Epilepsy Book


  • Author : Gregory D. Cascino
  • Publisher : John Wiley & Sons
  • Release Date : 2021-02-22
  • Genre: Medical
  • Pages : 544
  • ISBN 10 : 9781119432005

Epilepsy Excerpt :

Designed to provide a comprehensive but accessible introduction to epilepsy and seizure disorders, Epilepsy, 2nd edition provides state-of-the-art information in a concise format useful to a wide audience, from neurology residents to epilepsy fellows and practitioners. This illustrated guide to the assessment, diagnosis, and treatment of epilepsy is a valuable resource enabling clinicians to stay on top of the latest recommendations for best practice.

Models of Seizures and Epilepsy Book

Models of Seizures and Epilepsy

  • Author : Asla Pitkänen
  • Publisher : Academic Press
  • Release Date : 2017-06-14
  • Genre: Science
  • Pages : 1178
  • ISBN 10 : 9780128040676

Models of Seizures and Epilepsy Excerpt :

Models of Seizures and Epilepsy, Second Edition, is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models to address key questions in the field. The book also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research as well as R&D drug development. Contents include the current spectrum of models available to model different epilepsy syndromes, epilepsy in transgenic animals, comorbidities in models of epilepsy, and novel technologies to study seizures and epilepsies in animals. Provides a comprehensive reference detailing animal models of epilepsy and seizure Offers insights on the use of novel technologies that can be applied in experimental epilepsy research Edited by leading experts in the field that provide not only technical reviews of these models but also conceptual critiques Comments on the strengths and limitations of various models, including their relationship to clinical phenomenology and their value in developing better understanding and treatments

Oxford Textbook of Epilepsy and Epileptic Seizures Book

Oxford Textbook of Epilepsy and Epileptic Seizures

  • Author : Samden Lhatoo
  • Publisher : Oxford University Press
  • Release Date : 2013
  • Genre: Medical
  • Pages : 395
  • ISBN 10 : 9780199659043

Oxford Textbook of Epilepsy and Epileptic Seizures Excerpt :

Part of the Oxford Textbooks in Clinical Neurology (OTCN) series, this volume covers the scientific basis, clinical diagnosis, and treatment of epilepsy and epileptic seizures, and is complemented by an online edition.

The Epilepsy Book  A Companion for Patients Book

The Epilepsy Book A Companion for Patients

  • Author : Thalia Valeta
  • Publisher : Springer
  • Release Date : 2017-11-24
  • Genre: Medical
  • Pages : 208
  • ISBN 10 : 9783319616797

The Epilepsy Book A Companion for Patients Excerpt :

This book presents scientific evidence about epilepsy along with straightforward guidance and recommendations. Responses to frequently asked questions and clarification of uncertainties are provided to empower patients to optimize their medical, psychological and social care. This book helps mediate between patients and health care professionals and can assist both sides to understand the condition of epilepsy at all levels. The information provided in the book empowers patients to share decision making with their carers and clinicians and enables them to make informed decisions, by taking into account the best scientific evidence, as well as the patients’ values and preferences. The Epilepsy Book: A Companion for Patients is ideal for patients with epilepsy and their carers, and will also be of interest to health care professionals, medical students and teachers. Thalia Valeta’s approach to epilepsy facilitates deeper understanding of the unmet needs and expectations of patients.

Astrocytes and Epilepsy Book

Astrocytes and Epilepsy

  • Author : Jacqueline A. Hubbard
  • Publisher : Academic Press
  • Release Date : 2016-07-05
  • Genre: Medical
  • Pages : 394
  • ISBN 10 : 9780128026243

Astrocytes and Epilepsy Excerpt :

Epilepsy is a devastating group of neurological disorders characterized by periodic and unpredictable seizure activity in the brain. There is a critical need for new drugs and approaches given than at least one-third of all epilepsy patients are not made free of seizures by existing medications and become "medically refractory". Much of epilepsy research has focused on neuronal therapeutic targets, but current antiepileptic drugs often cause severe cognitive, developmental, and behavioral side effects. Recent findings indicate a critical contribution of astrocytes, star-shaped glial cells in the brain, to neuronal and network excitability and seizure activity. Furthermore, many important cellular and molecular changes occur in astrocytes in epileptic tissue in both humans and animal models of epilepsy. The goal of Astrocytes and Epilepsy is to comprehensively review exciting findings linking changes in astrocytes to functional changes responsible for epilepsy for the first time in book format. These insights into astrocyte contribution to seizure susceptibility indicate that astrocytes may represent an important new therapeutic target in the control of epilepsy. Astrocytes and Epilepsy includes background explanatory text on astrocyte morphology and physiology, epilepsy models and syndromes, and evidence from both human tissue studies and animal models linking functional changes in astrocytes to epilepsy. Beautifully labelled diagrams are presented and relevant figures from the literature are reproduced to elucidate key findings and concepts in this rapidly emerging field. Astrocytes and Epilepsy is written for neuroscientists, epilepsy researchers, astrocyte investigators as well as neurologists and other specialists caring for patients with epilepsy. Presents the first comprehensive book to synthesize historical and recent research on astrocytes and epilepsy into one coherent volume Provides a great resource on the field of astrocyte biology and astrocyte-neuron i

Epilepsy Across the Spectrum Book

Epilepsy Across the Spectrum

  • Author : Institute of Medicine
  • Publisher : National Academies Press
  • Release Date : 2012-07-29
  • Genre: Medical
  • Pages : 568
  • ISBN 10 : 9780309259538

Epilepsy Across the Spectrum Excerpt :

Although epilepsy is one of the nation's most common neurological disorders, public understanding of it is limited. Many people do not know the causes of epilepsy or what they should do if they see someone having a seizure. Epilepsy is a complex spectrum of disorders that affects an estimated 2.2 million Americans in a variety of ways, and is characterized by unpredictable seizures that differ in type, cause, and severity. Yet living with epilepsy is about much more than just seizures; the disorder is often defined in practical terms, such as challenges in school, uncertainties about social situations and employment, limitations on driving, and questions about independent living. The Institute of Medicine was asked to examine the public health dimensions of the epilepsies, focusing on public health surveillance and data collection; population and public health research; health policy, health care, and human services; and education for people with the disorder and their families, health care providers, and the public. In Epilepsy Across the Spectrum, the IOM makes recommendations ranging from the expansion of collaborative epilepsy surveillance efforts, to the coordination of public awareness efforts, to the engagement of people with epilepsy and their families in education, dissemination, and advocacy for improved care and services. Taking action across multiple dimensions will improve the lives of people with epilepsy and their families. The realistic, feasible, and action-oriented recommendations in this report can help enable short- and long-term improvements for people with epilepsy. For all epilepsy organizations and advocates, local, state, and federal agencies, researchers, health care professionals, people with epilepsy, as well as the public, Epilepsy Across the Spectrum is an essential resource.

Diagnosis and Surgical Treatment of Epilepsy Book

Diagnosis and Surgical Treatment of Epilepsy

  • Author : Warren W. Boling
  • Publisher : MDPI
  • Release Date : 2019-01-09
  • Genre: Biology (General)
  • Pages : 136
  • ISBN 10 : 9783038974499

Diagnosis and Surgical Treatment of Epilepsy Excerpt :

This book is a printed edition of the Special Issue "Diagnosis and Surgical Treatment of Epilepsy" that was published in Brain Sciences

The Causes of Epilepsy Book

The Causes of Epilepsy

  • Author : Simon D. Shorvon
  • Publisher : Cambridge University Press
  • Release Date : 2011-04-14
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9781139495783

The Causes of Epilepsy Excerpt :

Causation is an aspect of epilepsy neglected in the scientific literature and in the conceptualization of epilepsy at a clinical and experimental level. It was to remedy this deficiency that this book was conceived. The book opens with a draft etiological classification that goes some way to filling the nosological void. The book is divided into four etiological categories: idiopathic, symptomatic, cryptogenic, and provoked epilepsies. Each chapter considers topics in a consistent fashion, dealing with the phenomenon of epilepsy in each etiology, including its epidemiology, clinical features and prognosis, and any specific aspects of treatment. The book is a comprehensive reference work, a catalogue of all important causes of epilepsy, and a clinical tool for all clinicians dealing with patients who have epilepsy. It is aimed at epileptologists and neurologists and provides a distillation of knowledge in a form that is helpful in the clinical setting.

Magnetic Resonance in Epilepsy Book

Magnetic Resonance in Epilepsy

  • Author : Ruben Kuzniecky
  • Publisher : Academic Press
  • Release Date : 2005-01-19
  • Genre: Medical
  • Pages : 464
  • ISBN 10 : 0080535712

Magnetic Resonance in Epilepsy Excerpt :

Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders. *Provides a crucial update of recent advances in imaging techniques *Timely publication as subject of neuroimaging is a very "hot" area in both clinical epilepsy and basic neuroscience research *Editors are well-respected in this field

Introduction to Epilepsy Book

Introduction to Epilepsy

  • Author : Gonzalo Alarcón
  • Publisher : Cambridge University Press
  • Release Date : 2012-04-26
  • Genre: Medical
  • Pages : 641
  • ISBN 10 : 9780521691581

Introduction to Epilepsy Excerpt :

Covers all aspects of epilepsy, from basic mechanisms to diagnosis and management, as well as legal and social considerations.

Epilepsy Book


  • Author : Jerome Engel
  • Publisher : Lippincott Williams & Wilkins
  • Release Date : 2008
  • Genre: Medical
  • Pages : 1272
  • ISBN 10 : 0781757770

Epilepsy Excerpt :

Written and edited by world-renowned authorities, this three-volume work is, to quote a reviewer, "the definitive textbook about seizures and epilepsy". This Second Edition is thoroughly updated and gives you a complete print and multimedia package: the three-volume set plus access to an integrated content Website. More than 300 chapters cover the spectrum of biology, physiology, and clinical information, from molecular biology to public health concerns in developing countries. Included are detailed discussions of seizure types and epilepsy syndromes; relationships between physiology and clinical events; psychiatric and medical comorbidity; conditions that could be mistaken for epilepsy; and an increasing range of pharmacologic, surgical, and alternative therapies, including vagus nerve stimulation and deep brain stimulation. This edition describes many new antiepileptic drugs, major advances in surgical treatment, and state-of-the-art neuroimaging, EEG, and other technologies for diagnosis and seizure prediction. A companion Website offers instant access to the complete, fully searchable text, plus an image bank of additional figures, video footage, and annual updates to selected chapters.

Seizures and Epilepsy Book

Seizures and Epilepsy

  • Author : Jerome Engel Jr
  • Publisher : Oxford University Press
  • Release Date : 2013-01-31
  • Genre: Medical
  • Pages : 737
  • ISBN 10 : 9780195328547

Seizures and Epilepsy Excerpt :

This second edition of 'Seizures and Epilepsy' is completely revised, due to tremendous advances in the understanding of the fundamental neuronal mechanisms underlying epileptic phenomena, as well as current diagnosis and treatment, which have been heavily influenced over the past several decades by seminal neuroscientific developments, particularly the introduction of molecular neurobiology, genetics, and modern neuroimaging. This resource covers a broad range of both basic and clinical epileptology.

Jasper s Basic Mechanisms of the Epilepsies Book

Jasper s Basic Mechanisms of the Epilepsies

  • Author : Jeffrey Noebels
  • Publisher : Oxford University Press
  • Release Date : 2012-06-01
  • Genre: Medical
  • Pages : 1264
  • ISBN 10 : 9780199842599

Jasper s Basic Mechanisms of the Epilepsies Excerpt :

H.H. Jasper, A.A. Ward, A. Pope and H.H. Merritt, chair of the Public Health Service Advisory Committee on the Epilepsies, National Institutes of Health, published the first volume on Basic Mechanisms of the Epilepsies (BME) in 1969. Their ultimate goal was to search for a "better understanding of the epilepsies and seek more rational methods of their prevention and treatment." Since then, basic and clinical researchers in epilepsy have gathered together every decade and a half with these goals in mind -- assessing where epilepsy research has been, what it has accomplished, and where it should go. In 1999, the third volume of BME was named in honor of H.H. Jasper. In line with the enormous expansion in the understanding of basic epilepsy mechanisms over the past four decades, this fourth edition of Jasper's BME is the most ambitious yet. In 90 chapters, the book considers the role of interactions between neurons, synapses, and glia in the initiation, spread and arrest of seizures. It examines mechanisms of excitability, synchronization, seizure susceptibility, and ultimately epileptogenesis. It provides a framework for expanding the epilepsy genome and understanding the complex heredity responsible for common epilepsies as it explores disease mechanisms of ion channelopathies and developmental epilepsy genes. It considers the mechanisms of conditions of epilepsy comorbidities. And, for the first time, this 4th edition describes the current efforts to translate the discoveries in epilepsy disease mechanisms into new therapeutic strategies. This book, considered the 'bible' of basic epilepsy research, is essential for the student, the clinician scientist and all research scientists who conduct laboratory-based experimental epilepsy research using cellular, brain slice and animal models, as well as for those interested in related disciplines of neuronal oscillations, network plasticity, and signaling in brain strucutres that include the cortex, hippocampus, and thalamu

Epilepsy Book


  • Author : David W. McCandless
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-11-02
  • Genre: Medical
  • Pages : 532
  • ISBN 10 : 1461403618

Epilepsy Excerpt :

The present volume is intended to be a synopsis of seizure disorders with a goal of describing key studies in animals and humans. The translation of pertinent findings from animal studies to human studies, and to potential human studies will be emphasized. Specific cogent animal studies/results which deserve exploration in human seizure disorders will be detailed. The current rate of translation is estimated to be from 7‐9 years, and the “success” rate of translation was very recently listed as less than one half. The success rate is defined as results in human studies which were predicted in advance by animal studies. Both the time between animal and human attempts plus the success rate need improvement.

Encyclopedia of Basic Epilepsy Research Book

Encyclopedia of Basic Epilepsy Research

  • Author : Anonim
  • Publisher : Academic Press
  • Release Date : 2009-05-27
  • Genre: Medical
  • Pages : 4224
  • ISBN 10 : 9780123739612

Encyclopedia of Basic Epilepsy Research Excerpt :

As a truly translational area of biomedical investigation, epilepsy research spans an extraordinary breadth of subjects and involves virtually every tool that modern neuroscience has at its disposal. The Encyclopedia of Basic Epilepsy Research provides an up to date, comprehensive reference for all epilepsy researchers. With an expert list of authors, the encyclopedia covers the full spectrum of research activities from genes and molecules to animal models and human patients. The encyclopedia's electronic format also provides unparalleled access to frequent updates and additions, while the limited edition print version provides another option for owning this content. The Encyclopedia of Basic Epilepsy Research is an essential resource for researchers of all levels and clinicians who study epilepsy. The only comprehensive reference for basic research and current activities in epilepsy Electronic format provides fast and easy access to updates and additions, with limited print version available as well Contains over 85 articles, all written by experts in epilepsy research