Handbook of Microdialysis Book

Handbook of Microdialysis


  • Author :
  • Publisher : Elsevier
  • Release Date : 2007-02-02
  • Genre: Psychology
  • Pages : 712
  • ISBN 10 : 9780080469669

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Handbook of Microdialysis Book Description :

Microdialysis is currently one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to behavior, hormonal and transmitter changes in the nervous system. The book provides a detailed comprehensive overview of the technology and its applications, including application in pathology, drug development, and the application in the clinic. The authors are all well known researchers in Neuroscience and experts in the use of Microdialysis. Organized into two parts of seven sections, the Handbook of Microdialysis critically examines recent developments in the field through a variety of chapters written by an internationally acclaimed group of authors. It is the first comprehensive handbook covering the technology of Microdialysis and its applications in Neuroscience. * Presents microdialysis methods and interpretation including the technical aspects of microdialysis as a sampling technique followed by the analytical chemical methods * Discusses the role of microdialysis in pharmacology, drug development and models of CNS pathology * Includes clinical applications of microdialysis

Handbook of Microdialysis Book

Handbook of Microdialysis


  • Author : B. H. C. Westerink
  • Publisher : Elsevier
  • Release Date : 2007
  • Genre: Medical
  • Pages : 697
  • ISBN 10 : 9780444522764

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Handbook of Microdialysis Book Description :

Contributions are: 'Interpretation and Significance', 'Methods', 'Analytical Chemical Aspects of Microdialysis', 'Microdialysis and the Study of Behaviour', 'CNS Pathology Models', 'Role of Microdialysis in Drug Development' and 'Clinical Applications'.

Handbook of Non Invasive Methods and the Skin  Second Edition Book

Handbook of Non Invasive Methods and the Skin Second Edition


  • Author : Jorgen Serup
  • Publisher : CRC Press
  • Release Date : 2006-02-23
  • Genre: Medical
  • Pages : 1056
  • ISBN 10 : 9781420003307

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Handbook of Non Invasive Methods and the Skin Second Edition Book Description :

Firmly established as the leading international reference in this field, Non-Invasive Methods and the Skin broke new ground with its comprehensive coverage of methods used in both clinical and experimental dermatology. Completely revised and updated, containing more than twice as much information, the Second Edition continues the tradition. The authors' thorough research and clear organization make this book a baseline reference for those using noninvasive biophysical methods to study the skin. Arranged by physical modality and structured to provide educational and practical information, the second edition, like its predecessor, will prove to be of value to young researchers and senior scientists alike. The coverage of major evaluation and measurement methods share a consistent format, including scope, sources of error, application, and validity. This edition incorporates 69 revised chapters with more than 90 new chapters covering topics such as computer technique, imaging techniques, skin friction, barrier functions, and more. New chapters provide coverage of: computers, computer techniques, and image analysis imaging techniques, including clinical photography legal situations and guidelines behind instrumental use skin friction barrier functions important new techniques such as in vitro confocal microscopy, OCT, and Raman spectroscopy veterinary/animal research use of methods The truly interdisciplinary, international panel of contributors includes experts from the specialties of dermatology, bioengineering, pathology, manufacturing engineering, medical physics, pharmacology, microbiology, neurology, surgery, obstetrics and gynecology, cardiovascular research, and pharmacy from academic institutions and hospitals in countries such as Denmark, Germany, the United Kingdom, the United States, Japan, Israel, Taiwan, and Singapore. The revision is extensive and covers a broad spectrum of methods while providing the same caliber of authoritative information that made th

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics


  • Author : Michelle A. Rudek
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-01-10
  • Genre: Medical
  • Pages : 836
  • ISBN 10 : 9781461491354

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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book Description :

There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading investigators synthesize an invaluable overview of the experimental and clinical processes of anticancer drug development, creating a single indispensable reference that covers all the steps from the identification of cancer-specific molecular targets to screening techniques and the development and validation of bioanalytical methods to clinical trial design and all phases of clinical trials. The authors have included new material on phase 0 trials in oncology, organ dysfunction trials, drug formulations and their impact on anticancer drug PK/PD including strategies to improve drug delivery, pharmacogenomics and cancer therapy, high throughput platforms in drug metabolism and transport pharmacogenetics, imaging in drug development and nanotechnology in cancer. Authoritative and up-to-date, Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, 2nd Edition provides in one comprehensive and highly practical volume a detailed step-by-step guide to the successful design and approval of anticancer drugs. Road map to anticancer drug development from discovery to NDA submission Discussion of molecular targets and preclinical screening Development and validation of bioanalytical methods Chapters on clinical trial design and phase 0, I, II, III clinical trials Pharmacokinetics, pharmacodynamics, pharmacogenomics, and pharmacogenetics of anticancer agents Review of the drug development process from both laboratory and clinical perspectives New technological advances in imaging, high throughput platforms, and nanotechnology in anticancer drug development

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book

Handbook of Anticancer Pharmacokinetics and Pharmacodynamics


  • Author : William D. Figg
  • Publisher : Springer Science & Business Media
  • Release Date : 2004-03-26
  • Genre: Medical
  • Pages : 623
  • ISBN 10 : 9781592597345

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Handbook of Anticancer Pharmacokinetics and Pharmacodynamics Book Description :

Leading investigators synthesize the entire laboratory and clinical process of developing anticancer drugs to create a single indispensable reference that covers all the steps from the identification of cancer-specific targets to phase III clinical trials. These expert authors provide their best guidance on a wide variety of issues, including clinical trial design, preclinical screening, and the development and validation of bioanalytic methods. The chapters on identifying agents to test in phase III trials and on trial design for the approval of new anticancer agents offer a unique roadmap for moving an agent to NDA submission.

Handbook of Capillary Electrophoresis  Second Edition Book
Score: 5
From 1 Ratings

Handbook of Capillary Electrophoresis Second Edition


  • Author : James P. Landers
  • Publisher : CRC Press
  • Release Date : 1996-12-23
  • Genre: Medical
  • Pages : 894
  • ISBN 10 : 084932498X

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Handbook of Capillary Electrophoresis Second Edition Book Description :

Because new information was discovered at an incredible rate since the publication of the successful first edition of this Handbook, this fully updated second edition covers all areas of interest in the field of capillary electrophoresis (CE). A relatively new technology, CE is a principle method for studying the physicochemical properties of proteins, peptides, and other macromolecules. Where applicable, the 30 chapters provide basic underlying theories as well as application-oriented aspects of each technique.Keep up with all the developments in this growing field with the Handbook of Capillary Electrophoresis, Second Edition - a complete guide to the fundamentals of CE and the latest research. The chapters are organized into five units: Modes: Presents a theoretical development of the basic principles governing separation with several modes, including CEC, and discusses their practical aspects. Analyte: Applies CE to the analysis of a specific class of analytes, including organic and inorganic ions, pharmaceuticals, glycoconjugates, peptides, proteins, and DNA fragments. Fundamental Aspects of CE: Technique-oriented information for the practitioner, including the importance of the sample matrix, on-line preconcentration of samples, modes of detection, and specific aspects of CE data analysis. Applications of CE: Includes single cell analysis, CE in DNA sequencing, CE as a clinical diagnostic tool, identifying and quantifying drugs, and for characterizing interacting species. Specialized Aspects of CE: Discusses interfacing CE with mass spectrometry, high-volume throughput continuous CE, microchip CE, control of EOF, and much more. The Handbook of Capillary Electrophoresis, Second Edition, pulls together diverse areas and applications of CE, resulting in an excellent tool for scientists involved in biotechnology and clinical chemistry, as well as the pharmaceutical, bioscience, chemical, and instrument-manufacturing industries. With an applications-oriented focus,

Handbook of Solid Phase Microextraction Book

Handbook of Solid Phase Microextraction


  • Author : Janusz Pawliszyn
  • Publisher : Elsevier
  • Release Date : 2011-11-29
  • Genre: Science
  • Pages : 496
  • ISBN 10 : 9780123914491

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Handbook of Solid Phase Microextraction Book Description :

The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner

Handbook of ICU EEG Monitoring Book
Score: 5
From 1 Ratings

Handbook of ICU EEG Monitoring


  • Author : Suzette M. M LaRoche, MD
  • Publisher : Demos Medical Publishing
  • Release Date : 2012-12-20
  • Genre: Medical
  • Pages : 160
  • ISBN 10 : 9781617050787

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Handbook of ICU EEG Monitoring Book Description :

The emerging technology of continuous EEG monitoring in intensive care units gives practitioners the ability to identify malignant EEG patterns quickly and provide more effective care. Handbook of ICU EEG Monitoring encompasses the wide range of technical and clinical issues involved in the successful monitoring of critically ill patients to detect significant changes in cerebral function and prevent serious neuronal injury. Divided into five sections, the handbook covers EEG acquisition and other technical considerations, clinical indications, EEG interpretation, appropriate treatment, and practical and administrative concerns. The book addresses the often overlooked subjects of billing, coding, and generating reports to facilitate communication across the entire ICU team. Written by leading experts in this rapidly evolving field, the chapters are brief and formatted for maximum utility with bulleted text, pearls, and take-home points to reinforce key information. High-quality examples of routine and quantitative EEG findings help users hone their interpretive understanding and build skills for detecting clinically significant EEG changes in the ICU. Handbook of ICU EEG Monitoring Features: Broad but practical reference covering all aspects of ICU EEG monitoring Thorough discussion of the indications for ICU EEG monitoring and prevalence of seizures in patient subgroups Focus on the challenges of EEG interpretation that are unique to EEG monitoring in the ICU Pearls and take-home points highlighted in every chapter Includes hard-to-find information on technical aspects, indications, billing and coding, and other administrative and procedural concerns Handbook of ICU EEG Monitoring is the first practical but comprehensive resource dedicated to the art and science of EEG monitoring in the ICU. Neurologists, neurointensivists, neurosurgeons, nursing staff, EEG technologists, and anyone caring for critically patients will find pertinent and pivotal information to infor

Handbook of Neurosurgery Book

Handbook of Neurosurgery


  • Author : Mark S. Greenberg
  • Publisher : Thieme
  • Release Date : 2010-02-01
  • Genre: Medical
  • Pages : 1352
  • ISBN 10 : 9781604063271

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Handbook of Neurosurgery Book Description :

A must-have...[a] low-cost, highly portable, and extremely useful reference volume, which will undoubtedly enjoy continued longevity into the foreseeable future.--Journal of NeurosurgeryA vital resource...For rapid access to the diagnosis and management of all neurosurgical things, there is no substitute.--The Journal of TRAUMA Injury, Infection, and Critical CareFor two decades, Handbook of Neurosurgery -- now in a fully updated seventh edition -- has been an invaluable companion for every neurosurgery resident and nurse, as well as neurologists and others involved in the care of patients with brain and spine disorders. Dr. Greenberg's classic text covers the breadth of neurosurgery and its allied specialties and provides the latest information on anatomy and physiology, differential diagnosis, and currently accepted principles of clinical management. Renowned for its scope and accessibility, this portable, single-volume guide is packed with more than 1,300 pages of practical information, including thousands of literature citations, handy cross-references, and a thorough index.Features: New to the seventh edition: detailed coverage of blunt cervical arterial injuries; awake craniotomies; brain mapping; new grading systems for cervical and thoracolumbar fractures; radiation safety for neurosurgeons; organ donation after cardiac death; and expanded discussion of endovascular techniques Numerous updates, including information on dural arteriovenous malformations; tumors and molecular biology; and new neuromonitoring modalities such as brain oxygen tension, cerebral microdialysis, and regional cerebral blood flow The return of basic surgical material to acquaint readers with the operating room A practical new feature called Booking the Case supplies helpful information about scheduling surgery and obtaining informed consent Highly valuable section on hot topics in neurocritical care Color highlights and full-color inserts to enhance readability Comprehensive and conven

Applications of Microdialysis in Pharmaceutical Science Book

Applications of Microdialysis in Pharmaceutical Science


  • Author : Tung-Hu Tsai
  • Publisher : John Wiley & Sons
  • Release Date : 2011-07-13
  • Genre: Medical
  • Pages : 584
  • ISBN 10 : 1118011287

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Applications of Microdialysis in Pharmaceutical Science Book Description :

Discover new and emerging applications for microdialysis in drug evaluation Microdialysis is a highly valuable sampling tool that can be used in vivo to measure free, unbound analyte concentrations located in interstitial and extracellular spaces. This book explores the full range of clinical applications for microdialysis, focusing on its use in different organ and tissue systems for pharmacokinetic and pharmacodynamic studies. Readers gain a full understanding of the underlying science of microdialysis, current techniques and practices, as well as its many applications in pharmaceutical research. Applications of Microdialysis in Pharmaceutical Science starts with an introduction to basic principles and then covers analytical considerations, pharmacodynamic and pharmacokinetic studies, clinical aspects, and special applications. Topics include: Role of microdialysis in drug development, including crucial sampling considerations and applications for nervous system diseases Continuous measurement of glucose concentrations in diabetics Applications for clinical evaluation and basic research on organ systems, including monitoring exogenous and endogenous compounds in the lungs Pharmacokinetic and pharmacodynamic evaluation of anticancer drugs Comparison of microdialysis with imaging approaches to evaluate in vivo drug distribution Special applications of microdialysis in studies of cell culture assays, drug-drug interactions, and environmental monitoring Throughout the book, readers will find simple models that clarify complex concepts and easy-to-follow examples that guide them through key applications in pharmaceutical research. In short, this book enables pharmaceutical researchers to take full advantage of microdialysis techniques for the preclinical and clinical evaluation of drugs and much more.

Chemical Analysis Book

Chemical Analysis


  • Author : David D. Cunningham
  • Publisher :
  • Release Date : 1941
  • Genre: Biosensors
  • Pages : 450
  • ISBN 10 : CHI:092101800

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Chemical Analysis Book Description :

Handbook of Spectroscopy Book

Handbook of Spectroscopy


  • Author : G¿nter Gauglitz
  • Publisher : John Wiley & Sons
  • Release Date : 2014-05-05
  • Genre: Science
  • Pages : 1993
  • ISBN 10 : 9783527654727

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Handbook of Spectroscopy Book Description :

This second, thoroughly revised, updated and enlarged edition provides a straightforward introduction to spectroscopy, showing what it can do and how it does it, together with a clear, integrated and objective account of the wealth of information that may be derived from spectra. It also features new chapters on spectroscopy in nano-dimensions, nano-optics, and polymer analysis. Clearly structured into sixteen sections, it covers everything from spectroscopy in nanodimensions to medicinal applications, spanning a wide range of the electromagnetic spectrum and the physical processes involved, from nuclear phenomena to molecular rotation processes. In addition, data tables provide a comparison of different methods in a standardized form, allowing readers to save valuable time in the decision process by avoiding wrong turns, and also help in selecting the instrumentation and performing the experiments. These four volumes are a must-have companion for daily use in every lab.

Handbook of Clinical Automation  Robotics  and Optimization Book

Handbook of Clinical Automation Robotics and Optimization


  • Author : Gerald J. Kost
  • Publisher : Wiley-Interscience
  • Release Date : 1996
  • Genre: Computers
  • Pages : 952
  • ISBN 10 : UOM:39015038159078

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Handbook of Clinical Automation Robotics and Optimization Book Description :

This comprehensive landmark book describes the technology of the future in diagnostic medicine, how to integrate it into the modern hospital and how to work with people to adapt, change and plan for a smooth transition to a fully robotic laboratory. Features an extensive section on point-of-care testing along with a modern perspective of how this will transform medicine. Global experts in their fields have authored all chapters which include a unique one on machine vision and another (with several plates) that discusses the automation of a clinical laboratory in Japan.

Neurotransmitters and Neuromodulators Book

Neurotransmitters and Neuromodulators


  • Author : Oliver von Bohlen und Halbach
  • Publisher : John Wiley & Sons
  • Release Date : 2006-12-13
  • Genre: Medical
  • Pages : 402
  • ISBN 10 : 9783527609079

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Neurotransmitters and Neuromodulators Book Description :

A complete update of the highly acclaimed handbook with data on all neurotransmitters and the majority of neuromodulators. The coverage is now even more comprehensive, with 15% more entries on neuropeptides, "classic" neurotransmitters and related substances in a clear, alphabetical format. The methodological section has been expanded by 50% and now includes color figures, plus new chapters on genomics, proteomics, databases, microarrays, MALDI-TOF, neutrophins, FGF, endocannabinoids and neuroimaging. The text provides clearly structured information on the biosynthesis and degradation, localization, receptors, signal transduction pathways, and biological effects in the central nervous system, with all substances uniformly treated for an easy comparison of data. Furthermore, introductory chapters on receptors, transporters, and the blood-brain barrier make this an indispensable tool for researchers, teachers, and advanced students, as well as a must-have for every neuroscientist.

Handbook of Basal Ganglia Structure and Function Book
Score: 5
From 1 Ratings

Handbook of Basal Ganglia Structure and Function


  • Author : Heinz Steiner
  • Publisher : Academic Press
  • Release Date : 2010-03-17
  • Genre: Medical
  • Pages : 704
  • ISBN 10 : 9780080912158

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Handbook of Basal Ganglia Structure and Function Book Description :

The Basal Ganglia comprise a group of forebrain nuclei that are interconnected with the cerebral cortex, thalamus and brainstem. Basal ganglia circuits are involved in various functions, including motor control and learning, sensorimotor integration, reward and cognition. The importance of these nuclei for normal brain function and behavior is emphasized by the numerous and diverse disorders associated with basal ganglia dysfunction, including Parkinson’s disease, Tourette’s syndrome, Huntington’s disease, obsessive-compulsive disorder, dystonia, and psychostimulant addiction. The Handbook of Basal Ganglia provides a comprehensive overview of the structural and functional organization of the basal ganglia, with special emphasis on the progress achieved over the last 10-15 years. Organized in six parts, the volume describes the general anatomical organization and provides a review of the evolution of the basal ganglia, followed by detailed accounts of recent advances in anatomy, cellular/molecular, and cellular/physiological mechanisms, and our understanding of the behavioral and clinical aspects of basal ganglia function and dysfunction. Synthesizes widely dispersed information on the behavioral neurobiology of the basal ganglia, including advances in the understanding of anatomy, cell-molecular and cell-physiological mechanisms, and behavioral/clinical aspects of function and dysfunction Features a truly international cast of the preeminent researchers in the field Fully explores the clinically relevant impact of the basal ganglia on various psychiatric and neurological diseases

Handbook of Sample Preparation Book

Handbook of Sample Preparation


  • Author : Janusz Pawliszyn
  • Publisher : Wiley-Blackwell
  • Release Date : 2011-03-17
  • Genre: Science
  • Pages : 480
  • ISBN 10 : 0813823625

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Handbook of Sample Preparation Book Description :

Discover new keys to solving analytical problems using the Latest sample preparation methods Commonly viewed of as a routine task rather than as an integral component in the analytical process, sample preparation has long been undervalued as a science and underdeveloped as a technology. In an effort to reverse this trend, Handbook of Sample Preparation shows why sample preparation deserves closer scientific scrutiny, and makes a compelling case for colleges and professional laboratories to devote more resources to promote the benefits of its correct application. Handbook of Sample Preparation includes: A solid overview of standard sampling methodologies and their analytical capabilities An introduction of non-traditional sampling technologies, which address the need for solvent-free alternatives, automation, and miniaturization A discussion of the analytical shift toward performing sampling on-site, rather than in the laboratory An examination of various extraction technologies and their applications for different types of matrices A look at how to take advantage of new sampling strategies to streamline laboratory procedures, reduce research costs, and increase overall productivity An excellent primer on the fundamentals of extraction as well as a sound guide on the latest technological upgrades influencing current sampling techniques, this versatile text serves as an important and accessible tool for both students and seasoned practitioners as they seek new avenues for improving the accuracy of their analyses.

Handbook of Cannabis Book

Handbook of Cannabis


  • Author : Roger Pertwee
  • Publisher : OUP Oxford
  • Release Date : 2014-08-21
  • Genre: Medical
  • Pages : 632
  • ISBN 10 : 9780191639708

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Handbook of Cannabis Book Description :

Truly global in scope and with contributions from leading researchers around the world, The Handbook of Cannabis is the definitive resource on this fascinating drug. Combining scientific perspectives and clinical applications, it covers a vast array of topics, from why over the centuries cannabis has been used as a medicine, through the regulations facing those wishing to self-administer cannabis or provide cannabis-based medicines, to the chemical structure of its many constituents and the rapidly growing group of synthetic cannabinoids that are currently being used for 'legal highs'. With each chapter written by a group of one or more internationally recognised subject experts, it provides academics and researchers with authoritative scientific material on the main pharmacological actions and their effects, as well as their pharmacokinetics, metabolism, and forensic detection. In addition it also examines the complex morphology, cultivation, harvesting, and processing of cannabis and the ways in which the plant's chemical composition can be controlled. As well as offering a raft of scientific information there is extensive coverage of cannabinoid-based medicines. Helping readers to identify and evaluate their benefits, chapters explore pharmacological actions and the effects that seem to underlie approved therapeutic uses, how they are currently used to treat certain disorders, and the ever-growing number of wide-ranging potential clinical applications. There is also coverage of both the legal and illegal sources of cannabis, including 'coffee shops' and 'cannabis dispensaries'. The complex issue of 'recreational cannabis' is also tackled. The sought-after and adverse psychological and non-psychological effects are described and discussions are included on how some adverse effects can be lessened by at least one constituent of cannabis, and that it might be possible to reduce the harm that cannabis does to some by changing current regulatory policies. The Handbook

Biomedical Photonics Handbook Book
Score: 5
From 1 Ratings

Biomedical Photonics Handbook


  • Author : Tuan Vo-Dinh
  • Publisher : CRC Press
  • Release Date : 2003-03-26
  • Genre: Medical
  • Pages : 1872
  • ISBN 10 : 0203008995

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Biomedical Photonics Handbook Book Description :

A wide variety of biomedical photonic technologies have been developed recently for clinical monitoring of early disease states; molecular diagnostics and imaging of physiological parameters; molecular and genetic biomarkers; and detection of the presence of pathological organisms or biochemical species of clinical importance. However, available information on this rapidly growing field is fragmented among a variety of journals and specialized books. Now researchers and medical practitioners have an authoritative and comprehensive source for the latest research and applications in biomedical photonics. Over 150 leading scientists, engineers, and physicians discuss state-of-the-art instrumentation, methods, and protocols in the Biomedical Photonics Handbook. Editor-in-Chief Tuan Vo-Dinh and an advisory board of distinguished scientists and medical experts ensure that each of the 65 chapters represents the latest and most accurate information currently available.

Biomedical Engineering Handbook 2 Book
Score: 4
From 1 Ratings

Biomedical Engineering Handbook 2


  • Author : Joseph D. Bronzino
  • Publisher : Springer Science & Business Media
  • Release Date : 2000-02-15
  • Genre: Technology & Engineering
  • Pages :
  • ISBN 10 : 354066808X

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Biomedical Engineering Handbook 2 Book Description :

Handbook of Forgiveness Book

Handbook of Forgiveness


  • Author : Everett L. Worthington, Jr.
  • Publisher : Routledge
  • Release Date : 2007-12-11
  • Genre: Psychology
  • Pages : 624
  • ISBN 10 : 9781135410957

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Handbook of Forgiveness Book Description :

There is a need in both public and professional sectors for a deeper, and more complete understanding of forgiveness, as we are - in the author's own words - "on the threshold of an age of forgiveness and reconciliation." And yet despite continued interest and development in the field, researchers, clinicians, practitioners, and academics have long been without a comprehensive resource on which to base their work. The Handbook of Forgiveness summarizes the state of the science in the research, practice, and teaching of forgiveness. Chapters approach forgiveness and reconciliation from a variety of perspectives, drawing on related work in fields such as biology, personality, social psychology, clinical psychology, developmental psychology, philosophy, neuroscience, and international/political implications. The Handbook provides comprehensive treatments of the topic, integrating theoretical considerations, methodological discussions, and practical interventions strategies in order to appeal to researchers, clinicians, and practitioners. This volume is the most up-to-date and authoritative resource on the understanding of the science of forgiveness. The Handbook of Forgiveness has been chosen as a Book of Distinction by Templeton Press.