Eukaryotic Transcription Factors Book

Eukaryotic Transcription Factors


  • Author : David Latchman
  • Publisher : Academic Press
  • Release Date : 2010-07-28
  • Genre: Science
  • Pages : 488
  • ISBN 10 : 0080561039

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Eukaryotic Transcription Factors Book Description :

Transcription, or the process by which DNA produces RNA, is a central aspect of gene expression. Transcription factors regulate transcription during development and in disease states. As such, it is critical for researchers to gain a good understanding of the relationship between the structure of various families of transcription factors and their function, as well as roles in human disease. Since publication of the Fourth Edition, there have been major advances, notably in the areas of chromatin remodeling and genome-scale analyses. This complete update includes all new coverage of the latest developments, from enabling genomic technologies to studies on the importance of post-translational modifications beyond phosphorylation events. Potential of transcription factors as therapeutic targets in human disease Importance of histone modifications Use of genome-based sequence analysis and high-throughput methods Applications of the chromatin immunoprecipitation (ChIP) assay Transcriptional elongation Regulation by post-translational modifications Regulatory networks and bioinformatics

Eukaryotic Transcription Factors Book

Eukaryotic Transcription Factors


  • Author : David S. Latchman
  • Publisher :
  • Release Date : 1995
  • Genre: DNA-protein interactions
  • Pages : 325
  • ISBN 10 : UOM:39076001892665

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Eukaryotic Transcription Factors Book Description :

"Understanding the mechanisms of eukaryotic gene regulation is essential for students and scientists working in a wide range of clinical and basic disciplines. However, keeping track of the vast number of transcription factors which are central to gene regulation can prove daunting. The fourth edition of Eukaryotic Transcription Factors not only provides the reader with a clear and concise understanding of transcription factors but also of their vital role in the regulation of transcription in different cell types during development, in response to specific stimuli and in disease."--BOOK JACKET.

A Handbook of Transcription Factors Book

A Handbook of Transcription Factors


  • Author : Timothy R. Hughes
  • Publisher : Springer Science & Business Media
  • Release Date : 2011-05-10
  • Genre: Medical
  • Pages : 306
  • ISBN 10 : 904819069X

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A Handbook of Transcription Factors Book Description :

Transcription factors are the molecules that the cell uses to interpret the genome: they possess sequence-specific DNA-binding activity, and either directly or indirectly influence the transcription of genes. In aggregate, transcription factors control gene expression and genome organization, and play a pivotal role in many aspects of physiology and evolution. This book provides a reference for major aspects of transcription factor function, encompassing a general catalogue of known transcription factor classes, origins and evolution of specific transcription factor types, methods for studying transcription factor binding sites in vitro, in vivo, and in silico, and mechanisms of interaction with chromatin and RNA polymerase.

Eukaryotic Transcription Factors Book

Eukaryotic Transcription Factors


  • Author : David S. Latchman
  • Publisher :
  • Release Date : 1998-11-30
  • Genre:
  • Pages : 325
  • ISBN 10 : 0132471760

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Eukaryotic Transcription Factors Book Description :

The third edition of Eukaryotic Transcription Factors has been rewritten to reflect advances in the field. These include the emerging roles of specific co-activator molecules such as CBP in the action of a number of different transcription factors emphasising particularly their ability to modulate chromatin structure.

Gene Control Book

Gene Control


  • Author : David Latchman
  • Publisher : Garland Science
  • Release Date : 2018-03-29
  • Genre: Science
  • Pages : 448
  • ISBN 10 : 9781136844201

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Gene Control Book Description :

Gene Control offers a current description of how gene expression is controlled in eukaryotes, reviewing and summarizing the extensive primary literature into an easily accessible format. Gene Control is a comprehensively restructured and expanded edition of Latchman’s Gene Regulation: A Eukaryotic Perspective, Fifth Edition. The first part of the book deals with the fundamental processes of gene control at the levels of chromatin structure, transcription, and post-transcriptional processes. Three pairs of chapters deal with each of these aspects, first describing the basic process itself, followed by the manner in which it is involved in controlling gene expression. The second part of the book deals with the role of gene control in specific biological processes. Certain chapters deal with the importance of gene control in cellular signaling processes and for normal development of the embryo. Another chapter discusses the key roles played by gene-regulatory processes in the specification of differentiated cell types such as muscle cells and neurons. The final chapters discuss the consequences of errors in gene control; the relationship between gene misregulation and human diseases, especially cancer; and potential therapies designed specifically to target particular levels of gene control. Gene Control will be of value to students in biological sciences, as well as to scientists and clinicians interested in how genes are regulated in health and disease.

Biology 2e Book

Biology 2e


  • Author : Mary Ann Clark
  • Publisher :
  • Release Date : 2018
  • Genre: Biology
  • Pages : 1567
  • ISBN 10 : OCLC:1044735448

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Biology 2e Book Description :

Biology 2e (2nd edition) is designed to cover the scope and sequence requirements of a typical two-semester biology course for science majors. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology includes rich features that engage students in scientific inquiry, highlight careers in the biological sciences, and offer everyday applications. The book also includes various types of practice and homework questions that help students understand -- and apply -- key concepts. The 2nd edition has been revised to incorporate clearer, more current, and more dynamic explanations, while maintaining the same organization as the first edition. Art and illustrations have been substantially improved, and the textbook features additional assessments and related resources.

Plant Transcription Factors Book

Plant Transcription Factors


  • Author : Daniel H Gonzalez
  • Publisher : Academic Press
  • Release Date : 2015-07-07
  • Genre: Science
  • Pages : 434
  • ISBN 10 : 9780128011270

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Plant Transcription Factors Book Description :

Plant Transcription Factors: Evolutionary, Structural and Functional Aspects is the only publication that provides a comprehensive compilation of plant transcription factor families and their complex roles in plant biology. While the majority of information about transcription factors is based on mammalian systems, this publication discusses plant transcription factors, including the important aspects and unifying themes to understanding transcription factors and the important roles of particular families in specific processes. Provides an entry point for transcription factor literature Offers compilation of information into one single resource for rapid consultation on different plant transcription factor features Integrates the knowledge about different transcription factors, along with cross-referencing Provides information on the unique aspects surrounding plant transcription factors

Biology for AP    Courses Book

Biology for AP Courses


  • Author : Julianne Zedalis
  • Publisher :
  • Release Date : 2017-10-16
  • Genre: Biology
  • Pages : 1923
  • ISBN 10 : 1947172409

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Biology for AP Courses Book Description :

Biology for AP® courses covers the scope and sequence requirements of a typical two-semester Advanced Placement® biology course. The text provides comprehensive coverage of foundational research and core biology concepts through an evolutionary lens. Biology for AP® Courses was designed to meet and exceed the requirements of the College Board’s AP® Biology framework while allowing significant flexibility for instructors. Each section of the book includes an introduction based on the AP® curriculum and includes rich features that engage students in scientific practice and AP® test preparation; it also highlights careers and research opportunities in biological sciences.

Gene Regulation in Eukaryotes Book

Gene Regulation in Eukaryotes


  • Author : Edgar Wingender
  • Publisher : Wiley-Blackwell
  • Release Date : 1993
  • Genre: Science
  • Pages : 430
  • ISBN 10 : UOM:39015029969725

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Gene Regulation in Eukaryotes Book Description :

A much-needed guide through the overwhelming amount of literature in the field. Comprehensive and detailed, this book combines background information with the most recentinsights. It introduces current concepts, emphasizing the transcriptional control of genetic information. Moreover, it links data on the structure of regulatory proteins with basic cellular processes. Both advanced students and experts will find answers to such intriguing questions as: - How are programs of specific gene repertoires activated and controlled? - Which genes drive and control morphogenesis? - Which genes govern tissue-specific tasks? - How do hormones control gene expression in coordinating the activities of different tissues? An abundant number of clearly presented glossary terms facilitates understanding of the biological background. Speacial feature: over 2200 (!) literature references.

Protein Dimerization and Oligomerization in Biology Book

Protein Dimerization and Oligomerization in Biology


  • Author : Jacqueline M. Matthews
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-09-04
  • Genre: Medical
  • Pages : 170
  • ISBN 10 : 9781461432296

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Protein Dimerization and Oligomerization in Biology Book Description :

This volume has a strong focus on homo-oligomerization, which is surprisingly common. However, protein function is so often linked to both homo- and hetero-oligomerization and many heterologous interactions likely evolved from homologous interaction, so this volume also covers many aspects of hetero-oligomerization.

Transcriptional and Post transcriptional Regulation Book

Transcriptional and Post transcriptional Regulation


  • Author : Ghedira Kais
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-10-10
  • Genre: Medical
  • Pages : 134
  • ISBN 10 : 9781789237917

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Transcriptional and Post transcriptional Regulation Book Description :

This book focuses on the transcriptional and post-transcriptional gene regulations and presents a detailed portrait of many novel aspects related to highlighting the importance of key TFs in some vital biological processes, the role of certain TFs to control some infectious diseases, the role of non-coding RNAs in controlling mRNA expression, the involvement of these non-coding RNAs in diseases, and the interplay between TFs and microRNAs as key players for gene expression regulation giving a complete picture of how genes are regulated at the cellular level. The editor embarked upon this writing project entitled "Transcriptional and Post-transcriptional Regulation" to make pertinent contributions accessible to the scientific community. Hopefully, a large audience will enjoy reading and benefit from the chapters of this book.

Mechanisms of Gene Expression Book

Mechanisms of Gene Expression


  • Author : Robert O J Weinzierl
  • Publisher : World Scientific
  • Release Date : 1999-08-10
  • Genre: Science
  • Pages : 436
  • ISBN 10 : 9781783262250

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Mechanisms of Gene Expression Book Description :

A detailed knowledge of the mechanisms underlying the transcriptional control of gene expression is of fundamental importance to many areas of contemporary biomedical research, ranging from understanding basic issues (such as control of embryonic development) to practical applications in industry and medicine. Although elementary concepts of gene expression are described in all general molecular biology textbooks, the depth of coverage is often rather limited and recent discoveries are sometimes not adequately taken into consideration. This book presents much of the current thinking concerning molecular mechanisms of transcriptional control in a form easily accessible to undergraduates with an understanding of basic molecular biology concepts. It contains detailed information about the various pro- and eukaryotic transcriptional machineries that has recently become available through the combined efforts of geneticists, biochemists and structural biologists. The book will thus not only serve as an undergraduate text but also offer something new and interesting to more advanced readers and professional scientists who want to keep up to date with rapid advances in this field. Contents:RNA PolymerasesBasal Factors Recognize Promoters and Assemble the Pre-Initiation Transcription ComplexesGene-Specific Transcription FactorsCoactivators: Interface between Gene-Specific and Basal Transcription FactorsControl of RNA Elongation and TerminationRNAPI and RNAPIII Transcriptional MachineriesChromatinNuclear Matrix, Chromosome Scaffolds and Transcriptional FactoriesGene Expression Dynamics and Global Genome Transcription PatternsAppearing on the Horizon: Medical Applications Focusing on Transcriptional Control Mechanisms Readership: Undergraduate and graduate students in molecular biology, biochemistry and genetics. Keywords:Gene Expression;Genetics;Mechanisms;Basal Transcriptional Machinery

Mechanisms of Transcription Book

Mechanisms of Transcription


  • Author : Fritz Eckstein
  • Publisher : Springer
  • Release Date : 2011-10-03
  • Genre: Science
  • Pages : 327
  • ISBN 10 : 3642645097

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Mechanisms of Transcription Book Description :

Mechanisms of Transcription presents a unique perspective on the fundamental processes of transcription. A collection of distinguished authors draws together the underlying mechanisms involved in the process of transcription. This includes RNA polymerase function and its interaction with promoter sequences, and the structures of the various components on the transcriptional machinery. Both prokaryotic and eukaryotic systems, NMR and crystallographic structures of a number of important eukaryotic transcription factors are discussed, as well as the role of chromatin structure.

Gene Regulation Book
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Gene Regulation


  • Author : David Latchman
  • Publisher : Garland Science
  • Release Date : 2007-01-25
  • Genre: Medical
  • Pages : 359
  • ISBN 10 : 9780203016336

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Gene Regulation Book Description :

Gene regulation is an essential process in the development and maintenance of a healthy body, and as such, is a central focus in both basic science and medical research. Gene Regulation, Fifth Edition provides the student and researcher with a clear, up-to-date description of gene regulation in eukaryotes, distilling the vast and complex primary literature into a concise overview.

Mechanisms of Gene Regulation Book

Mechanisms of Gene Regulation


  • Author : Carsten Carlberg
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-12-11
  • Genre: Medical
  • Pages : 210
  • ISBN 10 : 9789400779051

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Mechanisms of Gene Regulation Book Description :

This textbook aims to describe the fascinating area of eukaryotic gene regulation for graduate students in all areas of the biomedical sciences. Gene expression is essential in shaping the various phenotypes of cells and tissues and as such, regulation of expression is a fundamental aspect of nearly all processes in physiology, both in healthy and in diseased states. This pivotal role for the regulation of gene expression makes this textbook essential reading from students of all the biomedical sciences in order to be better prepared for their specialized disciplines. A complete understanding of transcription factors and the processes that alter their activity is a major goal of modern life science research. The availability of the whole human genome sequence (and that of other eukaryotic genomes) and the consequent development of next-generation sequencing technologies have significantly changed nearly all areas of the biological sciences. For example, the genome-wide location of histone modifications and transcription factor binding sites, such as provided by the ENCODE consortium, has greatly improved our understanding of gene regulation. Therefore, the focus of this book is the description of the post-genome understanding of gene regulation. The purpose of this book is to provide, in a condensed form, an overview on the present understanding of the mechanisms of gene regulation. The authors are not aiming to compete with comprehensive treatises, but rather focus on the essentials. Therefore, the authors have favored a high figure-to-text ratio following the rule which states that “a picture tells more than thousand words”. The content of the book is based on the lecture course, which is given by Prof. Carlberg since 2001 at the University of Eastern Finland in Kuopio. The book is subdivided into 4 sections and 13 chapters. Following the Introduction there are three sections, which take a view on gene regulation from the perspective of transcription factors,