Functionalised Cardiovascular Stents Book

Functionalised Cardiovascular Stents


  • Author : Gerard Wall
  • Publisher : Woodhead Publishing
  • Release Date : 2018-02-06
  • Genre: Medical
  • Pages : 368
  • ISBN 10 : 9780081004982

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Functionalised Cardiovascular Stents Excerpt :

Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used interventions to treat arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally, some cardiovascular stents have been associated with serious side-effects, such as thrombosis. This book describes the fundamentals of cardiovascular stents, technologies to functionalize their surfaces and the market status of these important implants. The chapters provide specific focus on the production and evolution of cardiovascular stents, providing essential knowledge for researchers on advances in the field and knowledge of how cardiovascular stents are currently being "functionalized" in order to improve their biocompatibility and minimize negative outcomes in vivo. Provides a specific focus on cardiovascular stents Includes a range of topics covering the fundamentals, surface modification and biofunctionalization Provides essential knowledge for researchers on advances in the field

Functionalised Cardiovascular Stents Book

Functionalised Cardiovascular Stents


  • Author : Gerard Wall
  • Publisher : Woodhead Publishing Limited
  • Release Date : 2017-10-01
  • Genre: Uncategoriezed
  • Pages : 630
  • ISBN 10 : 0081004966

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Functionalised Cardiovascular Stents Excerpt :

Cardiovascular disease is a major cause of mortality in the western world and about half of these deaths are caused by coronary artery disease. One of the most commonly used implants to treat these arterial blockages is to deploy an arterial stent to keep the vessel open. Traditionally cardiovascular stents have been associated with serious side-effects, such as thrombosis. Research is being developed to 'functionalise' cardiovascular stents in order to improve their biocompatibility and minimise side-effects. This book describes the fundamentals of cardiovascular stents, technologies to functionalise their surfaces and the market status of these important implants. Provides a specific focus on cardiovascular stents Includes a range of topics coverering the fundamentals, surface modification and biofunctionalisation Provides essential knowledge for researchers on advances in the field

Biomaterials and Devices for the Circulatory System Book

Biomaterials and Devices for the Circulatory System


  • Author : Terence Gourlay
  • Publisher : Elsevier
  • Release Date : 2010-10-28
  • Genre: Medical
  • Pages : 400
  • ISBN 10 : 9780857090553

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Biomaterials and Devices for the Circulatory System Excerpt :

Cardiovascular disease is one of the leading causes of death in the world today. Thanks to major advances in circulatory biomaterials and medical devices over the past few decades, many complications of this prevalent disease can be managed with great success for prolonged periods. Biomaterials and devices for the circulatory system reviews the latest developments in this important field and how they can be used to improve the success and safety in this industry. Part one discusses physiological responses to biomaterials with chapters on tissue response, blood interface and biocompatibility. Part two then reviews clinical applications including developments in valve technology, percutaneous valve replacement, bypass technologies and cardiovascular stents. Part three covers future developments in the field with topics such as nanomedicine, cardiac restoration therapy, biosensor technology in the treatment of cardiovascular disease and vascular tissue engineering. With its distinguished editors and international team of contributors Biomaterials and devices for the circulatory system is a vital reference for those concerned with bioengineering, medical devices and clinicians within this critical field. Reviews the latest developments in this important field and how they can be used to improve success and safety in the industry Both current clinical advances as well as future innovation are assessed taking a progressive view of the role of biomaterials in medical applications An examination of the physiological responses to biomaterials features tissue responses to implanted materials and strategies to improve the biocompatibility of medical devices

Coronary Artery Disease and The Evolution of Angioplasty Devices Book

Coronary Artery Disease and The Evolution of Angioplasty Devices


  • Author : Martin W. King
  • Publisher : Springer Nature
  • Release Date : 2020-05-18
  • Genre: Technology & Engineering
  • Pages : 66
  • ISBN 10 : 9783030424435

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Coronary Artery Disease and The Evolution of Angioplasty Devices Excerpt :

In this concise but authoritative book, the authors take the reader through the epidemiology, risk factors and the basic mechanism of coronary artery disease. In addition, they explain how coronary microvascular dysfunction can lead to angina, even after successful angioplasty following a heart attack. The methods for diagnosis and the options for treatment are explained, ending with a discussion of the evolution of coronary angioplasty from balloon catheters to novel, fully resorbable polymeric drug eluting stents. Enclosed is a list of currently available commercial devices, as well as a listing of experimental products under research and development, so that readers can appreciate the serious nature of this disease and have an understanding of how the medical device sector is attempting to address this major healthcare problem. Globally in 2010, ischemic heart disease was the cause of 13.3% of all deaths. In the US alone, the direct medical costs from coronary artery disease and stroke are currently estimated to be $126 billion per year, and are expected to rise to $309 billion by 2035.

The Chemistry of Inorganic Biomaterials Book

The Chemistry of Inorganic Biomaterials


  • Author : Christopher Spicer
  • Publisher : Royal Society of Chemistry
  • Release Date : 2021-08-18
  • Genre: Science
  • Pages : 323
  • ISBN 10 : 9781788017534

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The Chemistry of Inorganic Biomaterials Excerpt :

This book overviews the underlying chemistry behind the most common and cutting-edge inorganic materials in current use, or approaching use, in vivo.

Coatings for Biomedical Applications Book

Coatings for Biomedical Applications


  • Author : Mike Driver
  • Publisher : Elsevier
  • Release Date : 2012-02-22
  • Genre: Science
  • Pages : 376
  • ISBN 10 : 9780857093677

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Coatings for Biomedical Applications Excerpt :

The biomaterials sector is rapidly expanding and significant advances have been made in the technology of biomedical coatings and materials, which provide a means to improve the wear of joints, change the biological interaction between implant and host and combine the properties of various materials to improve device performance. Coatings for biomedical applications provides an extensive review of coating types and surface modifications for biomedical applications. The first part of the book explores a range of coating types and their biomedical applications. Chapters look at hydrophilic, mineral and pyrolytic carbon coatings in and ex vivo orthopaedic applications and finally at surface modification and preparation techniques. Part two presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices. With its clear structure and comprehensive review of research, Coatings for biomedical applications is a valuable resource to researchers, scientists and engineers in the biomedical industry. It will also benefit anyone studying or working within the biomedical sector, particularly those specialising in biomedical coatings. Provides an extensive review of coating types and surface modifications for biomedical applications Chapters look at hydrophilic coatings for biomedical applications in and ex vivo, mineral coatings for orthopaedic applications, pyrolytic carbon coating and other commonly-used biomedical coatings Presents case studies of orthopaedic and ophthalmic coatings, and biomedical applications including vascular stents, cardiopulomonary by-pass equipment and ventricular assist devices

Recent Advances in Mechanical Engineering Book

Recent Advances in Mechanical Engineering


  • Author : Anil Kumar
  • Publisher : Springer Nature
  • Release Date : 2021-05-25
  • Genre: Science
  • Pages : 1161
  • ISBN 10 : 9789811596780

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Recent Advances in Mechanical Engineering Excerpt :

This book presents the select proceedings of the second International Conference on Recent Advances in Mechanical Engineering (RAME 2020). The topics covered include aerodynamics and fluid mechanics, automation, automotive engineering, composites, ceramics and polymers processing, computational mechanics, failure and fracture mechanics, friction, tribology and surface engineering, heating and ventilation, air conditioning system, industrial engineering, IC engines, turbomachinery and alternative fuels, machinability and formability of materials, mechanisms and machines, metrology and computer-aided inspection, micro- and nano-mechanics, modelling, simulation and optimization, product design and development, rapid manufacturing technologies and prototyping, solid mechanics and structural mechanics, thermodynamics and heat transfer, traditional and non-traditional machining processes, vibration and acoustics. The book also discusses various energy-efficient renewable and non-renewable resources and technologies, strategies and technologies for sustainable development and energy & environmental interaction. The book is a valuable reference for beginners, researchers, and professionals interested in sustainable construction and allied fields.

8th European Medical and Biological Engineering Conference Book

8th European Medical and Biological Engineering Conference


  • Author : Tomaz Jarm
  • Publisher : Springer Nature
  • Release Date : 2020-11-29
  • Genre: Technology & Engineering
  • Pages : 1172
  • ISBN 10 : 9783030646103

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8th European Medical and Biological Engineering Conference Excerpt :

This book aims at informing on new trends, challenges and solutions, in the multidisciplinary field of biomedical engineering. It covers traditional biomedical engineering topics, as well as innovative applications such as artificial intelligence in health care, tissue engineering , neurotechnology and wearable devices. Further topics include mobile health and electroporation-based technologies, as well as new treatments in medicine. Gathering the proceedings of the 8th European Medical and Biological Engineering Conference (EMBEC 2020), held on November 29 - December 3, 2020, in Portorož, Slovenia, this book bridges fundamental and clinically-oriented research, emphasizing the role of education, translational research and commercialization of new ideas in biomedical engineering. It aims at inspiring and fostering communication and collaboration between engineers, physicists, biologists, physicians and other professionals dealing with cutting-edge themes in and advanced technologies serving the broad field of biomedical engineering.

Shape Memory Polymers Book

Shape Memory Polymers


  • Author : Jinlian Hu
  • Publisher : Smithers Rapra
  • Release Date : 2014-05-27
  • Genre: Science
  • Pages : 326
  • ISBN 10 : 9781909030336

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Shape Memory Polymers Excerpt :

Shape-memory polymers (SMP) are a unique branch of the smart materials family which are capable of changing shape on-demand upon exposure to external stimulus. The discovery of SMP made a significant breakthrough in the developments of novel smart materials for a variety of engineering applications, superseded the traditional materials, and also influenced the current methods of product designing. This book provides the latest advanced information of on-going research domains of SMP. This will certainly enlighten the reader to the achievements and tremendous potentials of SMP. The basic fundamentals of SMP, including shape-memory mechanisms and mechanics are described. This will aid reader to become more familiar with SMP and the basic concepts, thus guiding them in undergoing independent research in the SMP field. The book also provides the reader with associated challenges and existing application problems of SMP. This could assist the reader to focus more on these issues and further exploit their knowledge to look for innovative solutions. Future outlooks of SMP research are discussed as well. This book should prove to be extremely useful for academics, R&D managers, researcher scientists, engineers, and all others related to the SMP research.

Biotechnological Applications of Polyhydroxyalkanoates Book

Biotechnological Applications of Polyhydroxyalkanoates


  • Author : Vipin Chandra Kalia
  • Publisher : Springer
  • Release Date : 2019-01-24
  • Genre: Science
  • Pages : 420
  • ISBN 10 : 9789811337598

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Biotechnological Applications of Polyhydroxyalkanoates Excerpt :

This book presents the latest research on the uses of polyhydroxyalkanoates (PHA), introducing readers to these natural, biodegradable polyesters produced by microorganisms, their functions and applications. The individual chapters discuss the various potentials of these bioplastics, which offer an attractive alternative to non-biodegradable plastics. The book also describes the diverse medical and biomedical applications of PHAs, including their use as drug carriers, memory enhancers, and biocontrol agents, and examines their role in creating a more sustainable economy – which is the need of the hour.

Bioresorbable Scaffolds Book

Bioresorbable Scaffolds


  • Author : Yoshinobu Onuma
  • Publisher : CRC Press
  • Release Date : 2017-10-02
  • Genre: Medical
  • Pages : 533
  • ISBN 10 : 9781498779777

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Bioresorbable Scaffolds Excerpt :

This book focuses on the coronary bioresorbable scaffold, a new interventional treatment for coronary artery disease, differentiated from a permanent metallic stent. The book provides an overview of the technology including non-clinical studies and clinical evidences in order to help clinicians understand the appropriate application of the technology and the optimal techniques of implantation. It covers the basics of bioresorbable scaffolds; bench test results; preclinical studies; clinical evidences; and tips and tricks of implantation.

Plasma Processes and Polymers Book

Plasma Processes and Polymers


  • Author : Riccardo d'Agostino
  • Publisher : John Wiley & Sons
  • Release Date : 2006-03-06
  • Genre: Science
  • Pages : 545
  • ISBN 10 : 9783527605576

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Plasma Processes and Polymers Excerpt :

This volume compiles essential contributions to the most innovative fields of Plasma Processes and Polymers. High-quality contributions cover the fields of plasma deposition, plasma treatment of polymers and other organic compounds, plasma processes under partial vacuum and at atmospheric pressure, biomedical, textile, automotive, and optical applications as well as surface treatment of bulk materials, clusters, particles and powders. This unique collection of refereed papers is based on the best contributions presented at the 16th International Symposium on Plasma Chemistry in Taormina, Italy (ISPC-16, June 2003). A high class reference of relevance to a large audience in plasma community as well as in the area of its industrial applications.

Tissue Engineered Vascular Grafts Book

Tissue Engineered Vascular Grafts


  • Author : Beat Walpoth
  • Publisher : Springer
  • Release Date : 2020-10-11
  • Genre: Science
  • Pages : 575
  • ISBN 10 : 3030053350

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Tissue Engineered Vascular Grafts Excerpt :

Cardiovascular diseases are still the leading cause of death in developed countries. Revascularization procedures such as coronary artery and peripheral bypass grafts, as well as access surgery represent a 2$ billion market yearly for the US alone. Despite intense research over many decades, no clinically suitable, shelf-ready, synthetic, vascular, small-caliber graft exists. There is therefore still a quest for such a clinical vascular prosthesis for surgical revascularization procedures and access surgery. Many approaches have been tried and are currently under investigation with promising results. These range from acellular and cell-based, stable or bio-degradable, synthetic scaffolds to biological or decellularized grafts, not forgetting self-assembly technologies for in vitro or in vivo VTE. All these approaches can be further enhanced by functionalization, e.g. with growth factors and drug elution. This updatable book aims to cover all the relevant aspects of Vascular Tissue Engineering (VTE) and novel alternatives to develop vascular grafts for clinical applications. The chapters in this book cover different aspects of manufacturing scaffolds with various polymers, mechanical characteristics, degradation rates, decellularization techniques, cell sheet assembly, 3-D printing and autologous mandril-based VTE. All the necessary in vitro tests such as biocompatibility and thrombogenicity are reviewed. Pre-clinical assessment of in vivo experimental models include patency, compliance, intimal hyperplasia, inflammatory reaction, cellular ingrowth and remodeling. Finally, early clinical trials will be periodically updated regarding results, regulatory aspects and post-marketing quality assessment. Furthermore, the reader should get an insight into various approaches, technologies and methods to better understand the complexity of blood surface and cell interactions in VTE. Translational research has yielded early human applications clearly showing the enormous need

Nano Antimicrobials Book

Nano Antimicrobials


  • Author : Nicola Cioffi
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-02-26
  • Genre: Technology & Engineering
  • Pages : 563
  • ISBN 10 : 9783642244278

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Nano Antimicrobials Excerpt :

There is a high demand for antimicrobials for the treatment of new and emerging microbial diseases. In particular, microbes developing multidrug resistance have created a pressing need to search for a new generation of antimicrobial agents, which are effective, safe and can be used for the cure of multidrug-resistant microbial infections. Nano-antimicrobials offer effective solutions for these challenges; the details of these new technologies are presented here. The book includes chapters by an international team of experts. Chemical, physical, electrochemical, photochemical and mechanical methods of synthesis are covered. Moreover, biological synthesis using microbes, an option that is both eco-friendly and economically viable, is presented. The antimicrobial potential of different nanoparticles is also covered, bioactivity mechanisms are elaborated on, and several applications are reviewed in separate sections. Lastly, the toxicology of nano-antimicrobials is briefly assessed.