Handbook of Process Chromatography Book

Handbook of Process Chromatography


  • Author : Gunter Jagschies
  • Publisher : Elsevier
  • Release Date : 2007-12-08
  • Genre: Science
  • Pages : 382
  • ISBN 10 : 0080554512

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Handbook of Process Chromatography Book Description :

This book will update the original edition published in 1997. Since the publication of the first edition, the biotechnology and biologics industries have gained extensive knowledge and experience in downstream processing using chromatography and other technologies associated with recovery and purification unit operations. This book will tie that experience together for the next generation of readers. Updates include: - sources and productivity - types of products made today - experiences in clinical and licensed products - economics - current status of validation - illustrations and tables - automated column packing - automated systems New topics include: - the use of disposables - multiproduct versus dedicated production - design principles for chromatography media and filters - ultrafiltration principles and optimization - risk assessments - characterization studies - design space - platform technologies - process analytical technologies (PATs) - biogenerics - comparability assessments Key Features: - new approaches to process optimiaztion - use of patform technologies - applying risk assessment to process design

Handbook of Process Chromatography Book

Handbook of Process Chromatography


  • Author : Gail K. Sofer
  • Publisher : Academic Press
  • Release Date : 1997-07-08
  • Genre: Science
  • Pages : 387
  • ISBN 10 : STANFORD:36105019357438

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Handbook of Process Chromatography Book Description :

With examples from companies with establised processes and approved biotherapeutics, this pack considers the entire scope of process chromatography, including scale-up, regulatory issues, equipment, evaluation studies, scheduling and cost effectiveness.

Handbook of Separation Process Technology Book
Score: 5
From 1 Ratings

Handbook of Separation Process Technology


  • Author : Ronald W. Rousseau
  • Publisher : John Wiley & Sons
  • Release Date : 1987-05-13
  • Genre: Technology & Engineering
  • Pages : 1024
  • ISBN 10 : 047189558X

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Handbook of Separation Process Technology Book Description :

Surveys the selection, design, and operation of most of the industrially important separation processes. Discusses the underlying principles on which the processes are based, and provides illustrative examples of the use of the processes in a modern context. Features thorough treatment of newer separation processes based on membranes, adsorption, chromatography, ion exchange, and chemical complexation. Includes a review of historically important separation processes such as distillation, absorption, extraction, leaching, and crystallization and considers these techniques in light of recent developments affecting them.

Handbook of Bioseparations Book
Score: 5
From 1 Ratings

Handbook of Bioseparations


  • Author : Satinder Ahuja
  • Publisher : Elsevier
  • Release Date : 2000-06-23
  • Genre: Science
  • Pages : 722
  • ISBN 10 : 0080507794

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Handbook of Bioseparations Book Description :

It is generally recognized that the commercial success of biotechnology products is highly dependent on the successful development and application of high-powered separation and purification methods. In this practical and authoritative handbook, the separation of proteins, nucleic acids, and oligonucleotides from biological matrices is covered from analytical to process scales. Also included in a chapter on the separation of monoclonal antibodies, which have found numerous uses as therapeutic and diagnostic agents. Analytical techniques include an interesting montage of chromatographic methods, capillary electrophoresis, isoelectric focusing, and mass spectrometry. Among separation and purification methods, liquid-liquid distribution, displacement chromatography, expanded bed adsorption, membrane chromatography, and simulated moving bed chromatography are covered at length. Regulatory and economic considerations are addressed, as are plant and process equipment and engineering process control. A chapter on future developments highlights the application of DNA chip arrays as well as evolving methodologies for a large number of drugs that are under development for treatment of cancer, AIDS, rheumatoid arthritis, and Alzheimer's disease. Handbook of Bioseparations serves as an essential reference and guidebook for separation scientists working in the pharmaceutical and biotechnology industries, academia, and government laboratories. Key Features * Covers bioseparations of proteins, nucleic acids, and monoclonal antibodies * Encompasses both analytical and process-scale methods * Elucidates the importance of engineering process control * Details selection of plant and process equipment * Addresses economic considerations * Discusses future developments

Handbook of Methods and Instrumentation in Separation Science Book

Handbook of Methods and Instrumentation in Separation Science


  • Author :
  • Publisher : Academic Press
  • Release Date : 2009-11-11
  • Genre: Science
  • Pages : 880
  • ISBN 10 : 0123757274

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Handbook of Methods and Instrumentation in Separation Science Book Description :

Handbook of Methods and Instrumentation in Separation Science, Volume 1 provides concise overviews and summaries of the main methods used for separation. It is based on the Encyclopedia of Separation Science. The handbook focuses on the principles of methods and instrumentation. It provides general concepts concerning the subject matter; it does not present specific procedures. This volume discusses the separation processes including affinity methods, analytical ultracentrifugation, centrifugation, chromatography, and use of decanter centrifuge and dye. Each methodology is defined and compared with other separation processes. It also provides specific techniques, principles, and theories concerning each process. Furthermore, the handbook presents the applications, benefits, and validation of the processes described in this book. This handbook is an excellent reference for biomedical researchers, environmental and production chemists, flavor and fragrance technologists, food and beverage technologists, academic and industrial librarians, and nuclear researchers. Students and novices will also find this handbook useful for practice and learning. One-stop source for information on separation methods General overviews for quick orientation Ease of use for finding results fast Expert coverage of major separation methods Coverage of techniques for all sizes of samples, pico-level to kilo-level

A Practical Handbook of Preparative HPLC Book

A Practical Handbook of Preparative HPLC


  • Author : Donald A Wellings
  • Publisher : Elsevier
  • Release Date : 2011-04-18
  • Genre: Technology & Engineering
  • Pages : 176
  • ISBN 10 : 0080458858

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A Practical Handbook of Preparative HPLC Book Description :

This book is a distillation of twenty years of practical experience of the high pressure liquid chromatography (HPLC) process. Deliberately steering clear of complex theoretical aspects, this book concentrates on the everyday problems associated with the technique, making it perfect for frequent use in the laboratory and for those in the pharmaceutical, agrochemical and biotechnology industries for the analysis and purification of drugs, small molecules, proteins and DNA. This book... •Provides practical, hands-on advice based on years of experience •Will help ensure optimal design, equipment and separation results for your particular task •Presents system layouts from laboratory to process scale •Will help you to devise or improve record-keeping and documentation systems ·Provides practical, hands-on advice based on years of experience ·Will help ensure optimal design, equipment and separation results for your particular task ·Presents system layouts from laboratory to process scale ·Will help you to devise or improve record-keeping and documentation systems

Handbook of Downstream Processing Book

Handbook of Downstream Processing


  • Author : E. Goldberg
  • Publisher : Taylor & Francis
  • Release Date : 1997
  • Genre: Science
  • Pages : 720
  • ISBN 10 : 0751403644

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Handbook of Downstream Processing Book Description :

The last two decades have witnessed a phenomenal growth in the field of genetic or biochemical engineering, and a variety of products has been developed and marketed through the manipulation and growth of different types of microorganisms and the recovery and purification of the associated products.

Process Chromatography Book

Process Chromatography


  • Author : Gail K. Sofer
  • Publisher : Academic Press
  • Release Date : 2015-09-02
  • Genre: Science
  • Pages : 96
  • ISBN 10 : 9781483289175

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Process Chromatography Book Description :

Research and development into biological products for therapeutic use has increased dramatically over the last 10 years. With this, strict regulatory requirements have been imposed by authorities such as the U.S. Food & Drug Administration, so that today validation has become a key issue in the biopharmaceutical industry. This concise book addresses validation issues in the chromatography of biotherapeutics. It covers process design, qualification and validation, including an overview of analytical techniques commonly used in the validation of processes. A concluding section comments on product changeover and presents four case studies.

Handbook of Biogeneric Therapeutic Proteins Book

Handbook of Biogeneric Therapeutic Proteins


  • Author : Sarfaraz K. Niazi
  • Publisher : CRC Press
  • Release Date : 2002-08-15
  • Genre: Medical
  • Pages : 584
  • ISBN 10 : 9781000611328

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Handbook of Biogeneric Therapeutic Proteins Book Description :

More than 20 billion dollars worth of biopharmaceuticals are scheduled to go off-patent by 2006. Given the strong political impetus and the development of technological tools that can answer the questions regulatory authorities may raise, it is inevitable that the FDA and EMEA will allow biogeneric or biosimilar products. Even with all the regulato

Handbook of Advanced Chromatography  Mass Spectrometry Techniques Book

Handbook of Advanced Chromatography Mass Spectrometry Techniques


  • Author : Michal Holcapek
  • Publisher : Elsevier
  • Release Date : 2017-09-07
  • Genre: Science
  • Pages : 520
  • ISBN 10 : 9780128117330

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Handbook of Advanced Chromatography Mass Spectrometry Techniques Book Description :

Handbook of Advanced Chromatography /Mass Spectrometry Techniques is a compendium of new and advanced analytical techniques that have been developed in recent years for analysis of all types of molecules in a variety of complex matrices, from foods to fuel to pharmaceuticals and more. Focusing on areas that are becoming widely used or growing rapidly, this is a comprehensive volume that describes both theoretical and practical aspects of advanced methods for analysis. Written by authors who have published the foundational works in the field, the chapters have an emphasis on lipids, but reach a broader audience by including advanced analytical techniques applied to a variety of fields. Handbook of Advanced Chromatography / Mass Spectrometry Techniques is the ideal reference for those just entering the analytical fields covered, but also for those experienced analysts who want a combination of an overview of the techniques plus specific and pragmatic details not often covered in journal reports. The authors provide, in one source, a synthesis of knowledge that is scattered across a multitude of literature articles. The combination of pragmatic hints and tips with theoretical concepts and demonstrated applications provides both breadth and depth to produce a valuable and enduring reference manual. It is well suited for advanced analytical instrumentation students as well as for analysts seeking additional knowledge or a deeper understanding of familiar techniques. Includes UHPLC, HILIC, nano-liquid chromatographic separations, two-dimensional LC-MS (LCxLC), multiple parallel MS, 2D-GC (GCxGC) methodologies for lipids analysis, and more Contains both practical and theoretical knowledge, providing core understanding for implementing modern chromatographic and mass spectrometric techniques Presents chapters on the most popular and fastest-growing new techniques being implemented in diverse areas of research

Ewing s Analytical Instrumentation Handbook  Fourth Edition Book

Ewing s Analytical Instrumentation Handbook Fourth Edition


  • Author : Nelu Grinberg
  • Publisher : CRC Press
  • Release Date : 2019-02-21
  • Genre: Medical
  • Pages : 975
  • ISBN 10 : 9781351644310

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Ewing s Analytical Instrumentation Handbook Fourth Edition Book Description :

This handbook is a guide for workers in analytical chemistry who need a starting place for information about a specific instrumental technique. It gives a basic introduction to the techniques and provides leading references on the theory and methodology for an instrumental technique. This edition thoroughly expands and updates the chapters to include concepts, applications, and key references from recent literature. It also contains a new chapter on process analytical technology.

Column Handbook for Size Exclusion Chromatography Book

Column Handbook for Size Exclusion Chromatography


  • Author : Chi-san Wu
  • Publisher : Elsevier
  • Release Date : 1999-03-19
  • Genre: Science
  • Pages : 637
  • ISBN 10 : 9780080529394

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Column Handbook for Size Exclusion Chromatography Book Description :

Column Handbook for Size Exclusion Chromatography is the first comprehensive reference to provide everything one needs to know about commercial analytical and preparative columns for size exclusion and gel filtration chromatography (SEC and GFC). SEC is now widely used as a quality assurance method in the polymer industry (both synthetic and biopolymers) to determine molecular weight and molecular weight distribution. The Handbook contains contributions from every column manufacturer around the world and from many experienced column users. It covers the technology, characterization, application, evaluation, maintenance, and quality control of analytical and preparative columns for SEC and GFC. Also included are columns for two closely related techniques, hydrodynamic chromatography and high osmotic pressure chromatography. Key Features * Evaluate and select columns with confidence for specific applications * Optimize separations and improve the ruggedness of analytical methods * Extend the service time of a column * Establish a quality-control program to ensure consistency in column performance * Avoid the expense of column damage or purchases that do not give the expected results

Handbook Of Size Exclusion Chromatography And Related Techniques Book

Handbook Of Size Exclusion Chromatography And Related Techniques


  • Author : Chi-San Wu
  • Publisher : CRC Press
  • Release Date : 2003-11-04
  • Genre: Science
  • Pages : 716
  • ISBN 10 : 9780824757793

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Handbook Of Size Exclusion Chromatography And Related Techniques Book Description :

Documenting critical advances in this rapidly evolving field, the Second Edition highlights the need for new applications and technologies that assist in the determination of molecular weight and molecular weight distributions of polymers in an accurate, efficient manner. This volume presents the latest findings from a international team of specialists and continues to inspire and extend practical applications of size exclusion chromatography (SEC). It includes six new chapters covering high-speed size exclusion chromatography, SEC of low molecular weight materials, and the extended family of techniques, from two-dimensional liquid chromatography to high osmotic pressure chromatography.

CRC Handbook of Chromatography Book

CRC Handbook of Chromatography


  • Author : Kumar D. Mukherjee
  • Publisher : CRC Press
  • Release Date : 1993-05-06
  • Genre: Science
  • Pages : 544
  • ISBN 10 : 0849330394

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CRC Handbook of Chromatography Book Description :

Handbook of Chromatography: Analysis of Lipids provides a valuable review of state-of-the-art applications of chromatographic techniques (TLC, GC, HPLC) and other analytical techniques. Much of this volume is devoted to applications of HPLC (including supercritical fluid chromatography) in the analysis of lipids such as fatty acids, oxygenated fatty acids, enantiomeric acyl- and alkylglycerols, and lipoproteins. The handbook also provides extensive coverage of applications of combinations of various chromatographic techniques used in the analysis of ozonides, anacardic acids, glycerophospholipids, products of lipolysis, artifacts and contaminants in edible fats, acylated proteins, non-caloric lipids, lipophilic vitamins, acyl-Coenzyme A thioesters, dolichols, mycolic acids, technical fats and fat products, and liposomes. Handbook of Chromatography: Analysis of Lipids will be a useful reference for oil chemists, biochemists, fat science technologists, and other scientists involved in lipid research.

The Handbook of Metabolic Phenotyping Book

The Handbook of Metabolic Phenotyping


  • Author : John C. Lindon
  • Publisher : Elsevier
  • Release Date : 2018-10-04
  • Genre: Science
  • Pages : 619
  • ISBN 10 : 9780128122945

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The Handbook of Metabolic Phenotyping Book Description :

The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics. Contains theoretical and practical explanations of all the main analytical chemistry techniques used in metabolic phenotyping Explores, in detail, the many diverse statistical approaches used in the field Offers practical tips for successfully conducting metabolic phenotyping studies Features reviews of all of the various fields of activity relating to human studies

Handbook of Solid Phase Microextraction Book

Handbook of Solid Phase Microextraction


  • Author : Janusz Pawliszyn
  • Publisher : Elsevier
  • Release Date : 2011-11-29
  • Genre: Science
  • Pages : 496
  • ISBN 10 : 9780123914491

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Handbook of Solid Phase Microextraction Book Description :

The relatively new technique of solid phase microextraction (SPME) is an important tool to prepare samples both in the lab and on-site. SPME is a "green" technology because it eliminates organic solvents from analytical laboratory and can be used in environmental, food and fragrance, and forensic and drug analysis. This handbook offers a thorough background of the theory and practical implementation of SPME. SPME protocols are presented outlining each stage of the method and providing useful tips and potential pitfalls. In addition, devices and fiber coatings, automated SPME systems, SPME method development, and In Vivo applications are discussed. This handbook is essential for its discussion of the latest SPME developments as well as its in depth information on the history, theory, and practical application of the method. Practical application of Solid Phase Microextraction methods including detailed steps Provides history of extraction methods to better understand the process Suitable for all levels, from beginning student to experienced practitioner

Liquid Chromatography Book

Liquid Chromatography


  • Author : Salvatore Fanali
  • Publisher : Elsevier
  • Release Date : 2017-06-22
  • Genre: Science
  • Pages : 808
  • ISBN 10 : 9780128093450

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Liquid Chromatography Book Description :

Liquid Chromatography: Fundamentals and Instrumentation, Second Edition, is a single source of authoritative information on all aspects of the practice of modern liquid chromatography. It gives those working in both academia and industry the opportunity to learn, refresh, and deepen their understanding of new fundamentals and instrumentation techniques in the field. In the years since the first edition was published, thousands of papers have been released on new achievements in liquid chromatography, including the development of new stationary phases, improvement of instrumentation, development of theory, and new applications in biomedicine, metabolomics, proteomics, foodomics, pharmaceuticals, and more. This second edition addresses these new developments with updated chapters from the most expert researchers in the field. Emphasizes the integration of chromatographic methods and sample preparation Explains how liquid chromatography is used in different industrial sectors Covers the most interesting and valuable applications in different fields, e.g., proteomic, metabolomics, foodomics, pollutants and contaminants, and drug analysis (forensic, toxicological, pharmaceutical, biomedical) Includes references and tables with commonly used data to facilitate research, practical work, comparison of results, and decision-making

Expanded Bed Chromatography Book

Expanded Bed Chromatography


  • Author : B. Mattiasson
  • Publisher : Springer Science & Business Media
  • Release Date : 1999-12-31
  • Genre: Science
  • Pages : 271
  • ISBN 10 : 0792361237

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Expanded Bed Chromatography Book Description :

Expanded bed adsorption chromatography is a novel processing technique for the purification of biomolecules, combining clarification, concentration and initial purification in one step. By such an integration it is possible to reduce the number of steps in the purification process, to shorten the processing time and to improve the yields. The technology is new, and interesting developments have taken place concerning the adsorbents, the processing technology and potential applications. Both small-scale laboratory processes and larger industrial processes are being developed. Expanded bed chromatography is one of the most exciting new developments in downstream processing in recent years. The technology will be a standard procedure when new biotechnological processes are being developed.

Handbook of Thin Layer Chromatography Book
Score: 5
From 1 Ratings

Handbook of Thin Layer Chromatography


  • Author : Joseph Sherma
  • Publisher : CRC Press
  • Release Date : 2003-04-18
  • Genre: Science
  • Pages : 1048
  • ISBN 10 : 9780824748661

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Handbook of Thin Layer Chromatography Book Description :

In this third edition, more than 40 renowned authorities introduce and update chapters on the theory, fundamentals, techniques, and instrumentation of thin-layer chromatography (TLC) and high-performance thin-layer chromatography (HPTLC), highlighting the latest procedures and applications of TLC to 19 important compound classes and coverage of TLC applications by compound type. Easily adaptable to industrial scenarios , the Handbook of Thin-Layer Chromatography, Third Edition supports practical research strategies with extensive tables of data, offers numerous figures that illustrate techniques and chromatograms, and includes a glossary as well as a directory of equipment suppliers.

Handbook of Synthetic Organic Chemistry Book

Handbook of Synthetic Organic Chemistry


  • Author : Michael C. Pirrung
  • Publisher : Academic Press
  • Release Date : 2016-08-30
  • Genre: Science
  • Pages : 288
  • ISBN 10 : 9780128095041

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Handbook of Synthetic Organic Chemistry Book Description :

Handbook of Synthetic Organic Chemistry, Second Edition updates and expands the author’s popular 2007 work, Synthetic Organic Chemist’s Companion. This new handbook provides valuable, practical guidance; incorporates corrections, and includes coverage on important topics, such as lyophylization, crystallization, precipitation, HPLC detectors, gases, and microwave reactions. The book maintains the useful organization of the author’s earlier work, beginning with a basic overview and walking through every practical step of the process of organic synthesis, from reagents, solvents, and temperature control, to documentation, implementation, purification, and analytical methods for the product. From planning and setting up reactions, to recording them, the book provides insight and valuable guidance into every step of the process. Practical guidance for planning, working up, documenting, analyzing, and improving reactions in synthetic organic chemistry