Estrogens And Memory

Estrogens and Memory

• Author : Karyn M. Frick
• Publisher : Oxford University Press, USA
• Release Date : 2020
• Genre: Psychology
• Pages : 516
• ISBN 10 : 9780190645908

"A book about the influence of estrogens on memory would have been unthinkable as recently as 30 years ago. Although a few small studies in the late 1970's reported a beneficial effect of estrogens on memory in human women (Hackman and Galbraith, 1976; Fedor-Freybergh, 1977), examination of the role of estrogens in memory did not truly capture more widespread attention until the pioneering work of Barbara Sherwin and colleagues in 1988 and beyond. In her initial paper, Sherwin showed that bilateral removal of the ovaries (aka surgical menopause) led to impaired short-term and long-term memory, whereas treatment of surgically menopausal women with estradiol alone, testosterone alone, or estradiol plus testosterone prevented this decline (Sherwin, 1988). As a search for the terms "estrogen" and "memory" in PubMed illustrates, well over 2000 papers have been published on the subject of estrogens and memory in the ensuing decades. The vast majority of these studies have focused on the hippocampus, a bilateral medial temporal lobe structure essential for the formation of episodic memories, particularly those with spatial, contextual, relational, temporal, and recognition components (Olton et al., 1979; Morris et al., 1982; Kim and Fanselow, 1992; Squire, 1992; Cohen and Stackman, 2015; Tonegawa et al., 2015; Eichenbaum, 2017). Although various forms of learning and memory are mediated by numerous brain regions, including the prefrontal cortex, medial temporal lobe cortices, amygdala, striatum, and cerebellum, the hippocampus has received the lion's share of attention due to its central importance for episodic memory formation. Hippocampal damage produces profound retrograde amnesia for facts and events, as well as anterograde amnesia for new information and impairments in spatial navigation (Winocur, 1990; Anagnostaras et al., 2001; Clark et al., 2002; Gilboa et al., 2006). Hippocampal dysfunction in middle-aged and aged subjects is a primary contributor to age-related m

Hormones Cognition and Dementia

• Author : Eef Hogervorst
• Publisher : Cambridge University Press
• Release Date : 2009-09-24
• Genre: Medical
• Pages : null
• ISBN 10 : 9781139483650

A decade ago, oestrogen-containing hormone therapy was viewed as a promising strategy for the prevention and treatment of dementia and age-related cognitive decline. However, treatment trials in women with Alzheimer's disease showed that oestrogens did not reverse cognitive impairment, and clinical trials in healthy older women indicated that oestrogens did not prevent cognitive decline. The Women's Health Initiative Memory Study trial even suggested an increased risk of dementia with treatment late in life. What happened? How are we to understand these findings? What are the implications for middle-aged and older women? What about testosterone, and what about men? And where do we go from here? This book brings together world-renowned experts in basic and clinical research on sex steroids, aging, and cognition to integrate existing findings with emerging new data, and offer challenging hypotheses on these key issues.

Research on the Menopause in the 1990s

• Author : WHO Scientific Group on Research on the Menopause in the 1990s
• Publisher : Unknown
• Release Date : 1996
• Genre: Medical
• Pages : 107
• ISBN 10 : IND:30000055359016

This report reviews current research on the menopause, including studies on its symptons and their treatment, and its effects on the cardiovascular and skeletal systems. It also assesses the relevance of existing data to women in developing countries.

The Female Brain

• Author : Louann Brizendine, M.D.
• Publisher : Harmony
• Release Date : 2007-08-07
• Genre: Science
• Pages : 304
• ISBN 10 : 9780767928410

Since Dr. Brizendine wrote The Female Brain ten years ago, the response has been overwhelming. This New York Times bestseller has been translated into more than thirty languages, has sold nearly a million copies between editions, and has most recently inspired a romantic comedy starring Whitney Cummings and Sofia Vergara. And its profound scientific understanding of the nature and experience of the female brain continues to guide women as they pass through life stages, to help men better understand the girls and women in their lives, and to illuminate the delicate emotional machinery of a love relationship. Why are women more verbal than men? Why do women remember details of fights that men can’t remember at all? Why do women tend to form deeper bonds with their female friends than men do with their male counterparts? These and other questions have stumped both sexes throughout the ages. Now, pioneering neuropsychiatrist Louann Brizendine, M.D., brings together the latest findings to show how the unique structure of the female brain determines how women think, what they value, how they communicate, and who they love. While doing research as a medical student at Yale and then as a resident and faculty member at Harvard, Louann Brizendine discovered that almost all of the clinical data in existence on neurology, psychology, and neurobiology focused exclusively on males. In response to the overwhelming need for information on the female mind, Brizendine established the first clinic in the country to study and treat women’s brain function. In The Female Brain, Dr. Brizendine distills all her findings and the latest information from the scientific community in a highly accessible book that educates women about their unique brain/body/behavior. The result: women will come away from this book knowing that they have a lean, mean, communicating machine. Men will develop a serious case of brain envy.

Sex Hormones in Neurodegenerative Processes and Diseases

• Author : Gorazd Drevensek
• Publisher : BoD – Books on Demand
• Release Date : 2018-05-02
• Genre: Medical
• Pages : 358
• ISBN 10 : 9781789230147

The book provides chapters on sex hormones and their modulation in neurodegenerative processes and pathologies, from basic molecular mechanisms, physiology, gender differences, to neuroprotection and clinical aspects for potential novel pharmacotherapy approaches. The book contains 14 chapters written by authors from various biomedical professions, from basic researchers in biology and physiology to medicine and veterinary medicine, pharmacologists, psychiatrist, etc. Chapters sum up the past and current knowledge on sex hormones, representing original new insights into their role in brain functioning, mental disorders and neurodegenerative diseases. The book is written for a broad range of audience, from biomedical students to highly profiled medical specialists and biomedical researchers, helping them to expand their knowledge on sex hormones in neurodegenerative processes and opening new questions for further investigation.

The Good News About Estrogen

• Author : Uzzi Reiss, M.D.
• Publisher : St. Martin's Press
• Release Date : 2020-03-10
• Genre: Health & Fitness
• Pages : 320
• ISBN 10 : 9781250214546

The latest information about estrogen, the body's enlivening powerhouse hormone. Why is estrogen crucial—and so misunderstood? How do I know if my estrogen level is “normal”? What is the best treatment for a hormonal imbalance? How does estrogen impact my reproductive cycle? Is hormone replacement therapy right for me? Is it only useful at menopause? How can I be my best, healthiest self now and in the future? Understanding estrogen—its function and interplay with all your other hormones and body systems—is key to a healthy, vibrant life. But far too many women remain unaware of the benefits of estrogen, and how it can be supplemented in natural, bioidentical form. This book, written by an expert in the field of OB-GYN and integrative medicine, offers an authoritative yet accessible approach to hormonal health. In The Good News About Estrogen, Dr. Uzzi Reiss draws upon the most up-to-date scientific research, as well as women’s stories from his decades of practice, to explain: - How hormones—and your levels of estrogen—change over time, and what you can do to achieve balance naturally or with hormone replacement therapy (HRT). - The good news about estrogen—how it can enhance energy, sexuality, and memory; alleviate premenstrual syndrome (PMS) or the side effects of menopause; help fight weight gain, anxiety, depression, and more. - Bioidentical hormones—why they are safe and crucial to your well-being at any age or stage, and how to choose which treatment plan is right for you. - How your everyday habits—what you eat, drink, wear, and breathe—can affect hormonal health, and which small lifestyle changes can make a big difference. - Nutrition and exercise—learn how each works hand-in-hand with hormones and can help you to achieve maximum physical and emotional fitness, promote bone health, prevent cardiovascular disease, and boost brain power.

Neural Plasticity and Memory

• Author : Federico Bermudez-Rattoni
• Publisher : CRC Press
• Release Date : 2007-04-17
• Genre: Science
• Pages : 368
• ISBN 10 : 1420008412

A comprehensive, multidisciplinary review, Neural Plasticity and Memory: From Genes to Brain Imaging provides an in-depth, up-to-date analysis of the study of the neurobiology of memory. Leading specialists share their scientific experience in the field, covering a wide range of topics where molecular, genetic, behavioral, and brain imaging techniques have been used to investigate how cellular and brain circuits may be modified by experience. In each chapter, researchers present findings and explain their innovative methodologies. The book begins by introducing key issues and providing a historical overview of the field of memory consolidation. The following chapters review the putative genetic and molecular mechanisms of cell plasticity, elaborating on how experience could induce gene and protein expression and describing their role in synaptic plasticity underlying memory formation. They explore how putative modifications of brain circuits and synaptic elements through experience can become relatively permanent and hence improve brain function. Interdisciplinary reviews focus on how nerve cell circuitry, molecular expression, neurotransmitter release, and electrical activity are modified during the acquisition and consolidation of long-term memory. The book also covers receptor activation/deactivation by different neurotransmitters that enable the intracellular activation of second messengers during memory formation. It concludes with a summary of current research on the modulation and regulation that different neurotransmitters and stress hormones have on formation and consolidation of memory.

Hormones Brain and Behavior Five Volume Set

• Author : Anonim
• Publisher : Elsevier
• Release Date : 2002-06-18
• Genre: Medical
• Pages : 4393
• ISBN 10 : 9780080534152

Hormones, Brain and Behavior, Third Edition offers a state-of-the-art overview of hormonally-mediated behaviors, including an extensive discussion of the effects of hormones on insects, fish, amphibians, birds, rodents, and humans. Entries have been carefully designed to provide a valuable source of information for students and researchers in neuroendocrinology and those working in related areas, such as biology, psychology, psychiatry, and neurology. This third edition has been substantially restructured to include both foundational information and recent developments in the field. Continuing the emphasis on interdisciplinary research and practical applications, the book includes articles aligned in five main subject sections, with new chapters included on genetic and genomic techniques and clinical investigations. This reference provides unique treatment of all major vertebrate and invertebrate model systems with excellent opportunities for relating behavior to molecular genetics. The topics cover an unusual breadth (from molecules to ecophysiology), ranging from basic science to clinical research, making this reference of interest to a broad range of scientists in a variety of fields. Key Features * Contributors from 16 different countries and more than 70 institutions * Unlike any other hormone reference on the market Hormones, Brain and Behavior addresses hormone effects in all major vertebrate and non-vertebrate models * A timely, current reference on an emerging field with each chapter providing an in-depth exploration of the topic * Discusses molecular aspects of hormone function, systems, development, and hormone-related diseases * Addresses hormone effects in both the developing and adult nervous system Topics include: * Mammalian and Non-mammalian Hormone-behavior Systems * Cellular and Molecular Mechanisms of Hormone Actions on Behavior * Development of Hormone-dependent Neuronal Systems * Hormone/Behavior Relations of Clinical Importance

Hormonal Restructuring of the Adult Brain

• Author : Victoria Nall Luine
• Publisher : Unknown
• Release Date : 1994
• Genre: Brain
• Pages : 273
• ISBN 10 : OCLC:1149480509

The Relationship Between Estrogen and Memory in Healthy Postmenopausal Women and Women in the Early Stages of Alzheimer s Disease

• Author : Diane L. Kampen
• Publisher : Unknown
• Release Date : 1993
• Genre: Alzheimer's disease
• Pages : 322
• ISBN 10 : OCLC:427912455

"The effects of exogenous estrogen administration on aspects of memory and cognition in women were examined in two studies. In Study 1, women receiving estrogen replacement therapy were compared to untreated women on four measures of verbal memory. Those receiving estrogen had significantly better scores on a measure of delayed memory for propositional material. In Study 2, women in the early stages of Alzheimer's Disease (AD) were administered either estrogen or placebo on a double-blind basis for six months. Women given estrogen showed improvement on a measure of verbal memory and spatial attention compared to the placebo controls. The combined results of these studies provide evidence that estrogen enhances aspects of verbal memory in both healthy postmenopausal women and in postmenopausal women in the early stages of AD as measured by neuropsychological tests. These effects might be mediated by actions of estrogen on neuronal morphology and physiology in brain areas important for memory and cognition." --

The Menopause Manifesto

• Author : Dr. Jen Gunter
• Publisher : Random House Canada
• Release Date : 2021-05-25
• Genre: Medical
• Pages : 400
• ISBN 10 : 9780735280793

#1 NATIONAL BESTSELLER In her follow-up to the #1 bestseller The Vagina Bible, Dr. Jen Gunter, Canadian OB/GYN and the internet's most fearless advocate for women's health, brings us empowerment through knowledge by countering stubborn myths and misunderstandings about menopause with hard facts, real science, fascinating historical perspective, and expert advice. The only thing predictable about menopause is its unpredictability. Factor in widespread misinformation, a lack of research, and the culture of shame around women's bodies, and it's no wonder women are unsure what to expect during the menopause transition and beyond. Menopause is not a disease--it's a planned change, like puberty. And just like puberty, we should be educated on what's to come years in advance, rather than the current practice of leaving people on their own with bothersome symptoms and too much conflicting information. Knowing what is happening, why, and what to do about it is both empowering and reassuring. Frank and funny, Dr. Jen debunks misogynistic attitudes and challenges the over-mystification of menopause to reveal everything you really need to know about: * Perimenopause * Hot flashes * Sleep disruption * Sex and libido * Depression and mood changes * Skin and hair issues * Outdated therapies * Breast health * Weight and muscle mass * Health maintenance screening * And much more! Filled with practical tips, useful information and startling insights, this essential guide will revolutionize how women experience menopause--and show them how their lives can be even better for it.

Hormones Cognition and Dementia

• Author : Eef Hogervorst
• Publisher : Cambridge University Press
• Release Date : 2009-09-24
• Genre: Medical
• Pages : 280
• ISBN 10 : 9780521899376

Basic and clinical research on sex steroids, ageing, and cognition to integrate existing findings with emerging data.

The XX Brain

• Author : Lisa Mosconi
• Publisher : Atlantic Books
• Release Date : 2020-06-04
• Genre: Health & Fitness
• Pages : 289
• ISBN 10 : 9781760870829

Women are far more likely than men to suffer from anxiety, depression, migraines, brain injuries, strokes and Alzheimer's disease. But, until recently, scientific research has focused on 'bikini medicine,' assuming that women are essentially men with different reproductive organs. The XX Brain presents groundbreaking research showing that women's brains age distinctly from men's, due mostly to the decline of a key brain-protective hormone: estrogen. Taking on all aspects of women's health, including brain fog, memory lapses, depression, stress, insomnia, hormonal imbalances and the increased risk of dementia, Dr. Mosconi introduces cutting-edge, evidence-based methods for protecting the female brain, encompassing diet, stress reduction and sleep. She also examines the effectiveness of hormonal replacement therapy, addresses the perils of environmental toxins and explores the role of our microbiome. Luckily, it is never too late to take care of yourself.

Estrogen Matters

• Author : Carol Tavris
• Publisher : Hachette UK
• Release Date : 2018-09-04
• Genre: Health & Fitness
• Pages : 320
• ISBN 10 : 9780316481182

A compelling defense of hormone replacement therapy, exposing the faulty science behind its fall from prominence and empowering women to make informed decisions about their health. For years, hormone replacement therapy (HRT) was hailed as a miracle. Study after study showed that HRT, if initiated at the onset of menopause, could ease symptoms ranging from hot flashes to memory loss; reduce the risk of heart disease, Alzheimer's, osteoporosis, and some cancers; and even extend a woman's overall life expectancy. But when a large study by the Women's Health Initiative announced results showing an uptick in breast cancer among women taking HRT, the winds shifted abruptly, and HRT, officially deemed a carcinogen, was abandoned. Now, sixteen years after HRT was left for dead, Dr. Bluming, a medical oncologist, and Dr. Tavris, a social psychologist, track its strange history and present a compelling case for its resurrection. They investigate what led the public -- and much of the medical establishment -- to accept the Women's Health Initiative's often exaggerated claims, while also providing a fuller picture of the science that supports HRT. A sobering and revelatory read, Estrogen Matters sets the record straight on this beneficial treatment and provides an empowering path to wellness for women everywhere.

The Maze Book

• Author : Heather A. Bimonte-Nelson
• Publisher : Humana Press
• Release Date : 2015-03-11
• Genre: Medical
• Pages : 457
• ISBN 10 : 1493921584

This vibrant collection delivers a laboratory roadmap of testing cognition in the rodent. While rodents and mazes are the main center and focus of this book, many aspects in the field of learning and memory are discussed and detailed, spanning from the molecular to the human, with every chapter delivering a comprehensive review of historical milestones in order to provide context for past discoveries, new findings, and future studies. Didactic foundations, operational definitions, and theory, as well as practical experimental and apparatus set-up, data analysis, and interpretation instructions are included in the first part of the book, while part two contains step-by-step protocols, troubleshooting, and tips from experts in the field. Authoritative and inspirational, The Maze Book: Theories, Practice, and Protocols for Testing Rodent Cognition serves as a detailed and practical manual for scientists wishing to implement these tools in their laboratories and for scholars interested in this powerful field.