Evolution by Tumor Neofunctionalization Book

Evolution by Tumor Neofunctionalization


  • Author : Andrei P. Kozlov
  • Publisher : Academic Press
  • Release Date : 2014-02-15
  • Genre: Science
  • Pages : 248
  • ISBN 10 : 9780128004982

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Evolution by Tumor Neofunctionalization Book Description :

Evolution by Tumor Neofunctionalization explores the possibility of the positive role of tumors in evolution of multicellular organisms. This unique perspective goes beyond recent publications on how evolution may influence tumors, to consider the possible role of tumors in evolution. Widespread in nature tumors represent a much broader category than malignant tumors only. The majority of tumors in humans and other animals may never undergo malignant transformation. Tumors may differentiate with the loss of malignancy, and malignant tumors may spontaneously regress. Cellular oncogenes and tumor suppressor genes play roles in normal development. Many features of tumors could be used in evolution, and there are examples of tumors that have played a role in evolution. This book will stimulate thinking on this topic by specialists in the fields of evolutionary biology, oncology, molecular biology, molecular evolution, embryology, evo-devo, tumor immunology, pathology and clinical oncology. Covers the role that tumors might play in evolution. Provides multidisciplinary approach that will appeal to a wide circle of professionals in the fields of evolutionary biology, oncology, molecular biology, and more

Macroevolution Book

Macroevolution


  • Author : Emanuele Serrelli
  • Publisher : Springer
  • Release Date : 2015-02-13
  • Genre: Science
  • Pages : 403
  • ISBN 10 : 9783319150451

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Macroevolution Book Description :

This book is divided in two parts, the first of which shows how, beyond paleontology and systematics, macroevolutionary theories apply key insights from ecology and biogeography, developmental biology, biophysics, molecular phylogenetics and even the sociocultural sciences to explain evolution in deep time. In the second part, the phenomenon of macroevolution is examined with the help of real life-history case studies on the evolution of eukaryotic sex, the formation of anatomical form and body-plans, extinction and speciation events of marine invertebrates, hominin evolution and species conservation ethics. The book brings together leading experts, who explain pivotal concepts such as Punctuated Equilibria, Stasis, Developmental Constraints, Adaptive Radiations, Habitat Tracking, Turnovers, (Mass) Extinctions, Species Sorting, Major Transitions, Trends and Hierarchies – key premises that allow macroevolutionary epistemic frameworks to transcend microevolutionary theories that focus on genetic variation, selection, migration and fitness. Along the way, the contributing authors review ongoing debates and current scientific challenges; detail new and fascinating scientific tools and techniques that allow us to cross the classic borders between disciplines; demonstrate how their theories make it possible to extend the Modern Synthesis; present guidelines on how the macroevolutionary field could be further developed; and provide a rich view of just how it was that life evolved across time and space. In short, this book is a must-read for active scholars and because the technical aspects are fully explained, it is also accessible for non-specialists. Understanding evolution requires a solid grasp of above-population phenomena. Species are real biological individuals and abiotic factors impact the future course of evolution. Beyond observation, when the explanation of macroevolution is the goal, we need both evidence and theory that enable us to explain and interpret ho

Progress in Botany Vol  81 Book

Progress in Botany Vol 81


  • Author : Francisco M. Cánovas
  • Publisher : Springer Nature
  • Release Date :
  • Genre:
  • Pages :
  • ISBN 10 : 9783030363277

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Progress in Botany Vol 81 Book Description :

Breadmaking Book

Breadmaking


  • Author : S P Cauvain
  • Publisher : Elsevier
  • Release Date : 2012-04-25
  • Genre: Technology & Engineering
  • Pages : 832
  • ISBN 10 : 9780857095695

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Breadmaking Book Description :

The first edition of Breadmaking: Improving quality quickly established itself as an essential purchase for baking professionals and researchers in this area. With comprehensively updated and revised coverage, including six new chapters, the second edition helps readers to understand the latest developments in bread making science and practice. The book opens with two introductory chapters providing an overview of the breadmaking process. Part one focuses on the impacts of wheat and flour quality on bread, covering topics such as wheat chemistry, wheat starch structure, grain quality assessment, milling and wheat breeding. Part two covers dough development and bread ingredients, with chapters on dough aeration and rheology, the use of redox agents and enzymes in breadmaking and water control, among other topics. In part three, the focus shifts to bread sensory quality, shelf life and safety. Topics covered include bread aroma, staling and contamination. Finally, part four looks at particular bread products such as high fibre breads, those made from partially baked and frozen dough and those made from non-wheat flours. With its distinguished editor and international team of contributors, the second edition of Breadmaking: Improving quality is a standard reference for researchers and professionals in the bread industry and all those involved in academic research on breadmaking science and practice. With comprehensively updated and revised coverage, this second edition outlines the latest developments in breadmaking science and practice Covers topics such as wheat chemistry, wheat starch structure, grain quality assessment, milling and wheat breeding Discusses dough development and bread ingredients, with chapters on dough aeration and rheology

Venoms   Advances in Research and Application  2013 Edition Book

Venoms Advances in Research and Application 2013 Edition


  • Author :
  • Publisher : ScholarlyEditions
  • Release Date : 2013-06-21
  • Genre: Medical
  • Pages : 69
  • ISBN 10 : 9781481681148

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Venoms Advances in Research and Application 2013 Edition Book Description :

Venoms—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Snake Venoms in a concise format. The editors have built Venoms—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Snake Venoms in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Venoms—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

Evolution Driven by Organismal Behavior Book

Evolution Driven by Organismal Behavior


  • Author : Rui Diogo
  • Publisher : Springer
  • Release Date : 2017-03-08
  • Genre: Science
  • Pages : 252
  • ISBN 10 : 9783319475813

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Evolution Driven by Organismal Behavior Book Description :

This book proposes a new way to think about evolution. The author carefully brings together evidence from diverse fields of science. In the process, he bridges the gaps between many different--and usually seen as conflicting--ideas to present one integrative theory named ONCE, which stands for Organic Nonoptimal Constrained Evolution. The author argues that evolution is mainly driven by the behavioral choices and persistence of organisms themselves, in a process in which Darwinian natural selection is mainly a secondary--but still crucial--evolutionary player. Within ONCE, evolution is therefore generally made of mistakes and mismatches and trial-and-error situations, and is not a process where organisms engage in an incessant, suffocating struggle in which they can't thrive if they are not optimally adapted to their habitats and the external environment. Therefore, this unifying view incorporates a more comprehensive view of the diversity and complexity of life by stressing that organisms are not merely passive evolutionary players under the rule of external factors. This insightful and well-reasoned argument is based on numerous fascinating case studies from a wide range of organisms, including bacteria, plants, insects and diverse examples from the evolution of our own species. The book has an appeal to researchers, students, teachers, and those with an interest in the history and philosophy of science, as well as to the broader public, as it brings life back into biology by emphasizing that organisms, including humans, are the key active players in evolution and thus in the future of life on this wonderful planet.

Homology  Genes  and Evolutionary Innovation Book

Homology Genes and Evolutionary Innovation


  • Author : Günter P. Wagner
  • Publisher : Princeton University Press
  • Release Date : 2018-07-10
  • Genre: Science
  • Pages : 496
  • ISBN 10 : 9780691180670

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Homology Genes and Evolutionary Innovation Book Description :

A major synthesis of homology, written by a top researcher in the field Homology—a similar trait shared by different species and derived from common ancestry, such as a seal's fin and a bird’s wing—is one of the most fundamental yet challenging concepts in evolutionary biology. This groundbreaking book provides the first mechanistically based theory of what homology is and how it arises in evolution. Günter Wagner, one of the preeminent researchers in the field, argues that homology, or character identity, can be explained through the historical continuity of character identity networks—that is, the gene regulatory networks that enable differential gene expression. He shows how character identity is independent of the form and function of the character itself because the same network can activate different effector genes and thus control the development of different shapes, sizes, and qualities of the character. Demonstrating how this theoretical model can provide a foundation for understanding the evolutionary origin of novel characters, Wagner applies it to the origin and evolution of specific systems, such as cell types; skin, hair, and feathers; limbs and digits; and flowers. The first major synthesis of homology to be published in decades, Homology, Genes, and Evolutionary Innovation reveals how a mechanistically based theory can serve as a unifying concept for any branch of science concerned with the structure and development of organisms, and how it can help explain major transitions in evolution and broad patterns of biological diversity.

Genome Evolution Book

Genome Evolution


  • Author : Axel Meyer
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-04-30
  • Genre: Medical
  • Pages : 237
  • ISBN 10 : 1402010214

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Genome Evolution Book Description :

Table of contents

Vaccines for Cancer Immunotherapy Book

Vaccines for Cancer Immunotherapy


  • Author : Nima Rezaei
  • Publisher : Academic Press
  • Release Date : 2018-10-17
  • Genre: Medical
  • Pages : 198
  • ISBN 10 : 9780128140406

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Vaccines for Cancer Immunotherapy Book Description :

Therapeutic cancer vaccines represent a type of active cancer immunotherapy. Clinicians, scientists, and researchers working on cancer treatment require evidence-based and up-to-date resources relating to therapeutic cancer vaccines. Vaccines for Cancer Immunotherapy provides a reference for cancer treatment for clinicians and presents a well-organized resource for determining high-potential research areas. The book considers that this promising modality can be made more feasible as a treatment for cancer. Chapters cover cancer immunology, general approaches to cancer immunotherapy, vaccines, tumor antigens, the strategy of allogeneic and autologous cancer vaccines, personalized vaccines, whole-tumor antigen vaccines, protein and peptide vaccines, dendritic cell vaccines, genetic vaccines, candidate cancers for vaccination, obstacles to developing therapeutic cancer vaccines, combination therapy, future perspectives and concluding remarks on therapeutic cancer vaccines. Introduces the feasible immunotherapeutic vaccines for patients with different types of cancer Presents the status of past and current vaccines for cancer treatment Considers advantages and disadvantages of different therapeutic cancer vaccines Looks at the combination of vaccines and other modalities, including immunotherapeutic and conventional methods Analyzes obstacles to development of therapeutic cancer vaccines Gives a view on future perspectives in the application of therapeutic cancer vaccines

Epigenetics Territory and Cancer Book

Epigenetics Territory and Cancer


  • Author : Parvin Mehdipour
  • Publisher : Springer
  • Release Date : 2015-03-18
  • Genre: Medical
  • Pages : 539
  • ISBN 10 : 9789401796392

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Epigenetics Territory and Cancer Book Description :

This book explores epigenetic strategies, bridging fundamental cancer epigenetics, different paradigms in tumor genetics and translational understanding for both the clinic and improved lifestyles. The work provides target-based insights for treating different types of cancers and presents research on evolutionary epigenetics, introducing ‘Medical Epi- Anthropology’ and ‘Cancer Epi-Anthropology’. Translating multi-disciplinary research into therapeutic design is at the core of this book. Readers may explore how cancer management involves unmasking the involved networks and the interactive status of different genes to achieve the appropriate methylome based therapy. Early chapters explore fundamental aspects and brain tumours, whilst later chapters investigate breast cancer and various other cancers, and the final chapter presents an evolutionary insight in cancer epigenetics, considering that the epigene is beyond DNA methylation, RNA interference and histone modification in cancer development. This book will be of interest to researchers in different medical and scientific fields, including clinical management (diagnosis, prognosis, prediction, prevention, and guidelines), genetic education, nutrition and nutrigenomics, industrial chemistry, and drug innovation. Because of the unique bridging between science and medicine this book will also be useful as an educational and translational research package.

Endocrinology  Adult and Pediatric E Book Book

Endocrinology Adult and Pediatric E Book


  • Author : J. Larry Jameson
  • Publisher : Elsevier Health Sciences
  • Release Date : 2015-02-25
  • Genre: Medical
  • Pages : 2700
  • ISBN 10 : 9780323321952

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Endocrinology Adult and Pediatric E Book Book Description :

Considered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Consult this title on your favorite e-reader.

Neurobiology of Motor Control Book

Neurobiology of Motor Control


  • Author : Scott L. Hooper
  • Publisher : John Wiley & Sons
  • Release Date : 2017-06-21
  • Genre: Medical
  • Pages : 512
  • ISBN 10 : 9781118873625

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Neurobiology of Motor Control Book Description :

A multi-disciplinary look at the current state of knowledge regarding motor control and movement—from molecular biology to robotics The last two decades have seen a dramatic increase in the number of sophisticated tools and methodologies for exploring motor control and movement. Multi-unit recordings, molecular neurogenetics, computer simulation, and new scientific approaches for studying how muscles and body anatomy transform motor neuron activity into movement have helped revolutionize the field. Neurobiology of Motor Control brings together contributions from an interdisciplinary group of experts to provide a review of the current state of knowledge about the initiation and execution of movement, as well as the latest methods and tools for investigating them. The book ranges from the findings of basic scientists studying model organisms such as mollusks and Drosophila, to biomedical researchers investigating vertebrate motor production to neuroengineers working to develop robotic and smart prostheses technologies. Following foundational chapters on current molecular biological techniques, neuronal ensemble recording, and computer simulation, it explores a broad range of related topics, including the evolution of motor systems, directed targeted movements, plasticity and learning, and robotics. Explores motor control and movement in a wide variety of organisms, from simple invertebrates to human beings Offers concise summaries of motor control systems across a variety of animals and movement types Explores an array of tools and methodologies, including electrophysiological techniques, neurogenic and molecular techniques, large ensemble recordings, and computational methods Considers unresolved questions and how current scientific advances may be used to solve them going forward Written specifically to encourage interdisciplinary understanding and collaboration, and offering the most wide-ranging, timely, and comprehensive look at the science of motor control and

Bread Making Book

Bread Making


  • Author : Stanley P Cauvain
  • Publisher : CRC Press
  • Release Date : 2003-09-17
  • Genre: Technology & Engineering
  • Pages : 500
  • ISBN 10 : 0849317622

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Bread Making Book Description :

Edited by one of the world's leading authorities in the field, Bread Making: Improving Quality reviews key recent research on the ingredients determining bread characteristics. The text discusses what this information means for improved process control and a better, more consistent product. After an introductory review, Part 1 discusses such concepts as the structure and quality of wheat and flour, and methods for measuring quality. Part 2 covers dough formation and its impact on bread's structure and properties. This includes such concepts as foam formation and bread aeration, key ingredients, improving taste and nutritional properties, and the prevention of moulds and mycotoxin contamination.

On Human Nature Book

On Human Nature


  • Author : Michel Tibayrenc
  • Publisher : Academic Press
  • Release Date : 2016-09-12
  • Genre: Science
  • Pages : 814
  • ISBN 10 : 9780127999159

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On Human Nature Book Description :

On Human Nature: Biology, Psychology, Ethics, Politics, and Religion covers the present state of knowledge on human diversity and its adaptative significance through a broad and eclectic selection of representative chapters. This transdisciplinary work brings together specialists from various fields who rarely interact, including geneticists, evolutionists, physicians, ethologists, psychoanalysts, anthropologists, sociologists, theologians, historians, linguists, and philosophers. Genomic diversity is covered in several chapters dealing with biology, including the differences in men and apes and the genetic diversity of mankind. Top specialists, known for their open mind and broad knowledge have been carefully selected to cover each topic. The book is therefore at the crossroads between biology and human sciences, going beyond classical science in the Popperian sense. The book is accessible not only to specialists, but also to students, professors, and the educated public. Glossaries of specialized terms and general public references help nonspecialists understand complex notions, with contributions avoiding technical jargon. Provides greater understanding of diversity and population structure and history, with crucial foundational knowledge needed to conduct research in a variety of fields, such as genetics and disease Includes three robust sections on biological, psychological, and ethical aspects, with cross-fertilization and reciprocal references between the three sections Contains contributions by leading experts in their respective fields working under the guidance of internationally recognized and highly respected editors

Evolutionary Biology from Concept to Application Book

Evolutionary Biology from Concept to Application


  • Author : Pierre Pontarotti
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-06-20
  • Genre: Science
  • Pages : 220
  • ISBN 10 : 9783540789932

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Evolutionary Biology from Concept to Application Book Description :

Every biological system is the outcome of its evolution; therefore, the deciphering of its evolutionary history is of tremendous importance to understand the biology of a system. Since 1997 scientists of different disciplines have held an annual "Evolutionary Biology Meeting" at Marseille (France) in order to discuss their research developments, exchange ideas and start collaborations. Consisting of the most representative talks of the 11th meeting, this book provides an up-to-date overview of evolutionary concepts and how these concepts can be applied to a better understanding of various biological aspects. It is divided into the following four parts: Modelization of Evolution - Concepts in Evolutionary Biology - Knowledge - Applied Evolutionary Biology. This book is an invaluable source of information not only for evolutionary biologists, but also for biologists in general.

Evolution of the Protein Synthesis Machinery and Its Regulation Book

Evolution of the Protein Synthesis Machinery and Its Regulation


  • Author : Greco Hernández
  • Publisher : Springer
  • Release Date : 2016-08-10
  • Genre: Science
  • Pages : 564
  • ISBN 10 : 9783319394688

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Evolution of the Protein Synthesis Machinery and Its Regulation Book Description :

The “omics” era has given a new perspective to the findings on the origin and evolution of the process of translation. This book provides insight into the evolution of the translation process and machinery from a modern perspective. Written by leading experts in molecular biology, this text looks into the origins and evolution of the protein synthetic machinery.

Evolution of Nervous Systems Book

Evolution of Nervous Systems


  • Author :
  • Publisher : Academic Press
  • Release Date : 2016-11-23
  • Genre: Medical
  • Pages : 2007
  • ISBN 10 : 9780128040966

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Evolution of Nervous Systems Book Description :

Evolution of Nervous Systems, Second Edition is a unique, major reference which offers the gold standard for those interested both in evolution and nervous systems. All biology only makes sense when seen in the light of evolution, and this is especially true for the nervous system. All animals have nervous systems that mediate their behaviors, many of them species specific, yet these nervous systems all evolved from the simple nervous system of a common ancestor. To understand these nervous systems, we need to know how they vary and how this variation emerged in evolution. In the first edition of this important reference work, over 100 distinguished neuroscientists assembled the current state-of-the-art knowledge on how nervous systems have evolved throughout the animal kingdom. This second edition remains rich in detail and broad in scope, outlining the changes in brain and nervous system organization that occurred from the first invertebrates and vertebrates, to present day fishes, reptiles, birds, mammals, and especially primates, including humans. The book also includes wholly new content, fully updating the chapters in the previous edition and offering brand new content on current developments in the field. Each of the volumes has been carefully restructured to offer expanded coverage of non-mammalian taxa, mammals, primates, and the human nervous system. The basic principles of brain evolution are discussed, as are mechanisms of change. The reader can select from chapters on highly specific topics or those that provide an overview of current thinking and approaches, making this an indispensable work for students and researchers alike. Presents a broad range of topics, ranging from genetic control of development in invertebrates, to human cognition, offering a one-stop resource for the evolution of nervous systems throughout the animal kingdom Incorporates the expertise of over 100 outstanding investigators who provide their conclusions in the context of the la

Literature  History  Choice Book

Literature History Choice


  • Author : Roman Katsman
  • Publisher : Cambridge Scholars Publishing
  • Release Date : 2013-11-01
  • Genre: Literary Criticism
  • Pages : 335
  • ISBN 10 : 9781443853842

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Literature History Choice Book Description :

Starting with a discussion on the elements of the genre of alternative (counterfactual) history and on its place between the poles of historical determinism and relativism, this book develops a literary theory of the historical alternativeness principle and applies it to the reading of The City with All That is Therein (Ir u-mloa) – one of the most important and less-studied books of the greatest Israeli writer, Nobel Prize winner S.Y. Agnon (1887-1970). The investigation reveals that this principle is by no means inherent solely in modernism and postmodernism, but lies at the very basis of the reading process, particularly at the levels of plot and character origination, and historical and historiographical conceptions that underlie the author’s imagination. The book is intended for all who are interested in modern literature and theory.

Plant Genomes Book

Plant Genomes


  • Author : Jean-Nicolas Volff
  • Publisher : Karger Medical and Scientific Publishers
  • Release Date : 2008-01-01
  • Genre: Medical
  • Pages : 145
  • ISBN 10 : 9783805584913

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Plant Genomes Book Description :

Recent major advances in the field of comparative genomics and cytogenomics of plants, particularly associated with the completion of ambitious genome projects, have uncovered astonishing facets of the architecture and evolutionary history of plant genomes. The aim of this book was to review these recent developments as well as their implications in our understanding of the mechanisms which drive plant diversity. New insights into the evolution of gene functions, gene families and genome size are presented, with particular emphasis on the evolutionary impact of polyploidization and transposable elements. Knowledge on the structure and evolution of plant sex chromosomes, centromeres and microRNAs is reviewed and updated. Taken together, the contributions by internationally recognized experts present a panoramic overview of the structural features and evolutionary dynamics of plant genomes.This volume of Genome Dynamics will provide researchers, teachers and students in the fields of biology and agronomy with a valuable source of current knowledge on plant genomes.

The Logic of Chance Book

The Logic of Chance


  • Author : Eugene V. Koonin
  • Publisher : FT Press
  • Release Date : 2011-06-23
  • Genre: Science
  • Pages : 528
  • ISBN 10 : 013262317X

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The Logic of Chance Book Description :

The Logic of Chance offers a reappraisal and a new synthesis of theories, concepts, and hypotheses on the key aspects of the evolution of life on earth in light of comparative genomics and systems biology. The author presents many specific examples from systems and comparative genomic analysis to begin to build a new, much more detailed, complex, and realistic picture of evolution. The book examines a broad range of topics in evolutionary biology including the inadequacy of natural selection and adaptation as the only or even the main mode of evolution; the key role of horizontal gene transfer in evolution and the consequent overhaul of the Tree of Life concept; the central, underappreciated evolutionary importance of viruses; the origin of eukaryotes as a result of endosymbiosis; the concomitant origin of cells and viruses on the primordial earth; universal dependences between genomic and molecular-phenomic variables; and the evolving landscape of constraints that shape the evolution of genomes and molecular phenomes. "Koonin's account of viral and pre-eukaryotic evolution is undoubtedly up-to-date. His "mega views" of evolution (given what was said above) and his cosmological musings, on the other hand, are interesting reading." Summing Up: Recommended Reprinted with permission from CHOICE, copyright by the American Library Association.