Green Synthetic Approaches for Biologically Relevant Heterocycles Book

Green Synthetic Approaches for Biologically Relevant Heterocycles


  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2021-03-20
  • Genre: Science
  • Pages : 646
  • ISBN 10 : 9780323851305

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Green Synthetic Approaches for Biologically Relevant Heterocycles Excerpt :

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume One: Advanced Synthetic Techniques reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume One explores advanced synthetic techniques, with each chapter presenting in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles that are classified on the basis of ring-size and/or the presence of heteroatoms. Techniques covered range from high pressure cycloaddition reactions and microwave irradiation to sustainable one-pot domino reactions. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field of greener heterocycle synthesis Includes new chapters on varied multicomponent reactions, alongside both traditional and novel approaches Presents information in an accessible style with an emphasis on sustainability

Green Synthetic Approaches for Biologically Relevant Heterocycles Book

Green Synthetic Approaches for Biologically Relevant Heterocycles


  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2021-02-26
  • Genre: Science
  • Pages : 822
  • ISBN 10 : 9780323851336

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Green Synthetic Approaches for Biologically Relevant Heterocycles Excerpt :

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors

Green Synthetic Approaches for Biologically Relevant Heterocycles Book

Green Synthetic Approaches for Biologically Relevant Heterocycles


  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2014-11-12
  • Genre: Science
  • Pages : 632
  • ISBN 10 : 0128000708

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Green Synthetic Approaches for Biologically Relevant Heterocycles Excerpt :

Green Synthetic Approaches for Biologically Relevant Heterocycles reviews this significant group of organic compounds within the context of sustainable methods and processes. Each clearly structured chapter features in-depth coverage of various green protocols for the synthesis of a wide variety of bioactive heterocycles classified on the basis of ring-size and/or presence of heteratoms(s). Techniques covered include microwave heating, ultrasound, ionic liquids, solid phase, solvent-free, heterogeneous catalysis, and aqueous media, along with multi-component reaction strategies. This book also integrates advances in green chemistry research into industrial applications and process developments. Green Synthetic Approaches for Biologically Relevant Heterocycles is an essential resource on green chemistry technologies for academic researchers, R&D professionals, and students working in medicinal, organic, natural product, and agricultural chemistry. Includes global coverage of a wide variety of green synthetic techniques Features cutting-edge research in the field of bioactive heterocyclic compounds Focuses extensively on applications, with numerous examples of biologically relevant heterocycles

Green Synthetic Approaches for Biologically Relevant Heterocycles Book

Green Synthetic Approaches for Biologically Relevant Heterocycles


  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2021-02-26
  • Genre: Science
  • Pages : 822
  • ISBN 10 : 9780128207925

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Green Synthetic Approaches for Biologically Relevant Heterocycles Excerpt :

Green Synthetic Approaches for Biologically Relevant Heterocycles, Second Edition, Volume Two: Green Catalytic Systems and Solvents reviews this significant group of organic compounds within the context of sustainable methods and processes, expanding on the first edition with fully updated coverage and a whole range of new chapters. Volume Two explores green catalytic systems and solvents and the techniques surrounding this approach, including metal and magnetic catalysis to organocatalysis and solid acid catalysis, cycloaddition reactions, and varied approaches using ionic liquids. This updated edition is an essential resource on sustainable approaches for academic researchers, R&D professionals, and students working across medicinal, organic, natural product and green chemistry. Provides fully updated coverage of the field with an emphasis on sustainability Highlights a range of different eco-friendly solvents and environmentally-friendly catalysts Collates the experience of a global team of expert contributors

Green Chemistry  Synthesis of Bioactive Heterocycles Book

Green Chemistry Synthesis of Bioactive Heterocycles


  • Author : K. L. Ameta
  • Publisher : Springer
  • Release Date : 2014-06-17
  • Genre: Science
  • Pages : 412
  • ISBN 10 : 9788132218500

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Green Chemistry Synthesis of Bioactive Heterocycles Excerpt :

The book presents a succinct summary of methods for the synthesis and biological activities of various different-sized bioactive heterocycles using different green chemistry synthetic methodologies, like microwave, ultrasonic, water mediated, ionic liquids, etc. The book also provides an insight of how green chemistry techniques are specific to the bioactive heterocyclic compounds.

N Heterocycles Book

N Heterocycles


  • Author : Keshav Lalit Ameta
  • Publisher : Springer Nature
  • Release Date : 2022-05-25
  • Genre: Science
  • Pages : 459
  • ISBN 10 : 9789811908323

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N Heterocycles Excerpt :

This book presents an overview of the recent advancements for the synthesis of small- and medium-sized azaheterocycles, including pyrroles, indoles, pyrimidines, pyridines, pyrrolidines, imidazoles, pyrazoles, pyrazolines, lactams, and 1,2,3-triazoles, which are significant scaffolds for compounds with pharmaceutical uses. The book also discusses various properties and performance attributes of azaheterocycles including their bioactivity and synthetic strategies. Given the contents, the book will be a valuable reference for students, researchers, and professionals interested in organic synthesis and medicinal chemistry.

Green Synthetic Processes and Procedures Book

Green Synthetic Processes and Procedures


  • Author : Roberto Ballini
  • Publisher : Royal Society of Chemistry
  • Release Date : 2019-06-28
  • Genre: Science
  • Pages : 432
  • ISBN 10 : 9781788015127

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Green Synthetic Processes and Procedures Excerpt :

The principles of Green Chemistry aim to improve the sustainability of chemical processes and reduce the generation of hazardous substances. There has been great growth in the field over the past few years and the number of research groups working in this area is still increasing. Now one of the biggest challenges is to embed the Green Chemistry ideals of safety and sustainability as standard, both in industry and academia. In order to do this, it is important to create resources that detail different applications and approaches. Green Synthetic Processes and Procedures brings together expert contributors from across a number of areas of green synthesis to cover a diverse array of subjects. Providing a thorough overview of the current green synthetic toolbox, from biocatalysis to sonochemistry, this book is a useful resource for any chemist wishing to design cleaner and safer processes.

Modern Green Chemistry and Heterocyclic Compounds Book

Modern Green Chemistry and Heterocyclic Compounds


  • Author : Ravindra S. Shinde
  • Publisher : CRC Press
  • Release Date : 2020-03-31
  • Genre: Medical
  • Pages : 302
  • ISBN 10 : 9781000029178

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Modern Green Chemistry and Heterocyclic Compounds Excerpt :

This book covers the general properties of heterocyclic compounds and methods for their preparation to use in applications of green chemistry. Heterocyclic compounds are an important class of molecules in organic chemistry due to their presence in natural products and their use in pharmaceuticals and new materials. They also play a vital role in the metabolism of living cells. Heterocyclic compounds have a wide range of applications in agrochemicals, pharmaceuticals, veterinary products, etc. This research-oriented volume is ideal for readers who want to fully realize the almost limitless potential of heterocyclic compounds and to discover new and effective pharmaceuticals among heterocyclic compounds, the largest and most varied family of organic compounds. The book features several case studies and step-by-step descriptions of synthetic methods and practical techniques. It also serves as a guide for chemists, offering them new insights and new paths to explore for effective drug discovery.

Multicomponent Reactions towards Heterocycles Book

Multicomponent Reactions towards Heterocycles


  • Author : Erik Van der Eycken
  • Publisher : John Wiley & Sons
  • Release Date : 2021-11-22
  • Genre: Science
  • Pages : 624
  • ISBN 10 : 9783527832446

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Multicomponent Reactions towards Heterocycles Excerpt :

Presents a wide-ranging overview of essential topics and recent advances in MCR chemistry Heterocycles are a central component in natural product chemistry, pharmaceuticals, agrochemicals, and material science. New synthetic methodologies integrating the sequencing of multicomponent reactions (MCRs) are today being used for the rapid synthesis of diversified heterocycles in just one step. Multicomponent Reactions towards Heterocycles presents an up-to-date summary MCR chemistry with a focus on the conjugation between modern synthetic methodologies and MCRs. Featuring contributions by leaders in the field, this comprehensive resource highlights applications of MCRs in natural products and intermediate synthesis, discusses current trends and future prospects in MCR chemistry, outlines novel multicomponent procedures, and more. The authors provide the practical information required for designing new reaction strategies and mechanisms, covering topics including MCR-based green synthetic methods, cyclization and cycloaddition reactions, heterocycle multicomponent syntheses in a continuous flow, catalytic alkynoyl generation, MCR synthesis of saturated heterocycles, and C–H functionalization and multicomponent reactions. Provides a thorough overview of heterocycles as input in multicomponent reactions Discusses recent advances in the field of MCR chemistry and progress in the synthesis and functionalization of heterocycles Demonstrates the use of MCRs to simplify synthetic design and achieve complexity and diversity in novel bioactive molecules Highlights examples of multicomponent polymerizations, target-oriented synthesis, and applications of MCR in medicinal chemistry Explains the methodology of using on-resin MCRs to produce heterocycle compounds Illustrating the key role of MCRs towards heterocycles in natural product synthesis, drug discovery, organic synthesis, and other applications, Multicomponent Reactions towards Heterocycles is required reading for synthetic

Catalyst free Organic Synthesis Book

Catalyst free Organic Synthesis


  • Author : Goutam Brahmachari
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-11-06
  • Genre: Uncategoriezed
  • Pages : 392
  • ISBN 10 : 9781782624127

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Catalyst free Organic Synthesis Excerpt :

Green Approaches in Medicinal Chemistry for Sustainable Drug Design Book

Green Approaches in Medicinal Chemistry for Sustainable Drug Design


  • Author : Bimal K. Banik
  • Publisher : Elsevier
  • Release Date : 2020-03-27
  • Genre: Medical
  • Pages : 1044
  • ISBN 10 : 9780128175934

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Green Approaches in Medicinal Chemistry for Sustainable Drug Design Excerpt :

Extensive experimentation and high failure rates are a well-recognised downside to the drug discovery process, with the resultant high levels of inefficiency and waste producing a negative environmental impact. Sustainable and Green Approaches in Medicinal Chemistry reveals how medicinal and green chemistry can work together to directly address this issue. After providing essential context to the growth of green chemistry in relation to drug discovery in Part 1, the book goes on to identify a broad range of practical methods and synthesis techniques in Part 2. Part 3 reveals how medicinal chemistry techniques can be used to improve efficiency, mitigate failure and increase the environmental benignity of the entire drug discovery process, whilst Parts 4 and 5 discuss natural products and microwave-induced chemistry. Finally, the role of computers in drug discovery is explored in Part 6. Identifies novel and cost effective green medicinal chemistry approaches for improved efficiency and sustainability Reflects on techniques for a broad range of compounds and materials Highlights sustainable and green chemistry pathways for molecular synthesis

Room Temperature Organic Synthesis Book

Room Temperature Organic Synthesis


  • Author : Goutam Brahmachari
  • Publisher : Elsevier
  • Release Date : 2015-03-19
  • Genre: Science
  • Pages : 386
  • ISBN 10 : 9780128011386

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Room Temperature Organic Synthesis Excerpt :

Filling a gap in the scientific literature, Room Temperature Organic Synthesis is unique in its authoritative, thorough, and applied coverage of a wide variety of "green" organic synthetic methodologies. The book describes practical, feasible protocols for room temperature reactions to produce carbon-carbon and carbon-heteroatom bond formations including aliphatic, aromatic, alicyclic, heterocycles, and more. Consistently organized for easy access, each selected reaction is discussed in a very compact and structured manner including: reaction type, reaction condition, reaction strategy, catalyst, keywords, general reaction scheme, mechanism (in selected cases), representative entries, experimental procedure, characterization data of representative entries, and references. This book will be a valuable resource for synthetic organic, natural products, medicinal, and biochemists as well as those working in the pharmaceutical and agrochemical industry. Includes more than 300 protocols for a green approach to organic synthesis Provides specific detail about experimental conditions Increases efficiency in the laboratory by eliminating time-consuming literature searches

Bio Based Solvents Book

Bio Based Solvents


  • Author : François Jérôme
  • Publisher : John Wiley & Sons
  • Release Date : 2017-06-29
  • Genre: Science
  • Pages : 200
  • ISBN 10 : 9781119065449

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Bio Based Solvents Excerpt :

A multidisciplinary overview of bio-derived solvent applications, life cycle analysis, and strategies required for industrial commercialization This book provides the first and only comprehensive review of the state-of-the-science in bio-derived solvents. Drawing on their own pioneering work in the field, as well as an exhaustive survey of the world literature on the subject, the authors cover all the bases—from bio-derived solvent applications to life cycle analysis to strategies for industrial commercialization—for researchers and professional chemists working across a range of industries. In the increasingly critical area of sustainable chemistry, the search for new and better green solvents has become a top priority. Thanks to their renewability, biodegradability and low toxicity, as well as their potential to promote advantageous organic reactions, green solvents offer the promise of significantly reducing the pernicious effects of chemical processes on human health and the environment. Following an overview of the current solvents markets and the challenges and opportunities presented by bio-derived solvents, a series of dedicated chapters cover all significant classes of solvent arranged by origin and/or chemical structure. Throughout, real-world examples are used to help demonstrate the various advantages, drawbacks, and limitations of each class of solvent. Topics covered include: The commercial potential of various renewably sourced solvents, such as glycerol The various advantages and disadvantages of bio-derived versus petroleum-based solvents Renewably-sourced and waste-derived solvents in the design of eco-efficient processes Life cycle assessment and predictive methods for bio-based solvents Industrial and commercial viability of bio-based solvents now and in the years ahead Potential and limitations of methodologies involving bio-derived solvents New developments and emerging trends in the field and the shape of things to come Considering the vas

Multicomponent Reactions Book

Multicomponent Reactions


  • Author : K.L. Ameta, Ph.D.
  • Publisher : CRC Press
  • Release Date : 2017-09-20
  • Genre: Medical
  • Pages : 598
  • ISBN 10 : 9781315352732

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Multicomponent Reactions Excerpt :

This timely book provides a succinct summary of methods for the synthesis of bioactive heterocycles using a multicomponent reaction (MCR) approach. The majority of pharmaceuticals and biologically active agrochemicals are heterocycles while countless additives and modifiers used in industrial applications are heterocyclic in nature. With the recent introduction of high-throughput biological evaluation, the importance of MCRs for drug discovery has been recognized and considerable efforts have been focused especially on the design and development of multi-component procedures for the generation of various bioactive heterocycles due to their significant therapeutic potential.