Making Sense of Genes Book

Making Sense of Genes


  • Author : Kostas Kampourakis
  • Publisher : Cambridge University Press
  • Release Date : 2017-03-30
  • Genre: Science
  • Pages : 314
  • ISBN 10 : 9781107567498

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Making Sense of Genes Excerpt :

What are genes? What do genes do? These seemingly simple questions are in fact challenging to answer accurately. As a result, there are widespread misunderstandings and over-simplistic answers, which lead to common conceptions widely portrayed in the media, such as the existence of a gene 'for' a particular characteristic or disease. In reality, the DNA we inherit interacts continuously with the environment and functions differently as we age. What our parents hand down to us is just the beginning of our life story. This comprehensive book analyses and explains the gene concept, combining philosophical, historical, psychological and educational perspectives with current research in genetics and genomics. It summarises what we currently know and do not know about genes and the potential impact of genetics on all our lives. Making Sense of Genes is an accessible but rigorous introduction to contemporary genetics concepts for non-experts, undergraduate students, teachers and healthcare professionals.

The Epigenetics Revolution Book
Score: 3
From 4 Ratings

The Epigenetics Revolution


  • Author : Nessa Carey
  • Publisher : Columbia University Press
  • Release Date : 2012-03-06
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9780231530712

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The Epigenetics Revolution Excerpt :

Epigenetics can potentially revolutionize our understanding of the structure and behavior of biological life on Earth. It explains why mapping an organism's genetic code is not enough to determine how it develops or acts and shows how nurture combines with nature to engineer biological diversity. Surveying the twenty-year history of the field while also highlighting its latest findings and innovations, this volume provides a readily understandable introduction to the foundations of epigenetics. Nessa Carey, a leading epigenetics researcher, connects the field's arguments to such diverse phenomena as how ants and queen bees control their colonies; why tortoiseshell cats are always female; why some plants need cold weather before they can flower; and how our bodies age and develop disease. Reaching beyond biology, epigenetics now informs work on drug addiction, the long-term effects of famine, and the physical and psychological consequences of childhood trauma. Carey concludes with a discussion of the future directions for this research and its ability to improve human health and well-being.

Frontiers in Human Genetics Book

Frontiers in Human Genetics


  • Author : Eric Yap
  • Publisher : World Scientific
  • Release Date : 2001
  • Genre: Science
  • Pages : 396
  • ISBN 10 : 9789810244583

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Frontiers in Human Genetics Excerpt :

With the completion of human genome sequencing, human genetics is poised for major developments in functional genomics, molecular diagnostics, pathogenesis of complex multifactorial diseases and gene-based therapy. This book was conceived from an international symposium on human genetics and gene therapy that was held in Singapore in 1999. It includes manuscripts of the work presented as well as articles written by a selection of young researchers in the Asia Pacific region who are actively involved in a diverse range of medical problems, including cancer, infections, hypertension and myopia. New technologies being developed in gene therapy, lab-on-chips and bioinformatics are reported. The book provides a snapshot of the diverse approaches and solutions being developed at the frontiers of human genetics. It will be useful to researchers and students in molecular genetics and the life sciences, professionals in the biotechnology and pharmaceutical industries, clinicians who are interested in molecular medicine, etc.

Chromosome Biology as a Key to Understand Disease Mechanisms  Genome Architecture and Evolution Book

Chromosome Biology as a Key to Understand Disease Mechanisms Genome Architecture and Evolution


  • Author : Anja Weise
  • Publisher : Frontiers Media SA
  • Release Date : 2021-04-16
  • Genre: Science
  • Pages : null
  • ISBN 10 : 9782889666812

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Chromosome Biology as a Key to Understand Disease Mechanisms Genome Architecture and Evolution Excerpt :

This topic has been realized, and is in collaboration with Dr. Constanze Pentzold, Post Doctoral Researcher at the Institute of Human Genetics, University Hospital Jena.

Frontiers in Human Genetics Book

Frontiers in Human Genetics


  • Author : E. Yap
  • Publisher : World Scientific
  • Release Date : 2001
  • Genre: Science
  • Pages : 396
  • ISBN 10 : 9812385231

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Frontiers in Human Genetics Excerpt :

With the completion of human genome sequencing, human genetics is poised for major developments in functional genomics, molecular diagnostics, pathogenesis of complex multifactorial diseases and gene-based therapy. This book includes manuscripts from an international symposium on human genetics and gene therapy as well as articles written by a selection of young researchers in the Asia Pacific region who are actively involved in a diverse range of medical problems, including cancers, infections, hypertension and myopia. New technologies being developed in gene therapy, lab-on-chips and bioinformatics are reported. The book provides a snapshot of the diverse approaches and solutions being developed at the frontiers of human genetics.

Scientific Frontiers in Developmental Toxicology and Risk Assessment Book

Scientific Frontiers in Developmental Toxicology and Risk Assessment


  • Author : National Research Council
  • Publisher : National Academies Press
  • Release Date : 2000-12-21
  • Genre: Nature
  • Pages : 354
  • ISBN 10 : 9780309070867

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Scientific Frontiers in Developmental Toxicology and Risk Assessment Excerpt :

Scientific Frontiers in Developmental Toxicology and Risk Assessment reviews advances made during the last 10-15 years in fields such as developmental biology, molecular biology, and genetics. It describes a novel approach for how these advances might be used in combination with existing methodologies to further the understanding of mechanisms of developmental toxicity, to improve the assessment of chemicals for their ability to cause developmental toxicity, and to improve risk assessment for developmental defects. For example, based on the recent advances, even the smallest, simplest laboratory animals such as the fruit fly, roundworm, and zebrafish might be able to serve as developmental toxicological models for human biological systems. Use of such organisms might allow for rapid and inexpensive testing of large numbers of chemicals for their potential to cause developmental toxicity; presently, there are little or no developmental toxicity data available for the majority of natural and manufactured chemicals in use. This new approach to developmental toxicology and risk assessment will require simultaneous research on several fronts by experts from multiple scientific disciplines, including developmental toxicologists, developmental biologists, geneticists, epidemiologists, and biostatisticians.

Frontiers in Human Genetics Book

Frontiers in Human Genetics


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2001
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : OCLC:1100854399

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Frontiers in Human Genetics Excerpt :

Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson s Disease Book

Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson s Disease


  • Author : Soraya Bardien
  • Publisher : Frontiers Media SA
  • Release Date : 2021-05-05
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9782889667451

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Celebrating the Diversity of Genetic Research to Dissect the Pathogenesis of Parkinson s Disease Excerpt :

We would like to acknowledge Prof Rejko Krueger, from University of Luxembourg, who acted as a coordinator contributing to the preparation of the proposal for this Research Topic as part of the GEoPD.

Genomics in Aquaculture to Better Understand Species Biology and Accelerate Genetic Progress Book

Genomics in Aquaculture to Better Understand Species Biology and Accelerate Genetic Progress


  • Author : José Manuel Yáñez
  • Publisher : Frontiers Media SA
  • Release Date : 2016-09-15
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 9782889199570

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Genomics in Aquaculture to Better Understand Species Biology and Accelerate Genetic Progress Excerpt :

From a global perspective aquaculture is an activity related to food production with large potential for growth. Considering a continuously growing population, the efficiency and sustainability of this activity will be crucial to meet the needs of protein for human consumption in the near future. However, for continuous enhancement of the culture of both fish and shellfish there are still challenges to overcome, mostly related to the biology of the cultured species and their interaction with (increasingly changing) environmental factors. Examples of these challenges include early sexual maturation, feed meal replacement, immune response to infectious diseases and parasites, and temperature and salinity tolerance. Moreover, it is estimated that less than 10% of the total aquaculture production in the world is based on populations genetically improved by means of artificial selection. Thus, there is considerable room for implementing breeding schemes aimed at improving productive traits having significant economic impact. By far the most economically relevant trait is growth rate, which can be efficiently improved by conventional genetic selection (i.e. based on breeding values of selection candidates). However, there are other important traits that cannot be measured directly on selection candidates, such as resistance against infectious and parasitic agents and carcass quality traits (e.g. fillet yield and meat color). However, these traits can be more efficiently improved using molecular tools to assist breeding programs by means of marker-assisted selection, using a few markers explaining a high proportion of the trait variation, or genomic selection, using thousands of markers to estimate genomic breeding values. The development and implementation of new technologies applied to molecular biology and genomics, such as next-generation sequencing methods and high-throughput genotyping platforms, are allowing the rapid increase of availability of genomic resources in

New Frontiers in Human Genetics Book

New Frontiers in Human Genetics


  • Author : Lesley Easton
  • Publisher : States Academic Press
  • Release Date : 2021-11-16
  • Genre: Science
  • Pages : 252
  • ISBN 10 : 1639893741

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New Frontiers in Human Genetics Excerpt :

Human genetics is concerned with the study of the inheritance of characteristics from parents to children. This inheritance in humans depends upon discrete units called factors or genes. Human genes refer to a set of nucleic acid sequences that are encoded as DNA in the twenty-three chromosome pairs. The field of human genetics attempts to understand the genetics of human life and the development of diseases and its effective treatment. The discipline overlaps with other fields such as cytogenetics, biochemical genetics, population genetics, genetic counseling, developmental genetics, genomics, etc. There has been rapid progress in this field and its applications are finding their way across multiple industries such as medicine and biotechnology. The book studies, analyzes and upholds the pillars of human genetics and its utmost significance in modern times. It contains some path-breaking studies in the field of human genetics. In this book, using case studies and examples, constant effort has been made to make the understanding of the difficult concepts of human genetics as easy and informative as possible, for the readers.

Pseudomonas Aeruginosa  Biology  Genetics  and Host pathogen Interactions Book

Pseudomonas Aeruginosa Biology Genetics and Host pathogen Interactions


  • Author : Dara W. Frank
  • Publisher : Frontiers E-books
  • Release Date : 2012-02-02
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 9782889190164

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Pseudomonas Aeruginosa Biology Genetics and Host pathogen Interactions Excerpt :

The opportunistic pathogen Pseudomonas aeruginosa offers a rich variety of biologically relevant topics to explore and serves as a model system to understand the interactions of Gram-negative bacteria with human hosts. The organism adapts readily to most environments. It has a large and variable genome with a great deal of metabolic potential. P. aeruginosa encodes a variety of regulatory systems to fine tune gene expression and integrate environmental signals. This organism can infect both plants and animals and produces a plethora of enzymes and factors that can overcome host defenses. Moreover, it has the ability to change between the states of a sedentary colonizer to an invasive and highly motile organism. Clinically, the bacterium is resistant to many antibiotics making it difficult to treat and impossible to eradicate from the lungs of patients with cystic fibrosis. Intrinsic antibiotic resistance combined with an armamentarium of tissue degradative enzymes makes it imperative to possess a comprehensive understanding of the biology, genetics and pathogenesis of this organism so that novel therapeutics based on virulence product neutralization can be designed and implemented. This Research Topics issue will be devoted to updating the current understanding of P. aeruginosa systems as they relate to its different lifestyles in different environments. The underlying theme is to provide broad overviews and to integrate protein structure-function and gene regulation as it relates to the biology of this bacterium.