Handbook of Developmental Neurotoxicology Book

Handbook of Developmental Neurotoxicology


  • Author : William Slikker, Jr.
  • Publisher : Academic Press
  • Release Date : 2018-01-04
  • Genre: Science
  • Pages : 616
  • ISBN 10 : 9780128093948

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Handbook of Developmental Neurotoxicology Excerpt :

Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience. Presents a comprehensive, up-to-date resource on developmental neurotoxicology with updated chapters from the first edition Contains new chapters that focus on subjects recent to the field Includes well-illustrated material, with diagrams, charts, and tables Contains compelling case studies and chapters written by world experts

The Laboratory Rat Book

The Laboratory Rat


  • Author : George J. Krinke
  • Publisher : Elsevier
  • Release Date : 2000-06-20
  • Genre: Medical
  • Pages : 756
  • ISBN 10 : 0080533469

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The Laboratory Rat Excerpt :

This reference series will provide all researchers using laboratory animals with comprehensive practical information on the various species. Each title in the series is devoted to a particular species, and draws together all available data in a "one-stop", easily accessible source. Each has similar format, with sections on the strains available, their husbandry, and special diets. Also included are sections on gross anatomy, endocrinology, and reproduction, followed by more detailed sections on neuroanatomy, vasculature, cell biology, and histology of particular organs and structures, and a section on molecular biology. High quality illustrations are included throughout and a color plate section is provided. A glossary, list of equipment suppliers, and "Quick Reference Section" are added features. The "Quick Reference Section" brings together all tables from the text, allowing readers to find data swiftly. The first volume in The Handbook of Experimental Animals Series, The Laboratory Rat, provides researchers in academia and industry using laboratory animals with comprehensive, practical information on the species. The Laboratory Rat has been divided into eight sections dealing with: * Strains and their selection for research * Housing and maintenance * Pathogens and diseases * Breeding and reproduction * Anatomy * Physiology * Procedures, including experimental surgery * Emerging techniques, including genetic engineering and molecular technology Key Features * Provides a valuable, comprehensive reference source for anybody working with the laboratory rat * Formatted in a two-color, user-friendly layout * Includes high-quality illustrations throughout as well as a color plate section * Glossary * Tables in the text are also arranged into one Quick Reference Section for ease of access to the data * Appendix of equipment suppliers

Haschek and Rousseaux s Handbook of Toxicologic Pathology Book

Haschek and Rousseaux s Handbook of Toxicologic Pathology


  • Author : Wanda M. Haschek
  • Publisher : Academic Press
  • Release Date : 2013-05-01
  • Genre: Medical
  • Pages : 3054
  • ISBN 10 : 9780124157651

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Haschek and Rousseaux s Handbook of Toxicologic Pathology Excerpt :

Haschek and Rousseaux's Handbook of Toxicologic Pathology is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals and biologics. The 3e has been expanded by a full volume, and covers aspects of safety assessment not discussed in the 2e. Completely revised with many new chapters, it remains the most authoritative reference on toxicologic pathology for scientists and researchers studying and making decisions on drugs, biologics, medical devices and other chemicals, including agrochemicals and environmental contaminants. New topics include safety assessment, the drug life cycle, risk assessment, communication and management, carcinogenicity assessment, pharmacology and pharmacokinetics, biomarkers in toxicologic pathology, quality assurance, peer review, agrochemicals, nanotechnology, food and toxicologic pathology, the environment and toxicologic pathology and more. Provides new chapters and in-depth discussion of timely topics in the area of toxicologic pathology and broadens the scope of the audience to include toxicologists and pathologists working in a variety of settings Offers high-quality and trusted content in a multi-contributed work written by leading international authorities in all areas of toxicologic pathology Features hundreds of full color images in both the print and electronic versions of the book to highlight difficult concepts with clear illustrations

Environmental Health Perspectives Book

Environmental Health Perspectives


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1993
  • Genre: Environmental health
  • Pages : null
  • ISBN 10 : MINN:30000010711418

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Environmental Health Perspectives Excerpt :

Handbook of Toxicology Book

Handbook of Toxicology


  • Author : Michael J. Derelanko
  • Publisher : CRC Press
  • Release Date : 2014-03-07
  • Genre: Law
  • Pages : 1022
  • ISBN 10 : 9781439890141

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Handbook of Toxicology Excerpt :

The Handbook of Toxicology, Third Edition provides an updated practical reference source for practicing toxicologists in the pharmaceutical and chemical industries, contract laboratories, regulatory agencies, and academia. Written by experts in their specific toxicology fields, the chapters provide both fundamental and applied information. Topics r

Developmental and Reproductive Toxicology Book

Developmental and Reproductive Toxicology


  • Author : Ronald D. Hood
  • Publisher : CRC Press
  • Release Date : 2005-08-30
  • Genre: Medical
  • Pages : 1168
  • ISBN 10 : 9781420040548

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Developmental and Reproductive Toxicology Excerpt :

Completely revised and updated, Developmental and Reproductive Toxicology: A Practical Approach, Second Edition draws together valuable information typically scattered throughout the literature, plus some not previously published, into one complete resource. In addition to the traditional aspects of developmental toxicity testing, the book covers evaluating and interpreting data. Originally titled Handbook of Developmental Toxicology, the second edition's new name reflects significant changes in its content and scope. New coverage in the Second Edition: Genomics and proteomics Tests for endocrine disruptors Testing for male and female reproductive toxicity Extensive treatment of the significance, reliability, and interpretation of developmental and reproductive toxicity data Toxicity testing in neonatal and juvenile animals Postnatal developmental milestones FDA perspective on risk assessment Extensive glossaries of developmental defect terminology Previous books on this subject have largely been academically oriented and not intended to guide the practicing developmental or reproductive toxicologist. Useful and informative, this book blends the theoretical foundation with insights gained from hands-on experience. It includes tables of comparative developmental milestones - both pre- and postnatal, glossaries of descriptive terms used in developmental toxicity evaluation, and both US and international regulatory guidelines. Bridging the gap between theory and application, this is a handy single-source of essential information to use in planning, conducting, and interpreting studies.

Information Resources in Toxicology Book

Information Resources in Toxicology


  • Author : Steve Gilbert
  • Publisher : Academic Press
  • Release Date : 2020-05-16
  • Genre: Medical
  • Pages : 1054
  • ISBN 10 : 9780128137253

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Information Resources in Toxicology Excerpt :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving incre

In Vitro Neurotoxicology Book

In Vitro Neurotoxicology


  • Author : Evelyn Tiffany-Castiglioni
  • Publisher : Springer Science & Business Media
  • Release Date : 2004
  • Genre: Medical
  • Pages : 352
  • ISBN 10 : 9781592596515

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In Vitro Neurotoxicology Excerpt :

Well-respected leaders in the field of in vitro neurotoxicology take a fresh look at their own and other's work, critically and comparatively analyzing it across experimental systems and toxicants, and synthesizing essential principles for in vitro neurotoxicity testing. Neurotoxicants of significance to human health are emphasized, especially those for which metabolism and dose-responses are well well studied both in vivo and in vitro: lead, mercury, organophosphorous insecticides, polychlorinated biphenyls and dioxin, ethanol, and endogenous proteins. The goal is to set out new concepts and research directions that will hasten significant improvement in the methods and systems for in vitro neurotoxicity testing.

Handbook of Arsenic Toxicology Book
Score: 5
From 1 Ratings

Handbook of Arsenic Toxicology


  • Author : Swaran Jeet Singh Flora
  • Publisher : Academic Press
  • Release Date : 2014-12-26
  • Genre: Medical
  • Pages : 752
  • ISBN 10 : 9780124199552

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Handbook of Arsenic Toxicology Excerpt :

Throughout history, arsenic has been used as an effective and lethal poison. Today, arsenic continues to present a real threat to human health all over the world, as it contaminates groundwater and food supplies. Handbook of Arsenic Toxicology presents the latest findings on arsenic, its chemistry, its sources and its acute and chronic effects on the environment and human health. The book takes readings systematically through the target organs, before detailing current preventative and counter measures. This reference enables readers to effectively assess the risks related to arsenic, and provide a comprehensive look at arsenic exposure, toxicity and toxicity prevention. Brings together current findings on the effects of arsenic on the environment and human health Includes state-of-the-art techniques in arsenic toxicokinetics, speciation and molecular mechanisms Provides all the information needed for effective risk assessment, prevention and countermeasure

Molecular Neurotoxicology Book

Molecular Neurotoxicology


  • Author : Nasser H. Zawia
  • Publisher : CRC Press
  • Release Date : 2004-04-27
  • Genre: Medical
  • Pages : 248
  • ISBN 10 : 9780203503317

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Molecular Neurotoxicology Excerpt :

Molecular Neurotoxicology: Environmental Agents and Transcription-Transduction Coupling deals with changes in gene expression following exposure to neurotoxicants, as well as deciphering signal transduction or transcription coupling that is altered by the same exposure. Until now, little has been published on the topic in one reference, and toxicol

Handbook of Neurotoxicity Book

Handbook of Neurotoxicity


  • Author : Richard Kostrzewa
  • Publisher : Springer
  • Release Date : 2014-06-04
  • Genre: Medical
  • Pages : 2371
  • ISBN 10 : 1461458358

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Handbook of Neurotoxicity Excerpt :

The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments – to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities. Neuroprotection is approached in different manners including those 1) afforded by therapeutic agents – clinical and preclinical; or 2) by non-drug means, such as exercise. The amorphous term ‘neurotoxin’ is discussed in terms of the possible eventuality of a neuroprotectant producing an outcome of excess neuronal survival and a behavioral spectrum that might produce a dysfunction – akin to a neurotoxin’s effect. The Handbook of Neurotoxicity is thus an instructive and valuable guide towards understanding the role of neurotoxins/neurotoxicity in the expansive field of Neuroscience, and is an indispensable tool for laboratory investigators, neuroscientists, and clinical researchers.

Developmental Neurotoxicology Book

Developmental Neurotoxicology


  • Author : G Jean Harry
  • Publisher : CRC Press
  • Release Date : 1994-07-13
  • Genre: Medical
  • Pages : 192
  • ISBN 10 : 1439805504

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Developmental Neurotoxicology Excerpt :

Developmental Neurotoxicology addresses a number of basic principles underlying the vulnerability of the developing nervous system to environmental toxicant exposure. Evidence of functional alterations, induced at levels of chemical exposure that fail to produce structural teratological alterations, indicates that the evaluation of the functional capacity of exposed animals may indeed offer a sensitive evaluation of developmental toxicity. The contributing authors discuss the basic principles of development in structure and functional components and present information covering various methodological approaches, as well as evidence for the value of examining the developing nervous system for environmentally induced perturbations. The final chapter covers how this type of data is used to evaluate human risk potential.

Neurotoxicology Book

Neurotoxicology


  • Author : Louis W. Chang
  • Publisher : Elsevier
  • Release Date : 1995-04-20
  • Genre: Science
  • Pages : 851
  • ISBN 10 : 9780080537474

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Neurotoxicology Excerpt :

Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. Discusses neurobehavioral testing methods for assessment of neural dysfunctions Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity Presents step-by-step procedures for many methods Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation

Information Resources in Toxicology Book

Information Resources in Toxicology


  • Author : P.J. Bert Hakkinen
  • Publisher : Academic Press
  • Release Date : 2000
  • Genre: Medical
  • Pages : 921
  • ISBN 10 : 9780127447704

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Information Resources in Toxicology Excerpt :

History: -- K.D. Watson, P. Wexler, and J. Everitt. -- Highlights in the History of Toxicology. -- Selected References in the History of Toxicology. -- A Historical Perspective of Toxicology Information Systems. -- Books and Special Documents: -- G.L. Kennedy, Jr., P. Wexler, N.S. Selzer, and L.A. Malley. -- General Texts. -- Analytical Toxicology. -- Animals in Research. -- Biomonitoring/Biomarkers. -- Biotechnology. -- Biotoxins. -- Cancer. -- Chemical Compendia. -- Chemical--Cosmetics and Other Consumer. -- Products. -- Chemical--Drugs. -- Chemical--Dust and Fibers. -- Chemical--Metals. -- Chemicals--Pesticides -- Chemicals--Solvents. -- Chemical--Selected Chemicals. -- Clinical Toxicology. -- Developmental and Reproductive Toxicology. -- Environmental Toxicology--General. -- Environmental Toxicology-- Aquatic. -- Environmental Toxicology--Atmospheric. -- Environmental Toxicology--Hazardous Waste. -- Environmental Toxicology--Terrestrial. -- Environmental Toxicology--Wildlife. -- Ep ...

Predictive Toxicology in Drug Safety Book

Predictive Toxicology in Drug Safety


  • Author : Jinghai J. Xu
  • Publisher : Cambridge University Press
  • Release Date : 2010-09-27
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9781139493093

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Predictive Toxicology in Drug Safety Excerpt :

According to the Institute of Medicine (IOM) and U.S. Food and Drug Administration (FDA), 'developing new scientific approaches to detecting, understanding, predicting and preventing adverse events' was a critical path to the future of drug safety. This book brings together a collection of state-of-the-art chapters, written by experts in the drug safety field. It provides information on the present knowledge of drug side effects and their mitigation strategy during drug discovery, gives guidance for risk assessment and promotes evidence-based toxicology. Each specific area of toxicology relevant for drug discovery is discussed in detail, including theory, experimental approaches and data interpretation supported by comprehensive up-to-date references. Many chapters provide fascinating case studies, which are of general interest for those who have basic science training and are interested in how chemicals interact with the human body.