Detection Methods in Precision Medicine Book

Detection Methods in Precision Medicine


  • Author : Mengsu Yang
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-12-14
  • Genre: Science
  • Pages : 370
  • ISBN 10 : 9781788017619

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Detection Methods in Precision Medicine Excerpt :

This book will be among the first to cover the detection methods for precision medicine that are set to transform health care in the future.

Detection Methods in Precision Medicine Book

Detection Methods in Precision Medicine


  • Author : Mengsu (Michael) Yang
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-12-10
  • Genre: Science
  • Pages : 370
  • ISBN 10 : 9781788019965

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Detection Methods in Precision Medicine Excerpt :

Precision medicine is a topical subject that attracts tremendous attention from scientific and medical communities, being set to transform health care in the future. This book will be among the first to cover the detection methods for precision medicine. The first section provides an overview of the biomarkers used for precision medicine, such as proteins, nucleic acids, and metabolites. The coverage then turns to sequencing techniques and their applications, and other bioanalytical techniques, including mass spectrometry for proteome and phosphoproteome analysis, immunological methods and droplet technologies. The final sections include biosensors applied to precision medicine and clinical applications. This book provides a reference for researchers and students interested and working in the development of bioanalytical techniques for clinical applications. It provides a useful introduction for physicians and medical laboratory technologists to the recent advances in detection methods for precision medicine.

Companion Diagnostics  CDx  in Precision Medicine Book

Companion Diagnostics CDx in Precision Medicine


  • Author : Il-Jin Kim
  • Publisher : CRC Press
  • Release Date : 2019-03-06
  • Genre: Computers
  • Pages : 256
  • ISBN 10 : 9781000007213

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Companion Diagnostics CDx in Precision Medicine Excerpt :

There is a new trend in anti-cancer therapeutics development: a targeted therapy and precision medicine that targets a subgroup of patients with specific biomarkers. An in vitro diagnostic (IVD) assay is required to identify a subgroup of cancer patients who would benefit from the targeted therapy, or not likely benefit, or have a high risk of side effects from the specific drug treatment. This IVD or medical device is called a companion diagnostic (CDx) assay. It is key to have a robust CDx assay or device for the success of targeted therapy and precision medicine. This book covers the technical, historical, clinical, and regulatory aspects of CDx in precision medicine. Clearly, more and more newly developed oncology drugs will require accompanying CDx assays, and this book, with chapters contributed by renowned oncologists, provides a comprehensive foundation for the knowledge and application of CDx for precision medicine.

Precision Medicine Book

Precision Medicine


  • Author : Hans-Peter Deigner
  • Publisher : Academic Press
  • Release Date : 2018-02-15
  • Genre: Medical
  • Pages : 374
  • ISBN 10 : 9780128054338

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Precision Medicine Excerpt :

Precision Medicine: Tools and Quantitative Approaches discusses precision and personalized medicine, two relevant topics that are revolutionizing diagnostics and treatment, while also providing a shift toward prevention. The book covers the most relevant features and explanations underlying developments in the field. A timely review on prerequisites, causes and consequences is given. Unique to this book is a combined view on technical and data analysis aspects that is mandatory for obtaining and interpreting results. This book is a valuable source for researchers in medical and life sciences, physicians and students with an interest in this emerging field of precision medicine. Provides technological aspects in precision medicine with aspects of modern statistical and bioinformatics models and methods Brings timely reviews on status and chances in precision medicine and associated aspects of data analysis, statistics and data interpretation Encompasses easy access to relevant approaches, interactions and original literature

Pharmacogenomics and Precision Medicine  An Issue of the Clinics in Laboratory Medicine  E Book Book

Pharmacogenomics and Precision Medicine An Issue of the Clinics in Laboratory Medicine E Book


  • Author : Kristen Reynolds
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-08-16
  • Genre: Medical
  • Pages : 177
  • ISBN 10 : 9780323462808

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Pharmacogenomics and Precision Medicine An Issue of the Clinics in Laboratory Medicine E Book Excerpt :

This issue of the Clinics in Laboratory Medicine on “Pharmacogenomics is being edited by Drs. Roland Valdes and Kristen Reynolds and will cover a wide variety of topics, including but not limited to, fundamentals of pharmacology, a review of pharmacogenetics guidelines, pharmacogenetic testing in pain management, pharmacogenetics of pain management, clinical and economic impact of pharmacogenetic genotyping analysis, exosome analysis in lab medicine, and implementation of pharmacogenetics in developing countries.

Gastric Cancer In The Precision Medicine Era Book

Gastric Cancer In The Precision Medicine Era


  • Author : Vincenzo Canzonieri
  • Publisher : Springer
  • Release Date : 2019-05-02
  • Genre: Medical
  • Pages : 256
  • ISBN 10 : 9783030048617

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Gastric Cancer In The Precision Medicine Era Excerpt :

Gastric cancer is one of the most common and potentially lethal gastrointestinal malignancy, but it is now at the forefront of modern oncology due to new discoveries. In recent years, the field of gastric cancer has been transformed by many notable developments in both the diagnostic area and the therapeutic strategies. The main aim of the text is to propose a comprehensive, state-of-the art review of this field, and will serve as a valuable resource for oncologists, pathologists, surgeons and researchers with an interest in gastric cancer. The first chapters will review the interplay between pathogens and especially H. pylori, inflammation, genomic instability, and tumorigenesis. Secondly, an exhaustive overview of the diagnosis of gastric cancer from a clinical/endoscopic and pathologic perspectives will be illustrated. Two specific chapters will deal with tissue and serum biomarkers with an important role in diagnosis as well as prognostic and predictive markers of response to specific therapy. A central section of the book will focus on treatment options available today for patients. Surgery is the cornerstone of treatment for gastric cancer; however, the prognosis of patients with locally advanced disease is still poor even after curative resection. Therefore, in order to improve the prognosis of patients, especially with advanced stage, a multimodal strategy is advisable and is thoroughly addressed in the appropriate section. With the advent of next-generation sequencing and new preclinical model technologies, the genomic landscape of gastric cancer has been delineated and molecular characterizations finalized to novel therapeutic targets of each molecular subtype have been identified. These advances are making it feasible to integrate clinical and phenotype-based diagnostic and therapeutic methods and are described in a dedicated section. The text will conclude with chapters focusing on the future direction of gastric cancer research in the precision medicine

Pharmacogenomics in Precision Medicine Book

Pharmacogenomics in Precision Medicine


  • Author : Weimin Cai
  • Publisher : Springer Nature
  • Release Date : 2020-06-12
  • Genre: Medical
  • Pages : 289
  • ISBN 10 : 9789811538957

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Pharmacogenomics in Precision Medicine Excerpt :

This book provides an introduction to the principles of pharmacogenomics and precision medicine, followed by the pharmacogenomics aspects of major therapeutic areas such as cardiovascular disease, cancer, organ transplantation, psychiatry, infection, antithrombotic drugs. It also includes genotyping technology and therapeutic drug monitoring in Pharmacogenomics; ethical, Legal and Regulatory Issues; cost-effectiveness of pharmacogenetics-guided treatment; application of pharmacogenomics in drug discovery and development and clinical Implementation of Pharmacogenomics for Personalized Precision Medicine. The contributors of Pharmacogenomics in Precision Medicine come from a team of experts, including professors from academic institutions and practitioner from hospital. It will give an in-depth overview of the current state of pharmacogenomics in drug therapy for all health care professionals and graduate students in the era of precision medicine.

Genomic and Precision Medicine Book

Genomic and Precision Medicine


  • Author : Geoffrey S. Ginsburg
  • Publisher : Academic Press
  • Release Date : 2017-03-30
  • Genre: Science
  • Pages : 370
  • ISBN 10 : 9780128006542

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Genomic and Precision Medicine Excerpt :

Genomic and Precision Medicine: Primary Care, Third Edition is an invaluable resource on the state-of-the-art tools, technologies and policy issues that are required to fully realize personalized health care in the area of primary care. One of the major areas where genomic and personalized medicine is most active is the realm of the primary care practitioner. Risk, family history, personal genomics and pharmacogenomics are becoming increasingly important to the PCP and their patients, and this book discusses the implications as they relate to primary care practitioners. Presents a comprehensive volume for primary care providers Provides succinct commentary and key learning points that will assist providers with their local needs for the implementation of genomic and personalized medicine Includes a current overview on major opportunities for genomic and personalized medicine in practice Highlights case studies that illustrate the practical use of genomics in the management in patients

Precision Medicine for Investigators  Practitioners and Providers Book

Precision Medicine for Investigators Practitioners and Providers


  • Author : Joel Faintuch
  • Publisher : Academic Press
  • Release Date : 2019-11-16
  • Genre: Science
  • Pages : 640
  • ISBN 10 : 9780128191798

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Precision Medicine for Investigators Practitioners and Providers Excerpt :

Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included. Provides a three-pronged approach to precision medicine that is focused on investigators, practitioners and healthcare providers Covers disease groups and ancillary information about techniques, resources and consequences Follows a structured blueprint, ensuring essential chapters items are not overlooked

Precision Medicine in Cancers and Non Communicable Diseases Book

Precision Medicine in Cancers and Non Communicable Diseases


  • Author : Debmalya Barh
  • Publisher : CRC Press
  • Release Date : 2018-09-03
  • Genre: Medical
  • Pages : 326
  • ISBN 10 : 9781351650786

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Precision Medicine in Cancers and Non Communicable Diseases Excerpt :

The availability of human genome, large amount of data on individual genetic variations, environmental interactions, influence of lifestyle, and cutting-edge tools and technologies for big-data analysis have led to the era of clinical practice of "Precision Medicine". This book aims to provide a readily available resource on all the important developments achieved so far in the field of oncology. All recent developments have been explained along with epidemiology, technologies and approaches to manage the included diseases. Therefore, readers will get the up to date information on the next-generation approach in tackling all kinds of cancer. Key Features • Presents the latest trend of cancer management based on precision/predictive medicine approach • Reviews the latest and up to date literature in the field of Precision Medicine • Highlights the next generation approach in tackling malignant diseases • Discusses how a life-threatening disease like cancer can be managed with the help of Precision Medicine • Encapsulates a global prospective

A Theranostic and Precision Medicine Approach for Female Specific Cancers Book

A Theranostic and Precision Medicine Approach for Female Specific Cancers


  • Author : Rama Rao Malla
  • Publisher : Academic Press
  • Release Date : 2020-11-06
  • Genre: Science
  • Pages : 318
  • ISBN 10 : 9780128226926

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A Theranostic and Precision Medicine Approach for Female Specific Cancers Excerpt :

A Theranostic and Precision Medicine Approach for Female-Specific Cancers provides information regarding ongoing research and clinical data surrounding female specific cancers (breast, cervical, ovarian and endometrial cancers). The book encompasses detailed descriptions about diagnostics and therapeutic options for easy understanding, focusing on the subject matter with a broader range of treatment options. In addition, it explores new theranostics, i.e., diagnostic, therapeutic and precision medicine strategies currently being developed for FSCs. This book is a valuable resource for cancer researchers, clinicians, graduate students and other members of biomedical field who need to understand the most recent and promising approaches to manage FSCs. Explores new diagnostic biomarkers surrounding the early detection and prognosis of FSCs Examines new genetic and molecularly targeted approaches for the treatment of these aggressive diseases Discusses new theranostic approaches that combine diagnosis and treatment through the use of nanotechnology in FSCs Addresses how these various advances can be integrated into a precision and personalized medicine approach that can eventually enhance patient care

Artificial Intelligence for Drug Development  Precision Medicine  and Healthcare Book

Artificial Intelligence for Drug Development Precision Medicine and Healthcare


  • Author : Mark Chang
  • Publisher : CRC Press
  • Release Date : 2020-05-07
  • Genre: Business & Economics
  • Pages : 352
  • ISBN 10 : 9781000766721

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Artificial Intelligence for Drug Development Precision Medicine and Healthcare Excerpt :

Artificial Intelligence for Drug Development, Precision Medicine, and Healthcare covers exciting developments at the intersection of computer science and statistics. While much of machine-learning is statistics-based, achievements in deep learning for image and language processing rely on computer science’s use of big data. Aimed at those with a statistical background who want to use their strengths in pursuing AI research, the book: · Covers broad AI topics in drug development, precision medicine, and healthcare. · Elaborates on supervised, unsupervised, reinforcement, and evolutionary learning methods. · Introduces the similarity principle and related AI methods for both big and small data problems. · Offers a balance of statistical and algorithm-based approaches to AI. · Provides examples and real-world applications with hands-on R code. · Suggests the path forward for AI in medicine and artificial general intelligence. As well as covering the history of AI and the innovative ideas, methodologies and software implementation of the field, the book offers a comprehensive review of AI applications in medical sciences. In addition, readers will benefit from hands on exercises, with included R code.

Precision Medicine in Oncology Book

Precision Medicine in Oncology


  • Author : Angela Re
  • Publisher : Frontiers Media SA
  • Release Date : 2019-01-21
  • Genre: Uncategoriezed
  • Pages : 163
  • ISBN 10 : 9782889457052

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Precision Medicine in Oncology Excerpt :

The emerging precision medicine approach aims to tailor disease prevention and treatment to each patient on the basis of individual variability, environmental factors and lifestyle. Fundamental achievements in the last few decades have converged to offer nowadays the compelling opportunity to move towards this innovative approach: i) unprecedented improvements in disease modeling in silico, in vitro and in vivo; ii) acquisition of a wide range of biomedical information combined with the development of computational toolsets for flexible and integrative analyses of multi-assay datasets. Our deeper understanding of oncogenic mechanisms has finally begun to have a crucial impact on clinical decisions at several steps, from cancer prevention and diagnosis to therapeutic intervention. However, precision oncology still encounters several unresolved hurdles including tumour heterogeneity and recurrence as well as unexplained drug resistance and lack of effective ways to monitor response to therapeutic treatments. Notably, limitations in biomedical research regulation and governance represent additional debatable issues that need careful consideration.