Early Vascular Aging  EVA  Book

Early Vascular Aging EVA

  • Author : Peter M Nilsson
  • Publisher : Academic Press
  • Release Date : 2015-08-06
  • Genre: Medical
  • Pages : 376
  • ISBN 10 : 9780128016763

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Early Vascular Aging (EVA): New Directions in Cardiovascular Protection brings together the last decade of research related to the characterization of EVA, as well as the predictive power of pulse wave velocity (PWV). The book presents a novel approach to the problem of cardiovascular disease, showing it in relation to great vessels disease and revealing a comprehensive approach to the problem of increased rigidity of the great vessels, its causes, and further consequences. Information provided is accompanied by online access to a supplemental website with video clips of anatomic specimens, cardiac imaging, and surgical procedures. Introduces the latest information on early vascular aging (EVA), complete with summaries of recent evidence and guidelines for relevant risk factor control Ideal reference for the study of vascular aging, pulse wave velocity, arteriosclerosis, EVA, arterial stiffness, vascular, PWV biomarkers, and cardiovascular disease Contains all the relevant information available from different fields of knowledge (from basic biology to epidemiology) in regard to EVA Provides evidence that leads to a new target for interventions, early vascular aging (EVA) in subjects with early onset increased arterial stiffness Includes online access to a supplemental website with video clips of anatomic specimens, cardiac imaging, and surgical procedures

Cardiovascular Disease in the Elderly Book

Cardiovascular Disease in the Elderly

  • Author : Gary Gerstenblith
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-03
  • Genre: Medical
  • Pages : 418
  • ISBN 10 : 9781592599417

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A panel of clinicians, researchers, and leaders in the field review and discuss the latest findings on the pathophysiology, diagnosis, and management of cardiovascular disease in the older patient. The authors explain the physiological changes associated with the normal aging process that may lead to the development of disease, to adverse consequences once disease develops, and which alter the risk-benefit equation for medical and other interventions designed to diagnose, assess, and treat cardiovascular disease. The focus is on particularly common syndromes in the elderly, including cardiac failure with normal ejection fraction, isolated systolic hypertension, and atrial fibrillation. Wherever possible, the authors take an evidence-based approach to recommendations and rely heavily on prospective clinical trials.

Textbook of Vascular Medicine Book

Textbook of Vascular Medicine

  • Author : Rhian M. Touyz
  • Publisher : Springer
  • Release Date : 2019-08-02
  • Genre: Medical
  • Pages : 503
  • ISBN 10 : 9783030164812

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This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

The Cambridge Handbook of Successful Aging Book

The Cambridge Handbook of Successful Aging

  • Author : Rocío Fernández-Ballesteros
  • Publisher : Cambridge University Press
  • Release Date : 2019-01-24
  • Genre: Psychology
  • Pages : null
  • ISBN 10 : 9781108641432

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Recent studies show that more people than ever before are reaching old age in better health and enjoying that health for a longer time. This Handbook outlines the latest discoveries in the study of aging from bio-medicine, psychology, and socio-demography. It treats the study of aging as a multidisciplinary scientific subject, since it requires the interplay of broad disciplines, while offering high motivation, positive attitudes, and behaviors for aging well, and lifestyle changes that will help people to stay healthier across life span and in old age. Written by leading scholars from various academic disciplines, the chapters delve into the most topical aspects of aging today - including biological mechanisms of aging, aging with health, active and productive aging, aging with satisfaction, aging with respect, and aging with dignity. Aimed at health professionals as well as general readers, this Cambridge Handbook offers a new, positive approach to later life.

Effects of Aerobic Exercise on Mental Stress induced Arterial Stiffness in Black Young Adults Book

Effects of Aerobic Exercise on Mental Stress induced Arterial Stiffness in Black Young Adults

  • Author : Lakeisha H. Johnson
  • Publisher : Unknown
  • Release Date : 2022
  • Genre: Aerobic exercises
  • Pages : 0
  • ISBN 10 : OCLC:1376022756

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Black populations account for the highest rates of cardiovascular disease (CVD) mortality, morbidity, and subclinical indices of CVD. Studies support that there are ethnic disparities in arterial stiffness, particularly manifested as early vascular aging. While ethnic disparities cannot be solely explained by traditional CVD risk factors, psychosocial factors, such as mental stress, have correlated to increased arterial stiffness. Exercise has been mentioned as a notable therapeutic mechanism for stressrelated stiffness. Thus, the purpose of this study was to determine the effects of an acute bout of moderate-intensity aerobic exercise on mental stress-induced arterial stiffness in Black young adults. METHODS: 10 apparently healthy individuals (4 male, 6 female, 22.0 ± 1.8 years and BMI 25.3 ± 3.6 kg/m2) performed 30 minutes of treadmill exercise at 64-76% of heart rate maximum before a 5-minute mental stress task. Arterial stiffness (measured as carotid femoral pulse wave velocity [cfPWV]) and brachial and central hemodynamic measures (bSBP, bDBP, bPP, cSBP, cDBP, cPP, MAP, HR, AP, AIx, AIx@75) were recorded before and after the task and compared to results gathered on the control day (consisting of the same mental stress task without prior exercise). Participants were randomly assigned to either the control or exercise trial first. RESULTS: The mental stress task increased PWV, independent of exercise (main effect for time, p 0.001). The absolute change in PWV from pre to post 0 minutes was similar (p 0.05) for control (+0.43±0.39) and exercise (+0.33±0.70) trials. Mental stress had a main effect for time (p

Vascular Aging  Facts and Factors Book

Vascular Aging Facts and Factors

  • Author : Elisabet Vila
  • Publisher : Frontiers E-books
  • Release Date : 2023-06-03
  • Genre: Uncategoriezed
  • Pages : 97
  • ISBN 10 : 9782889190522

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The increasing mean age of the population in developed countries has turned out to be an economic and social problem. Cardiovascular disease has long been considered to be age related in terms of their onset and progression. As such, we can say that the increase in life expectancy goes in parallel with increased incidence of cardiovascular disease. With age, a number of changes occur in the vasculature altering the homeostasis of the irrigated organs promoting target organ damage. While different adaptive mechanisms to protect vessels against mild stress have been described, the aging process induces a progressive failure of protective mechanisms, leading to vascular changes and higher susceptibility to cardiovascular diseases. Indeed, vascular aging is exacerbated by coexisting cardiovascular risk factors, such as hypertension, metabolic syndrome and diabetes. Compelling evidence indicates that diminished endothelial relaxation and increase, decrease, or no change in contractile responses to several agonists is associated with aging. There is an increase of vasoconstrictor factors expression and a decrease of vasodilators. Morphologic changes include lumen diameter enlargement, wall thickening and alterations of matrix substances as increased collagen or decreased elastin deposition, ultimately leading to greater arterial stiffening (reduced compliance). Importantly, arterial stiffness is an independent predictor of cardiovascular morbidity and mortality. Cellular and molecular mechanisms have also been documented. Senescence at the cellular level involves alterations in Ca2+ signaling and down regulation of anti-aging proteins. Both endothelial and smooth muscle cells change their number, morphology, function and their regenerative ability. Aging is also associated with a gradual loss of antioxidant defense mechanisms, a proinflammatory shift in the cytokine expression profile and a production of reactive oxygen species such as superoxide (O2-) that promotes the b

A Life Course Approach to Healthy Ageing Book

A Life Course Approach to Healthy Ageing

  • Author : Diana Kuh
  • Publisher : Oxford University Press
  • Release Date : 2014
  • Genre: Family & Relationships
  • Pages : 299
  • ISBN 10 : 9780199656516

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This title investigates the lifetime determinants of healthy ageing and their implications for policy and practice, bringing together authorities in ageing research and knowledge transfer from across the world.

Sex Specific Analysis of Cardiovascular Function Book

Sex Specific Analysis of Cardiovascular Function

  • Author : Peter L. M. Kerkhof
  • Publisher : Springer
  • Release Date : 2018-07-26
  • Genre: Medical
  • Pages : 725
  • ISBN 10 : 9783319779324

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This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data. This innovative title is the first to offer the elements necessary to consider sex-related properties in both clinical and basic studies regarding the heart and circulation on multiscale levels (i.e. molecular, cellular, electrophysiologically, neuroendocrine, immunoregulatory, organ, allometric, and modeling). Observed differences at (ultra)cellular and organ level are quantified, with focus on clinical relevance and implications for diagnosis and patient management. Since the cardiovascular system is of vital importance for all tissues, Sex-Specific Analysis of Cardiovascular Function is an essential source of information for clinicians, biologists, and biomedical investigators. The wide spectrum of differences described in this book will also act as an eye-opener and serve as a handbook for students, teachers, scientists and practitioners.

Integrative Cardiology Book

Integrative Cardiology

  • Author : Massimo Fioranelli
  • Publisher : Springer
  • Release Date : 2017-02-10
  • Genre: Medical
  • Pages : 276
  • ISBN 10 : 9783319400105

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This book is a detailed guide to a new integrative approach to the prevention and treatment of various cardiac disorders and risk factors, including coronary artery disease, congestive heart failure, arrhythmias, dyslipidemia, and hypertension. This approach combines various strategies, including metabolic cardiology, low-dose medicine, exercise programs, stress management programs, evaluation for inherited risk factors, and various other healing modalities. Metabolic cardiology focuses on the prevention, management, and treatment of cardiovascular disease at the cellular level through biochemical interventions with nutritional supplements that can promote energy production in the heart. Low-dose medicine, on the other hand, interprets pathological phenomena as an imbalance in intercellular signaling that may be corrected through the administration of low physiological doses of messenger molecules. Therapies outside of mainstream medicine may also be deployed in integrative cardiology, for example acupuncture, herbal medicine, and homeopathy. Integrative Cardiology will be of interest to all practitioners wishing to learn about an approach that incorporates the incredible advances in medication and technology with a focus on nutrition, lifestyle, and mind–body influences.

Promoting Cardiovascular Health in the Developing World Book

Promoting Cardiovascular Health in the Developing World

  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2010-06-29
  • Genre: Medical
  • Pages : 482
  • ISBN 10 : 0309157617

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Cardiovascular disease (CVD), once thought to be confined primarily to industrialized nations, has emerged as a major health threat in developing countries. Cardiovascular disease now accounts for nearly 30 percent of deaths in low and middle income countries each year, and is accompanied by significant economic repercussions. Yet most governments, global health institutions, and development agencies have largely overlooked CVD as they have invested in health in developing countries. Recognizing the gap between the compelling evidence of the global CVD burden and the investment needed to prevent and control CVD, the National Heart, Lung, and Blood Institute (NHLBI) turned to the IOM for advice on how to catalyze change. In this report, the IOM recommends that the NHLBI, development agencies, nongovernmental organizations, and governments work toward two essential goals: creating environments that promote heart healthy lifestyle choices and help reduce the risk of chronic diseases, and building public health infrastructure and health systems with the capacity to implement programs that will effectively detect and reduce risk and manage CVD. To meet these goals, the IOM recommends several steps, including improving cooperation and collaboration; implementing effective and feasible strategies; and informing efforts through research and health surveillance. Without better efforts to promote cardiovascular health, global health as a whole will be undermined.

How Tobacco Smoke Causes Disease Book

How Tobacco Smoke Causes Disease

  • Author : Anonim
  • Publisher : Health and Human Services Department
  • Release Date : 2010
  • Genre: Government publications
  • Pages : 728
  • ISBN 10 : UCSD:31822037817723

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.

Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease Book

Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease

  • Author : Julio A. Chirinos
  • Publisher : Academic Press
  • Release Date : 2022-03-28
  • Genre: Science
  • Pages : 1032
  • ISBN 10 : 9780323916486

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Textbook of Arterial Stiffness and Pulsatile Hemodynamics in Health and Disease, Two Volume Set covers the principles, physiology, biologic pathways, clinical implications and therapeutics surrounding arterial stiffness and pulsatile hemodynamics, along with a thorough overview of the field. The book presents complex engineering concepts in a way that those in science and medicine can more easily understand. It includes detailed illustrations, animations and slideshows. Additionally, it presents advanced bioengineering concepts in boxes for readers who wants more in-depth biophysical knowledge. This is a must-have reference for students, researchers and clinicians interested in learning more about this field. Incorporates case studies and calculations/worked examples with mathematical principles explained in a conceptual manner without complicated formulas Features chapter contributions from leading international researchers and clinicians Covers principles, physiology, biologic pathways, clinical implications and therapeutics

Brain Aging Book

Brain Aging

  • Author : David R. Riddle
  • Publisher : CRC Press
  • Release Date : 2007-04-19
  • Genre: Medical
  • Pages : 408
  • ISBN 10 : 1420005529

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Recognition that aging is not the accumulation of disease, but rather comprises fundamental biological processes that are amenable to experimental study, is the basis for the recent growth of experimental biogerontology. As increasingly sophisticated studies provide greater understanding of what occurs in the aging brain and how these changes occur

Senescence and Senescence Related Disorders Book

Senescence and Senescence Related Disorders

  • Author : Wang Zhiwei
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-02-20
  • Genre: Medical
  • Pages : 162
  • ISBN 10 : 9789535109976

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Senescence is a biological process that causes a progressive deterioration of structure and function of all organs chronologically. Recent studies have revealed the detailed molecular mechanisms of senescence using cell culture system and experimental organisms. It is thought that senescence is a potential cause for the development of various age-related disorders such as cancer, cardiovascular and neurodegenerative disorders. This book discusses in detail senescence and its related diseases by distinguished researchers and practicing clinicians. The cumulative knowledge from the studies could lead to developing new approaches for anti-senescence interventions.