How To Optimize Fluid Bed Processing Technology

How to Optimize Fluid Bed Processing Technology

• Author : Dilip Parikh
• Publisher : Academic Press
• Release Date : 2017-04-04
• Genre: Medical
• Pages : 210
• ISBN 10 : 9780128047286

How to Optimize Fluid Bed Processing Technology: Part of the Expertise in Pharmaceutical Process Technology Series addresses the important components of fluid bed granulation, providing answers to problems that commonly arise and using numerous practical examples and case studies as reference. This book covers the theoretical concepts involved in fluidization, also providing a description of the choice and functionality of equipment. Additional chapters feature key aspects of the technology, including formulation requirements, process variables, process scale-up, troubleshooting, new development, safety, and process evaluation. Given its discussion of theoretical principles and practical solutions, this is a go-to resource for all those scientists and new researchers working with fluid bed granulation as a unit operation. Written by an expert in the field with several years of experience in product development, manufacturing, plant operations, and process engineering Illustrates when fluid bed granulation is needed, when to use less common fluid bed granulation methods, and the advantages of fluid bed granulation when compared to other granulation techniques Offers troubleshooting tips and practical advice for scientists working with this technique

Fluid Bed Technology in Materials Processing

• Author : C. K. Gupta
• Publisher : CRC Press
• Release Date : 1998-12-28
• Genre: Technology & Engineering
• Pages : 526
• ISBN 10 : 1420049860

Fluid Bed Technology in Materials Processing comprehensively covers the various aspects of fluidization engineering and presents an elaborate examination of the applications in a multitude of materials processing techniques. This singular resource discusses: All the basic aspects of fluidization essential to understand and learn about various techniques The range of industrial applications Several examples in extraction and process metallurgy Fluidization in nuclear engineering and nuclear fuel cycle with numerous examples Innovative techniques and several advanced concepts of fluidization engineering, including use and applications in materials processing as well as environmental and bio-engineering Pros and cons of various fluidization equipment and specialty of their applications, including several examples Design aspects and modeling Topics related to distributors effects and flow regimes A separate chapter outlines the importance of fluidization engineering in high temperature processing, including an analysis of the fundamental concepts and applications of high temperature fluidized bed furnaces for several advanced materials processing techniques. Presenting information usually not available in a single source, Fluid Bed Technology in Materials Processing serves Fluidization engineers Practicing engineers in process metallurgy, mineral engineering, and chemical metallurgy Researchers in the field of chemical, metallurgical, nuclear, biological, environmental engineering Energy engineering professionals High temperature scientists and engineers Students and professionals who adopt modeling of fluidization in their venture for design and scale up

Handbook of Pharmaceutical Granulation Technology

• Author : Dilip M. Parikh
• Publisher : CRC Press
• Release Date : 2021-05-12
• Genre: Medical
• Pages : 904
• ISBN 10 : 9781000366389

This fully revised edition of Handbook of Pharmaceutical Granulation Technology covers the rapid advances in the science of agglomeration, process control, process modelling, scale-up, emerging particle engineering technologies, along with current regulatory changes presented by some of the prominent scientist and subject matter experts around the globe. Learn from more than 50 global subject matter experts who share their years of experience in areas ranging from drug delivery and pharmaceutical technology to advances in nanotechnology. Every pharmaceutical scientist should own a copy of this fourth edition resource. Key Features: Theoretical discussions covering granulation and engineering perspectives. Covers new advances in expert systems, process modelling and bioavailability Chapters on emerging technologies in particle engineering Updated Current research and developments in granulation technologies

Principles of Parenteral Solution Validation

• Author : Igor Gorsky
• Publisher : Academic Press
• Release Date : 2019-11-27
• Genre: Medical
• Pages : 298
• ISBN 10 : 9780128094464

Principles of Parenteral Solution Validation: A Practical Lifecycle Approach covers all aspects involved in the development and process validation of a parenteral product. By using a lifecycle approach, this book discusses the latest technology, compliance developments, and regulatory considerations and trends, from process design, to divesting. As part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin, this book incorporates numerous case studies and real-world examples that address timely problems and offer solutions to the daily challenges facing practitioners in this area. Discusses international and domestic regulatory considerations in every section Features callout boxes that contain points-of-interest for each segment of the audience so readers can quickly find their interests and needs Contains important topics, including risk management, the preparation and execution of properly designed studies, scale-up and technology transfer activities, problem-solving, and more

Bioceramics Biomimetic and Other Compatible Materials Features for Medical Applications

• Author : Stevo Najman
• Publisher : Springer Nature
• Release Date : 2023-01-01
• Genre: Technology & Engineering
• Pages : 408
• ISBN 10 : 9783031172694

This book reports on advanced biomaterials such as bioceramics, hydrogels, biopolymers, nanomaterials, membranes, and other compatible materials for medical applications. It introduces materials as bioactive coatings that utilize or mimic natural mechanisms and structures important for tissue and organ healing and repair. One section of the book is devoted to bone substitutes and osteogenic biomaterials. It also describes biomaterial-cell-tissue interactions, which are of critical importance for various applications in regenerative medicine, orthopedics, and implant functions. The chapters present fabrication methods and testing of various materials for medical applications. Special emphasis is given to natural patterns, theoretical models, and new insights into material characterization, particularly on fractal natural boundaries and mimicry designs taken from nature and implemented in photonics science and engineering. This multidisciplinary book is written by leading researchers and experts in their fields, and serves researchers, students, physicians, and engineers.

How to Integrate Quality by Efficient Design QbED in Product Development

• Author : Bhavishya Mittal
• Publisher : Academic Press
• Release Date : 2019-08-24
• Genre: Business & Economics
• Pages : 274
• ISBN 10 : 9780128173046

The development of a robust drug product requires juggling many competing priorities such as overcoming scientific challenges, following regulatory requirements, and managing business-related concerns. Unfortunately, despite large resources spent on R&D, multifactor productivity of pharmaceuticals is on the decline for several years now. Because of this business reality, pharmaceutical companies have seen a notable change in the traditional operating model and footprint over the past couple of decades. Outsourcing, in particular, has emerged as a successful business model for many pharmaceutical companies looking for ways to strategically increase their R&D capabilities and to augment their in-house resources. How to Integrate Quality by Efficient Design (QbED) in Product Development bridges the gap between theory and practice when it comes to strategic decision-making in a pharmaceutical research scenario. This book will introduce the concept of QbED and focus on various aspects such as patient-centric product designs, platform-based manufacturing technologies, business acuity, and regulatory strategies to balance the challenges in outsourcing with the need for strategic and statistically sound experiments rooted in good science. Detailed discussions will cover pharmaceutical business models, regulatory approval process, quality by design (QbD), business analytics, and manufacturing excellence specifically for small molecules and solid oral dosage forms. With the addition of case studies, flowcharts, diagrams, and data visualizations, How to Integrate Quality by Efficient Design (QbED) in Product Development will be a practical reference to help professionals working in the area of pharmaceutical drug development, strategy, and outsourcing management. Part of the Expertise in Pharmaceutical Process Technology series edited by Michael Levin Integrates pharmaceutical business models, economics, and outsourcing-related challenges into pharmaceutical product developmen

Fluid Bed Technology in Materials Processing

• Author : C. K. Gupta
• Publisher : CRC Press
• Release Date : 2019-09-27
• Genre: Uncategoriezed
• Pages : 528
• ISBN 10 : 036740009X

Fluid Bed Technology in Materials Processing comprehensively covers the various aspects of fluidization engineering and presents an elaborate examination of the applications in a multitude of materials processing techniques. This singular resource discusses: All the basic aspects of fluidization essential to understand and learn about various techniques The range of industrial applications Several examples in extraction and process metallurgy Fluidization in nuclear engineering and nuclear fuel cycle with numerous examples Innovative techniques and several advanced concepts of fluidization engineering, including use and applications in materials processing as well as environmental and bio-engineering Pros and cons of various fluidization equipment and specialty of their applications, including several examples Design aspects and modeling Topics related to distributors effects and flow regimes A separate chapter outlines the importance of fluidization engineering in high temperature processing, including an analysis of the fundamental concepts and applications of high temperature fluidized bed furnaces for several advanced materials processing techniques. Presenting information usually not available in a single source, Fluid Bed Technology in Materials Processing serves Fluidization engineers Practicing engineers in process metallurgy, mineral engineering, and chemical metallurgy Researchers in the field of chemical, metallurgical, nuclear, biological, environmental engineering Energy engineering professionals High temperature scientists and engineers Students and professionals who adopt modeling of fluidization in their venture for design and scale up

Computer aided applications in pharmaceutical technology

• Author : Ivana Masic
• Publisher : Elsevier Inc. Chapters
• Release Date : 2013-04-10
• Genre: Technology & Engineering
• Pages : 300
• ISBN 10 : 9780128091937

This chapter introduces the concept of computational fluid dynamics (CFD) and its applications in pharmaceutical technology. Basic theoretical explanations on the mathematics of fluid flow and numerical grids are provided. CFD is a versatile tool that is mainly used in complex dynamical process characterization. Examples of CFD applications in development of inhalers, analysis of dissolution apparatus hydrodynamics, and fluidized bed process simulations are presented.

Developing Solid Oral Dosage Forms

• Author : Yihong Qiu
• Publisher : Academic Press
• Release Date : 2016-11-08
• Genre: Medical
• Pages : 1176
• ISBN 10 : 9780128026373

Developing Solid Oral Dosage Forms: Pharmaceutical Theory and Practice, Second Edition illustrates how to develop high-quality, safe, and effective pharmaceutical products by discussing the latest techniques, tools, and scientific advances in preformulation investigation, formulation, process design, characterization, scale-up, and production operations. This book covers the essential principles of physical pharmacy, biopharmaceutics, and industrial pharmacy, and their application to the research and development process of oral dosage forms. Chapters have been added, combined, deleted, and completely revised as necessary to produce a comprehensive, well-organized, valuable reference for industry professionals and academics engaged in all aspects of the development process. New and important topics include spray drying, amorphous solid dispersion using hot-melt extrusion, modeling and simulation, bioequivalence of complex modified-released dosage forms, biowaivers, and much more. Written and edited by an international team of leading experts with experience and knowledge across industry, academia, and regulatory settings Includes new chapters covering the pharmaceutical applications of surface phenomenon, predictive biopharmaceutics and pharmacokinetics, the development of formulations for drug discovery support, and much more Presents new case studies throughout, and a section completely devoted to regulatory aspects, including global product regulation and international perspectives

Department of the Interior and Related Agencies Appropriations for 1983

• Author : United States. Congress. House. Committee on Appropriations. Subcommittee on Department of the Interior and Related Agencies
• Publisher : Unknown
• Release Date : 1982
• Genre: United States
• Pages : 1562
• ISBN 10 : STANFORD:36105119519879

Congressional Budget Request

• Author : United States. Department of Energy
• Publisher : Unknown
• Release Date : 1982
• Genre: Energy conservation
• Pages : null
• ISBN 10 : STANFORD:36105211276170

Generic Drug Product Development

• Author : Leon Shargel
• Publisher : CRC Press
• Release Date : 2013-10-24
• Genre: Medical
• Pages : 400
• ISBN 10 : 9781420086355

In this era of increased pharmaceutical industry competition, success for generic drug companies is dependent on their ability to manufacture therapeutic-equivalent drug products in an economical and timely manner, while also being cognizant of patent infringement and other legal and regulatory concerns. Generic Drug Product Development: Solid Oral Dosage Forms, Second Edition presents in-depth discussions from more than 30 noted specialists describing the development of generic drug products—from the raw materials to the development of a therapeutic-equivalent drug product to regulatory approval. Major topics discussed include: Active pharmaceutical ingredients Experimental formulation development, including a new section on Quality by Design (QbD) Scale-up Commercial product formulation Quality control and bioequivalence Drug product performance ANDA regulatory process Post-approval changes Post-marketing surveillance Legislative and patent challenges This second edition also contains a new chapter on the relationship between the FDA and the United States Pharmacopeia and in Chapter 4, using specific examples, the application of Quality by Design (QbD) during formulation development is examined.The book is a thorough guide to the development of solid oral generic dosage formulations. This textbook is ideal for the pharmaceutical industry, graduate programs in pharmaceutical sciences, and health professionals working in the area of generic drug development.

Food Waste Recovery

• Author : Charis M. Galanakis
• Publisher : Academic Press
• Release Date : 2020-12-01
• Genre: Technology & Engineering
• Pages : 560
• ISBN 10 : 9780128225929

Food Waste Recovery: Processing Technologies, Industrial Techniques, and Applications, Second Edition provides information on safe and economical strategies for the recapture of value compounds from food wastes while also exploring their re-utilization in fortifying foods and as ingredients in commercial products. Sections discuss the exploration of management options, different sources, the Universal Recovery Strategy, conventional and emerging technologies, and commercialization issues that target applications of recovered compounds in the food and cosmetics industries. This book is a valuable resource for food scientists, technologists, engineers, chemists, product developers, researchers, academics and professionals working in the food industry. Covers food waste management within the food industry by developing recovery strategies Provides coverage of processing technologies and industrial techniques for the recovery of valuable compounds from food processing by-products Explores the different applications of compounds recovered from food processing using three approaches: targeting by-products, targeting ingredients, and targeting bioactive applications

Energy a Continuing Bibliography with Indexes

• Author : Anonim
• Publisher : Unknown
• Release Date : 1981
• Genre: Fuel
• Pages : 492
• ISBN 10 : UOM:39015013034767

Water Insoluble Drug Formulation

• Author : Ron Liu
• Publisher : CRC Press
• Release Date : 2018-03-12
• Genre: Medical
• Pages : 781
• ISBN 10 : 9781351646826

Properties and Formulation: From Theory to Real-World Application Scientists have attributed more than 40 percent of the failures in new drug development to poor biopharmaceutical properties, particularly water insolubility. Issues surrounding water insolubility can postpone or completely derail important new drug development. Even the much-needed reformulation of currently marketed products can be significantly affected by these challenges. More recently it was reported that the percentage increased to 90% for the candidates of new chemical entities in the discovery stage and 75% for compounds under development. In the most comprehensive resource on the topic, this third edition of Water-Insoluble Drug Formulation brings together a distinguished team of experts to provide the scientific background and step-by-step guidance needed to deal with solubility issues in drug development. Twenty-three chapters systematically describe the detailed discussion on solubility theories, solubility prediction models, the aspects of preformulation, biopharmaceutics, pharmacokinetics, regulatory, and discovery support of water-insoluble drugs to various techniques used in developing delivery systems for water-insoluble drugs. This book includes more than 15 water-insoluble drug delivery systems or technologies, illustrated with case studies and featuring oral and parenteral applications. Highlighting the most current information and data available, this seminal volume reflects the significant progress that has been made in nearly all aspects of this field. The aim of this book is to provide a handy reference for pharmaceutical scientists in the handling of formulation issues related to water-insoluble drugs. In addition, this book may be useful to pharmacy and chemistry undergraduate students and pharmaceutical and biopharmaceutical graduate students to enhance their knowledge in the techniques of drug solubilization and dissolution enhancement.