History of Immunotoxicology Book

History of Immunotoxicology


  • Author : Jacques Descotes
  • Publisher : Academic Press
  • Release Date : 2019-04-15
  • Genre: Medical
  • Pages : 125
  • ISBN 10 : 0128096799

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History of Immunotoxicology Excerpt :

History of Immunotoxicology offers the first book-length exploration of the development and importance of the field of immunotoxicology, describing the adverse health effects involving the immune system, hypersensitivity and autoimmunity. It explores new avenues of research and immunotoxicity evaluation, regulatory aspects of immunotoxicology, and the withdrawal/banning from the market of several approved drugs and chemicals due to their immunotoxic effects. In addition, clinical manifestations of immunotoxicity, such as anaphylaxis, opportunistic infections, lymphomas, cytokine storm, and immunotherapy are addressed. Finally, the book considers how the recent past can provide insights on the future practice of immunotoxicology. As preventive measures are implemented to reduce risks, including banning of chemicals or applications of one given chemical, current toxicologists may not be aware of the toxicity potential of chemicals. This book will be of interest to students and researchers in government, industry and academia who have an interest in immunotoxicology. Examines the development of immunotoxicology Provides context to current debates on the actual toxicity potential of chemicals Covers major developments and areas of immunotoxicology

Introduction To Immunotoxicology Book

Introduction To Immunotoxicology


  • Author : Jacques Descotes
  • Publisher : CRC Press
  • Release Date : 2003-09-02
  • Genre: Medical
  • Pages : 196
  • ISBN 10 : 9780203362549

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Introduction To Immunotoxicology Excerpt :

This text provides a concise and comprehensive introduction to key immunotoxicological issues for all those interested in, but with no prior knowledge of, this area of toxicology. The first section explores the health consequences of immunotoxicity, namely the adverse effects related to chemically-induced immunosuppression and immunostimulation, hypersensitivity reactions and autoimmune diseases, with an overview of major immunotoxicants. The second part describes the latest methods used to detect and evaluate, preclinically and clinically, the unexpected immunotoxic effects of xenobiotics. Trends in implementing strategies and recent changes to the regulatory aspects are also considered. The third section examines possible future developments, including In Vitro methods, biomarkers of immunotixicity and risk assessment.

Principles and Methods of Immunotoxicology Book

Principles and Methods of Immunotoxicology


  • Author : Jacques Descotes
  • Publisher : Elsevier
  • Release Date : 2004-10-14
  • Genre: Medical
  • Pages : 400
  • ISBN 10 : 9780080472997

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Principles and Methods of Immunotoxicology Excerpt :

This is a review of clinical adverse effects on the human immune system that may occur following drug treatments and chemcical exposures. Current and prospective models and assays that can be used to predict these adverse effects in animal toxicity studies or in human beings are described.

Immunotoxicology and Immunopharmacology Book

Immunotoxicology and Immunopharmacology


  • Author : Robert V. House
  • Publisher : CRC Press
  • Release Date : 2006-12-26
  • Genre: Medical
  • Pages : 678
  • ISBN 10 : 1420005448

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Immunotoxicology and Immunopharmacology Excerpt :

Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history,

Immunotoxicity Testing Book

Immunotoxicity Testing


  • Author : Jamie C. DeWitt
  • Publisher : Humana
  • Release Date : 2019-06-22
  • Genre: Medical
  • Pages : 412
  • ISBN 10 : 1493993224

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Immunotoxicity Testing Excerpt :

This fully updated volume utilizes the expertise of scientists currently engaged in immunotoxicity testing to provide the reader with lab-ready procedures and the background information needed to identify effective testing approaches. Dedicated to identifying and describing exogenous agents that can modify immune function, uncovering modes and mechanisms of action for such agents, and translating data from the laboratory and from the clinic to better predict health risks as well as benefits to those who are exposed to immunomodulatory agents, immunotoxicity testing continues to be a vital field of study, and this collection highlights both the “tried and true” methods as well as alternative protocols that have been more recently developed. Written in the highly successful Methods in Molecular Biology format, chapters include introductions to their respective topics, lists of the necessary materials and reagents, step-by-step, readily reproducible laboratory protocols, and tips on troubleshooting and avoiding known pitfalls. Authoritative and practical, Immunotoxicity Testing: Methods and Protocols, Second Edition serves as a valuable contribution to the continued evolution and the application of immunotoxicity testing.

Immunotoxicology Of Environmental And Occupational Metals Book

Immunotoxicology Of Environmental And Occupational Metals


  • Author : Judith T Zelicoff
  • Publisher : CRC Press
  • Release Date : 1998-02-20
  • Genre: Science
  • Pages : 385
  • ISBN 10 : 9780748403905

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Immunotoxicology Of Environmental And Occupational Metals Excerpt :

Provides an overview of the effects of environmentally and occupationally important metals on the immune system and host defence. The fist ten chapters in the text focus on particular metals or groups of metals, including arsenic, beryllium, cadmium, chromium, lead, mercury, nickel and vanadium. Subsequent chapters examine the immunotoxicological effects of trace metals such as indium and platinum and essential metals such as iron, zinc and copper. The main emphasis is on the in vivo and in vitro effects of these metals on host immune responses in a variety of mammalian species including humans. Each chapter also briefly reviews the history, use, occurrence, biology and toxicology of the metals.

Information Resources in Toxicology Book

Information Resources in Toxicology


  • Author : P.J. Bert Hakkinen
  • Publisher : Academic Press
  • Release Date : 2009-08-19
  • Genre: Science
  • Pages : 1552
  • ISBN 10 : 0080920039

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Information Resources in Toxicology Excerpt :

This latest version of Information Resources in Toxicology (IRT) continues a tradition established in 1982 with the publication of the first edition in presenting an extensive itemization, review, and commentary on the information infrastructure of the field. This book is a unique wide-ranging, international, annotated bibliography and compendium of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. Thoroughly updated, the current edition analyzes technological changes and is rife with online tools and links to Web sites. IRT-IV is highly structured, providing easy access to its information. Among the “hot topics covered are Disaster Preparedness and Management, Nanotechnology, Omics, the Precautionary Principle, Risk Assessment, and Biological, Chemical and Radioactive Terrorism and Warfare are among the designated. • International in scope, with contributions from over 30 countries • Numerous key references and relevant Web links • Concise narratives about toxicologic sub-disciplines • Valuable appendices such as the IUPAC Glossary of Terms in Toxicology • Authored by experts in their respective sub-disciplines within toxicology

Principles and Practice of Toxicology in Public Health Book

Principles and Practice of Toxicology in Public Health


  • Author : Ira Richards
  • Publisher : Jones & Bartlett Learning
  • Release Date : 2008
  • Genre: Health & Fitness
  • Pages : 464
  • ISBN 10 : 9780763738235

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Principles and Practice of Toxicology in Public Health Excerpt :

In Five Sections, this reference Offers An Introduction To The Field, As WellAs The Basics Of Toxicology Principles, Chemical Toxicity, Ecotoxicology, AndToxicology Practice.

Information Resources in Toxicology Book

Information Resources in Toxicology


  • Author : Steve Gilbert
  • Publisher : Academic Press
  • Release Date : 2020-05-16
  • Genre: Medical
  • Pages : 1054
  • ISBN 10 : 9780128137253

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Information Resources in Toxicology Excerpt :

This new fifth edition of Information Resources in Toxicology offers a consolidated entry portal for the study, research, and practice of toxicology. Both volumes represents a unique, wide-ranging, curated, international, annotated bibliography, and directory of major resources in toxicology and allied fields such as environmental and occupational health, chemical safety, and risk assessment. The editors and authors are among the leaders of the profession sharing their cumulative wisdom in toxicology’s subdisciplines. This edition keeps pace with the digital world in directing and linking readers to relevant websites and other online tools. Due to the increasing size of the hardcopy publication, the current edition has been divided into two volumes to make it easier to handle and consult. Volume 1: Background, Resources, and Tools, arranged in 5 parts, begins with chapters on the science of toxicology, its history, and informatics framework in Part 1. Part 2 continues with chapters organized by more specific subject such as cancer, clinical toxicology, genetic toxicology, etc. The categorization of chapters by resource format, for example, journals and newsletters, technical reports, organizations constitutes Part 3. Part 4 further considers toxicology’s presence via the Internet, databases, and software tools. Among the miscellaneous topics in the concluding Part 5 are laws and regulations, professional education, grants and funding, and patents. Volume 2: The Global Arena offers contributed chapters focusing on the toxicology contributions of over 40 countries, followed by a glossary of toxicological terms and an appendix of popular quotations related to the field. The book, offered in both print and electronic formats, is carefully structured, indexed, and cross-referenced to enable users to easily find answers to their questions or serendipitously locate useful knowledge they were not originally aware they needed. Among the many timely topics receiving incre

Avian Immunology Book

Avian Immunology


  • Author : Karel A. Schat
  • Publisher : Academic Press
  • Release Date : 2012-12-02
  • Genre: Medical
  • Pages : 456
  • ISBN 10 : 9780123972729

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Avian Immunology Excerpt :

The second edition of Avian Immunology provides an up-to-date overview of the current knowledge of avian immunology. From the ontogeny of the avian immune system to practical application in vaccinology, the book encompasses all aspects of innate and adaptive immunity in chickens. In addition, chapters are devoted to the immunology of other commercially important species such as turkeys and ducks, and to ecoimmunology summarizing the knowledge of immune responses in free-living birds often in relation to reproductive success. The book contains a detailed description of the avian innate immune system, encompassing the mucosal, enteric, respiratory and reproductive systems. The diseases and disorders it covers include immunodepressive diseases and immune evasion, autoimmune diseases, and tumors of the immune system. Practical aspects of vaccination are examined as well. Extensive appendices summarize resources for scientists including cell lines, inbred chicken lines, cytokines, chemokines, and monoclonal antibodies. The world-wide importance of poultry protein for the human diet, as well as the threat of avian influenza pandemics like H5N1 and heavy reliance on vaccination to protect commercial flocks makes this book a vital resource. This book provides crucial information not only for poultry health professionals and avian biologists, but also for comparative and veterinary immunologists, graduate students and veterinary students with an interest in avian immunology. With contributions from 33 of the foremost international experts in the field, this book provides the most up-to-date review of avian immunology so far Contains a detailed description of the avian innate immune system reviewing constitutive barriers, chemical and cellular responses; it includes a comprehensive review of avian Toll-like receptors Contains a wide-ranging review of the "ecoimmunology" of free-living avian species, as applied to studies of population dynamics, and reviews methods and resourc

Clinical Immunotoxicology Book

Clinical Immunotoxicology


  • Author : David S Newcombe
  • Publisher : CRC Press
  • Release Date : 1992-06-30
  • Genre: Medical
  • Pages : 470
  • ISBN 10 : 1439805415

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Clinical Immunotoxicology Excerpt :

This text is a comprehensive source of information on the toxic effects of environmental, industrial, and pharmacological agents on the human immune system. Focusing entirely on human immunotoxicology, without relying on animal models, the book explains the basic principles of immunotoxicology defines the mechanisms by which immunotoxins act, describes the clinical expression of immunotoxic disorders in the lung, skin, and other target organs, offers practical guidelines for early detection and control of host defense dysfunctions, and explores strategies for assessing the short- and long-term health effects of new and old chemicals and biologicals. The book includes extensive discussions on the role of low-dose, chronic immunosuppression in cancer, as well as on specific environmental and occupational immunotoxins and immunotoxic drugs used in hematology, anesthesiology, oncology and transplantation surgery.

Immunotoxicology and Immunopharmacology  Third Edition Book

Immunotoxicology and Immunopharmacology Third Edition


  • Author : Robert V. House
  • Publisher : CRC Press
  • Release Date : 2006-12-26
  • Genre: Medical
  • Pages : 672
  • ISBN 10 : 9781420005448

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Immunotoxicology and Immunopharmacology Third Edition Excerpt :

Continuing the tradition set by the first and second editions, each a bestseller in its own right, the third edition of Immunotoxicology and Immunopharmacology provides reviews of environmental agents, updated to reflect the latest information on how these agents influence immune system function and health. For the first time in the book's history, an entire section covers the phylogeny and ontogeny of the immune system, spanning levels of biological complexity from earthworms to marine mammals.

Schalm s Veterinary Hematology Book

Schalm s Veterinary Hematology


  • Author : Marjory B. Brooks
  • Publisher : John Wiley & Sons
  • Release Date : 2022-04-12
  • Genre: Medical
  • Pages : 1428
  • ISBN 10 : 9781119500506

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Schalm s Veterinary Hematology Excerpt :

SCHALM’S VETERINARY HEMATOLOGY An updated guide to veterinary hematology with expanded coverage on a variety of topics The revised seventh edition of Schalm’s Veterinary Hematology is updated to provide a comprehensive review of all topics related to disorders of the blood in animals. Designed as a gold-standard reference, this text covers a wide range of species in both confined and free-range populations, reflects the most recent trends in hematology diagnostics, and discusses recent advances in traditional techniques. Edited and written by an international team of experts in the field, the book represents an accessible yet in-depth resource for information on veterinary hematology. The new edition includes a hemolymphatic tissue section that covers current understanding of basic science and the species-specific hematology section is further expanded from previous editions. New chapters address emerging topics in hematology, and existing chapters have been revised and rearranged to improve readability and simplify access to the material. This seventh edition: Updates the most complete reference on veterinary hematology across species Contains a new section on basic biology of hemolymphatic tissues Expands coverage of species-specific hematology Presents new and emerging topics in blood disorders and diagnostic techniques Features a reorganized contents list for an integrated, easy to use reference Written for veterinary clinical pathologists and residents, diagnostic laboratory staff, internists, and specialists, Schalm’s Veterinary Hematology is the most comprehensive and up-to-date reference on the topic.

Immunotoxicity  Immune Dysfunction  and Chronic Disease Book

Immunotoxicity Immune Dysfunction and Chronic Disease


  • Author : Rodney R. Dietert
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-06-05
  • Genre: Medical
  • Pages : 452
  • ISBN 10 : 9781617798122

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Immunotoxicity Immune Dysfunction and Chronic Disease Excerpt :

Chronic diseases are the leading cause of deaths worldwide and according to the World Economics Council and the Harvard School of Public Health, the cost of chronic diseases is expected to reach a staggering 48% of global gross domestic product by the year 2030. The urgency of the issue was demonstrated in 2011 when for only the second time in its existence, the U.N. General Assembly brought a health issue to the floor for consideration: chronic diseases. To date, most considerations of the issue have approached the topic from the vantage point that chronic diseases are a myriad of largely unconnected diseases and conditions arising in diverse tissues, organs and physiological systems. This book, Immunotoxicity, Immune Dysfuction, and Chronic Disease, deviates from that prior model. It considers the interconnectivity of chronic diseases with both environmental insult of the immune system and subsequent immune dysfunction and inflammatory dysregulation as the underlying basis for many, if not most, chronic diseases. This change in the perception of environment-immune linkages to chronic disease is significant and has immediate implications both for the prevention of disease as well as for the development of more effective therapeutic approaches. Rather than considering environmental factors and types of reported immune alterations (e.g., depressed humoral immunity) as is common in books involving immunotoxicity, the present book approaches the environment-immune-disease triad from the standpoint of the disease. Each chapter emphasizes one or more specific immune dysfunction-based chronic disease(s) or condition(s) (e.g., asthma, atherosclerosis, multiple sclerosis, lupus) and describes: 1) the suggested environmental risk factors, 2) the underlying immune dysfunction(s) associated with the disease and 3) the overall health consequences of the disease. This book is an early entry for a new Toxicology book series for Springer titled: Molecular and Integrative Toxicolog