Human Embryos and Preimplantation Genetic Technologies Book

Human Embryos and Preimplantation Genetic Technologies


  • Author : E. Scott Sills
  • Publisher : Academic Press
  • Release Date : 2019-05-01
  • Genre: Science
  • Pages : 222
  • ISBN 10 : 9780128167441

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Human Embryos and Preimplantation Genetic Technologies Excerpt :

Human Embryos and Preimplantation Genetic Technologies: Ethical, Social, and Public Policy Aspects presents the first holistic analysis of PGD and PGS as it is practiced and regulated worldwide. In addition to scientific and technical aspects, the book provides perspectives on the ethical, legal, religious, policy and social implications of global assisted reproduction technologies, including in Africa, Asia, Europe, North and South America, and Australia. Chapters cover history, ethics, feminism, family dynamics, psychological and interpersonal factors, the current state of PGD and PGS in 20 different sovereign nations and religious communities, and provide an analysis of public policy concerns and future directions. Provides an in-depth discussion of PGD and PGS as practiced and regulated worldwide Offers an accessible resource for researchers, medical professionals, patients, regulators and policymakers seeking expert opinions on PGS and PGD Contains chapters contributed by international clinicians, researchers and thought leaders in the field of assisted reproductive technology

Heritable Human Genome Editing Book

Heritable Human Genome Editing


  • Author : The Royal Society
  • Publisher : National Academies Press
  • Release Date : 2021-01-16
  • Genre: Medical
  • Pages : 238
  • ISBN 10 : 9780309671132

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Heritable Human Genome Editing Excerpt :

Heritable human genome editing - making changes to the genetic material of eggs, sperm, or any cells that lead to their development, including the cells of early embryos, and establishing a pregnancy - raises not only scientific and medical considerations but also a host of ethical, moral, and societal issues. Human embryos whose genomes have been edited should not be used to create a pregnancy until it is established that precise genomic changes can be made reliably and without introducing undesired changes - criteria that have not yet been met, says Heritable Human Genome Editing. From an international commission of the U.S. National Academy of Medicine, U.S. National Academy of Sciences, and the U.K.'s Royal Society, the report considers potential benefits, harms, and uncertainties associated with genome editing technologies and defines a translational pathway from rigorous preclinical research to initial clinical uses, should a country decide to permit such uses. The report specifies stringent preclinical and clinical requirements for establishing safety and efficacy, and for undertaking long-term monitoring of outcomes. Extensive national and international dialogue is needed before any country decides whether to permit clinical use of this technology, according to the report, which identifies essential elements of national and international scientific governance and oversight.

Comparative Legal Frameworks for Pre Implantation Embryonic Genetic Interventions Book

Comparative Legal Frameworks for Pre Implantation Embryonic Genetic Interventions


  • Author : Pin Lean Lau
  • Publisher : Springer
  • Release Date : 2019-08-01
  • Genre: Law
  • Pages : 326
  • ISBN 10 : 9783030223083

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Comparative Legal Frameworks for Pre Implantation Embryonic Genetic Interventions Excerpt :

This book discusses the possibilities for the use of ​international human rights law ​(and specifically, international biomedical laws related to the protection of human rights and the human genome) to provide a guiding framework for the future regulation of genetic modifications applied to human embryos and other precursor materials, when these are made with the aim of implanting a genetically altered embryo in a woman. The significance and timeliness of the work derives from the recent availability of CRISPR/​Cas9 and other gene editing tools, and from lacunae in international law regarding the legality of embryo modification with these tools and appropriate governance structures for the oversight of resulting practices. The emergence of ​improved genome editing tools like CRISPR/Cas9, holds the promise of eradicating genetic diseases in the near future. But its possible future applications with Pre-Implantation Genetic Diagnosis (PGD) raises a plethora of legal and ethical concerns about "remaking" future human beings. The work aims to address an urgent call, to embed these rising concerns about biomedical advancements into the fundamental tailoring of legal systems. Suitable regulatory approaches, coupled with careful reflection of global biomedical laws and individual constitutional systems must be explored. The Book analyzes the impact of reproductive biomedical technologies on the legal and ethical dimensions of regulatory frameworks in selected constitutional systems like the US, the UK, Australia, Malaysia and Thailand. Employing a comparative law methodology, the work reveals a dynamic intersection between legal cultures, socio-philosophical reasoning and the development of a human rights-based framework in bio-political studies. Navigating towards a truly internationalized biomedical approach to emerging technologies, it presents an understanding why a renegotiation and reinvigoration of a contemporary and "new" universal shared values system in t

Human Preimplantation Embryo Selection Book

Human Preimplantation Embryo Selection


  • Author : Jacques Cohen
  • Publisher : CRC Press
  • Release Date : 2007-09-26
  • Genre: Medical
  • Pages : 384
  • ISBN 10 : 9780203089712

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Human Preimplantation Embryo Selection Excerpt :

The most profound dilemma in assisted reproduction to date is the inability to recognize potentially viable embryos before their replacement into the reproductive tract. Application of increasingly advanced new technology has allowed the field of embryo evaluation to evolve rapidly and dramatically over the past five years.Human Preimplantation Emb

Born and Made Book

Born and Made


  • Author : Sarah Franklin
  • Publisher : Princeton University Press
  • Release Date : 2006-10-30
  • Genre: Social Science
  • Pages : 283
  • ISBN 10 : 9781400835423

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Born and Made Excerpt :

Are new reproductive and genetic technologies racing ahead of a society that is unable to establish limits to their use? Have the "new genetics" outpaced our ability to control their future applications? This book examines the case of preimplantation genetic diagnosis (PGD), the procedure used to prevent serious genetic disease by embryo selection, and the so-called "designer baby" method. Using detailed empirical evidence, the authors show that far from being a runaway technology, the regulation of PGD over the past fifteen years provides an example of precaution and restraint, as well as continual adaptation to changing social circumstances. Through interviews, media and policy analysis, and participant observation at two PGD centers in the United Kingdom, Born and Made provides an in-depth sociological examination of the competing moral obligations that define the experience of PGD. Among the many novel findings of this pathbreaking ethnography of reproductive biomedicine is the prominence of uncertainty and ambivalence among PGD patients and professionals--a finding characteristic of the emerging "biosociety," in which scientific progress is inherently paradoxical and contradictory. In contrast to much of the speculative futurology that defines this field, Born and Made provides a timely and revealing case study of the on-the-ground decision-making that shapes technological assistance to human heredity.

Assisted Conception  Research  Ethics and Law Book

Assisted Conception Research Ethics and Law


  • Author : Jennifer Gunning
  • Publisher : Routledge
  • Release Date : 2017-11-01
  • Genre: Social Science
  • Pages : 226
  • ISBN 10 : 9781351723305

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Assisted Conception Research Ethics and Law Excerpt :

This title was first published in 2003. Assisted conception is an area where it often seems that all the ethical and legal issues have been covered and then technology advances and the discussions start all over again. The book is an anthology of papers presented during a project looking at thearaputic research in assisted conception (TRAC). It is divided into three areas addressing research, ethics and law. Each chapter begins with an overview of the issues, with the aim being to present new perspectives rather than covering old ground. The European Convention on Human rights and Biomedicine came into force on December 1, 1999. The Convention allows thearaputic research and research on spare embryos but forbid fundamental research, which may be essential to the safe development of new techniques. This also means that people may become part of an experimental process without their consent. The project brings together clinicians, embryologists, lawyers and ethicists to ascertain whether there might be a risk of infertility patients being exposed to insufficiently tested procedures and to see if there is a need for fundamental research in this area. It also looks at the legislative safeguards that exist and whether a European standard for treatment should be set.

The End of Sex and the Future of Human Reproduction Book

The End of Sex and the Future of Human Reproduction


  • Author : Henry T. Greely
  • Publisher : Harvard University Press
  • Release Date : 2016-05-30
  • Genre: Law
  • Pages : 381
  • ISBN 10 : 9780674728967

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The End of Sex and the Future of Human Reproduction Excerpt :

Within twenty, maybe forty, years most people in developed countries will stop having sex for the purpose of reproduction. Instead, prospective parents will be told as much as they wish to know about the genetic makeup of dozens of embryos, and they will pick one or two for implantation, gestation, and birth. And it will be safe, lawful, and free. In this work of prophetic scholarship, Henry T. Greely explains the revolutionary biological technologies that make this future a seeming inevitability and sets out the deep ethical and legal challenges humanity faces as a result. “Readers looking for a more in-depth analysis of human genome modifications and reproductive technologies and their legal and ethical implications should strongly consider picking up Greely’s The End of Sex and the Future of Human Reproduction...[It has] the potential to empower readers to make informed decisions about the implementation of advancements in genetics technologies.” —Dov Greenbaum, Science “[Greely] provides an extraordinarily sophisticated analysis of the practical, political, legal, and ethical implications of the new world of human reproduction. His book is a model of highly informed, rigorous, thought-provoking speculation about an immensely important topic.” —Glenn C. Altschuler, Psychology Today

Rethinking Reprogenetics Book

Rethinking Reprogenetics


  • Author : Inmaculada de Melo-Martín
  • Publisher : Oxford University Press
  • Release Date : 2016-11-01
  • Genre: Uncategoriezed
  • Pages : 304
  • ISBN 10 : 9780190460204

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Rethinking Reprogenetics Excerpt :

Reprogenetic technologies, which combine the power of reproductive techniques with the tools of genetic science and technology, promise prospective parents a remarkable degree of control to pick and choose the likely characteristics of their offspring. Not only can they select embryos with or without particular genetically-related diseases and disabilities but also choose embryos with non-disease related traits such as sex. Prominent authors such as Agar, Buchanan, DeGrazia, Green, Harris, Robertson, Savulescu, and Silver have flocked to the banner of reprogenetics. For them, increased reproductive choice and reduced suffering through the elimination of genetic disease and disability are just the first step. They advocate use of these technologies to create beings who enjoy longer and healthier lives, possess greater intellectual capacities, and are capable of more refined emotional experiences. Indeed, Harris and Savulescu in particular take reprogenetic technologies to be so valuable to human beings that they have insisted that their use is not only morally permissible but morally required. Rethinking Reprogenetics challenges this mainstream view with a contextualised, gender-attentive philosophical perspective. De Melo-Martin demonstrates that you do not have to be a Luddite, social conservative, or religious zealot to resist the siren song of reprogenetics. Pointing out the flawed nature of the arguments put forward by the technologies' proponents, Rethinking Reprogenetics reveals the problematic nature of the assumptions underpinning current evaluations of these technologies and offers a framework for a more critical and sceptical assessment. "

Reproductive Technology Book

Reproductive Technology


  • Author : Jon Sterngass
  • Publisher : Cavendish Square Publishing, LLC
  • Release Date : 2012-01-15
  • Genre: Juvenile Nonfiction
  • Pages : 112
  • ISBN 10 : 9781608706464

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Reproductive Technology Excerpt :

Allows readers to use critical thinking to create informed opinions on where they stand on the issue of reproductive technology.

The Future of Human Nature Book
Score: 4
From 1 Ratings

The Future of Human Nature


  • Author : Jürgen Habermas
  • Publisher : John Wiley & Sons
  • Release Date : 2014-10-15
  • Genre: Philosophy
  • Pages : 136
  • ISBN 10 : 9780745694115

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The Future of Human Nature Excerpt :

Recent developments in biotechnology and genetic research are raising complex ethical questions concerning the legitimate scope and limits of genetic intervention. As we begin to contemplate the possibility of intervening in the human genome to prevent diseases, we cannot help but feel that the human species might soon be able to take its biological evolution in its own hands. ‘Playing God’ is the metaphor commonly used for this self-transformation of the species, which, it seems, might soon be within our grasp. In this important new book, Jürgen Habermas – the most influential philosopher and social thinker in Germany today – takes up the question of genetic engineering and its ethical implications and subjects it to careful philosophical scrutiny. His analysis is guided by the view that genetic manipulation is bound up with the identity and self-understanding of the species. We cannot rule out the possibility that knowledge of one’s own hereditary factors may prove to be restrictive for the choice of an individual’s way of life and may undermine the symmetrical relations between free and equal human beings. In the concluding chapter – which was delivered as a lecture on receiving the Peace Prize of the German Book Trade for 2001 – Habermas broadens the discussion to examine the tension between science and religion in the modern world, a tension which exploded, with such tragic violence, on September 11th.

Screening the Single Euploid Embryo Book

Screening the Single Euploid Embryo


  • Author : E Scott Sills
  • Publisher : Springer
  • Release Date : 2015-09-07
  • Genre: Health & Fitness
  • Pages : 393
  • ISBN 10 : 9783319168920

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Screening the Single Euploid Embryo Excerpt :

Intended for readers with a background in fertility medicine as well as those less familiar with IVF, this comprehensive work presents an update on preimplantation genetic testing to enable single embryo transfer (SET). An international cast of contributors explains the treatment sequence—from ovulation induction to luteal support—aiming to transfer only one euploid embryo. Applications of molecular techniques for gamete and embryo assessment are fully detailed, with a focus on the strengths and limitations of each. In addition, expert commentary is shared across a range of regulatory challenges associated with embryo screening and cryopreservation. As access to advanced reproductive technology increases against a sharper background of healthcare reform, clinicians, economists, bioethicists and legislators alike will find this new volume relevant and highly accessible.

Reproductive Genetics Book

Reproductive Genetics


  • Author : Sean Kehoe
  • Publisher : RCOG
  • Release Date : 2009-11
  • Genre: Medical
  • Pages : 242
  • ISBN 10 : 9781906985165

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Reproductive Genetics Excerpt :

This book presents the findings of the RCOG Study Group findings on genetics underlying reproductive function.

Human Gametes and Preimplantation Embryos Book

Human Gametes and Preimplantation Embryos


  • Author : David K. Gardner
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-05-27
  • Genre: Health & Fitness
  • Pages : 306
  • ISBN 10 : 9781461466512

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Human Gametes and Preimplantation Embryos Excerpt :

In recent years, the advancing science and increasing availability of assisted reproduction have given new hope to infertile couples. However, the use of IVF and ART has also led to marked increases in the number of multiple-infant live births. This poses a public health concern, as these neonates have a higher rate of pre-term delivery, compromising their survival chances and increasing their risk of lifelong disability. By optimizing the selection of gametes and embryos with high probabilities of implantation, it is possible to reduce the number of embryos transferred and, by extension, the number of high-risk multiple gestations, while maintaining or increasing pregnancy rates. Human Gametes and Preimplantation Embryos: Assessment and Diagnosis provides a broad yet concise overview of established and developing methodologies for assessment of gamete and embryo viability in assisted reproduction. This book elucidates the best practices for precisely selecting viable specimens based on morphology and cleavage rate and covers the spectrum of emerging adjunctive technologies for predicting reproductive potential. The authors present their extensive knowledge of “omics” approaches (genomics, transcriptomics, proteomics, and metabolomics), with unbiased delineation of the associated advantages and potential pitfalls. This valuable clinical resource is well suited to infertility specialists, Ob/Gyn physicians, IVF laboratory technicians, and researchers in the fields of embryology and reproductive medicine.

Contested Reproduction Book

Contested Reproduction


  • Author : John H. Evans
  • Publisher : University of Chicago Press
  • Release Date : 2010-10-15
  • Genre: Social Science
  • Pages : 280
  • ISBN 10 : 9780226222707

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Contested Reproduction Excerpt :

Scientific breakthroughs have led us to a point where soon we will be able to make specific choices about the genetic makeup of our offspring. In fact, this reality has arrived—and it is only a matter of time before the technology becomes widespread. Much like past arguments about stem-cell research, the coming debate over these reproductive genetic technologies (RGTs) will be both political and, for many people, religious. In order to understand how the debate will play out in the United States, John H. Evans conducted the first in-depth study of the claims made about RGTs by religious people from across the political spectrum, and Contested Reproduction is the stimulating result. Some of the opinions Evans documents are familiar, but others—such as the idea that certain genetic conditions produce a “meaningful suffering” that is, ultimately, desirable—provide a fascinating glimpse of religious reactions to cutting-edge science. Not surprisingly, Evans discovers that for many people opinion on the issue closely relates to their feelings about abortion, but he also finds a shared moral language that offers a way around the unproductive polarization of the abortion debate and other culture-war concerns. Admirably evenhanded, Contested Reproduction is a prescient, profound look into the future of a hot-button issue.

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine Book

Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine


  • Author : Carlos Simón
  • Publisher : CRC Press
  • Release Date : 2017-12-14
  • Genre: Medical
  • Pages : 193
  • ISBN 10 : 9781498763318

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Handbook of New Genetic Diagnostic Technologies in Reproductive Medicine Excerpt :

Different genetic diagnostic and treatment options are used worldwide to improve routine IVF procedures for the benefit of patients. This handbook updates the new genetic diagnostic technologies that have been translated to practice aiming to improve outcomes in the clinic and have a healthy baby at home. Chapters cover the use of genetic technologies in a personalized manner to unravel the possible genetic risks for the couple wishing to conceive, in terms of sperm, the embryo, the endometrium, miscarriage, and finally the fetus.