Handbook of Pharmaceutical Analysis by HPLC Book

Handbook of Pharmaceutical Analysis by HPLC


  • Author : Satinder Ahuja
  • Publisher : Elsevier
  • Release Date : 2005-02-09
  • Genre: Medical
  • Pages : 600
  • ISBN 10 : 0080455182

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Handbook of Pharmaceutical Analysis by HPLC Excerpt :

High pressure liquid chromatography–frequently called high performance liquid chromatography (HPLC or, LC) is the premier analytical technique in pharmaceutical analysis and is predominantly used in the pharmaceutical industry. Written by selected experts in their respective fields, the Handbook of Pharmaceutical Analysis by HPLC Volume 6, provides a complete yet concise reference guide for utilizing the versatility of HPLC in drug development and quality control. Highlighting novel approaches in HPLC and the latest developments in hyphenated techniques, the book captures the essence of major pharmaceutical applications (assays, stability testing, impurity testing, dissolution testing, cleaning validation, high-throughput screening). A complete reference guide to HPLC Describes best practices in HPLC and offers 'tricks of the trade' in HPLC operation and method development Reviews key HPLC pharmaceutical applications and highlights currents trends in HPLC ancillary techniques, sample preparations, and data handling

Handbook of Modern Pharmaceutical Analysis Book

Handbook of Modern Pharmaceutical Analysis


  • Author : Satinder Ahuja
  • Publisher : Academic Press
  • Release Date : 2010-11-11
  • Genre: Medical
  • Pages : 598
  • ISBN 10 : 0123759811

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Handbook of Modern Pharmaceutical Analysis Excerpt :

Handbook of Modern Pharmaceutical Analysis, Second Edition, synthesizes the complex research and recent changes in the field, while covering the techniques and technology required for today's laboratories. The work integrates strategy, case studies, methodologies, and implications of new regulatory structures, providing complete coverage of quality assurance from the point of discovery to the point of use. Treats pharmaceutical analysis (PA) as an integral partner to the drug development process rather than as a service to it Covers method development, validation, selection, testing, modeling, and simulation studies combined with advanced exploration of assays, impurity testing, biomolecules, and chiral separations Features detailed coverage of QA, ethics, and regulatory guidance (quality by design, good manufacturing practice), as well as high-tech methodologies and technologies from "lab-on-a-chip" to LC-MS, LC-NMR, and LC-NMR-MS

Handbook of HPLC Book

Handbook of HPLC


  • Author : Danilo Corradini
  • Publisher : CRC Press
  • Release Date : 2016-04-19
  • Genre: Science
  • Pages : 715
  • ISBN 10 : 9781420016949

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Handbook of HPLC Excerpt :

High performance liquid chromatography (HPLC) is one of the most widespread analytical and preparative scale separation techniques used for both scientific investigations and industrial and biomedical analysis. Now in its second edition, this revised and updated version of the Handbook of HPLC examines the new advances made in this field since the

Handbook of HPLC Book
Score: 3
From 5 Ratings

Handbook of HPLC


  • Author : Danilo Corradini
  • Publisher : CRC Press
  • Release Date : 2011-01-03
  • Genre: Science
  • Pages : 1008
  • ISBN 10 : 0203909755

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Handbook of HPLC Excerpt :

Delineating its usage in separation, purification and detection processes across a variety of disciplines, from industry to applied research, this work discusses the principles, techniques and instrumentation involving HPLC within a detailed framework. Over 100 tables present previously scattered experimental data.

Handbook of Analytical Quality by Design Book

Handbook of Analytical Quality by Design


  • Author : Sarwar Beg
  • Publisher : Academic Press
  • Release Date : 2021-01-09
  • Genre: Business & Economics
  • Pages : 222
  • ISBN 10 : 9780128203330

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Handbook of Analytical Quality by Design Excerpt :

Handbook of Analytical Quality by Design addresses the steps involved in analytical method development and validation in an effort to avoid quality crises in later stages. The AQbD approach significantly enhances method performance and robustness which are crucial during inter-laboratory studies and also affect the analytical lifecycle of the developed method. Sections cover sample preparation problems and the usefulness of the QbD concept involving Quality Risk Management (QRM), Design of Experiments (DoE) and Multivariate (MVT) Statistical Approaches to solve by optimizing the developed method, along with validation for different techniques like HPLC, UPLC, UFLC, LC-MS and electrophoresis. This will be an ideal resource for graduate students and professionals working in the pharmaceutical industry, analytical chemistry, regulatory agencies, and those in related academic fields. Concise language for easy understanding of the novel and holistic concept Covers key aspects of analytical development and validation Provides a robust, flexible, operable range for an analytical method with greater excellence and regulatory compliance

Handbook of Pharmaceutical Analysis Book
Score: 3
From 1 Ratings

Handbook of Pharmaceutical Analysis


  • Author : Lena Ohannesian
  • Publisher : CRC Press
  • Release Date : 2001-11-09
  • Genre: Medical
  • Pages : 608
  • ISBN 10 : 9780824741945

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Handbook of Pharmaceutical Analysis Excerpt :

Exploring the analysis of pharmaceuticals, including polymorphic forms, this book discusses regulatory requirements in pharmaceutical product development and pharmaceutical testing. It covers methods of drug separation and procedures such as capillary electrophoresis for chromatographic separation of molecules. Additional topics include drug formulation analysis using vibrational and magnetic resonance spectroscopy and identification of drug metabolites and decomposition products using such techniques as mass spectrometry. The book provides more than 300 tables, equations, drawings, and photographs, and convenient, easy-to-use indices, facilitating quick access to each topic.

A Practical Handbook of Preparative HPLC Book

A Practical Handbook of Preparative HPLC


  • Author : Donald A Wellings
  • Publisher : Elsevier
  • Release Date : 2011-04-18
  • Genre: Technology & Engineering
  • Pages : 176
  • ISBN 10 : 0080458858

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A Practical Handbook of Preparative HPLC Excerpt :

This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA. This book... •Provides practical, hands-on advice based on years of experience •Will help ensure optimal design, equipment and separation results for your particular task •Presents system layouts from laboratory to process scale •Will help you to devise or improve record-keeping and documentation systems ·Provides practical, hands-on advice based on years of experience ·Will help ensure optimal design, equipment and separation results for your particular task ·Presents system layouts from laboratory to process scale ·Will help you to devise or improve record-keeping and documentation systems

Handbook of Analysis of Oligonucleotides and Related Products Book

Handbook of Analysis of Oligonucleotides and Related Products


  • Author : Jose V. Bonilla
  • Publisher : CRC Press
  • Release Date : 2011-02-23
  • Genre: Medical
  • Pages : 511
  • ISBN 10 : 9781439819937

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Handbook of Analysis of Oligonucleotides and Related Products Excerpt :

Oligonucleotides represent one of the most significant pharmaceutical breakthroughs in recent years, showing great promise as diagnostic and therapeutic agents for malignant tumors, cardiovascular disease, diabetes, viral infections, and many other degenerative disorders. The Handbook of Analysis of Oligonucleotides and Related Products is an essential reference manual on the practical application of modern and emerging analytical techniques for the analysis of this unique class of compounds. A strong collaboration among thirty leading analytical scientists from around the world, the book provides readers with a comprehensive overview of the most commonly used analytical techniques and their advantages and limitations in assuring the identity, purity, quality, and strength of an oligonucleotide intended for therapeutic use. Topics discussed include: Strategies for enzymatic or chemical degradation of chemically modified oligonucleotides toward mass spectrometric sequencing Purity analysis by chromatographic or electrophoretic methods, including RP-HPLC, AX-HPLC, HILIC, SEC, and CGE Characterization of sequence-related impurities in oligonucleotides by mass spectrometry and chromatography Structure elucidation by spectroscopic methods (IR, NMR, MS) as well as base composition and thermal melt analysis (Tm) Approaches for the accurate determination of molar extinction coefficient of oligonucleotides Accurate determination of assay values Assessment of the overall quality of oligonucleotides, including microbial analysis and determination of residual solvents and heavy metals Strategies for determining the chemical stability of oligonucleotides The use of hybridization techniques for supporting pharmacokinetics and drug metabolism studies in preclinical and clinical development Guidance for the presentation of relevant analytical information towards meeting current regulatory expectations for oligonucleotide therapeutics This resource provides a practical guide for app

Modern HPLC for Practicing Scientists Book

Modern HPLC for Practicing Scientists


  • Author : Michael W. Dong
  • Publisher : John Wiley & Sons
  • Release Date : 2016-04-06
  • Genre: Science
  • Pages : 304
  • ISBN 10 : 9781119293606

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Modern HPLC for Practicing Scientists Excerpt :

A comprehesive yet concise guide to Modern HPLC Written for practitioners by a practitioner, Modern HPLC for Practicing Scientists is a concise text which presents the most important High-Performance Liquid Chromatography (HPLC) fundamentals, applications, and developments. It describes basic theory and terminology for the novice, and reviews relevant concepts, best practices, and modern trends for the experienced practitioner. Moreover, the book serves well as an updated reference guide for busy laboratory analysts and researchers. Topics covered include: HPLC operation Method development Maintenance and troubleshooting Modern trends in HPLC such as quick-turnaround and "greener" methods Regulatory aspects While broad in scope, this book focuses particularly on reversed-phase HPLC, the most common separation mode, and on applications for the pharmaceutical industry, the largest user segment. Accessible to both novice and intermedate HPLC users, information is delivered in a straightforward manner illustrated with an abundance of diagrams, chromatograms, tables, and case studies, and supported with selected key references and Web resources. With intuitive explanations and clear figures, Modern HPLC for Practicing Scientists is an essential resource for practitioners of all levels who need to understand and utilize this versatile analytical technology.

HPLC Method Development and Validation in Pharmaceutical Analysis Book

HPLC Method Development and Validation in Pharmaceutical Analysis


  • Author : Ghulam Shabir
  • Publisher : LAP Lambert Academic Publishing
  • Release Date : 2013-01
  • Genre: Uncategoriezed
  • Pages : 492
  • ISBN 10 : 3659321206

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HPLC Method Development and Validation in Pharmaceutical Analysis Excerpt :

This handbook is concerned with new chromatographic method development and validation using novel systematic approaches for pharmaceutical compounds. The first stage of the research was to study how method development and validation are typically carried out at present and to formulate this into a simple step-by-step approach. Such a template and protocol was not only used as the foundation of this research programme but could also serve as a simple systematic guide for other practitioners in the pharmaceutical industry. Furthermore, it was recognised that this protocol should satisfy the requirements of the major regulatory agencies. The second stage of this research involved evaluation and application of the above validation approach to new methods that were developed for a diverse range of analytes using HPLC, LC-MS and GC. In essence, the critical review of the requirements for method validation for various agencies and the subsequent preparation of single guidelines on how to go about method validation have had a significant impact on analytical practitioners worldwide.

Handbook of Stability Testing in Pharmaceutical Development Book
Score: 3
From 3 Ratings

Handbook of Stability Testing in Pharmaceutical Development


  • Author : Kim Huynh-Ba
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-11-16
  • Genre: Medical
  • Pages : 389
  • ISBN 10 : 9780387856278

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Handbook of Stability Testing in Pharmaceutical Development Excerpt :

This handbook is the first to cover all aspects of stability testing in pharmaceutical development. Written by a group of international experts, the book presents a scientific understanding of regulations and balances methodologies and best practices.

HPLC Methods for Recently Approved Pharmaceuticals Book
Score: 5
From 1 Ratings

HPLC Methods for Recently Approved Pharmaceuticals


  • Author : George Lunn
  • Publisher : John Wiley & Sons
  • Release Date : 2005-05-06
  • Genre: Science
  • Pages : 640
  • ISBN 10 : 9780471711674

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HPLC Methods for Recently Approved Pharmaceuticals Excerpt :

An indispensable resource for busy researchers Your time is valuable-too valuable to spend hunting through thetechnical literature in search of the right HPLC assay techniquesfor your projects. With HPLC Methods for Recently ApprovedPharmaceuticals, you'll quickly identify and replicate the idealprocedures for your project needs, without having to refer tooriginal source publications. More of your time can then be spentin the lab, not the library. Covering the relevant world literature through 2003, this bookpicks up where Dr. Lunn's acclaimed HPLC Methods for PharmaceuticalAnalysis left off. It arms you with established HPLC assaytechniques for hundreds of newly approved drugs, as well as drugsfor which assay methods were only recently developed. Combiningdetailed descriptions of procedures with specially annotatedreferences, this practical handbook gives you: * HPLC methods for 390 commonly prescribed pharmaceuticalcompounds * Various procedures for each drug listed together-making it easyto mix and match for customized approaches * Methods for drugs in biological fluids and for bulk andformulated drugs * Chemical structures, molecular weights and formulas, and CASRegistry Numbers * Cross-references to The Merck Index * Retention times of other drugs that can be assayed using the samemethods

High Performance Liquid Chromatography Book

High Performance Liquid Chromatography


  • Author : Omar Al Sayed Omar
  • Publisher : Walter de Gruyter GmbH & Co KG
  • Release Date : 2022-02-21
  • Genre: Science
  • Pages : 322
  • ISBN 10 : 9783110529456

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High Performance Liquid Chromatography Excerpt :

The book provides an indispensable guide on how to use HPLC in pharmaceutical analysis and drug control. Following a hands-on approach, the authors give practical advices how to prepare stationary and mobile phases, choose a suitable detector and set up an HPLC analysis. The publication gives insight into the key pharmaceutical applications of HPLC and the latest requirements of the major regulatory agencies.

Handbook of Derivatization Reactions for HPLC  Book   CD Set Book

Handbook of Derivatization Reactions for HPLC Book CD Set


  • Author : George Lunn
  • Publisher : Wiley-Interscience
  • Release Date : 1998-11-12
  • Genre: Science
  • Pages : 1795
  • ISBN 10 : STANFORD:36105029289472

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Handbook of Derivatization Reactions for HPLC Book CD Set Excerpt :

Thousands of derivatization procedures for HPLC and CE—an essential tool for today's analytical chemist. This valuable reference offers fast and convenient access to derivatization reactions for both HPLC and capillary electrophoresis (CE). Covering a wide variety of compounds from pharmaceutical drugs and biological products to industrial contaminants, it is organized first by functional group and then by individual reagents. Techniques for each functional group are described in sufficient detail that the researcher can replicate procedures without reference to the original publications—saving hours of tedious library research. And because detailed procedures for the same reagent are listed together, it is easy to combine features of different methods and tailor them to fit specific individual requirements. Also available on CD-ROM, Handbook of Derivatization Reactions for HPLC contains fully abstracted and evaluated procedures from more than 1,900 papers, with descriptions of hundreds of reagents. A further 3,000 papers are referenced in bibliographies that are clearly annotated to help analysts identify those sources likely to be most useful. This important new resource will be welcomed by chemists working in pharmaceutical, biomedical, and environmental analysis. Also available on CD-ROM System requirements . . . IBM-compatible PC 486 or better and Windows(r) 3.0 or higher, or Macintosh 68030 processor and System 7 or higher CD-ROM drive and 8 MB RAM minimum 5 MB free hard disk space minimum, 30 MB recommended for full installation.