Advances in Diagnosis and Management of Ovarian Cancer Book

Advances in Diagnosis and Management of Ovarian Cancer


  • Author : Samir A. Farghaly
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-11-19
  • Genre: Medical
  • Pages : 270
  • ISBN 10 : 9781461482710

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Advances in Diagnosis and Management of Ovarian Cancer Excerpt :

Ovarian Cancer: Advances in Diagnosis and Management presents unique international perspectives on this devastating disease. While ovarian cancer has mainly been considered a disease of the Western hemisphere, this book moves beyond our conventional understanding and embraces knowledge from around the world. The focus is on recent advances in diagnosis, including genetic screening, and improvements and expanded choices in management, such as the optimization of chemotherapeutic agents, gene therapy, and the latest laparoscopic and robotic surgical techniques. Further chapters address psychosocial and quality-of-life issues. This book is an excellent resource on the international state-of-the-art in the diagnosis and management of ovarian cancer and is aimed at oncologists, gynecologists, and fellows.

Rare Hereditary Cancers Book

Rare Hereditary Cancers


  • Author : Gabriella Pichert
  • Publisher : Springer
  • Release Date : 2016-04-02
  • Genre: Medical
  • Pages : 267
  • ISBN 10 : 3319299964

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Rare Hereditary Cancers Excerpt :

This book approaches the differential diagnosis and management of rare, hereditary cancer syndromes from a practical angle, addressing the issues pertinent to each tumour type as encountered by health professionals in their day-to-day practice. This book enables readers to correctly identify patients with rare cancer syndromes who would benefit from genetic counselling and testing, and provides the necessary knowledge for appropriate patient management and advising at-risk family members. It begins by describing recent advances in genetic testing for cancer-predisposing genes. Leading experts from Europe and Australia then offer detailed, up-to-date guidance on the diagnosis and management of a wide range of hereditary cancers. The concluding chapter examines the wider issues that are raised by genetic testing for rare cancer syndromes for patients, families and health professionals. This book is an invaluable source of information for all specialists involved in the care of such patients and their families.

Diagnosis and Management of Hereditary Cancer Book

Diagnosis and Management of Hereditary Cancer


  • Author : John W. Henson
  • Publisher : Academic Press
  • Release Date : 2021-03-20
  • Genre: Medical
  • Pages : 384
  • ISBN 10 : 9780323885829

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Diagnosis and Management of Hereditary Cancer Excerpt :

Many hereditary cancer syndromes are linked to alterations in single genes. Detection and clinical interpretation of these alterations can guide cancer risk reduction for patients and their families through screening, prophylactic measures, and other strategies. Diagnosis and Management of Hereditary Cancer summarizes hereditary syndromes and their associated cancers and genes. The information is presented in 50 practice-enhancing tables that relate clinical, genetic, diagnostic, and management aspects in a manner that has previously not been available in a single reference. Intended to guide the specialist as well the novice, this volume will elevate the care of hereditary cancer patients and their families. Unique table-based presentation of 50 key aspects of hereditary cancer Clinical features, genetics, genetic testing, diagnosis, counseling, and management of multiple hereditary cancer syndromes Table-based format to inter-relate clinical and scientific information Landscape layout for easier viewing of tabular information

Pediatric Cancer Genetics Book

Pediatric Cancer Genetics


  • Author : Nathaniel H. Robin
  • Publisher : Elsevier Health Sciences
  • Release Date : 2017-08-22
  • Genre: Medical
  • Pages : 350
  • ISBN 10 : 9780323495967

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Pediatric Cancer Genetics Excerpt :

Get a quick, expert overview of the many key facets of pediatric cancer genetics with this concise, practical resource by Dr. Nathaniel H. Robin and Meagan Farmer, MS, CGC, MBA. Ideal for pediatric oncologists and all providers who care for children, this easy-to-read reference addresses the remarkable potential of genetic testing as well as the complexities of choosing the correct test, understanding the results, and counseling the family. Features a wealth of information on pediatric cancer genetics, including the epidemiology and biology of cancer and the genetic evaluation process and role of genetic counselors. Highlights examples of syndromes that present in childhood and increase susceptibility to cancer. Discusses the genetic evaluation process in context of the multidisciplinary care of children with cancer. Considers the ethical and legal issues of genetic testing in children and provides illustrative case examples. Consolidates today’s available information and guidance in this timely area into one convenient resource.

Diagnostic Pathology  Familial Cancer Syndromes E Book Book

Diagnostic Pathology Familial Cancer Syndromes E Book


  • Author : Vania Nosé
  • Publisher : Elsevier Health Sciences
  • Release Date : 2020-02-14
  • Genre: Medical
  • Pages : 896
  • ISBN 10 : 9780323712057

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Diagnostic Pathology Familial Cancer Syndromes E Book Excerpt :

This expert volume in the Diagnostic Pathology series is an excellent point-of-care resource for practitioners at all levels of experience and training. Physicians should have the knowledge derived from morphological findings to identify the likelihood of a cancer patient having an additional underlying familial syndrome— and to decide if that patient should undergo molecular genetic evaluation. This volume is specifically designed to help pathologists, oncologists, and other physicians who diagnose and treat cancer to recognize syndromes and syndrome- associated neoplasms and advise patients and their families on the possibility of a familial syndrome and their risk of developing other tumors. Diagnostic Pathology: Familial Cancer Syndromes, second edition, is an easy-to-use, one-stop reference for information on hereditary cancer syndromes, including differential diagnosis and management, that offers a templated, highly formatted design; concise, bulleted text; and superior color images throughout. Contains all the information necessary to determine whether a neoplasm typically encountered in daily practice is sporadic or related to a familial cancer syndrome Features a revised structure to keep you up to date: Part I includes more than 80 detailed chapters describing diagnoses associated with familial cancer syndromes; Part II contains more than 70 chapters with detailed descriptions of major syndromes (cross-referenced with diagnoses); and Part III features a molecular factors index that includes a complete description of each known gene associated with a familial cancer syndrome Contains updated chapters with newly classified GI, neurology, multiple organ, eye, endocrine, GYN, and kidney tumors, as well as more than 20 entirely new chapters covering recently recognized syndromes Incorporates up-to-date molecular findings and their significance for familial cancer syndromes; new techniques and technologies being used to discover gene mutations and other altera

The Breast Cancer Book Book

The Breast Cancer Book


  • Author : Kenneth D. Miller
  • Publisher : JHU Press
  • Release Date : 2021-09-28
  • Genre: Health & Fitness
  • Pages : 457
  • ISBN 10 : 9781421441900

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The Breast Cancer Book Excerpt :

"Providing comprehensive, current, and reliable information on breast cancer, this book, written by an experienced oncologist, a surgeon, and a breast cancer survivor, informs and inspires readers, wherever they are in the breast cancer experience. Patient stories, essays from medical specialists, and illustrations add clarity and insight"--

Diagnosis and Management of Ovarian Disorders Book

Diagnosis and Management of Ovarian Disorders


  • Author : Albert Altchek
  • Publisher : Elsevier
  • Release Date : 2003-09-04
  • Genre: Medical
  • Pages : 568
  • ISBN 10 : 9780080494517

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Diagnosis and Management of Ovarian Disorders Excerpt :

This updated second edition of Diagnosis and Management of Ovarian Disorders provides thorough, yet succinct insight into the ever-changing realm of ovarian disorders. It presents a novel multidisciplinary approach to the subject as described by clinicians, surgeons, pathologists, basic scientists and related medical researchers. Topics covered include reproductive technology, early diagnosis of ovarian cancer, and management of menopause among others. The breadth of information provided by this book will appeal to clinicians and researchers involved in the study and treatment of ovarian disorders. KEY FEATURES * Includes updated information on early diagnosis of ovarian cancer * Reviews new diagnostic techniques for ovarian disorders * Discusses latest information on reproductive technology * Presents translational treatment linking laboratory research with clinical medicine

Principles of Clinical Cancer Genetics Book

Principles of Clinical Cancer Genetics


  • Author : Daniel C. Chung
  • Publisher : Springer Science & Business Media
  • Release Date : 2010-07-20
  • Genre: Medical
  • Pages : 227
  • ISBN 10 : 9780387938462

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Principles of Clinical Cancer Genetics Excerpt :

Advances in genetics are transforming estimates of an individual’s risk of developing cancer and approaches to prevention and management of cancer in those who may have increased susceptibility. Identifying and caring for patients with hereditary cancer syndromes and their family members present a complex clinical, scientific and social challenge. This textbook, by leading experts at Massachusetts General Hospital Cancer Center, highlights the current understanding of the genetics of hereditary cancers of the breast, ovary, colorectum, stomach, pancreas, kidney, skin, and endocrine organs. Practical guidelines for the use of genetic testing, cancer screening and surveillance, prophylactic surgery, and promising targeted therapeutic agents are discussed. In addition, ongoing research involving genome-wide screens to identify novel modest risk-associated genetic loci are explored, along with new approaches to the application of genetic markers in guiding therapeutic options.

Lynch Syndrome  Hnpcc  and Microsatellite Instability Book

Lynch Syndrome Hnpcc and Microsatellite Instability


  • Author : A. Umar
  • Publisher : Ios PressInc
  • Release Date : 2004-01-01
  • Genre: Medical
  • Pages : 110
  • ISBN 10 : 158603491X

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Lynch Syndrome Hnpcc and Microsatellite Instability Excerpt :

Since experimental studies with microsatellite instability (MSI)-positive and -negative cell lines as well as clinical data suggest different responses to chemotherapeutic agents, the assessment of MSI status of the tumors is important. It also serves as a screening method for tumors of the hereditary non-polyposis colorectal cancer (HNPCC) spectrum. In cases of sporadic colorectal cancer there is a growing body of evidence indicating the improved prognosis associated with this group of tumors. Furthermore, failure to recognise familial cancer will have a negative impact on the patient's and family's management. Melecular testing for MSI is relatively expensive, however, a combination with immunohisto-chemical (IHC) detection of mismatch repair defects provides some relief to the cost as IHC is relatively inexpensive, fast and technically simple. This book edition of Disease Markers is focused on both the disease manifestations as well as the recent revised Bethesda Guidelines (18, 19) for the diagnosis and decision for genetic testing that will eventually lead to better understanding of the Lynch syndrome (HNPCC) and the MSI phenotype.

Hereditary Breast Cancer Book

Hereditary Breast Cancer


  • Author : Claudine Isaacs
  • Publisher : CRC Press
  • Release Date : 2007-09-19
  • Genre: Medical
  • Pages : 400
  • ISBN 10 : 9781420020366

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Hereditary Breast Cancer Excerpt :

Intended for medical oncologists, surgeons, obstetricians, gynecologists, geneticists, genetic counselors, and primary care physicians, this text presents the epidemiological, biological, and clinical issues associated with hereditary breast cancer. It offers clear guidance on the application and utilization of cancer risk assessment models, geneti

Management of Endometrial Cancer Book

Management of Endometrial Cancer


  • Author : Mansoor R. Mirza
  • Publisher : Springer
  • Release Date : 2019-08-26
  • Genre: Medical
  • Pages : 324
  • ISBN 10 : 9783319645131

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Management of Endometrial Cancer Excerpt :

This practical reference book provides up-to-date, evidence-based multidisciplinary guidelines on the epidemiology, biology, diagnosis, and treatment of endometrial cancer. Individual chapters focus on topics such as hormonal interactions, cancer prevention, genetic classification and its clinical applications. Recent advances in diagnostic methods are described. The treatment-oriented chapters include coverage of the roles of lymphadenectomy and sentinel node dissection, surgical complications, radiation techniques, and chemotherapy in early-stage disease. Treatment options in advanced disease, including hormonal therapy and targeted therapy, are considered separately, as is the management of rare tumor types. The authors are international key opinion leaders. Summaries of the ESMO/ESGO/ESTRO guidelines on management are included. Each clinical chapter ends with a summary of recommendations with the level of evidence.

Familial Cancer Book

Familial Cancer


  • Author : Hansjakob Müller
  • Publisher : S Karger Ag
  • Release Date : 1985
  • Genre: Medical
  • Pages : 320
  • ISBN 10 : UOM:39015010670019

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Familial Cancer Excerpt :

Hereditary Colorectal Cancer Book

Hereditary Colorectal Cancer


  • Author : Laura Valle
  • Publisher : Springer
  • Release Date : 2018-05-04
  • Genre: Medical
  • Pages : 505
  • ISBN 10 : 9783319742595

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Hereditary Colorectal Cancer Excerpt :

This book provides information on a wide variety of issues ranging from genetics to clinical description of the syndromes, genetic testing and counseling, and clinical management including surveillance, surgical and prophylactic interventions, and chemoprevention. Moreover, current hot issues, such as the identification of novel causal genes and the challenges we face, and the relevance of cancer risk modifiers, both genetic and environmental, are also discussed. This reference book is great for geneticists, oncologists, genetic counselors, researchers, clinicians, surgeons and nurses dedicated to, or interested in, hereditary cancer. The best and most recognized experts in the field have contributed to this project, guaranteeing updated information, accuracy and the discussion of topical issues.

Prophylactic Surgery Book

Prophylactic Surgery


  • Author : Osman Nuri Dilek
  • Publisher : Springer Nature
  • Release Date : 2021-04-16
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 9783030668532

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Prophylactic Surgery Excerpt :

This volume introduces the reader to the most important standards and principles of prophylactic surgery. After discussing the comparative effectiveness of screening in the treatment of hereditary cancer syndromes and evaluating genetic predisposition, the book moves on to address ethical, legal, social and cost-effectiveness dimensions of prophylactic surgery. With the aim of preventing hereditary predisposition syndromes, it also includes a chapter on the application of preventive surgery to all specific fields of surgery. Given its scope, the book will appeal to a broad readership, from experienced surgeons to students.