CRISPR Genome Surgery in Stem Cells and Disease Tissues Book

CRISPR Genome Surgery in Stem Cells and Disease Tissues


  • Author : Stephen H. Tsang
  • Publisher : Elsevier
  • Release Date : 2021-10-19
  • Genre: Science
  • Pages : 136
  • ISBN 10 : 9780128178768

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CRISPR Genome Surgery in Stem Cells and Disease Tissues Excerpt :

CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature. Provides a thorough review of CRISPR-Cas9, from discovery to therapy Covers the latest advances in gene editing and its translational applications to various diseases Written by global leaders in the fields of gene editing and stem cell therapy

CRISPR Genome Surgery in Stem Cells and Disease Tissues Book

CRISPR Genome Surgery in Stem Cells and Disease Tissues


  • Author : Stephen H. Tsang
  • Publisher : Academic Press
  • Release Date : 2021-10-20
  • Genre: Science
  • Pages : 136
  • ISBN 10 : 9780128178775

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CRISPR Genome Surgery in Stem Cells and Disease Tissues Excerpt :

CRISPR Genome Surgery in Stem Cells and Disease Tissues focuses uniquely on the clinical applications of CRISPR/Cas9 based technology. Topics include the latest advances in gene editing and its translational applications to various diseases, including retinal degenerative disease, recessively inherited diseases, and dominantly inherited diseases, to name a few. The book's target audience includes researchers, students, clinicians and the general public. This space that is not currently served by any existing resource, so this publication fills a gap in current literature. Provides a thorough review of CRISPR-Cas9, from discovery to therapy Covers the latest advances in gene editing and its translational applications to various diseases Written by global leaders in the fields of gene editing and stem cell therapy

Success in Academic Surgery  Basic Science Book

Success in Academic Surgery Basic Science


  • Author : Gregory Kennedy
  • Publisher : Springer
  • Release Date : 2019-04-29
  • Genre: Medical
  • Pages : 252
  • ISBN 10 : 9783030146443

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Success in Academic Surgery Basic Science Excerpt :

This updated volume provides the foundation for starting a basic science research career as an academic surgeon. Taking a practical approach, the book covers the suggested timeline for the initial academic appointment, including how to setup and fund the laboratory and identifying appropriate scientific mentors and lab personnel. It also describes the application of basic and advanced research techniques, including animal models, flow cytometry, gene editing, tissue engineering, and microbiome analysis. Success in Academic Surgery: Basic Science aims to give guidance on the application of basic and advanced techniques in surgical research. This book is relevant to senior residents and fellows approaching their first academic appointment, as well as more senior investigators interested in expanding their research horizons.

Human Genome Editing Book

Human Genome Editing


  • Author : National Academies of Sciences, Engineering, and Medicine
  • Publisher : National Academies Press
  • Release Date : 2017-08-13
  • Genre: Medical
  • Pages : 329
  • ISBN 10 : 9780309452885

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Human Genome Editing Excerpt :

Genome editing is a powerful new tool for making precise alterations to an organism's genetic material. Recent scientific advances have made genome editing more efficient, precise, and flexible than ever before. These advances have spurred an explosion of interest from around the globe in the possible ways in which genome editing can improve human health. The speed at which these technologies are being developed and applied has led many policymakers and stakeholders to express concern about whether appropriate systems are in place to govern these technologies and how and when the public should be engaged in these decisions. Human Genome Editing considers important questions about the human application of genome editing including: balancing potential benefits with unintended risks, governing the use of genome editing, incorporating societal values into clinical applications and policy decisions, and respecting the inevitable differences across nations and cultures that will shape how and whether to use these new technologies. This report proposes criteria for heritable germline editing, provides conclusions on the crucial need for public education and engagement, and presents 7 general principles for the governance of human genome editing.

CRISPR Cas Systems Book

CRISPR Cas Systems


  • Author : Rodolphe Barrangou
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-13
  • Genre: Science
  • Pages : 302
  • ISBN 10 : 9783642346576

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CRISPR Cas Systems Excerpt :

CRISPR/Cas is a recently described defense system that protects bacteria and archaea against invasion by mobile genetic elements such as viruses and plasmids. A wide spectrum of distinct CRISPR/Cas systems has been identified in at least half of the available prokaryotic genomes. On-going structural and functional analyses have resulted in a far greater insight into the functions and possible applications of these systems, although many secrets remain to be discovered. In this book, experts summarize the state of the art in this exciting field.

Genome Editing and Engineering Book

Genome Editing and Engineering


  • Author : Krishnarao Appasani
  • Publisher : Cambridge University Press
  • Release Date : 2018-08-23
  • Genre: Science
  • Pages : 535
  • ISBN 10 : 9781107170377

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Genome Editing and Engineering Excerpt :

A complete guide to endonuclease-based genomic engineering, from basic science to application in disease biology and clinical treatment.

Precision Medicine  CRISPR  and Genome Engineering Book

Precision Medicine CRISPR and Genome Engineering


  • Author : Stephen H. Tsang
  • Publisher : Springer
  • Release Date : 2017-11-11
  • Genre: Science
  • Pages : 178
  • ISBN 10 : 9783319639048

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Precision Medicine CRISPR and Genome Engineering Excerpt :

This book presents descriptive overviews of gene editing strategies across multiple species while also offering in-depth insight on complex cases of application in the field of tissue engineering and regenerative medicine. Chapters feature contributions from leaders in stem cell therapy and biology, providing a comprehensive view of the application of gene therapy in numerous fields with an emphasis on ophthalmology, stem cells, and agriculture. The book also highlights recent major technological advances, including ZFN, TALEN, and CRISPR. Precision Medicine, CRISPR, and Genome Engineering is part of the highly successful Advances in Experimental Medicine and Biology series. It is an indispensable resource for researchers and students in genetics as well as clinicians.

Retinal Degenerative Diseases Book

Retinal Degenerative Diseases


  • Author : Matthew M. LaVail
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-12-21
  • Genre: Medical
  • Pages : 864
  • ISBN 10 : 9781461406310

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Retinal Degenerative Diseases Excerpt :

This book will contain the proceedings of the XIV International Symposium on Retinal Degeneration (RD2010), held July 13-17, 2010, in Mont-Tremblant, Quebec, Canada. The volume will present representative state-of-the-art research in almost all areas of retinal degenerations, ranging from cytopathologic, physiologic, diagnostic and clinical aspects; animal models; mechanisms of cell death; candidate genes, cloning, mapping and other aspects of molecular genetics; and developing potential therapeutic measures such as gene therapy and neuroprotective agents for potential pharmaceutical therapy.

CRISPR Cas Enzymes Book

CRISPR Cas Enzymes


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2019-01-25
  • Genre: Science
  • Pages : 451
  • ISBN 10 : 9780128167618

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CRISPR Cas Enzymes Excerpt :

CRISPR-Cas Enzymes, Volume 616, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Topics covered in this release include CRISPR bioinformatics, A method for one-step assembly of Class 2 CRISPR arrays, Biochemical reconstitution and structural analysis of ribonucleoprotein complexes in Type I-E CRISPR-Cas systems, Mechanistic dissection of the CRISPR interference pathway in Type I-E CRISPR-Cas system, Site-specific fluorescent labeling of individual proteins within CRISPR complexes, Fluorescence-based methods for measuring target interference by CRISPR-Cas systems, Native State Structural Characterization of CRISRP Associated Complexes using Mass Spectrometry, and more. Provides the authority and expertise of leading contributors from an international board of authors Presents the latest release in the Methods in Enzymology series Updated release includes the latest information on the CRISPR-Cas Enzymes

Plastic Surgery   Principles and Practice E Book Book

Plastic Surgery Principles and Practice E Book


  • Author : Rostam Farhadieh
  • Publisher : Elsevier Health Sciences
  • Release Date : 2021-04-22
  • Genre: Medical
  • Pages : 924
  • ISBN 10 : 9780323653824

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Plastic Surgery Principles and Practice E Book Excerpt :

With detailed, expert guidance on each essential topic, Plastic Surgery: Principles and Practice offers single-volume convenience without sacrificing complete coverage of this multi-faceted field. Written by global leading authorities, it provides concise, easy-to-follow instruction with the clinical details and supportive data needed to achieve optimal patient outcomes. Offers thorough coverage of facelift procedures, rhinoplasty, otoplasty and more, along with clinical pearls from masters in the field. Features hundreds of high-quality images including anatomical line art, case photos, and procedural operative photos. I Includes a superb selection of procedural videos of global experts performing key techniques within operating room and close-up clinical pearls. An ideal resource for residents, fellows, and practitioners in plastic surgery, as well as those in otolaryngology, vascular surgery, and cosmetic dermatology.

Heritable Human Genome Editing Book

Heritable Human Genome Editing


  • Author : The Royal Society
  • Publisher : National Academies Press
  • Release Date : 2021-01-16
  • Genre: Medical
  • Pages : 239
  • ISBN 10 : 9780309671132

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Heritable Human Genome Editing Excerpt :

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Cells Are the New Cure Book
Score: 4
From 1 Ratings

Cells Are the New Cure


  • Author : Robin L. Smith
  • Publisher : BenBella Books
  • Release Date : 2017-10-24
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9781944648848

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Cells Are the New Cure Excerpt :

The future of medicine is happening now. Revolutionary new science is providing cures that were considered science fiction just a few years ago—and not with pills, surgery, or radiation, but with human cells. Promising treatments now in extensive clinical trials could have dramatic impacts on cancer, autoimmune diseases, organ replacement, heart disease, and even aging itself. The key to these breakthroughs is the use of living cells as medicine instead of traditional drugs. Discover the advances that are alleviating the effects of strokes, Alzheimer's disease, and even allergies. Cells Are the New Cure takes you into the world of regenerative medicine, which enables doctors to repair injured and aging tissues and even create artificial body parts and organs in the lab. Cellular medicine experts Robin L. Smith, MD, and Max Gomez, PhD, outline the new technologies that make it possible to harness the immune system to fight cancer and reverse autoimmune diseases like multiple sclerosis, type 1 diabetes, and rheumatoid arthritis. CRISPR, a new technology for targeted gene editing, promises to eradicate genetic diseases, allowing us to live longer lives—possibly even beyond age 100 in good health. Cells Are the New Cure takes you on a tour of the most exciting and cutting-edge developments in medicine. The content inside these pages could save your life or the life of someone you love.

Stem Cells for Cancer and Genetic Disease Treatment Book

Stem Cells for Cancer and Genetic Disease Treatment


  • Author : Phuc Van Pham
  • Publisher : Springer
  • Release Date : 2018-11-07
  • Genre: Science
  • Pages : 190
  • ISBN 10 : 9783319980652

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Stem Cells for Cancer and Genetic Disease Treatment Excerpt :

This invaluable resource discusses insights ranging from basic biological mechanisms of various types of stem cells through the potential applications in the treatment of human diseases, including cancer and genetic disorders. These discoveries are placed within the structural context of tissue and developmental biology in sections dealing with recent advances in understanding different types of stem cell biology and their potential applications in tissue repair and regeneration and in the treatment different types of human cancer and genetic diseases or disorders. Stem Cells for Cancer and Genetic Disease Treatment and the other books in the Stem Cells in Clinical Applicationsseries will be invaluable to scientists, researchers, advanced students and clinicians working in stem cells, regenerative medicine or tissue engineering as well as cancer or genetics research.

Advances in Genome Editing Book

Advances in Genome Editing


  • Author : Jennifer A. Doudna
  • Publisher : Unknown
  • Release Date : 2016
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 1618962337

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Advances in Genome Editing Excerpt :