Functionalized Nanomaterials for the Management of Microbial Infection Book

Functionalized Nanomaterials for the Management of Microbial Infection


  • Author : Rabah Boukherroub
  • Publisher : Elsevier
  • Release Date : 2017-01-03
  • Genre: Uncategoriezed
  • Pages : 338
  • ISBN 10 : 032341625X

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Functionalized Nanomaterials for the Management of Microbial Infection Excerpt :

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. Provides the information users need to integrate antibacterial nanoparticles into future treatments Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection

Functionalized Nanomaterials for the Management of Microbial Infection Book

Functionalized Nanomaterials for the Management of Microbial Infection


  • Author : Rabah Boukherroub
  • Publisher : William Andrew
  • Release Date : 2016-12-14
  • Genre: Technology & Engineering
  • Pages : 338
  • ISBN 10 : 9780323417372

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Functionalized Nanomaterials for the Management of Microbial Infection Excerpt :

Functionalized Nanomaterials for the Management of Microbial Infection: A Strategy to Address Microbial Drug Resistance introduces the reader to the newly developing use of nanotechnology to combat microbial drug resistance. Excessive use of antibiotics and antimicrobial agents has produced an inexorable rise in antibiotic resistance in bacterial pathogens. The use of nanotechnology is currently the most promising strategy to overcome microbial drug resistance. This book shows how, due to their small size, nanoparticles can surmount existing drug resistance mechanisms, including decreased uptake and increased efflux of the drug from the microbial cell, biofilm formation, and intracellular bacteria. In particular, chapters cover the use of nanoparticles to raise intracellular antimicrobial levels, thus directly targeting sites of infection and packaging multiple antimicrobial agents onto a single nanoparticle. Provides the information users need to integrate antibacterial nanoparticles into future treatments Gives readers with backgrounds in nanotechnology, chemistry, and materials science an understanding of the main issues concerning microbial drug resistance and its challenges Includes real-life case studies that illustrates how functionalized nanomaterials are used to manage microbial infection

Nanotechnology in Diagnosis  Treatment and Prophylaxis of Infectious Diseases Book

Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases


  • Author : Mahendra Rai
  • Publisher : Academic Press
  • Release Date : 2015-05-23
  • Genre: Medical
  • Pages : 344
  • ISBN 10 : 9780128014714

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Nanotechnology in Diagnosis Treatment and Prophylaxis of Infectious Diseases Excerpt :

Nanotechnology in Diagnosis, Treatment and Prophylaxis of Infectious Diseases delivers comprehensive coverage of the application of nanotechnology to pressing problems in infectious disease. This text equips readers with cutting-edge knowledge of promising developments and future prospects in nanotechnology, paying special attention to microbes that are now resistant to conventional antibiotics, a concerning problem in modern medicine. Readers will find a thorough discussion of this new approach to infectious disease treatment, including the reasons nanotechnology presents a promising avenue for the diagnosis, treatment, and prophylaxis of infectious diseases. Provides a comprehensive overview of the use of nanotechnology in the treatment and diagnosis of infectious diseases Covers all common types of infective agents, including bacteria, viruses, fungi, and protozoa, along with their vectors, ticks, mosquitoes, flies, etc. Delivers commentary from an international researcher base, providing insights across differing economic statuses Includes a foundation of basic nanotechnological concepts to aid in designing new strategies to combat several pathogenic diseases and cancer Illustrates the high antimicrobial potential of nanoparticles, ultimately demonstrating how they are a promising alternative class that can be successfully used in fighting a myriad of infections

Nanostructures for Antimicrobial Therapy Book

Nanostructures for Antimicrobial Therapy


  • Author : Anton Ficai
  • Publisher : Elsevier
  • Release Date : 2017-05-29
  • Genre: Medical
  • Pages : 722
  • ISBN 10 : 9780323461511

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Nanostructures for Antimicrobial Therapy Excerpt :

Nanostructures for Antimicrobial Therapy discusses the pros and cons of the use of nanostructured materials in the prevention and eradication of infections, highlighting the efficient microbicidal effect of nanoparticles against antibiotic-resistant pathogens and biofilms. Conventional antibiotics are becoming ineffective towards microorganisms due to their widespread and often inappropriate use. As a result, the development of antibiotic resistance in microorganisms is increasingly being reported. New approaches are needed to confront the rising issues related to infectious diseases. The merging of biomaterials, such as chitosan, carrageenan, gelatin, poly (lactic-co-glycolic acid) with nanotechnology provides a promising platform for antimicrobial therapy as it provides a controlled way to target cells and induce the desired response without the adverse effects common to many traditional treatments. Nanoparticles represent one of the most promising therapeutic treatments to the problem caused by infectious micro-organisms resistant to traditional therapies. This volume discusses this promise in detail, and also discusses what challenges the greater use of nanoparticles might pose to medical professionals. The unique physiochemical properties of nanoparticles, combined with their growth inhibitory capacity against microbes has led to the upsurge in the research on nanoparticles as antimicrobials. The importance of bactericidal nanobiomaterials study will likely increase as development of resistant strains of bacteria against most potent antibiotics continues. Shows how nanoantibiotics can be used to more effectively treat disease Discusses the advantages and issues of a variety of different nanoantibiotics, enabling medics to select which best meets their needs Provides a cogent summary of recent developments in this field, allowing readers to quickly familiarize themselves with this topic area

Principles and Applications of Antimicrobial Nanomaterials Book

Principles and Applications of Antimicrobial Nanomaterials


  • Author : Joseph L. Graves Jr
  • Publisher : Elsevier
  • Release Date : 2021-08-19
  • Genre: Technology & Engineering
  • Pages : 344
  • ISBN 10 : 9780128232637

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Principles and Applications of Antimicrobial Nanomaterials Excerpt :

Principles and Applications of Antimicrobial Nanomaterials introduces the reader to the microbial world, antimicrobial nanomaterials, how microbial evolution works, and how knowledge of these areas can facilitate the development of sustainable antimicrobials. Due to the widespread occurrence of multidrug-resistant microbes, there is an increasing interest in the use of novel nanostructured materials as antimicrobials. This book is designed to help researchers from fields such as materials science, nanoscience, and nanoengineering who are attempting to develop these antimicrobial materials. Provides crucial background in microbiology and microbial evolution to help researchers design experiments that can produce sustainable results Offers detailed coverage on the antimicrobial properties of different types of nanomaterials Discusses the major challenges of using nanomaterials for antimicrobial applications

Preclinical Evaluation of Antimicrobial Nanodrugs Book

Preclinical Evaluation of Antimicrobial Nanodrugs


  • Author : Juan Bueno
  • Publisher : Springer Nature
  • Release Date : 2020-05-08
  • Genre: Medical
  • Pages : 117
  • ISBN 10 : 9783030438555

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Preclinical Evaluation of Antimicrobial Nanodrugs Excerpt :

Translational medicine addresses the gap between research and the clinical application of new discoveries. To efficiently deliver new drugs to care centers, a preclinical evaluation, both in vitro and in vivo, is required to ensure that the most active and least toxic compounds are selected as well as to predict clinical outcome. Antimicrobial nanomedicines have been shown to have higher specificity in their therapeutic targets and the ability to serve as adjuvants, increasing the effectiveness of pre-existing immune compounds. The design and development of new standardized protocols for evaluating antimicrobial nanomedicines is needed for both the industry and clinical laboratory. These protocols must aim to evaluate laboratory activity and present models of pharmacokinetic-pharmacodynamic and toxicokinetic behavior that predict absorption and distribution. Likewise, these protocols must follow a theranostics approach, be able to detect promising formulations, diagnose the infectious disease, and determine the correct treatment to implement a personalized therapeutic behavior. Given the possibilities that nanotechnology offers, not updating to new screening platforms is inadequate as it prevents the correct application of discoveries, increasing the effect of the valley of death between innovations and their use. This book is structured to discuss the fundamentals taken into account for the design of robust, reproducible and automatable evaluation platforms. These vital platforms should enable the discovery of new medicines with which to face antimicrobial resistance (RAM), one of the great problems of our time.

Nanotechnology Applied To Pharmaceutical Technology Book

Nanotechnology Applied To Pharmaceutical Technology


  • Author : Mahendra Rai
  • Publisher : Springer
  • Release Date : 2017-11-21
  • Genre: Medical
  • Pages : 386
  • ISBN 10 : 9783319702995

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Nanotechnology Applied To Pharmaceutical Technology Excerpt :

Focusing on the application of nanotechnology in pharmaceutical technology the editors seek to integrate the two in order to obtain innovative products and solutions in pharmacology. Interdisciplinary in content it is of interest to those who are involved in the development of nanoproducts including nanotechnologists, microbiologists, biotechnologists pharmacologists and clinicians. Recent studies are presented that include the biosynthesis of nanoparticles focusing on antimicrobials; nanomaterial-based formulations that treat cancer, infections, skin disorders and wounds;nanomaterials in eye diseases and toxicity and safety issues. It demonstrates the crucial role this plays in tackling multi-drug resistant threats.

Hydrogels Based on Natural Polymers Book

Hydrogels Based on Natural Polymers


  • Author : Yu Chen
  • Publisher : Elsevier
  • Release Date : 2019-10-23
  • Genre: Technology & Engineering
  • Pages : 552
  • ISBN 10 : 9780128166185

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Hydrogels Based on Natural Polymers Excerpt :

Hydrogels Based on Natural Polymers presents the latest research on natural polymer-based hydrogels, covering fundamentals, preparation methods, synthetic pathways, advanced properties, major application areas, and novel characterization techniques. The advantages and disadvantages of each natural polymer-based hydrogel are also discussed, enabling preparation tactics for specific properties and applications. Sections cover fundamentals, development, characteristics, structures and properties. Additional chapters cover presentation methods and properties based on natural polymers, including physical and chemical properties, stimuli-responsive properties, self-healing properties, and biological properties. The final section presents major applications areas, including the biomedical field, agriculture, water treatments, and the food industry. This is a highly valuable resource for academic researchers, scientists and advanced students working with hydrogels and natural polymers, as well as across the fields of polymer science, polymer chemistry, plastics engineering, biopolymers and biomaterials. The detailed information will also be of great interest to scientists and R&D professionals, product designers, technicians and engineers across industries. Provides systematic coverage of all aspects of hydrogels based on natural polymers, including fundamentals, preparation methods, properties and characterization Offers a balanced assessment of the specific properties and possibilities offered by different natural polymer-based hydrogels, drawing on innovative research Examines cutting-edge applications across biomedicine, agriculture, water treatments, and the food industry

Nanostructured Photocatalysts Book

Nanostructured Photocatalysts


  • Author : Rabah Boukherroub
  • Publisher : Elsevier
  • Release Date : 2020-06-06
  • Genre: Technology & Engineering
  • Pages : 300
  • ISBN 10 : 9780128178379

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Nanostructured Photocatalysts Excerpt :

Nanostructured Photocatalysts: From Materials to Applications in Solar Fuels and Environmental Remediation addresses the different properties of nanomaterials-based heterogeneous photocatalysis. Heterogeneous nanostructured photocatalysis represents an interesting and viable technique to address issues of climate change and global energy supply. Sustainable hydrogen (H2) fuel production from water via semiconductor photocatalysis, driven by solar energy, is regarded as a viable and sustainable solution to address increasing energy and environmental issues. Similarly, photocatalytic reduction of CO2 with water for the production of hydrocarbons could also be a viable solution. Sections cover band gap tuning, high surface area, the short diffusion path of carriers, and more. Introduces the utilization of nanostructured materials in heterogeneous photocatalysis for hydrogen fuel production via water splitting Explains preparation techniques for different nanomaterials and hybrid nanocomposites, enabling improved sunlight absorption efficiency and enhanced charge separation Assesses the challenges that need to be addressed before this technology can be practically implemented, particularly of identifying cost-effective nanophotocatalysts

Advances in Biomaterials for Biomedical Applications Book

Advances in Biomaterials for Biomedical Applications


  • Author : Anuj Tripathi
  • Publisher : Springer
  • Release Date : 2017-01-24
  • Genre: Technology & Engineering
  • Pages : 545
  • ISBN 10 : 9789811033285

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Advances in Biomaterials for Biomedical Applications Excerpt :

This book highlights recent advances in the field of biomaterials design and the state of the art in biomaterials applications for biomedicine. Addressing key aspects of biomaterials, the book explores technological advances at multi-scale levels (macro, micro, and nano), which are used in applications related to cell and tissue regeneration. The book also discusses the future scope of bio-integrated systems. The contents are supplemented by illustrated examples, and schematics of molecular and cellular interactions with biomaterials/scaffolds are included to promote a better understanding of the complex biological mechanisms involved in material-to-biomolecule interactions. The book also covers factors that govern cell growth, differentiation, and regeneration in connection with the treatment and recovery of native biological systems. Tissue engineering, drug screening and delivery, and electrolyte complexes for biomedical applications are also covered in detail. This book offers a comprehensive reference guide for multi-disciplinary communities working in the area of biomaterials, and will benefit researchers and graduate students alike.

Antibacterial Agents Book

Antibacterial Agents


  • Author : Ranjith Kumavath
  • Publisher : BoD – Books on Demand
  • Release Date : 2017-05-31
  • Genre: Science
  • Pages : 140
  • ISBN 10 : 9789535131991

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Antibacterial Agents Excerpt :

New drugs are frequently entering into the market along with the existing drugs. The antibacterial agents can be discussed in five major classes, i.e. classification based on the type of action, source, spectrum of activity, chemical structure and function. Resistance of bacteria to antibiotics is an urgent problem of the humanity, which leads us to the lack of therapy for serious bacterial infections. Development of new antibiotics has almost ceased in the last decades - even when a new antibiotic is launched, very soon the resistance of bacteria appears. Industrial textiles exposed as awnings, screens, tents; upholstery used in large public areas such as hospitals, hotels and stations; fabrics for transports; protective clothing and personal protective equipment; bed sheets and blankets; textiles left wet between processing steps; intimate apparel, underwear, socks and sportswear, disinfection of air and water for white rooms, hospitals and operating theatres, food and pharma industries, water depuration, drinkable water supplying and air conditioning systems. Many clinicians recommend alternative approaches to using antimicrobial substances. Moreover, the majority of bioagents demonstrate on antibiotics for treatment of a wide range of diseases in human sectors. However, the misuse and mishandling of drugs lead to microbial, particularly bacterial, resistance as well as result in the difficulty of treating microbial diseases. Hence, the proposed book will give more precise information on novel antibacterial compound(s).

Antibiotic Materials in Healthcare Book

Antibiotic Materials in Healthcare


  • Author : Kokkarachedu Varaprasad
  • Publisher : Academic Press
  • Release Date : 2020-05-22
  • Genre: Science
  • Pages : 346
  • ISBN 10 : 9780128225363

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Antibiotic Materials in Healthcare Excerpt :

Antibiotic Materials in Healthcare provides significant information on antibiotic related issues, accurate solutions, and recent investigative information for health-related applications. In addition, the book addresses the design and development of antibiotics with advanced (physical, chemical and biological) properties, an analysis of materials, in vivo and in vitro applications, and their biomedical applications for healthcare. Provides information on all aspects of antibiotic related issues Offers a balanced synthesis of basic and clinical science for each individual case, presenting clinical courses and detailed microbiological information for each infection Describes the prevalence and incidence of global issues and current therapeutic approaches

Functional Nanomaterials for Regenerative Tissue Medicines Book

Functional Nanomaterials for Regenerative Tissue Medicines


  • Author : Mariappan Rajan
  • Publisher : CRC Press
  • Release Date : 2021-12-09
  • Genre: Technology & Engineering
  • Pages : 420
  • ISBN 10 : 9781000486940

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Functional Nanomaterials for Regenerative Tissue Medicines Excerpt :

This book covers nanomaterials in tissue engineering for regenerative therapies of heart, skin, eye, skeletal muscle, and the nervous system. The book emphasizes fundamental design concepts and emerging forms of nanomaterials in soft- and hard-tissue engineering. FEATURES Fills a gap in the literature related to the application of nanomaterials in hard- and soft-tissue regeneration, repair, and restructure Discusses a variety of applications, including cardiac, kidney, liver, bone, wound healing, artificial organs, and dental Presents advantages and limitations of various nanomaterials alongside future challenges Functional Nanomaterials for Regenerative Tissue Medicines is essential for academics and industry professionals working in tissue engineering, biomedicine, biopharmaceuticals, and nanotechnology. It is primarily intended for materials researchers (to develop the platforms related to tissue regeneration) as well as clinicians (to learn and apply nanomaterials in their practice) and industrial scientists (to develop commercial blood substitute products).

Antibiotic Drug Resistance Book

Antibiotic Drug Resistance


  • Author : José-Luis Capelo-Martínez
  • Publisher : John Wiley & Sons
  • Release Date : 2019-09-24
  • Genre: Medical
  • Pages : 730
  • ISBN 10 : 9781119282525

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Antibiotic Drug Resistance Excerpt :

This book presents a thorough and authoritative overview of the multifaceted field of antibiotic science – offering guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases. Provides readers with knowledge about the broad field of drug resistance Offers guidance to translate research into tools for prevention, diagnosis, and treatment of infectious diseases Links strategies to analyze microbes to the development of new drugs, socioeconomic impacts to therapeutic strategies, and public policies to antibiotic-resistance-prevention strategies