Immunological Implications and Molecular Diagnostics of Genitourinary Cancer Book

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer


  • Author : Moulay Mustapha Ennaji
  • Publisher : Academic Press
  • Release Date : 2022-10-07
  • Genre: Medical
  • Pages : 500
  • ISBN 10 : 9780323854979

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Immunological Implications and Molecular Diagnostics of Genitourinary Cancer Excerpt :

Immunological Implications and Molecular Diagnostics of Genitourinary Cancer updates on recent accomplishments, unifying concepts, and future challenges in the study of tumor-associated immune cells, emphasizing genitourinary cancers. The presence of inflammatory immune cells in human tumors raise a fundamental question: How do cancer cells avoid destruction by immune attack? In principle, tumor development can be controlled by cytotoxic innate and adaptive immune cells, however, as tumors develop from neoplastic tissue to clinically detectable tumors, cancer cells evolve different mechanisms. This book covers research on the immunological implications of genitourinary cancer with a comprehensive view, especially surrounding diagnosis and cellular mechanisms. Discusses the impact of the immune system on the initiation, progression and treatment of cancer Provides insights on the important role of the suppressor genes and oncogenes in genitourinary cancers Shows the advantages of combining clinical issues of urologic cancers with immunological techniques, like immunohistochemistry and immunofluorescence Demonstrates the implications genitourinary cancer has on the human innate immune system

Directory of Pathology Training Programs in the United States and Canada Book

Directory of Pathology Training Programs in the United States and Canada


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2008
  • Genre: Medicine
  • Pages : null
  • ISBN 10 : CHI:76992348

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Directory of Pathology Training Programs in the United States and Canada Excerpt :

Directory intended to give "medical students and graduate physicians a timely source of detailed information about the many options for pathology training in the United States and Canada." Geographical arrangement. Entries give in narrative such information as programs offered, facilities, community environment, stipends, staff, and application. Training staff index.

Genitourinary Cancers Book

Genitourinary Cancers


  • Author : Siamak Daneshmand
  • Publisher : Springer
  • Release Date : 2018-08-31
  • Genre: Medical
  • Pages : 308
  • ISBN 10 : 9783319933399

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Genitourinary Cancers Excerpt :

This book addresses the most pressing current questions in the management of urologic malignancies. The rapid advances in imaging and molecular markers are placed into a clinical context, with explanation of their effects on prognosis and treatment planning. Similarly, progress in immunotherapy is carefully examined, focusing in particular on the role of immune checkpoint inhibitors in both early- and late-stage urologic malignancies. Looking beyond the improvements in minimally invasive techniques for urologic cancers, the impacts of care coordination pathways and enhanced recovery after surgery protocols are reviewed. Readers will also find enlightening discussion of the decision algorithm for the treatment of early-stage, high-grade bladder cancer, taking into account evidence on the most advanced treatment options and the circumstances in which surgery may need to be expedited. The penultimate chapter discusses the Cancer Genome Atlas project for bladder cancer, and the book closes by considering contemporary medical and surgical management of testicular cancer.

Invasive Bladder Cancer Book

Invasive Bladder Cancer


  • Author : PierFrancesco Bassi
  • Publisher : Springer Science & Business Media
  • Release Date : 2007-07-29
  • Genre: Medical
  • Pages : 303
  • ISBN 10 : 9781846283772

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Invasive Bladder Cancer Excerpt :

Invasive bladder tumors affect the muscle wall, and have a propensity to metastasize and spread to other areas of the body, and are more likely to be fatal. This book presents state-of-the-art diagnoses and treatments available for bladder cancer that has metastasised into the body. A thorough review of current practice is presented in a full color volume with more than 40 tables and 50 illustrations. The book offers a comprehensive review of the subject, covering epidemiology, screening, diagnostic factors, surgery, chemotherapy and post-operative monitoring. Most chapters are jointly written by a basic researcher and a clinician.

Management of Muscle Invasive Bladder Cancer Book

Management of Muscle Invasive Bladder Cancer


  • Author : Sanchia S. Goonewardene
  • Publisher : Springer Nature
  • Release Date : 2021-02-02
  • Genre: Medical
  • Pages : 590
  • ISBN 10 : 9783030579159

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Management of Muscle Invasive Bladder Cancer Excerpt :

This book provides a systematic review of the management and treatment of this disease. The concise and highly structured chapters feature essential background knowledge and commentary on recent advances within each step of a range of patient pathways. Management of Muscle Invasive Bladder Cancer provides a framework for patients’ care based on the research, as well as practically and clinically oriented guidelines. This book is relevant to trainees and practicing urologists and oncologists, in addition to medical professionals involved in the treatment of bladder cancer.

Molecular Diagnostics Book

Molecular Diagnostics


  • Author : George Patrinos
  • Publisher : Elsevier
  • Release Date : 2005-06-06
  • Genre: Science
  • Pages : 488
  • ISBN 10 : 0080473504

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Molecular Diagnostics Excerpt :

Molecular Diagnostics covers current molecular biological techniques used to identify the underlying molecular defects in inherited disease. Although an increasing number of laboratories, both academic and private are moving in that direction, there are only a few books in the existing literature, and they deal only partly with diagnosis at the molecular level. Each chapter includes the principle and a brief description of the technique, followed by exmples from the authors' own epertise. Contributors are well-known experts in their field, and derive from a variety of disciplines, to ensure breadth and depth of coverage. Examines widely used molecular biology techniques to screen for genetic defects causing inherited disorders Includes state-of-the-art techniques for the detection of the underlying genetic heterogeneity leading to inherited disorders Identification of genetically modified organisms (GMO's) Forensic analysis and every-day issues in a diagnostic laboratory Discusses ethics, genetic counselling and quality management

Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers Book

Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers


  • Author : Andrea Necchi
  • Publisher : Springer Nature
  • Release Date : 2022-01-03
  • Genre: Medical
  • Pages : 315
  • ISBN 10 : 9783030805463

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Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers Excerpt :

This book aims to provide readers with a current overview of enrolling trials with immune-checkpoint inhibitors in the preoperative setting of localized bladder cancer, renal cell carcinoma, and prostate cancer. The advent of immunotherapy has revolutionized treatments of genitourinary malignancy and evolved strategies for multidisciplinary management. This book explains neoadjuvant checkpoint inhibitors in localized genitourinary cancers, providing insights into the mechanisms of response and development of resistance of cancer cells to immunotherapy. It debates optimal trial design of preoperative checkpoint inhibitors in GU tumors, including optimal endpoints and the role of pathologic response as a surrogate endpoint of survival. It also illuminates clinical management of patients with organ-confined GU tumors, such as side effect management and perioperative safety, before providing an overview of biomarker use for patient selection across the early-stage GU malignancies. Lastly, the book provides the reader with the most up-to-date data emerging from clinical trials involving immunotherapy in early-stage GU malignancies. Neoadjuvant Immunotherapy Treatment of Localized Genitourinary Cancers: Multidisciplinary Management provides a comprehensive review of the field, serving as a valuable resource for urologists, medical oncologists, pathologists, fellows in urologic oncology, upper-level residents training in urology and medical oncology, as well as pharmacists interested in RCC clinicians.

Biomarkers in Urologic Cancer  An Issue of Urologic Clinics of North America  E Book Book

Biomarkers in Urologic Cancer An Issue of Urologic Clinics of North America E Book


  • Author : Kevin R. Loughlin
  • Publisher : Elsevier Health Sciences
  • Release Date : 2016-01-19
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 9780323417198

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Biomarkers in Urologic Cancer An Issue of Urologic Clinics of North America E Book Excerpt :

The past decade has been marked by the acceleration of our understanding of the molecular biology of cancer. Simultaneously, there have been increasing exigencies to diagnose, treat and follow cancer patients more economically. Biomarkers represent the marriage of science and economics. Biomarkers offer the potential to increase the precision of diagnosis, prognosis, and surveillance of urological malignancies. This issue presents the cutting-edge advances of biomarker technology to urologic oncology.

Research Awards Index Book

Research Awards Index


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1989
  • Genre: Medicine
  • Pages : null
  • ISBN 10 : UOM:39015014022589

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Research Awards Index Excerpt :

Subject Index of Extramural Research Administered by the National Cancer Institute Book

Subject Index of Extramural Research Administered by the National Cancer Institute


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1978
  • Genre: Cancer
  • Pages : null
  • ISBN 10 : MINN:31951D03885829Q

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Subject Index of Extramural Research Administered by the National Cancer Institute Excerpt :

Current information about research grants and contracts supported by the National Cancer Institute. Subject listing gives contract or grant number and topic. Investigator, grant number, and contract number indexes.