From Melanocytes to Melanoma Book

From Melanocytes to Melanoma


  • Author : Vincent J. Hearing
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-11-05
  • Genre: Medical
  • Pages : 678
  • ISBN 10 : 9781592599943

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From Melanocytes to Melanoma Excerpt :

Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Pathology of Melanocytic Tumors E Book Book

Pathology of Melanocytic Tumors E Book


  • Author : Klaus J. Busam
  • Publisher : Elsevier Health Sciences
  • Release Date : 2018-07-30
  • Genre: Medical
  • Pages : 608
  • ISBN 10 : 9780323508681

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Pathology of Melanocytic Tumors E Book Excerpt :

Constituting a large percentage of everyday diagnostic practice, melanocytic pathology is a complex and challenging area with many difficult-to-diagnose lesions. This highly illustrated reference, written by three of the world’s leading dermatopathologists, provides authoritative guidance in the accurate diagnosis of even the most challenging pigmented skin tumors, helping you avoid pitfalls and recognize mimics. Covers nearly every variant of melanocytic tumors you’re likely to see. Emphasizes how to arrive at an efficient, accurate diagnosis, and includes dermoscopic findings for optimal diagnostic precision. Discusses modern analytic techniques (cytogenetics, molecular studies) and how to use them for diagnosis. Includes numerous case examples to illustrate the differential diagnoses and work-up; how to use ancillary techniques, along with their pros, cons, and limitations; and clinical follow-up. Presents the knowledge and experience of Klaus Busam, Pedram Gerami, and Richard Scolyer, – three dermatopathologists who are globally renowned for their expertise in melanoma pathology and analysis of melanocytic tumors by modern ancillary diagnostic techniques.

Histological Diagnosis of Nevi and Melanoma Book
Score: 5
From 1 Ratings

Histological Diagnosis of Nevi and Melanoma


  • Author : Guido Massi
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-09-16
  • Genre: Medical
  • Pages : 752
  • ISBN 10 : 9783642373114

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Histological Diagnosis of Nevi and Melanoma Excerpt :

The interpretation of melanocytic tumors represents probably the most difficult task in the field of dermatopathology. The second edition of this text and atlas depicts a broad range of the most important and most challenging melanocytic lesions. Each individual case is illustrated with at least three high-quality color photographs and is commented on at length, highlighting the diagnostic clues. The goal of the authors is to assist the ordinary pathologist in making a precise workable diagnosis in their daily practice. They achieve this by providing simple criteria that will serve as a sound basis for an unequivocal diagnosis of either a benign or a malignant melanocytic neoplasm. The reader will find Histological Diagnosis of Nevi and Melanoma to be an invaluable guide to correct diagnosis even in difficult or rare cases.

Pathology of Melanocytic Nevi and Malignant Melanoma Book

Pathology of Melanocytic Nevi and Malignant Melanoma


  • Author : Michael Piepkorn
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-19
  • Genre: Medical
  • Pages : 406
  • ISBN 10 : 9780387216195

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Pathology of Melanocytic Nevi and Malignant Melanoma Excerpt :

Highly acclaimed and considered the leading reference in the field, Pathology of Melanocytic Nevi and Malignant Melanoma has now been fully revised and updated to accomodate rapid advances in the field of melanoma pathology. Drs. Michael Piepkorn and Klaus Busam have now joined Dr. Barnhill, world-renowned expert in dermatology and pathology, to expand the text with new sections on the genetics and cytogenetics of melanoma, sentinal lymph node biopsy, the new AJCC TNM staging system for melanoma, the mechanisms of melanoma metastasis. The successful focus and format of the first edition have been preserved. Each lesion and diagnosis is clearly illustrated, now with more than 340 new, digitally enhanced full-color photomicrographs and over 125 tables. A corresponding precis, or concise description of the clinical features, histopathology, differential diagnosis, and outstanding characteristics of each lesion provides readers with a quick yet comprehensive overview of each topic covered. With the inclusion of recent advances in cancer research and new techniques, the second edition of Pathology of Melanocytic Nevi and Malignant Melanoma is the essential reference for every practicing dermatopathologist, pathologist, dermatologist, and cancer research scientist today.

Melanoma Book

Melanoma


  • Author : Mandi Murph
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-04-01
  • Genre: Medical
  • Pages : 412
  • ISBN 10 : 9789535120360

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Melanoma Excerpt :

Melanoma - Current Clinical Management and Future Therapeutics serves as an advanced course in melanoma or an addendum to further polish expertise. Sections of the book include a thorough introduction on epidemiology and disease, the current surgical management of melanoma and lymph node dissection, immunotherapy along with drug toxicities and emerging research topics, like RAGE and autotaxin, that have potential therapeutic applications. The chapters in this book explore the most common subtype of melanoma, cutaneous disease, as well as a rare form, acral lentiginous melanoma and even canine tumors. Experts from around the globe contributed chapters, most of which have visual illustrations to depict aspects of disease management and therapy, allowing readers to grasp the advanced concepts presented.

Abeloff s Clinical Oncology E Book Book

Abeloff s Clinical Oncology E Book


  • Author : Martin D. Abeloff
  • Publisher : Elsevier Health Sciences
  • Release Date : 2008-06-30
  • Genre: Medical
  • Pages : 2592
  • ISBN 10 : 9781437720563

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Abeloff s Clinical Oncology E Book Excerpt :

Carrying on the tradition established by its founding editor, the late Dr. Martin Abeloff, the 4th Edition of this respected reference synthesizes all of the latest oncology knowledge in one practical, clinically focused, easy-to-use volume. It incorporates basic science, pathology, diagnosis, management, outcomes, rehabilitation, and prevention – all in one convenient resource – equipping you to overcome your toughest clinical challenges. What's more, you can access the complete contents of this Expert Consult title online, and tap into its unparalleled guidance wherever and whenever you need it most! Equips you to select the most appropriate tests and imaging studies for diagnosing and staging each type of cancer, and manage your patients most effectively using all of the latest techniques and approaches. Explores all of the latest scientific discoveries' implications for cancer diagnosis and management. Employs a multidisciplinary approach - with contributions from pathologists, radiation oncologists, medical oncologists, and surgical oncologists - for well-rounded perspectives on the problems you face. Offers a user-friendly layout with a consistent chapter format • summary boxes • a full-color design • and more than 1,445 illustrations (1,200 in full color), to make reference easy and efficient. Offers access to the book's complete contents online – fully searchable – from anyplace with an Internet connection. Presents discussions on cutting-edge new topics including nanotechnology, functional imaging, signal transduction inhibitors, hormone modulators, complications of transplantation, and much more. Includes an expanded color art program that highlights key points, illustrates relevant science and clinical problems, and enhances your understanding of complex concepts.

Cutaneous Melanoma Book

Cutaneous Melanoma


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2022-05-24
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : OCLC:1125727614

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Cutaneous Melanoma Excerpt :

From Melanocytes to Melanoma Book

From Melanocytes to Melanoma


  • Author : Vincent J. Hearing
  • Publisher : Humana
  • Release Date : 2005-12-15
  • Genre: Medical
  • Pages : 678
  • ISBN 10 : 1588294595

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From Melanocytes to Melanoma Excerpt :

Leading researchers and clinicians join forces to explain how malignant melanoma develops from its benign precursor cell type. The authors focus on the molecular mechanisms involved in melanogenesis, in the malignant transformation of melanocytes, and in the further progression of primary melanomas into invasive and metastatic melanomas. They also review recent advances in our understanding of the basic biology of melanocytes and the development, migration, and differentiation of melanoblasts into melanocytes. The book provides an up-to-date understanding of the progressive mechanisms of oncological development in malignant melanoma, a likely model of malignant progress for other types of cancer, and the ongoing development of novel therapeutics.

Recent Advances in the Biology  Therapy and Management of Melanoma Book

Recent Advances in the Biology Therapy and Management of Melanoma


  • Author : Lester M. Davids
  • Publisher : Unknown
  • Release Date : 2013
  • Genre: Uncategoriezed
  • Pages : 386
  • ISBN 10 : 9535170864

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Recent Advances in the Biology Therapy and Management of Melanoma Excerpt :

The book Recent Advances in the Biology, Therapy and Management of Melanoma brings up-to-date information regarding a number of aspects which culminate in illuminating potential targets in the fight against melanoma. This book is intended to be a reference book for both the scientific and clinical communities and brings complicated subject matter together in an easy, readable way. Undoubtedly fundamental scientific understanding has to then be translated to the clinic in order for us to make significant strides in eradicating melanoma. It is hoped that scientists, clinicians, students and residents find this book useful in their studies on melanoma and that it not only expands their perspectives and views on the field, but challenges them to forge ahead towards discovering the ultimate cure.

Pathology of Malignant Melanoma Book

Pathology of Malignant Melanoma


  • Author : A. Bernard Ackerman
  • Publisher : Unknown
  • Release Date : 1981
  • Genre: Melanoma
  • Pages : 393
  • ISBN 10 : UOM:39015000892474

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Pathology of Malignant Melanoma Excerpt :

Global Media Ethics is the first comprehensive cross-cultural exploration of the conceptual and practical issues facing media ethics in a global world. A team of leading journalism experts investigate the impact of major global trends on responsible journalism. The first full-length, truly global textbook on media ethics; Explores how current global changes in media promote and inhibit responsible journalism; Includes relevant and timely ethical discussions based on major trends in journalism and global media; Questions existing frameworks in media ethics in light of the impact of global media; Contributors are leading experts in global journalism and communication

Nevogenesis Book

Nevogenesis


  • Author : Ashfaq A. Marghoob
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-10-13
  • Genre: Medical
  • Pages : 160
  • ISBN 10 : 9783642283970

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Nevogenesis Excerpt :

The “Abtropfung” theory that nevi develop through the migration of nevus cells from the epidermis to the dermis prevailed for almost a century until the “Hochsteigerung” theory postulated the reverse pattern of migration. Most recently, however, new insights gained from epidemiology, cross-sectional and longitudinal studies of nevi, dermoscopy and confocal microscopy, and cellular and molecular studies have brought into question both of these theories. This book provides a comprehensive guide to current knowledge about nevogenesis by presenting these latest advances and in addition discusses issues yet to be resolved. It will assist practicing physicians in effectively managing patients with a variety of nevi and will also be of great value to researchers in the field. Importantly, since nevi are associated with an increased risk of melanoma, understanding nevogenesis may help to unravel some of the mysteries of melanomagenesis.

Melanoma of the Head and Neck Book

Melanoma of the Head and Neck


  • Author : John Joseph Conley
  • Publisher : Thieme Medical Pub
  • Release Date : 1990
  • Genre: Medical
  • Pages : 243
  • ISBN 10 : UOM:39015018920143

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Melanoma of the Head and Neck Excerpt :

A personal review by an active clinician of a very large group of cases of melanoma of the head and neck, extending over a 55-year period. Emphasizes probable clinical behavior and the rationale for treatment, with the hope of gaining the best prognosis with the optimal quality of life. A special feature is the inclusion of a succinct section of nevi and melanoma as interpreted by a dermatopathologist, A. Bernard Ackerman. The illustrations are exceptional throughout. Annotation copyrighted by Book News, Inc., Portland, OR

WHO Classification of Skin Tumours Book

WHO Classification of Skin Tumours


  • Author : D. E. Elder
  • Publisher : IARC Who Classification of Tum
  • Release Date : 2018-09-21
  • Genre: Medical
  • Pages : 500
  • ISBN 10 : 928322440X

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WHO Classification of Skin Tumours Excerpt :

The WHO Classification of Skin Tumours is the 11th volume in the 4th edition of the WHO series on the classification of human tumours. The series (also known as the Blue Books) has long been regarded by pathologists as the gold standard for the diagnosis of tumours, and it is an indispensable guide for the design of evaluations, clinical trials, and studies involving cancer. These authoritative and concise reference books provide an international standard for anyone involved in cancer research or the care of cancer patients. Diagnostic criteria, pathological features, and genetic and other associated molecular alterations are described in a disease-oriented manner. This volume updates the existing ICD-O codes and provides new codes for use in epidemiology and cancer registration. It also provides information on clinical features, pathology, genetics, prognosis, and protective factors for each of the tumour types covered. The editors expect that this volume will be of particular interest to pathologists, oncologists, and dermatologists who manage or research skin tumours. Sections are included on all recognized neoplasms (and their variants) of the skin and its adnexae. Since the previous edition, there have been particularly substantial changes to the classification of melanoma, based on the latest information from genetic and molecular studies.

Melanoma Development Book

Melanoma Development


  • Author : Anja K. Bosserhoff
  • Publisher : Springer
  • Release Date : 2017-01-20
  • Genre: Medical
  • Pages : 447
  • ISBN 10 : 9783319413198

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Melanoma Development Excerpt :

This book focuses on malignant melanoma, discussing the current state of scientific knowledge and providing insights into the underlying basic mechanisms, the molecular changes, genetics and genomics. Human Melanoma is a dangerous type of skin cancer affecting an increasing population, and a better understanding of its development will help in finding sophisticated targeted therapies. The second revised edition features the latest research findings and offers updates on the latest advances and potential novel melanoma therapies. It is a valuable resource for researchers and clinicians working in the fields of melanoma, cancer research and therapy as well as dermatology.

Human Skin Cancers Book

Human Skin Cancers


  • Author : Miroslav Blumenberg
  • Publisher : BoD – Books on Demand
  • Release Date : 2018-05-02
  • Genre: Medical
  • Pages : 212
  • ISBN 10 : 9781789230949

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Human Skin Cancers Excerpt :

Human skin cancers, the most common type of tumors, represent a significant health burden. The deadliest is unquestionably melanoma. Half of melanomas have an activating mutation in the BRAF gene, prompting development of novel drugs, vemurafenib and dabrafenib, specifically targeting mutated BRAF. Trametinib and cobimetinib, which block MEK, a BRAF effector protein, have been used in combination with BRAF inhibitors. A promising new melanoma treatment is immunotherapy, approach that boosts patient's own immune system to attack cancer. Pembrolizumab and nivolumab inhibit PD-1, whereas Ipilimumab targets CTLA-4, another immunity check point, to boost the immune response. Here we focus on pathways, mechanisms, targets and treatments of human skin cancers, with particular emphasis on the new developments in the research on melanomas.