Handbook of Neuroemergency Clinical Trials Book

Handbook of Neuroemergency Clinical Trials


  • Author : Brett E. Skolnick
  • Publisher : Academic Press
  • Release Date : 2017-11-13
  • Genre: Science
  • Pages : 400
  • ISBN 10 : 9780128041017

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Handbook of Neuroemergency Clinical Trials Excerpt :

Handbook of Neuroemergency Clinical Trials, Second Edition, focuses on the practice of clinical trials in acute neuroscience populations, or what have been called neuroemergencies. Neuroemergencies are complex, life-threatening diseases and disorders, often with devastating consequences, including death or disability. The overall costs are staggering in terms of annual incidence and costs associated with treatment and survival, yet despite their significance as public health issues, there are few drugs and devices available for definitive treatment. The book focuses on novel therapies and the unique challenges their intended targets pose for the design and analysis of clinical trials. This volume provides neurologists, neuroscientists, and drug developers with a more complete understanding of the scientific and medical issues of relevance in designing and initiating clinical development plans for novel drugs intended for acute neuroscience populations. The editors provide the best understanding of the pitfalls associated with acute CNS drug development and the best information on how to approach and solve issues that have plagued drug development. Presents a comprehensive overview on clinical trials and drug development challenges in acute neuroscience populations Provides neurologists, neuroscientists and drug developers with a complete understanding of scientific and medical issues related to designing clinical trials Edited by leaders in the field who have designed and managed over 50 neuroemergency clinical trials

Behavioral Clinical Trials for Chronic Diseases Book

Behavioral Clinical Trials for Chronic Diseases


  • Author : Lynda H. Powell
  • Publisher : Springer Nature
  • Release Date : 2021
  • Genre: Alternative medicine
  • Pages : 324
  • ISBN 10 : 9783030393304

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Behavioral Clinical Trials for Chronic Diseases Excerpt :

This is the first comprehensive guide to the design of behavioral randomized clinical trials (RCT) for chronic diseases. It includes the scientific foundations for behavioral trial methods, problems that have been encountered in past behavioral trials, advances in design that have evolved, and promising trends and opportunities for the future. The value of this book lies in its potential to foster an ability to speak the language of medicine through the conduct of high-quality behavioral clinical trials that match the rigor commonly seen in double-blind drug trials. It is relevant for testing any treatment aimed at improving a behavioral, social, psychosocial, environmental, or policy-level risk factor for a chronic disease including, for example, obesity, sedentary behavior, adherence to treatment, psychosocial stress, food deserts, and fragmented care. Outcomes of interest are those that are of clinical significance in the treatment of chronic diseases, including standard risk factors such as cholesterol, blood pressure, and glucose, and clinical outcomes such as hospitalizations, functional limitations, excess morbidity, quality of life, and mortality. This link between behavior and chronic disease requires innovative clinical trial methods not only from the behavioral sciences but also from medicine, epidemiology, and biostatistics. This integration does not exist in any current book, or in any training program, in either the behavioral sciences or medicine.

Handbook of Neurosurgery  Neurology  and Spinal Medicine for Nurses and Advanced Practice Health Professionals Book

Handbook of Neurosurgery Neurology and Spinal Medicine for Nurses and Advanced Practice Health Professionals


  • Author : Michael Wang
  • Publisher : Routledge
  • Release Date : 2017-12-15
  • Genre: Medical
  • Pages : 792
  • ISBN 10 : 9781498719445

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Handbook of Neurosurgery Neurology and Spinal Medicine for Nurses and Advanced Practice Health Professionals Excerpt :

This practical handbook allows nurses, advanced practice nurses, physician assistants, and allied health professionals practicing in the fields of neurosurgery, neurology, and spinal care to quickly review essentials while in the work environment. It emphasizes procedural steps and critical elements in patient management, including intensive care, the neurological examination, differential diagnoses, and pain management. Written by a multidisciplinary team of experts, the handbook is expected to become a well-worn companion and essential aid to the busy practitioner.

Neurosurgical Ethics in Practice  Value based Medicine Book

Neurosurgical Ethics in Practice Value based Medicine


  • Author : Ahmed Ammar
  • Publisher : Springer
  • Release Date : 2014-06-26
  • Genre: Medical
  • Pages : 286
  • ISBN 10 : 9783642549809

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Neurosurgical Ethics in Practice Value based Medicine Excerpt :

Good neurosurgical practice is based not only on evidence, skills, and modern equipment, but also on good values. This book is the first to discuss specifically the ethical issues that arise during the daily practice of neurosurgery. It is divided into three parts addressing patients’ rights, ethical issues relating to the working environment, and wider societal aspects such as dealings of neurosurgeons with the legal system, the media, and companies. The authors are well-established neurosurgeons who present the ethical problems that they have encountered during their careers and explain what they have learned in confronting these problems. In all, more than 50 neurosurgical cases drawn from real life are reported and discussed from an ethical point of view. This book will be especially informative for young neurosurgeons and will provide all who work in this very special field with a road map on how to avoid violations of medical ethics in neurosurgical practice.

Atlas of Uncommon Pain Syndromes E Book Book

Atlas of Uncommon Pain Syndromes E Book


  • Author : Steven D. Waldman
  • Publisher : Elsevier Health Sciences
  • Release Date : 2019-09-19
  • Genre: Medical
  • Pages : 488
  • ISBN 10 : 9780323640787

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Atlas of Uncommon Pain Syndromes E Book Excerpt :

Covering the many relatively uncommon pain conditions that are often misdiagnosed, this one-of-a-kind visual resource clearly presents the extensive knowledge and experience of world-renowned pain expert Steven D. Waldman, MD, JD. Atlas of Uncommon Pain Syndromes, 4th Edition, first and foremost helps you make a correct diagnosis – a critical step in managing patients in chronic pain. Hundreds of high-quality illustrations, as well as x-rays, ultrasound, CTs, and MRIs, help you confirm your diagnoses with confidence. Offers head-to-toe coverage – 135 conditions in all – providing concise, easy-to-read chapters for each condition. Dr. Waldman’s practical guidance is designed to help you make the correct diagnosis of uncommon pain syndromes, even the signs and symptoms don’t quite fit. Explains each pain syndrome using a consistent, easy-to-follow format: an ICD-10 CM code for billing purposes, followed by a brief description of the signs and symptoms, laboratory and radiographic testing, differential diagnosis, available treatment options, and clinical pearls. Features updated chapters throughout, as well as 12 new chapters covering Hemicrania Continua, Acute Calcific Prevertebral Tendinitis, Sternohyoid Syndrome Snapping Scapula Syndrome, Erythromelagia, Foix-Alajouanine Syndrome, Lumbar Paraspinous Muscle Compartment Syndrome, Clunealgia, Nutcracker Syndrome, Paroxysmal Extreme Pain Disorder, Iliopsoas Tendon Rupture, and Snapping Pes Anserinus Syndrome Provides practitioners and trainees in pain medicine, anesthesiology, neurology, psychiatry, physical medicine and rehabilitation, primary care, and more with a firm foundation in the diagnosis of uncommon pain in daily practice.

Atlas of Common Pain Syndromes E Book Book

Atlas of Common Pain Syndromes E Book


  • Author : Steven D. Waldman
  • Publisher : Elsevier Health Sciences
  • Release Date : 2011-06-09
  • Genre: Medical
  • Pages : 408
  • ISBN 10 : 9781455733552

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Atlas of Common Pain Syndromes E Book Excerpt :

Noted pain authority Dr. Steven Waldman returns with a new edition of Atlas of Common Pain Syndromes. Delivering complete, concise, step-by-step visual guidance, this innovative, popular atlas equips you to effectively diagnose and manage pain syndromes commonly encountered in any clinical practice. Clearly labeled, vivid illustrations depict the physical symptoms and anatomy of each pain site, and diagnostic images demonstrate key findings from MRI, CT, and conventional radiography. With an easy-to use, templated format, you’ll have Dr. Waldman’s preferred approaches right at your fingertips. Accurately diagnose and treat common pain syndromes by following a step-by-step approach that progresses from signs and symptoms through physical findings, laboratory and radiographic testing, treatment options, clinical pearls, and diagnostic codes. Practice with confidence by consulting with Steven D. Waldman, MD - author of numerous groundbreaking pain management references - as well as a team of leading international authorities. Quickly and easily find the information you need thanks to highly templated chapters that explore signs and symptoms, physical findings, laboratory and radiographic testing, treatment options, clinical pearls, and diagnostic codes for each pain syndrome. Ensure proper reimbursement with comprehensive coverage of insurance coding information. Avoid potential pitfalls in diagnosis and treatment by referring to "Side Effects and Complications" sections in each chapter. See, identify, and diagnose patients’ issues with help from clinically relevant illustrations that connect pain syndromes to clearly labeled anatomic illustrations. Effectively apply the latest techniques and approaches with 29 new chapters covering subarachnoid hemorrhage, adhesive capsulitis, iliopectineal bursitis, discitis, and more!

Neurotrauma Book

Neurotrauma


  • Author : Kevin Wang
  • Publisher : Oxford University Press
  • Release Date : 2018-11-07
  • Genre: Medical
  • Pages : 624
  • ISBN 10 : 9780190279455

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Neurotrauma Excerpt :

Neurotrauma: A Comprehensive Textbook on Traumatic Brain Injury and Spinal Cord Injury aims to bring together the latest clinical practice and research in the filed of two forms of trauma to the central nervous system: namely traumatic brain injury (TBI) and spinal cord injury (SCI). Nationally, more 1.9 million Americans sustain a traumatic brain injury annually. In parallel, there are an estimate of 12,000 new cases of SCI in the United States annually. In addition, approximately 1.2 million people live with paralysis due to SCI. In recent years, dramatic advancements in the field have resulted in much improved outcomes for patients and higher standards of care. This volume details the latest research and clinical practice in the treatment of neurotrauma, in a comprehensive but easy-to-follow format. Neurotrauma is a valuable resource for any clinician involved in caring for TBI and SCI patients, clinical research professionals, researchers, medical and graduate students, and nurse specialists.

Diseases of the Brain  Head and Neck  Spine 2020   2023 Book

Diseases of the Brain Head and Neck Spine 2020 2023


  • Author : Juerg Hodler
  • Publisher : Springer Nature
  • Release Date : 2020-02-14
  • Genre: Medical
  • Pages : 254
  • ISBN 10 : 9783030384906

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Diseases of the Brain Head and Neck Spine 2020 2023 Excerpt :

This open access book offers an essential overview of brain, head and neck, and spine imaging. Over the last few years, there have been considerable advances in this area, driven by both clinical and technological developments. Written by leading international experts and teachers, the chapters are disease-oriented and cover all relevant imaging modalities, with a focus on magnetic resonance imaging and computed tomography. The book also includes a synopsis of pediatric imaging. IDKD books are rewritten (not merely updated) every four years, which means they offer a comprehensive review of the state-of-the-art in imaging. The book is clearly structured and features learning objectives, abstracts, subheadings, tables and take-home points, supported by design elements to help readers navigate the text. It will particularly appeal to general radiologists, radiology residents, and interventional radiologists who want to update their diagnostic expertise, as well as clinicians from other specialties who are interested in imaging for their patient care.

Small Animal Neurological Emergencies Book

Small Animal Neurological Emergencies


  • Author : Simon Platt
  • Publisher : CRC Press
  • Release Date : 2012-03-15
  • Genre: Medical
  • Pages : 672
  • ISBN 10 : 9781482261714

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Small Animal Neurological Emergencies Excerpt :

This new book deals systematically with the assessment and treatment of small animal neurological patients in light of latest research findings and greatly improved imaging techniques. The authors first discuss step-wise neurological and systemic approaches to common emergency cases-examination, critical care and rapid assessment-based on presentin

Toxicology of Organophosphate and Carbamate Compounds Book

Toxicology of Organophosphate and Carbamate Compounds


  • Author : Ramesh C. Gupta
  • Publisher : Academic Press
  • Release Date : 2011-04-28
  • Genre: Science
  • Pages : 768
  • ISBN 10 : 0080543103

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Toxicology of Organophosphate and Carbamate Compounds Excerpt :

This text/reference book provides the most comprehensive coverage of anticholinesterase compounds (Organophosphates and Carbamates), which constitute the largest number of chemicals that are primarily used as insecticides in agriculture, industry, and around the home/garden. Some OPs (nerve agents) have been used in chemical warfare and terrorist attacks, while some OPs and CMs have been recommended as therapeutic agents in human medicine as well as in veterinary medicine. Many chemicals of both classes are extremely toxic and lack selectivity, thus their inadvertent/accidental use continues to pose a threat to human and animal health, aquatic systems and wildlife. These anticholinesterase agents produce a variety of toxicological effects in target and nontarget organs. In light of this complexicity, this multi-authored book is written by the well known scientists from many countries. The book is organized into nine sections, with a total of 49 chapters, to provide in-depth knowledge on various aspects of OP and CM compounds, including their use, classification, mechanism-based toxicity, and prophylactic and therapeutic measurements. Several chapters are written with special emphasis to cover timely topics, such as chemical warfare agents, physiologically-based pharmacokinetic modeling, structure and function of cholinesterases, paraoxonase, carboxylesterases; developmental neurotoxicity, the intermediate syndrome, oxidative stress, endocrine disruption, and DNA damage/gene expression and carcinogenesis. Section-VI with 5 chapters is specifically devoted to risk assessment, and safety and regulatory guidelines for pesticides. Describes everything you need to know about Organophosphates and Carbamates Extensively covers pesticides, nerve agents, therapeutic drugs, and flame retardants Describes epidemiology of the world's major disasters involving Organophosphates and Carbamates Covers animal, human, aquatic, and wildlife toxicity of Anticholinesterases Insights into

Neurological Emergencies Book

Neurological Emergencies


  • Author : S.D. Shorvon
  • Publisher : Butterworth-Heinemann
  • Release Date : 2013-10-22
  • Genre: Health & Fitness
  • Pages : 120
  • ISBN 10 : 9781483182681

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Neurological Emergencies Excerpt :

Neurological Emergencies presents a comprehensive guide on the initial assessment and early treatment of patients with neurological emergencies. It discusses the diagnosis, emergency investigations, and handling of coma patients. It addresses the management of focal supratentorial lesion. Some of the topics covered in the book are the diffuse neurological or systemic disturbance; emergency resuscitation; diagnosis and treatment of transtentorial herniation; diagnosis and treatment of acute viral encephalitis; raised intracranial pressure; diagnosis and treatment of non-viral infective encephalitis; viral meningitis; meningovascular syphilis; diagnosis and treatment of cerebral abscess; diagnosis and treatment of intracranial subdural empyema; and diagnosis and treatment of cerebral venous thrombosis. The diagnosis and treatment ofstroke is fully covered. An in-depth account of the difference between haemorrhage and infarction is provided. The diagnosis of subarachnoid haemorrhage is completely presented. A chapter is devoted to the prevention of more cranial bleeding.

Emergency Neurology Book

Emergency Neurology


  • Author : Karen L. Roos
  • Publisher : Springer Nature
  • Release Date : 2021-08-08
  • Genre: Medical
  • Pages : 412
  • ISBN 10 : 9783030757786

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Emergency Neurology Excerpt :

This book is an invaluable resource for the diagnosis and management of neurological illnesses in the emergency setting. It emphasizes the quality of prognosis to be contingent on the prompt management of these illnesses. Emergency Neurology, Second Edition follows the exemplary format of the previous edition, with comprehensive chapters on every neurological emergency, including stroke, headache, back pain, dizziness, vertigo, syncope, visual loss, diplopia, facial nerve palsy, weakness, altered mental status, coma, meningitis and encephalitis, seizures, and spinal cord disorders. Chapters emphasize the clinical presentation, diagnostic studies and management, and include high-quality images and tables that are invaluable for rapid diagnosis and therapy. Building off its predecessor's success, Emergency Neurology, Second Edition is an excellent reference for neurologists, emergency room physicians, internists, neurology residents, emergency medicine residents, and internal medicine residents.