Essentials in Modern HPLC Separations Book

Essentials in Modern HPLC Separations


  • Author : Serban C. Moldoveanu
  • Publisher : Elsevier
  • Release Date : 2022-06-24
  • Genre: Science
  • Pages : 716
  • ISBN 10 : 9780323998369

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Essentials in Modern HPLC Separations Excerpt :

Essentials in Modern HPLC Separations, Second Edition discusses the role of separation in high performance liquid chromatography (HPLC). This new and updated edition systematically presents basic concepts as well as new developments in HPLC. Starting with a description of basic concepts, it provides important guidance for the practical utilization of various HPLC procedures, such as the selection of the HPLC type, proper choice of the chromatographic column, selection of mobile phase and selection of the method of detection, all of which are in correlation with the physico-chemical characteristics of the compounds separated. Every chapter has been carefully reviewed, with several new sections added to bring the book completely up-to-date. Hence, it is a valuable reference for students and professors in chemistry. Provides a thoroughly updated resource, with an entirely new section on Computer-aided Method Development in HPLC and new subsections on miniaturization and automation in HPLC, chemometric aspects of HPLC, green solvent use in HPLC, and more Includes insights into the chromatographic process to find the optimum solution for analyzing complex samples Presents a basis for understanding the utilization of modern HPLC for applications, particularly for the analysis of pharmaceutical, biological, food, beverage and environmental samples

Material Characterization Techniques and Applications Book

Material Characterization Techniques and Applications


  • Author : Euth Ortiz Ortega
  • Publisher : Springer Nature
  • Release Date : 2022
  • Genre: Detectors
  • Pages : 314
  • ISBN 10 : 9789811695698

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Material Characterization Techniques and Applications Excerpt :

This book presents commonly applied characterization techniques in material science, their brief history and origins, mechanism of operation, advantages and disadvantages, their biosensing applications, and troubleshooting for each technique, while addressing the challenges researchers face when working with these techniques. The book dedicates its focus to identifying physicochemical and electrochemical nature of materials including analyses of morphology, mass spectrometry, and topography, as well as the characterization of elemental, structural, thermal, wettability, electrochemical, and chromatography properties. Additionally, the main features and benefits of using coupled characterization techniques are discussed in this book.

Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry Book

Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry


  • Author : Carrillo-Cedillo, Eugenia Gabriela
  • Publisher : IGI Global
  • Release Date : 2022-03-18
  • Genre: Technology & Engineering
  • Pages : 298
  • ISBN 10 : 9781799896159

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Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry Excerpt :

Quality control in pharmaceutical products and medical devices is vital for users as failing to comply with national and international regulations can lead to accidents that could easily be avoided. For this reason, manufacturing a quality medical product will support patient safety. Microbiologists working in both the pharmaceutical and medical device industries face considerable challenges in keeping abreast of the myriad microbiological references available to them and the continuously evolving regulatory requirements. Quality Control Applications in the Pharmaceutical and Medical Device Manufacturing Industry presents the importance of quality control in pharmaceutical products and medical devices, which must have very high-quality standards to not cause problems to the health of patients. It reinforces and updates the knowledge of analytical, instrumental, and biological methods to demonstrate the correct quality control and good manufacturing practice for pharmaceutical products and medical devices. Covering topics such as pharmaceutical nano systems, machine learning, and software validation, this book is an essential resource for managers, engineers, supervisors, pharmacists, chemists, academicians, and researchers.

Introduction to Modern Liquid Chromatography Book

Introduction to Modern Liquid Chromatography


  • Author : Lloyd R. Snyder
  • Publisher : John Wiley & Sons
  • Release Date : 2011-09-20
  • Genre: Science
  • Pages : 960
  • ISBN 10 : 9781118210390

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Introduction to Modern Liquid Chromatography Excerpt :

The latest edition of the authoritative reference to HPLC High-performance liquid chromatography (HPLC) is today the leading technique for chemical analysis and related applications, with an ability to separate, analyze, and/or purify virtually any sample. Snyder and Kirkland's Introduction to Modern Liquid Chromatography has long represented the premier reference to HPLC. This Third Edition, with John Dolan as added coauthor, addresses important improvements in columns and equipment, as well as major advances in our understanding of HPLC separation, our ability to solve problems that were troublesome in the past, and the application of HPLC for new kinds of samples. This carefully considered Third Edition maintains the strengths of the previous edition while significantly modifying its organization in light of recent research and experience. The text begins by introducing the reader to HPLC, its use in relation to other modern separation techniques, and its history, then leads into such specific topics as: The basis of HPLC separation and the general effects of different experimental conditions Equipment and detection The column—the "heart" of the HPLC system Reversed-phase separation, normal-phase chromatography, gradient elution, two-dimensional separation, and other techniques Computer simulation, qualitative and quantitative analysis, and method validation and quality control The separation of large molecules, including both biological and synthetic polymers Chiral separations, preparative separations, and sample preparation Systematic development of HPLC separations—new to this edition Troubleshooting tricks, techniques, and case studies for both equipment and chromatograms Designed to fulfill the needs of the full range of HPLC users, from novices to experts, Introduction to Modern Liquid Chromatography, Third Edition offers the most up-to-date, comprehensive, and accessible survey of HPLC methods and applications available.

Modern HPLC for Practicing Scientists Book

Modern HPLC for Practicing Scientists


  • Author : Michael W. Dong
  • Publisher : John Wiley & Sons
  • Release Date : 2016-04-06
  • Genre: Science
  • Pages : 328
  • ISBN 10 : 9781119293606

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Modern HPLC for Practicing Scientists Excerpt :

A comprehesive yet concise guide to Modern HPLC Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include: HPLC operation Method development Maintenance and troubleshooting Modern trends in HPLC such as quick-turnaround and "greener" methods Regulatory aspects While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources. With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

HPLC for Pharmaceutical Scientists Book
Score: 4
From 4 Ratings

HPLC for Pharmaceutical Scientists


  • Author : Yuri V. Kazakevich
  • Publisher : John Wiley & Sons
  • Release Date : 2007-02-16
  • Genre: Science
  • Pages : 1080
  • ISBN 10 : 9780470087947

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HPLC for Pharmaceutical Scientists Excerpt :

HPLC for Pharmaceutical Scientists is an excellent book for both novice and experienced pharmaceutical chemists who regularly use HPLC as an analytical tool to solve challenging problems in the pharmaceutical industry. It provides a unified approach to HPLC with an equal and balanced treatment of the theory and practice of HPLC in the pharmaceutical industry. In-depth discussion of retention processes, modern HPLC separation theory, properties of stationary phases and columns are well blended with the practical aspects of fast and effective method development and method validation. Practical and pragmatic approaches and actual examples of effective development of selective and rugged HPLC methods from a physico-chemical point of view are provided. This book elucidates the role of HPLC throughout the entire drug development process from drug candidate inception to marketed drug product and gives detailed specifics of HPLC application in each stage of drug development. The latest advancements and trends in hyphenated and specialized HPLC techniques (LC-MS, LC-NMR, Preparative HPLC, High temperature HPLC, high pressure liquid chromatography) are also discussed.

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques Book

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques


  • Author : Ziad El-Rassi
  • Publisher : Elsevier
  • Release Date : 2021-08-17
  • Genre: Language Arts & Disciplines
  • Pages : 954
  • ISBN 10 : 9780128214473

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Carbohydrate Analysis by Modern Liquid Phase Separation Techniques Excerpt :

Carbohydrate Analysis by Modern Liquid Phase Separation Techniques, Second Edition, presents readers with the various principles of modern liquid phase separation techniques and their contributions to the analysis of complex carbohydrates and glycoconjugates. In a selection of all-new chapters, this fully updated volume covers each technique in detail. The book aims to help analysts solve any of the many practical problems they may face in tackling the analysis of carbohydrates. In addition, it addresses current difficulties that must be resolved in carbohydrate research, thus inspiring further important technological developments to meet these challenges. This is an essential resource for anyone seeking a broad view of the science of carbohydrates and separation techniques. Covers the basic principles of modern liquid phase separation techniques, along with their applications Compiles up-to-date information on the field of carbohydrate analysis, along with updates on separation science Focuses on problems currently faced in carbohydrate analysis and the solutions necessary for further progress

The HPLC Expert Book

The HPLC Expert


  • Author : Stavros Kromidas
  • Publisher : John Wiley & Sons
  • Release Date : 2016-08-08
  • Genre: Science
  • Pages : 378
  • ISBN 10 : 9783527336814

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The HPLC Expert Excerpt :

The rapid development of HPLC instrumentation and technology opens numerous possibilities - and entails new questions. Which column should I choose to obtain best results, which gradient fits to my analytical problem, what are recent and promising trends in detection techniques, what is state of the art regarding LC-MS coupling? All these questions are answered by experts in ten self-contained chapters. Besides these more hardware-related and technical chapters, further related areas of interest are covered: Comparison of recent chromatographic data systems and integration strategies, smart documentation, efficient information search in internet, and tips for a successful FDA inspection. This practical approach offers in a condensed manner recent trends and hints, and will also display the advanced reader mistakes and errors he was not aware of so far.

HPLC Method Development for Pharmaceuticals Book

HPLC Method Development for Pharmaceuticals


  • Author : Satinder Ahuja
  • Publisher : Elsevier
  • Release Date : 2011-09-21
  • Genre: Medical
  • Pages : 532
  • ISBN 10 : 9780080554198

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HPLC Method Development for Pharmaceuticals Excerpt :

High pressure, or high performance, liquid chromatography (HPLC) is the method of choice for checking purity of new drug candidates, monitoring changes during scale up or revision of synthetic procedures, evaluating new formulations, and running control/assurance of the final drug product. HPLC Method Development for Pharmaceuticals provides an extensive overview of modern HPLC method development that addresses these unique concerns. Includes a review and update of the current state of the art and science of HPLC, including theory, modes of HPLC, column chemistry, retention mechanisms, chiral separations, modern instrumentation (including ultrahigh-pressure systems), and sample preparation. Emphasis has been placed on implementation in a pharmaceutical setting and on providing a practical perspective. HPLC Method Development for Pharmaceuticals is intended to be particularly useful for both novice and experienced HPLC method development chemists in the pharmaceutical industry and for managers who are seeking to update their knowledge. Covers the requirements for HPLC in a pharmaceutical setting including strategies for software and hardware validation to allow for use in a regulated laboratory Provides an overview of the pharmaceutical development process (clinical phases, chemical and pharmaceutical development activities) Discusses how HPLC is used in each phase of pharmaceutical development and how methods are developed to support activities in each phase

High Performance Gradient Elution Book
Score: 5
From 1 Ratings

High Performance Gradient Elution


  • Author : Lloyd R. Snyder
  • Publisher : John Wiley & Sons
  • Release Date : 2007-01-09
  • Genre: Science
  • Pages : 496
  • ISBN 10 : 9780470055519

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High Performance Gradient Elution Excerpt :

Gradient elution demystified Of the various ways in which chromatography is applied today, few have been as misunderstood as the technique of gradient elution, which presents many challenges compared to isocratic separation. When properly explained, however, gradient elution can be less difficult to understand and much easier to use than often assumed. Written by two well-known authorities in liquid chromatography, High-Performance Gradient Elution: The Practical Application of the Linear-Solvent-Strength Model takes the mystery out of the practice of gradient elution and helps remove barriers to the practical application of this important separation technique. The book presents a systematic approach to the current understanding of gradient elution, describing theory, methodology, and applications across many of the fields that use liquid chromatography as a primary analytical tool. This up-to-date, practical, and comprehensive treatment of gradient elution: * Provides specific, step-by-step recommendations for developing a gradient separation for any sample * Describes the best approach for troubleshooting problems with gradient methods * Guides the reader on the equipment used for gradient elution * Lists which conditions should be varied first during method development, and explains how to interpret scouting gradients * Explains how to avoid problems in transferring gradient methods With a focus on the use of linear solvent strength (LSS) theory for predicting gradient LC behavior and separations by reversed-phase HPLC, High-Performance Gradient Elution gives every chromatographer access to this useful tool.

Practical HPLC Method Development Book

Practical HPLC Method Development


  • Author : Lloyd R. Snyder
  • Publisher : John Wiley & Sons
  • Release Date : 2012-12-03
  • Genre: Science
  • Pages : 800
  • ISBN 10 : 9781118591512

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Practical HPLC Method Development Excerpt :

This revision brings the reader completely up to date on the evolving methods associated with increasingly more complex sample types analyzed using high-performance liquid chromatography, or HPLC. The book also incorporates updated discussions of many of the fundamental components of HPLC systems and practical issues associated with the use of this analytical method. This edition includes new or expanded treatments of sample preparation, computer assisted method development, as well as biochemical samples, and chiral separations.

Analytical Separation Science  5 Volume Set Book

Analytical Separation Science 5 Volume Set


  • Author : Jared Anderson
  • Publisher : John Wiley & Sons
  • Release Date : 2016-02-29
  • Genre: Science
  • Pages : 2148
  • ISBN 10 : 9783527333745

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Analytical Separation Science 5 Volume Set Excerpt :

Leading the way for analytical chemists developing new techniques. This new comprehensive 5 volume set on separation science provides a much needed research-level text for both academic users and researchers who are working with and developing the most current methods, as well as serving as a valuable resource for graduate and post-graduate students. Comprising of five topical volumes it provides a comprehensive overview of the subject, highlighting aspects that will drive research in this field in the years to come. Volume 1: Liquid Chromatography Volume 2: Special Liquid Chromatography Modes and Capillary Electromigration Techniques Volume 3: Gas, Supercritical and Chiral Chromatography Volume 4: Chromatographic and Related Techniques Volume 5: Sample Treatment, Method Validation, and Applications Key Features: - Comprises over 2,100 pages in 5 volumes – available in print and online - Edited by an international editorial team which has both prominent and experienced senior researchers as well as young and dynamic rising stars - Individual chapters are labeled as either introductory or advanced, in order to guide readers in finding the content at the appropriate level - Fully indexed with cross referencing within and between all 5 volumes

Modern Derivatization Methods for Separation Science Book

Modern Derivatization Methods for Separation Science


  • Author : Toshimasa Toyo'oka
  • Publisher : John Wiley & Sons
  • Release Date : 1999
  • Genre: Science
  • Pages : 316
  • ISBN 10 : UOM:39015046896182

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Modern Derivatization Methods for Separation Science Excerpt :

Includes new derivatizing reagents not covered in similar book by Blau and Halket (Wiley 1993) and not found in any other books to date. A field of increasing importance and significance in separation science. Concentrates on synthesis of derivatives for HPLC and Capillary Electrophoresis, techniques of great interest in the pharmaceutical field.