Gastrointestinal Tissue Book

Gastrointestinal Tissue

  • Author : Jordi Gracia-Sancho
  • Publisher : Academic Press
  • Release Date : 2017-05-10
  • Genre: Medical
  • Pages : 394
  • ISBN 10 : 9780128093009

Gastrointestinal Tissue Excerpt :

Gastrointestinal Tissue: Oxidative Stress and Dietary Antioxidants brings together leading experts from world renowned institutions, combining the basic mechanisms of gastrointestinal diseases with information regarding new and alternative treatments. The processes within the science of oxidative stress are described in concert with other processes, including apoptosis, cell signaling and receptor mediated responses, further recognizing that diseases are often multifactorial with oxidative stress as a component. By combining the critical molecular processes underlying free radical mediated pathologies and the role of dietary antioxidant molecules, a connection is made that helps advance therapies and the prevention of gastrointestinal pathological processes. This important reference is well designed with two complementary sections. Section One, Oxidative Stress and Gastroenterology, covers the basic processes of oxidative stress from molecular biology to whole organs, the gastrointestinal anatomy and sources of oxidative stress and free radicals and their products in gastrointestinal diseases. Section Two, Antioxidants and Gastroenterology covers antioxidants in foods, including plants and components. Covers the science of oxidative stress in gastrointestinal tissue and associated conditions and scenarios Provides information on optimal levels for human consumption of antioxidants, suggested requirements per day, recommended dietary allowances and curative/preventive effects of dietary antioxidants Presents an easy to reference guide with two complementary sections that discuss the pathophysiology of gastrointestinal diseases in relation to oxidative stress and antioxidant therapies

Regulation of Gastrointestinal Mucosal Growth Book

Regulation of Gastrointestinal Mucosal Growth

  • Author : Rao N. Jaladanki
  • Publisher : Biota Publishing
  • Release Date : 2016-11-30
  • Genre: Medical
  • Pages : 150
  • ISBN 10 : 9781615047352

Regulation of Gastrointestinal Mucosal Growth Excerpt :

The mammalian gastrointestinal mucosa is a rapidly self-renewing tissue in the body, and its homeostasis is preserved through the strict regulation of epithelial cell proliferation, growth arrest, and apoptosis. The control of the growth of gastrointestinal mucosa is unique and, compared with most other tissue in the body, complex. Mucosal growth is regulated by the same hormones that alter metabolism in other tissues, but the gastrointestinal mucosa also responds to host events triggered by the ingestion and presence of food within the digestive tract. These gut hormones and peptides regulate the growth of the exocrine pancreas, gallbladder epithelium, and the mucosa of the oxyntic gland region of the stomach and the small and large intestines. Luminal factors, including nutrients or other dietary factors, secretions, and microbes that occur within the lumen and distribute over a proximal-to-distal gradient, are also crucial for maintenance of normal gut mucosal regeneration and could explain the villous-height-crypt-depth gradient and variety of adaptation, since these factors are diluted, absorbed, and destroyed as they pass down the digestive tract. Recently, intestinal stem cells, cellular polyamines, and noncoding RNAs are shown to play an important role in the regulation of gastrointestinal mucosal growth under physiological and various pathological conditions. In this book, we highlight key issues and factors that control gastrointestinal mucosal growth and homeostasis, with special emphasis on the mechanisms through which epithelial renewal and apoptosis are regulated at the cellular and molecular levels.

Gastrointestinal Reflux Disease  New Insights for the Healthcare Professional  2013 Edition Book

Gastrointestinal Reflux Disease New Insights for the Healthcare Professional 2013 Edition

  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-07-22
  • Genre: Medical
  • Pages : 64
  • ISBN 10 : 9781481658904

Gastrointestinal Reflux Disease New Insights for the Healthcare Professional 2013 Edition Excerpt :

Gastrointestinal Reflux Disease: New Insights for the Healthcare Professional: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Additional Research in a concise format. The editors have built Gastrointestinal Reflux Disease: New Insights for the Healthcare Professional: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Additional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Gastrointestinal Reflux Disease: New Insights for the Healthcare Professional: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at

Biomechanics of the Gastrointestinal Tract Book

Biomechanics of the Gastrointestinal Tract

  • Author : Hans Gregersen
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-04-18
  • Genre: Medical
  • Pages : 268
  • ISBN 10 : 9781447137429

Biomechanics of the Gastrointestinal Tract Excerpt :

Biomechanics of the Gastrointestinal Tract is an up-to-date book for researchers on the study of the mechanical properties and the motor system of the gastrointestinal tract. A well-illustrated book, it provides a comprehensive overview to relevant tissue geometry, morphology and biomechanical theory. Separate chapters cover smooth muscle and nerve function including the application to animal and human studies of motility, symptoms and pain, determination of the true resting state, history-dependent properties, and tissue remodelling in disease. Several methods and diagnostic applications such as determination of in vivo length-tension diagrams and multimodal pain testing are completely new but will undoubtedly be used by many in the future. New non-invasive imaging techniques based on ultrasound, MR- and CT-scanning in combination with balloon distension are emerging as the techniques for future in vivo studies.

Tissue Engineering Book

Tissue Engineering

  • Author : John P. Fisher
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-12-31
  • Genre: Technology & Engineering
  • Pages : 464
  • ISBN 10 : 9780387341330

Tissue Engineering Excerpt :

This special issue of the Advances in Experimental Medicine and Biology presents much of the research described at the recent 2nd International Tissue Engineering Conference held in Crete in May 2005. The conference brought together over 150 researchers from around the world to examine the emerging and most advanced aspects of their particular field. The chapters reflect a diverse group of authors, including both clinicians and academicians.

Translational Regenerative Medicine Book

Translational Regenerative Medicine

  • Author : Anthony Atala
  • Publisher : Academic Press
  • Release Date : 2014-12-01
  • Genre: Science
  • Pages : 606
  • ISBN 10 : 9780124104570

Translational Regenerative Medicine Excerpt :

Translational Regenerative Medicine is a reference book that outlines the life cycle for effective implementation of discoveries in the dynamic field of regenerative medicine. By addressing science, technology, development, regulatory, manufacturing, intellectual property, investment, financial, and clinical aspects of the field, this work takes a holistic look at the translation of science and disseminates knowledge for practical use of regenerative medicine tools, therapeutics, and diagnostics. Incorporating contributions from leaders in the fields of translational science across academia, industry, and government, this book establishes a more fluid transition for rapid translation of research to enhance human health and well-being. Provides formulaic coverage of the landscape, process development, manufacturing, challenges, evaluation, and regulatory aspects of the most promising regenerative medicine clinical applications Covers clinical aspects of regenerative medicine related to skin, cartilage, tendons, ligaments, joints, bone, fat, muscle, vascular system, hematopoietic /immune system, peripheral nerve, central nervous system, endocrine system, ophthalmic system, auditory system, oral system, respiratory system, cardiac system, renal system, hepatic system, gastrointestinal system, genitourinary system Identifies effective, proven tools and metrics to identify and pursue clinical and commercial regenerative medicine

Immunopharmacology of the Gastrointestinal System Book

Immunopharmacology of the Gastrointestinal System

  • Author : John L. Wallace
  • Publisher : Academic Press
  • Release Date : 1993-03-01
  • Genre: Medical
  • Pages : 198
  • ISBN 10 : 9781483289335

Immunopharmacology of the Gastrointestinal System Excerpt :

Diseases of the digestive system have a higher morbidity rate than any other group of disorder. There is a growing body of evidence that the immune system participates in the pathogenesis of a wide range of these diseases, including peptic ulcer disease and the gastropathy induced by nonsteroidal anti-inflammatory drugs (NSAIDS). For these reasons, efforts to develop novel therapies for digestive diseases are increasingly focused on the immune system. This volume reviews the immunopharmacology of the gastrointestinal tract at four distinct levels: Immunomodulation at a cellular level Cellular targers for immunomodulating drugs Specific classes of inflammatory mediators Utility and mechanisms of action of glucocorticoids in the treatment of diseases of the gastrointestinal tract.

Salivary  Gastric  Pancreatic  and Hepatobiliary Secretion Book

Salivary Gastric Pancreatic and Hepatobiliary Secretion

  • Author : John G. Forte
  • Publisher : Amer Physiological Society
  • Release Date : 1989
  • Genre: Science
  • Pages : 779
  • ISBN 10 : 0195208161

Salivary Gastric Pancreatic and Hepatobiliary Secretion Excerpt :

The third volume in The Gastrointestinal System reflects the expansion of knowledge of the cell physiology of secretion. Each chapter, grouped by traditional anatomical location, was written emphasizing the cellular bases of secretion and includes a review of the broader as well as the more integrative aspects of secretion.

Surgical Pathology of Non neoplastic Gastrointestinal Diseases Book

Surgical Pathology of Non neoplastic Gastrointestinal Diseases

  • Author : Lizhi Zhang
  • Publisher : Springer
  • Release Date : 2019-06-24
  • Genre: Medical
  • Pages : 572
  • ISBN 10 : 9783030155735

Surgical Pathology of Non neoplastic Gastrointestinal Diseases Excerpt :

This book covers the entire spectrum of non-neoplastic diseases within the gastrointestinal (GI) tract including new entities, recent developments, and questions that arise in the practice of GI pathology. The text is organized by specific organ site, with related disorders of each organ site subgrouped into several chapters based on their common features. Pathologists can quickly find the disorders they are interested and review similar disorders in the same chapter to help them make a correct diagnosis. Each major and common entity is described in detail with its definition, clinical features, pathological features (covering both the gross and microscopic details), differential diagnosis and treatment/prognosis. All chapters also highlight the use of special/immunohistochemical stains and other supporting studies as needed with a focus on providing a practical differential diagnosis rather than just a list of potential associations. This book is extensively illustrated with both gross and microscopic images that act as an integral part of the information provided in the text. Written by practicing GI/liver pathologists and gastroenterologists from the Mayo Clinic, Surgical Pathology of Non-neoplastic Gastrointestinal Diseases serves as a comprehensive yet practical guide for diagnostic surgical pathologists with a passion for GI pathology.

Gastrointestinal Defence Mechanisms Book

Gastrointestinal Defence Mechanisms

  • Author : Gy. Mózsik
  • Publisher : Elsevier
  • Release Date : 2013-10-22
  • Genre: Health & Fitness
  • Pages : 606
  • ISBN 10 : 9781483190181

Gastrointestinal Defence Mechanisms Excerpt :

Advances in Physiological Sciences, Volume 29: Gastrointestinal Defence Mechanisms is a collection of papers that details the findings of research studies on the theoretical and practical aspects of the gastrointestinal defense mechanisms. The title first covers circulation and mucosal defense, and then proceeds to tackling the association of gastrointestinal mechanisms with the secretory functions. Next, the selection deals with the resistance in gastric mucosa and mucosal energy provision. The text also discusses cell renewal and toxicity, along with biotransformation and nutrition. In Part VII, the title details the immunomechanisms of defense at mucosa. The last part covers the second line defense at liver and enterohepatic circulation. The book will of great interest to both researchers and practitioners of medical fields concerned with the digestive system.

Physiology of the Gastrointestinal Tract  Two Volume Set Book

Physiology of the Gastrointestinal Tract Two Volume Set

  • Author : Hamid M. Said
  • Publisher : Academic Press
  • Release Date : 2012-07-04
  • Genre: Medical
  • Pages : 2308
  • ISBN 10 : 9780123820273

Physiology of the Gastrointestinal Tract Two Volume Set Excerpt :

Physiology of the Gastrointestinal Tract, Fifth Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine — covers the study of the mechanical, physical, and biochemical functions of the GI Tract while linking the clinical disease or disorder, bridging the gap between clinical and laboratory medicine. The gastrointestinal system is responsible for the breakdown and absorption of various foods and liquids needed to sustain life. Other diseases and disorders treated by clinicians in this area include: food allergies, constipation, chronic liver disease and cirrhosis, gallstones, gastritis, GERD, hemorrhoids, IBS, lactose intolerance, pancreatic, appendicitis, celiac disease, Crohn’s disease, peptic ulcer, stomach ulcer, viral hepatitis, colorectal cancer and liver transplants. The new edition is a highly referenced and useful resource for gastroenterologists, physiologists, internists, professional researchers, and instructors teaching courses for clinical and research students. 2013 Highly Commended BMA Medical Book Award for Internal Medicine Discusses the multiple processes governing gastrointestinal function Each section edited by preeminent scientist in the field Updated, four-color illustrations

The Gastrointestinal Circulation Book

The Gastrointestinal Circulation

  • Author : Peter R. Kvietys
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2010
  • Genre: Medical
  • Pages : 127
  • ISBN 10 : 9781615041176

The Gastrointestinal Circulation Excerpt :

The microcirculation of the gastrointestinal tract is under the control of both myogenic and metabolic regulatory systems. The myogenic mechanism contributes to basal vascular tone and the regulation of transmural pressure, while the metabolic mechanism is responsible for maintaining an appropriate balance between O2 demand and O2 delivery. In the postprandial state, hydrolytic products of food digestion elicit a hyperemia, which serves to meet the increased O2 demand of nutrient assimilation. Metabolically linked factors (e.g., tissue pO2, adenosine) are primarily responsible for this functional hyperemia. The fenestrated capillaries of the gastrointestinal mucosa are relatively permeable to small hydrolytic products of food digestion (e.g., glucose), yet restrict the transcapillary movement of larger molecules (e.g., albumin). This allows for the absorption of hydrolytic products of food digestion without compromising the oncotic pressure gradient governing transcapillary fluid movement and edema formation. The gastrointestinal microcirculation is also an important component of the mucosal defense system whose function is to prevent (and rapidly repair) inadvertent epithelial injury by potentially noxious constituents of chyme. Two pathological conditions in which the gastrointestinal circulation plays an important role are ischemia/reperfusion and chronic portal hypertension. Ischemia/reperfusion results in mucosal edema and disruption of the epithelium due, in part, to an inflammatory response (e.g., increase in capillary permeability to macromolecules and neutrophil infiltration). Chronic portal hypertension results in an increase in gastrointestinal blood flow due to an imbalance in vasodilator and vasoconstrictor influences on the microcirculation. Table of Contents: Introduction / Anatomy / Regulation of Vascular Tone and Oxygenation / Extrinsic Vasoregulation: Neural and Humoral / Postprandial Hyperemia / Transcapillary Solute Exchange / Transcapillary Flui

Immunotherapy for Gastrointestinal Malignancies Book

Immunotherapy for Gastrointestinal Malignancies

  • Author : Ramakrishna Vadde
  • Publisher : Springer Nature
  • Release Date : 2021-01-31
  • Genre: Medical
  • Pages : 251
  • ISBN 10 : 9789811564871

Immunotherapy for Gastrointestinal Malignancies Excerpt :

This book reviews current immunotherapeutic strategies for gastrointestinal (GI) malignancies, including immune composition, immune checkpoint inhibitors, cell therapy, and peptide vaccines used to protect against esophageal, gastric, hepato-biliary, pancreatic and colorectal cancers. It also discusses the current challenges of using immunotherapy for the treatment of gastrointestinal malignancies. The book reviews highly sensitive and specific immunomarkers for the detection of GI malignancies, and examines therapeutic vaccines and the major cytokines involved in GI immunotherapy, as well as their basic biology and clinical applications. In closing, the book explores various aspects of computational biology for the detection and treatment of GI malignancies.

Gastrointestinal Oncology Book
Score: 5
From 1 Ratings

Gastrointestinal Oncology

  • Author : James L. Abbruzzese
  • Publisher : Oxford University Press
  • Release Date : 2003-10-23
  • Genre: Medical
  • Pages : 948
  • ISBN 10 : 0199747865

Gastrointestinal Oncology Excerpt :

In 74 chapters, Gastrointestinal Oncology brings together a diverse group of specialists to provide the most authoritative, up-to-date and encyclopedic volume currently available on the subject. The first part of this text introduces a series of concepts and topics taht are important to gastrointestinal malignancies in general. These topics include epidemiologic principles, prevention, screening, familial GI cancers, developmental and molecular biology, pathobiology, general therapeutic principles, emerging therapies, and palliative care. The second part of the book covers each of the specific cancers affecting the human gastrointestinal tract. These chapters are introduced by state of the art discussions outlining our current understanding of the pathobiology and molecular biology relevant to each cancer. Subsequent sections describe the multidisciplinary management of specific clinical situations. By organizing the treatment-related chapters around clinical scenarios, the reader will readily find the information necessary to effectively manage the complex clinical situations encountered by patients with gastrointestinal malignancies.