Detection of Drugs and Their Metabolites in Oral Fluid Book

Detection of Drugs and Their Metabolites in Oral Fluid


  • Author : Robert M. White
  • Publisher : Elsevier
  • Release Date : 2018-02-23
  • Genre: Science
  • Pages : 140
  • ISBN 10 : 9780128145968

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Detection of Drugs and Their Metabolites in Oral Fluid Excerpt :

Detection of Drugs and Their Metabolites in Oral Fluid presents the analytical chemistry methods used for the detection and quantification of drugs and their metabolites in human oral fluid. The authors summarize the state of the science, including its strengths, weaknesses, unmet methodological needs, and cutting-edge trends. This volume covers the salient aspects of oral fluid drug testing, including specimen collection and handling, initial testing, point of collection testing (POCT), specimen validity testing (SVT), and confirmatory and proficiency testing. Analytes discussed include amphetamines, cannabinoids, cocaine, opiates, phencyclidine, cannabimimetics, and miscellaneous drugs. This practical guide helps users turn knowledge into practice, moving logically from an outline of the problem, to the evaluation of the appropriateness of oral fluid as a test medium, and finally to a consideration of detection methods and their validation and employment. Compares different collection and testing systems to assist readers involved in clinical or forensic practice in selecting oral fluid as the matrix of choice Provides a sound basis for the detection of drugs and their metabolites in oral fluid and the interpretation of both positive and negative Places the need, or lack thereof, for specimen validity testing and confirmation testing in context with the purposes of oral fluid testing Describes drugs and drug classes that can be tested, along with useful information on a patient/donor’s drug status

Drugs of Abuse Book

Drugs of Abuse


  • Author : Raphael C. Wong
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-05
  • Genre: Medical
  • Pages : 308
  • ISBN 10 : 9781592599516

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Drugs of Abuse Excerpt :

A comprehensive review of the science of drug testing in all its aspects, placing emphasis on technologies that use body fluids other than urine for determining the presence of drugs of abuse. The authors discuss the various body fluid specimens suitable for testing for illicit drugs-particularly saliva, sweat, and hair-describe the structural and manufacturing aspects of on-site testing devices based on lateral flow immunoassay, and detail the pitfalls of using these specimens. They also discuss in detail the problem of sample adulteration and its detection. Since oral fluid has the best potential of succeeding urine as the next matrix of choice for drug detection, four popular saliva testing devices are examined: Intercept®, the Drager Drug Test®, Oratect®, and Drugwipe. Political, social, and legal issues are also considered in articles on privacy, the use of drug testing in courts, and the problem of sample adulteration.

Workplace Drug Testing Book

Workplace Drug Testing


  • Author : Alain Verstraete
  • Publisher : Pharmaceutical Press
  • Release Date : 2011
  • Genre: Medical
  • Pages : 461
  • ISBN 10 : 9780853696940

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Workplace Drug Testing Excerpt :

This comprehensive text provides clear explanations of the effects of drugs on human performance and the need for workplace drug testing. It provides essential information on the regulatory and legal frameworks around the world, how to set policies and coverage of all aspects of drug analysis and the associated interpretation of results. Contents include: * Epidemiology of drug use in the working population * The evidence base and guidelines for workplace drug testing * Legal, regulatory aspects and policies for drugs and alcohol * Urine and alternative sample collection process * Analytical techniques and specimen adulteration. * Case studies of successful programmes are also included to illustrate the principles discussed. Written by internationally acknowledged experts this informative book will be essential reading for anyone interested in workplace drug testing or setting up such a system including clinical and forensic toxicologists, occupational health physicians, nurses, human resources, drug counselling and treatment providers, analytical chemists and lawyers.

Critical Issues in Alcohol and Drugs of Abuse Testing Book

Critical Issues in Alcohol and Drugs of Abuse Testing


  • Author : Amitava Dasgupta
  • Publisher : Academic Press
  • Release Date : 2019-01-10
  • Genre: Science
  • Pages : 560
  • ISBN 10 : 9780128156087

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Critical Issues in Alcohol and Drugs of Abuse Testing Excerpt :

Critical Issues in Alcohol and Drugs of Abuse Testing, Second Edition, addresses the general principles and technological advances for measuring drugs and alcohol, along with the pitfalls of drugs of abuse testing. Many designer drugs, for example, are not routinely tested in drugs of abuse panels and may go undetected in a drug test. This updated edition is a must-have for clinical pathologists, toxicologists, clinicians, and medical review officers and regulators, bridging the gap between technical and clinical information. Topics of note include the monitoring of pain management drugs, bath salts, spices (synthetic marijuana), designer drugs and date rape drugs, and more. Serves as a ready resource of information for alcohol and drug testing Ideal resource for making decisions related to the monitoring and interpretation of results Includes concise content for clinical laboratory scientists, toxicologists and clinicians

Principles of Forensic Toxicology Book

Principles of Forensic Toxicology


  • Author : Barry S. Levine
  • Publisher : Springer Nature
  • Release Date : 2020-08-13
  • Genre: Medical
  • Pages : 691
  • ISBN 10 : 9783030429171

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Principles of Forensic Toxicology Excerpt :

The fifth edition of the best-selling Principles in Forensic Toxicology continues in the tradition of excellence in academic publishing. With over 10 years of classroom-tested and continually updated content, the new edition contains significant updates and 7 new chapters on new topics including drug-facilitated crimes, derivatization, quantitation, measurement uncertainty/traceability, statistics, oral fluid testing, and drugs in embalmed specimens. Part One covers the major sub-disciplines of forensic toxicology in addition to pharmacological concepts. Part Two addresses specimen preparation, laboratory testing and instrumental analysis, while Part Three discusses common analytes including cocaine, opioids, alcohol, and marijuana. Adopted for courses in many of the top universities for forensic science and used by respected medical examiner’s offices and crime laboratories worldwide, Principles of Forensic Toxicology prepares the next generation of forensic toxicologists and continues to be an important reference in professional practice.

The ASAM Essentials of Addiction Medicine Book

The ASAM Essentials of Addiction Medicine


  • Author : Abigail Herron
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2019-02-01
  • Genre: Medical
  • Pages : 736
  • ISBN 10 : 9781975107963

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The ASAM Essentials of Addiction Medicine Excerpt :

Derived from ASAM’s definitive work,Principles of Addiction Medicine, 6th Edition, this companion resource is ideal for residents, fellows, and practitioners in psychiatry, as well as addiction medicine specialists and other healthcare workers who provide care to patients with substance use disorders. Streamlined and easy to use, the Essentials volume provides authoritative information on everything from the pharmacology of addiction through diagnosis, assessment, and early intervention—all in concise, easy-to-navigate format for ease of reference.

Forensic Toxicology Book

Forensic Toxicology


  • Author : Susannah Davies
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-03-15
  • Genre: Medical
  • Pages : 569
  • ISBN 10 : 9781788018104

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Forensic Toxicology Excerpt :

New designer drugs, access to databases, and changing availability of samples for analysis have changed the face of modern forensic toxicology in recent years. Forensic Toxicology: Drug Use and Misuse brings together the latest information direct from experts in each sub-field of the discipline providing a broad overview of current thinking and the most innovative approaches to case studies. The text begins with an in-depth discussion of pharmaco­epidemiology, including information on the value of nationwide databases in forensic toxicology. The use and abuse of drugs in driving, sport and the workplace are then discussed by industry experts who are conducting case work in their field. Not only are new drug groups discussed (NPS), but also their constantly changing impact on drug legislation. Synthetic cannabinoids, khat and mephodrone are discussed in detail. Following a section devoted to legislation and defence, readers will find comprehensive chapters covering sample choice reflecting the increasing use of hair and oral fluid, and also the less commonly used sweat and nail analysis. New and old case examples are compared and contrasted in the final part of the book, which will enable readers to understand how drugs impact on each other and how the interpretative outcome of a case are dependent on many aspects. From use of pharmaceutical drugs in a clinical setting, through smart drugs to new psychoactive drugs, this book documents the wide range in which drugs today are abused. This book will be an essential resource for postgraduate students in forensic toxicology, and for researchers in forensic toxicology laboratories who need the latest data and knowledge.

Liquid Chromatography Book

Liquid Chromatography


  • Author : C. Kostakis
  • Publisher : Elsevier Inc. Chapters
  • Release Date : 2013-01-08
  • Genre: Science
  • Pages : 688
  • ISBN 10 : 9780128071151

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Liquid Chromatography Excerpt :

Practitioners of forensic toxicology are expected to detect, confirm, and quantify a chemically diverse range of drugs and poisons covering a number of orders of magnitude in concentration in challenging biological matrices. Developments in LC–MS have enabled a wider range of compounds to be analyzed using fewer extraction processes, practically eliminating the requirement for derivatization steps and with fewer instrumental analysis stages. This chapter provides the reader with a broad overview of the current capabilities offered by LC in this branch of analytical chemistry—as well as its limitations.

On Site Drug Testing Book

On Site Drug Testing


  • Author : Amanda J. Jenkins
  • Publisher : Springer Science & Business Media
  • Release Date : 2002-01-28
  • Genre: Medical
  • Pages : 270
  • ISBN 10 : 9781592592722

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On Site Drug Testing Excerpt :

It is at least a decade since scientists turned their imaginations to creating new compact, portable test instruments and self-contained test kits that could be used to analyze urine and saliva for alcohol, drugs, and their metabolites. Although the potential applications for such tests at the site of specimen collection, now called “on-site” or “point-of-care” testing, range far beyond hospital emergency rooms and law enforcement needs, it was catalyzed by the requirements of workplace drug testing and other drugs-of-abuse testing programs. These programs are now a minor national industry in the United States and in some western European countries, and cover populations as diverse as the military, incarcerated criminals, people suspected of driving under the influence of alcohol and other drugs, all athletes from college to professional ranks, and of course the general employed population, which is monitored for illegal drug use and numbers in the millions. It is not surprising, then, that the need for rapid and precise tests, conducted economically by trained professionals, has become a major goal. Current government approved and peer reviewed laboratory methods for urine analysis serve present needs very well and have become remarkably robust over the past twenty years, but the logistics of testing some moving populations, such as the military, the Coast Guard, workers on off-shore oil platforms, and athletes—perhaps the most mobile of these groups—are unacceptably cumbersome.

NFL Draft Book

NFL Draft


  • Author : Anonim
  • Publisher : PediaPress
  • Release Date : 2022-11-29
  • Genre: Uncategoriezed
  • Pages : 1713
  • ISBN 10 : 978186723xxxx

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NFL Draft Excerpt :

Detection of Drug Misuse Book

Detection of Drug Misuse


  • Author : Kim Wolff
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-07-05
  • Genre: Medical
  • Pages : 396
  • ISBN 10 : 9781788012317

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Detection of Drug Misuse Excerpt :

Drug misuse and dependence is an ever evolving field of study, which has exploded over recent years owing to the advent of the internet. Due to the ever-growing number of young people using drugs recreationally and the privatisation of drug screening and detection services, there is the need to disseminate evidence-based information concerning the technology and methods available for studying this expanding field. Detection of Drug Misuse describes the current state-of-the-art techniques used for identifying and confirming drug misuse as well as recent advances in biomarkers, instrumentation and analysis methodology. The title discusses both recreational and designer drugs, including non-addictive and addictive drugs. This book is a useful and fascinating resource for healthcare professionals working in the field of drug misuse as well as academics and postgraduates researching within analytical, chromatography, medicinal and pharmaceutical chemistry; drug metabolism; addiction science; and forensic toxicology, science and medicine.

Analgesics   Advances in Research and Application  2012 Edition Book

Analgesics Advances in Research and Application 2012 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2012-12-26
  • Genre: Medical
  • Pages : 69
  • ISBN 10 : 9781481611046

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Analgesics Advances in Research and Application 2012 Edition Excerpt :

Analgesics—Advances in Research and Application: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Analgesics in a concise format. The editors have built Analgesics—Advances in Research and Application: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Analgesics in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Analgesics—Advances in Research and Application: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Cannabis Crashes  Myths and Truths Book

Cannabis Crashes Myths and Truths


  • Author : Scott Macdonald
  • Publisher : Lulu Press, Inc
  • Release Date : 2021-03-23
  • Genre: Science
  • Pages : null
  • ISBN 10 : 9781678046606

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Cannabis Crashes Myths and Truths Excerpt :

This book is intended for students, policy makers, lawyers and experts in the field of substance use and crashes. I describe in simple terms epidemiological issues important for understanding whether conclusions from studies are justifiable and discover numerous myths and truths about cannabis and driving.

Handbook of HPLC Book

Handbook of HPLC


  • Author : Danilo Corradini
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Genre: Science
  • Pages : 715
  • ISBN 10 : 9781420016949

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Handbook of HPLC Excerpt :

High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the

Forensic Toxicology Book

Forensic Toxicology


  • Author : Nicholas T. Lappas
  • Publisher : Academic Press
  • Release Date : 2021-10-22
  • Genre: Medical
  • Pages : 544
  • ISBN 10 : 9780128192870

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Forensic Toxicology Excerpt :

The second edition of Forensic Toxicology: Principles and Concepts takes the reader back to the origins of forensic toxicology providing an overview of the largely unchanging principles of the discipline. The text focuses on the major tenets in forensic toxicology, including an introduction to the discipline, principles of forensic toxicology including pharmacokinetics, pharmacodynamics, drug interactions and toxicogenomics, fundamentals of forensic toxicology analysis, types of interpretations based on analytical forensic toxicology results, and reporting from the laboratory to the courtroom. Also included in the second edition is a Unit focused on the forensic toxicology of individual drugs of abuse. Includes significant emphasis on the fundamental principles and concepts of forensic toxicology Provides students with an introduction to the core tenets of the discipline, focusing on the concepts, strategies, and methodologies utilized by professionals in the field Coauthored by a forensic toxicologist with over 40 years of experience as a professor who has taught graduate courses in forensic and analytical toxicology and who has served as a consultant and expert witness in civil and criminal cases