenerative Medicine


  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2002-01-25
  • Genre: Science
  • Pages : 112
  • ISBN 10 : 0309170427

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Stem Cells and the Future of Regenerative Medicine Excerpt :

Recent scientific breakthroughs, celebrity patient advocates, and conflicting religious beliefs have come together to bring the state of stem cell researchâ€"specifically embryonic stem cell researchâ€"into the political crosshairs. President Bush’s watershed policy statement allows federal funding for embryonic stem cell research but only on a limited number of stem cell lines. Millions of Americans could be affected by the continuing political debate among policymakers and the public. Stem Cells and the Future of Regenerative Medicine provides a deeper exploration of the biological, ethical, and funding questions prompted by the therapeutic potential of undifferentiated human cells. In terms accessible to lay readers, the book summarizes what we know about adult and embryonic stem cells and discusses how to go about the transition from mouse studies to research that has therapeutic implications for people. Perhaps most important, Stem Cells and the Future of Regenerative Medicine also provides an overview of the moral and ethical problems that arise from the use of embryonic stem cells. This timely book compares the impact of public and private research funding and discusses approaches to appropriate research oversight. Based on the insights of leading scientists, ethicists, and other authorities, the book offers authoritative recommendations regarding the use of existing stem cell lines versus new lines in research, the important role of the federal government in this field of research, and other fundamental issues.

Frontiers of Cord Blood Science Book

Frontiers of Cord Blood Science


  • Author : Niranjan Bhattacharya
  • Publisher : Springer Science & Business Media
  • Release Date : 2009-04-21
  • Genre: Medical
  • Pages : 400
  • ISBN 10 : 1848001673

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Frontiers of Cord Blood Science Excerpt :

Cord blood is a significant source of hematopoietic stem and progenitor cells for the treatment of blood and genetic disorders. Cord blood is also an alternative to embryos as a source of tissue for regenerative medicine. Cells from cord blood have been shown to transdifferentiate into nonhematopoietic cells, including those of the brain, heart, liver, pancreas, bone, and cartilage, in tissue culture and in animal systems. Recently it has been demonstrated that both cardiac and glial cell differentiation of cord blood donor cells occurred in recipients of unrelated donor cord blood transplantation as part of a treatment regime for Krabbe disease and Sanfilippo syndrome. These observations raise the possibility that cord blood may serve as a source of cells to facilitate tissue repair and regeneration in the future. CD34 stem cell-rich umbilical cord whole blood transfusion has the potential to have an immediate benefit of better tissue oxygenation with an additional delayed benefit of possible engraftment of umbilical cord stem cells.

Umbilical Cord Stem Cell Therapy Book

Umbilical Cord Stem Cell Therapy


  • Author : David A. Steenblock
  • Publisher : Basic Health Publications, Inc.
  • Release Date : 2006
  • Genre: Health & Fitness
  • Pages : 178
  • ISBN 10 : 159120125X

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Umbilical Cord Stem Cell Therapy Excerpt :

Examines the potential for stem cells gleaned from umbilical cords to generate a wealth of new therapy and healing medicines for neurological conditions and blood problems.

Fetal Stem Cells in Regenerative Medicine Book

Fetal Stem Cells in Regenerative Medicine


  • Author : Dario O. Fauza
  • Publisher : Springer
  • Release Date : 2016-05-02
  • Genre: Science
  • Pages : 453
  • ISBN 10 : 9781493934836

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Fetal Stem Cells in Regenerative Medicine Excerpt :

This book explores the regenerative properties of fetal stem cells, from feto-maternal cell traffic through perinatal stem cells, with a discussion of key topics including stem cell banking, drug screening, in utero stem cell transplantation and ethical considerations. The expertly authored chapters also delve into embryonic, amniotic membrane, and umbilical cord blood stem cells; fetal development models; fetal cell reprogramming; culture methods; disease models; perinatal gene therapy, and more. These chapters are grouped into four sections, each discussing a separate prenatal stem cell population and providing fascinating historical contexts for our knowledge of these systems. Featuring a foreword written by the renowned Dr. Joseph Vacanti of the Harvard Stem Cell Institute, Fetal Stem Cells in Regenerative Medicine: Principles and Translational Strategies is a welcome and timely contribution to the Stem Cell Biology and Regenerative Medicine series. It is essential reading for scientists and researchers, clinicians and residents, and advanced students involved in stem cells, regenerative medicine, tissue engineering, and related disciplines such as embryology.

Adult Stem Cell Therapies  Alternatives to Plasticity Book

Adult Stem Cell Therapies Alternatives to Plasticity


  • Author : Mariusz Z. Ratajczak
  • Publisher : Springer
  • Release Date : 2014-09-10
  • Genre: Science
  • Pages : 266
  • ISBN 10 : 9781493910014

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Adult Stem Cell Therapies Alternatives to Plasticity Excerpt :

This timely volume explores various techniques for tissue and organ regeneration using stem cells isolated from adult tissues. It discusses alternative explanations of stem cell plasticity as well as current clinical results with adult stem cell therapies. It examines the presence of potential pluripotent stem cells in adult tissues, paracrine effects of stem cell therapies, and involvement of exosomes and microparticles into observed phenomena. Fifteen chapters, all written by noted leaders of their fields, focus on a variety of topics including cord blood and hematopoietic stem cells, skin and tissue organ regeneration, very small embryonic-like stem cells, and cell therapies in cardiology, neonatology, and neurology. Edited by Dr. Mariusz Ratajczak, an internationally known specialist in adult stem cell biology, Adult Stem Cell Therapies: Alternatives to Plasticity is an important addition to the Stem Cell Biology and Regenerative Medicine series.

The Regeneration Promise  The Facts behind Stem Cell Therapies Book

The Regeneration Promise The Facts behind Stem Cell Therapies


  • Author : Peter Hollands
  • Publisher : Bentham Science Publishers
  • Release Date : 2020-12-03
  • Genre: Health & Fitness
  • Pages : 126
  • ISBN 10 : 9789811482113

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The Regeneration Promise The Facts behind Stem Cell Therapies Excerpt :

The Regeneration Promise is a reader-friendly guide to the world of regenerative medicine and stem cell technology. It covers the history of stem cell technology as a general introduction to the subject and then continues with a description of the many known types of stem cells and how these can potentially be used to treat disease. The author explains the pros and cons of using stem cell technology to treat patients in simple and factual terms throughout the book while clarifying many stem cell myths. There is valuable advice for people considering undergoing stem cell therapy and also for those who are considering stem cell storage such as umbilical cord blood storage at the birth of a baby. The book also covers information on current research in stem cell technology and how this may be useful in the clinic, as promising regenerative medicine treatments emerge in the near future. The simple use of language with a clear explanation of scientific terms, where applicable, makes this book an accessible source of information for anyone interested in enhancing their general knowledge about regenerative medicine when considering such treatment options and understanding the debate surrounding stem cell technology and its use in disease therapy.

Perinatal Stem Cells Book

Perinatal Stem Cells


  • Author : Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2018-06-14
  • Genre: Science
  • Pages : 418
  • ISBN 10 : 9780128120637

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Perinatal Stem Cells Excerpt :

Perinatal Stem Cells provides researchers and clinicians with a comprehensive description of the current clinical and pre-clinical applications of stem cells derived from perinatal sources, such as amniotic fluid, placenta and placental membranes, the umbilical cord and Wharton’s jelly. It's compiled by leading experts in the field, offering readers detailed insights into sources of perinatal stem cells and their potential for disease treatment. Therapeutic applications of perinatal stem cells include the treatment of in utero and pregnancy related diseases, cardiac disease, liver disease, pulmonary disease, inflammatory diseases, for hematopoietic regeneration, and for neural protection after stroke or traumatic brain injury. In addition, the rapid advance in clinical translation and commercialization of perinatal stem cell therapies is highlighted in a section on Clinical and Industry Perspective which provides insight into the new opportunities and challenges involved in this novel and exciting industry. Explores current clinical and pre-clinical application of stem cells derived from perinatal sources Offers detailed insight into sources of perinatal stem cells and their potential for disease treatment Discusses progress in the manufacturing, banking and clinical translation of perinatal stem cells Edited by a world-renowned team to present a complete story of the development and promise of perinatal stem cells