Cytoskeleton and Small G Proteins Book

Cytoskeleton and Small G Proteins


  • Author : Philippe Jeanteur
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Science
  • Pages : 234
  • ISBN 10 : 9783642585913

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Cytoskeleton and Small G Proteins Excerpt :

The internal structure of a cell can be affected by signals in the form of small molecules outside the cell. These changes can then alter the shape or adhesiveness of the cell. This volume centers particularly on one family of cellular proteins which transmit these signals, the Rho Ras-like GTPases, and examines their role in normal cellular processes and development. Also discussed are their roles in cancer formation and microbial pathogenesis.

Cytoskeleton Book

Cytoskeleton


  • Author : Jose C. Jimenez-Lopez
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-05-17
  • Genre: Science
  • Pages : 342
  • ISBN 10 : 9789535131694

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Cytoskeleton Excerpt :

The cytoskeleton is a highly dynamic intracellular platform constituted by a three-dimensional network of proteins responsible for key cellular roles as structure and shape, cell growth and development, and offering to the cell with "motility" that being the ability of the entire cell to move and for material to be moved within the cell in a regulated fashion (vesicle trafficking). The present edition of Cytoskeleton provides new insights into the structure-functional features, dynamics, and cytoskeleton's relationship to diseases. The authors' contribution in this book will be of substantial importance to a wide audience such as clinicians, researches, educators, and students interested in getting updated knowledge about molecular basis of cytoskeleton, such as regulation of cell vital processes by actin-binding proteins as cell morphogenesis, motility, their implications in cell signaling, as well as strategies for clinical trial and alternative therapies based in multitargeting molecules to tackle diseases, that is, cancer.

Molecular Biology of the Cell Book
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Molecular Biology of the Cell


  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 0815332181

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Molecular Biology of the Cell Excerpt :

Ras Superfamily Small G Proteins  Biology and Mechanisms 1 Book

Ras Superfamily Small G Proteins Biology and Mechanisms 1


  • Author : Alfred Wittinghofer
  • Publisher : Springer
  • Release Date : 2014-09-22
  • Genre: Science
  • Pages : 445
  • ISBN 10 : 9783709118061

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Ras Superfamily Small G Proteins Biology and Mechanisms 1 Excerpt :

This first of two volumes provides a general overview of the genetics, structure, mechanism and regulation of the Ras superfamily proteins and describes in detail the signaling pathways and processes regulated by specific members of this family. The focus of this first volume is on the Rho and Ras subfamily of small G proteins. Renowned scientists provide insights into the biochemistry of the classical and non-classical small G-protein family members, their spatio-temporal regulation, their effectors and their roles in health and disease. Together with Volume 2, this book provides a comprehensive and state-of-the-art work on small G-proteins (GTPases). It is intended for graduates and professors in biochemistry and cell biology already working on small G-proteins (small GTPases), but also offers an extremely valuable resource for those readers who are new to the field.

Small Rho Gtpases   F Actin Cytoskeleton During Mammalian Cell Swelling Book

Small Rho Gtpases F Actin Cytoskeleton During Mammalian Cell Swelling


  • Author : Iris Carton
  • Publisher : Leuven University Press
  • Release Date : 2003-09
  • Genre: Science
  • Pages : 110
  • ISBN 10 : 9058672948

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Small Rho Gtpases F Actin Cytoskeleton During Mammalian Cell Swelling Excerpt :

"Volume regulation in animal cells, Actin Cytoskeleton, RHO GTPases, Involvement of the RHO/RHO Kinase Pathway in the Activation of VRAC in CPAE cells, Role of small GTPases in the swelling-induced F-actin reorganization in Rat-1 Fibroblasts, Tyrosine Phosphorylation in Caveolae-enriched fractions of Rat-1 fibroblasts, Cell culture and transfection, Solutions, Chemicals and agents, Purification of Caveolae, SDS-PAGE and immunochemical analysis of proteins, Staining of the Cytoskeleton Quantification of F-Actin, Immunoflorescence, Rho/Rho Kinase cascade has a modulatory role in the activation of VRAC in CPAE cells, Reorganization of the F-Actin Cytoskeleton in Rat-1 fibroblasts, Tyrosine Phosphorylation in lipid rafts of Rat-1 fibroblasts during cell swelling, Summary."

Cumulated Index Medicus Book

Cumulated Index Medicus


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1997
  • Genre: Medicine
  • Pages : null
  • ISBN 10 : UIUC:30112001088449

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Cumulated Index Medicus Excerpt :

Phagocytosis  The Host Book

Phagocytosis The Host


  • Author : S. Gordon
  • Publisher : Elsevier
  • Release Date : 1999-11-22
  • Genre: Science
  • Pages : 521
  • ISBN 10 : 0080526101

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Phagocytosis The Host Excerpt :

An accompanying volume (Volume 6) in this series presents strategies of cellular invasion from the viewpoint of the microbe. This filed of study is growing rapidly after a somewhat slow start over recent decades. This collection of invited chapters attempts to reflect current research, and brings together cell biologists, microbiologists and immunologists with disparate interests. However, there is a certain unity, even repetition of key themes, hopefully like a symphony rather than a boring catalogue. It will be evident that editorial bias favors intracellular paratism and medically important organisms. The neutrophil is far more than a supporting player to the macrophage, and some attempt is made to remind the reader of some of its unique skills. To retain a manageable size, the emphasis is on relatively early events such as mutual recognition, cell entry, and response, rather than on longterm changes in gene expression by either host cell or pathogen. Viruses are excluded not because of lack of importance but because of somewhat different research approaches, although it is cytogenes, share common strategies in invasion and intercellular spread.

Intracellular Mechanisms for Neuritogenesis Book

Intracellular Mechanisms for Neuritogenesis


  • Author : Ivan Curtis
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-04-03
  • Genre: Medical
  • Pages : 333
  • ISBN 10 : 9780387685618

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Intracellular Mechanisms for Neuritogenesis Excerpt :

This book present in novel, distinct, but highly related aspects of the intracellular mechanisms required for the formation of a functional neurite, which include cytoskeletal organization, membrane traffic, and signal transduction. Its aim is to present this topic to the general readership of neurobiologists and molecular and cellular biologists to further stimulate the interest into this exciting section of neurobiology.

The Biochemistry of Cell Signalling Book

The Biochemistry of Cell Signalling


  • Author : Ernst J. M. Helmreich
  • Publisher : Oxford University Press, USA
  • Release Date : 2001
  • Genre: Science
  • Pages : 328
  • ISBN 10 : 0198508204

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The Biochemistry of Cell Signalling Excerpt :

The Biochemistry of Cell Signalling is a comprehensive yet concise study of the principles of cell signalling, concentrating on the structural and mechanistic aspects.

Bacterial Protein Toxins Book

Bacterial Protein Toxins


  • Author : Alistair J. Lax
  • Publisher : Cambridge University Press
  • Release Date : 2005-01-10
  • Genre: Science
  • Pages : null
  • ISBN 10 : 1139443593

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Bacterial Protein Toxins Excerpt :

Bacterial toxins that act inside cells interact very specifically with key components of the cell and some even manipulate the cell in subtle ways for their own purposes. These potent toxins, described in this 2005 book, will be of interest to both microbiologists and cell biologists. Some of these toxins are conventional multidomain toxins that are self-programmed to enter cells. Others are delivered by type III mechanisms, often as a package of potent molecules. The molecular targets for all these toxins mediate signal transduction and the cell cycle to regulate the crucial processes of cell growth, cell division and differentiation. Thus these potent toxins are not only responsible for disease, but also provide a powerful set of tools with which to interrogate the biology of the cell. In addition such toxins may act directly to promote carcinogenesis and hence their study is also of interest in a wider context.

Signaling and the Cytoskeleton Book

Signaling and the Cytoskeleton


  • Author : Kermit L. Carraway
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-09
  • Genre: Science
  • Pages : 286
  • ISBN 10 : 9783662129937

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Signaling and the Cytoskeleton Excerpt :

This monograph explores the relationships between cell signaling and the cytoplasmic cytoskeleton in fundamental cell processes, thus bridging the gap between two very active aspects of molecular cell biology. It covers the two main - and reciprocal - questions of these relationships: How are structure and function of the cytoskeleton affected by external signals which impinge on the cell? How does the cytoskeleton influence the cellular signaling processes which determine cell behavior?

G Proteins  Cytoskeleton  and Cancer Book

G Proteins Cytoskeleton and Cancer


  • Author : Hiroshi Maruta
  • Publisher : R G Landes Company
  • Release Date : 1998
  • Genre: Medical
  • Pages : 377
  • ISBN 10 : NWU:35558004225864

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G Proteins Cytoskeleton and Cancer Excerpt :

Building upon the pioneering work of Klaus Weber, who in the 1970s discovered a key to the malignant transformation of normal cells by tumor virus infection or mutations via the disruption of actin cables and subsequent induction of membrane ruffling occurring with oncogenes such as v-Ras and v-Src, the global contributors aim toward the quantum leap of creating an anticancer Holy Grail that would attenuate the malignant activity of oncogenic mutants. The two dozen papers are organized under the four major headings of: actin-cytoskeleton, Ras/Rho family GTPases, links between G proteins and actin, and new anticancer drugs (e.g. farnesyltransferase inhibitors, SCH51344, and azatyrosine). Annotation copyrighted by Book News, Inc., Portland, OR

Cytoskeleton  Signalling and Cell Regulation Book

Cytoskeleton Signalling and Cell Regulation


  • Author : Kermit Carraway
  • Publisher : OUP Oxford
  • Release Date : 1999-12-16
  • Genre: Science
  • Pages : 308
  • ISBN 10 : 9780191565991

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Cytoskeleton Signalling and Cell Regulation Excerpt :

This book provides descriptions of experimental methods in research on the cytoskeleton and its relationships to signaling and cell regulation. Thus, it bridges two active and fertile areas of research. The focus is directed particularly towards methods which take advantage of recent advances in molecular biology, microscopy and immunological assays. A second emphasis is on methods for understanding dynamic changes in cells. A third emphasis is on the formation and turnover of macromolecular and supramolecular complexes, which are so important in driving cell regulation and the behaviour of cytoskeletal elements. A combination of practical advice and detailed protocols should make this book valuable for both novice and experienced workers in these burgeoning fields.

G Protein Coupled Receptors Book

G Protein Coupled Receptors


  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2016-02-26
  • Genre: Science
  • Pages : 502
  • ISBN 10 : 9780128036129

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G Protein Coupled Receptors Excerpt :

G-Protein-Coupled Receptors: Signaling, Trafficking, and Regulation, a new volume in the Methods in Cell Biology series continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers research methods in G-Protein-Coupled Receptors, and includes sections on such topics signaling, trafficking and regulation. Covers the increasingly appreciated cell biology field of G-protein-coupled receptors Includes both established and new technologies Contributed by experts in the field Covers topics such as signaling, trafficking, and regulation