Introduction to Modeling in Physiology and Medicine Book

Introduction to Modeling in Physiology and Medicine


  • Author : Claudio Cobelli
  • Publisher : Elsevier
  • Release Date : 2008-02-06
  • Genre: Technology & Engineering
  • Pages : 337
  • ISBN 10 : 9780080559988

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Introduction to Modeling in Physiology and Medicine Excerpt :

This unified modeling textbook for students of biomedical engineering provides a complete course text on the foundations, theory and practice of modeling and simulation in physiology and medicine. It is dedicated to the needs of biomedical engineering and clinical students, supported by applied BME applications and examples. Developed for biomedical engineering and related courses: speaks to BME students at a level and in a language appropriate to their needs, with an interdisciplinary clinical/engineering approach, quantitative basis, and many applied examples to enhance learning Delivers a quantitative approach to modeling and also covers simulation: the perfect foundation text for studies across BME and medicine Extensive case studies and engineering applications from BME, plus end-of-chapter exercises

Introduction to Modeling in Physiology and Medicine Book

Introduction to Modeling in Physiology and Medicine


  • Author : Claudio Cobelli
  • Publisher : Academic Press
  • Release Date : 2019-08
  • Genre: Uncategoriezed
  • Pages : 350
  • ISBN 10 : 0128157569

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Introduction to Modeling in Physiology and Medicine Excerpt :

This unified physiological modeling textbook is for students taking modeling and physiological courses in biomedical engineering and the biological and life sciences. It provides a complete introduction to the foundations, theory and practice of modeling and simulation in medicine, bioscience and engineering, and for clinical applications.Introduction to Modeling in Physiology and Medicine, Second Edition develops a clear understanding of the fundamental principles of good modeling methodology. Readers are shown how to create valid mathematical models that are fit for a range of purposes, supported throughout by detailed explanation, extensive case studies, examples and applications. New to this Edition: Clearer guidance is provided on the mathematical prerequisites needed to achieve the maximum benefit from the material to be found, particularly in the later chapters Greater detail regarding basic approaches to modeling is provided, particularly in the Non-linear and Stochastic Modeling sections in Chapter 5 The range of case study material has been substantially extended, with examples drawn from recent research experience Key examples include: a cellular model of insulin secretion and its extension to the whole-body level; a model of insulin action during a meal/oral glucose tolerance test; a large-scale simulation model of type 1 diabetes and its use in in silico clinical trials and drug trials Covers the underlying principles of good quantitative modeling methodology, with applied biomedical engineering and bioscience examples to ensure relevance to students, current research and clinical practice Key topics include: modeling data, modeling systems, linear and non-linear systems; model identification; parametric and non-parametric models; and model validation Clear, step-by-step working plus examples and extensive case studies relate concepts to real world applications; end of chapter exercises and assignments reinforce learning

Modelling Methodology for Physiology and Medicine Book

Modelling Methodology for Physiology and Medicine


  • Author : Ewart Carson
  • Publisher : Newnes
  • Release Date : 2013-12-05
  • Genre: Science
  • Pages : 588
  • ISBN 10 : 9780124095250

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Modelling Methodology for Physiology and Medicine Excerpt :

Modelling Methodology for Physiology and Medicine, Second Edition, offers a unique approach and an unprecedented range of coverage of the state-of-the-art, advanced modeling methodology that is widely applicable to physiology and medicine. The second edition, which is completely updated and expanded, opens with a clear and integrated treatment of advanced methodology for developing mathematical models of physiology and medical systems. Readers are then shown how to apply this methodology beneficially to real-world problems in physiology and medicine, such as circulation and respiration. The focus of Modelling Methodology for Physiology and Medicine, Second Edition, is the methodology that underpins good modeling practice. It builds upon the idea of an integrated methodology for the development and testing of mathematical models. It covers many specific areas of methodology in which important advances have taken place over recent years and illustrates the application of good methodological practice in key areas of physiology and medicine. It builds on work that the editors have carried out over the past 30 years, working in cooperation with leading practitioners in the field. Builds upon and enhances the reader's existing knowledge of modeling methodology and practice Editors are internationally renowned leaders in their respective fields Provides an understanding of modeling methodologies that can address real problems in physiology and medicine and achieve results that are beneficial either in advancing research or in providing solutions to clinical problems

Personalized Predictive Modeling in Type 1 Diabetes Book

Personalized Predictive Modeling in Type 1 Diabetes


  • Author : Eleni I. Georga
  • Publisher : Academic Press
  • Release Date : 2017-12-11
  • Genre: Medical
  • Pages : 252
  • ISBN 10 : 9780128051467

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Personalized Predictive Modeling in Type 1 Diabetes Excerpt :

Personalized Predictive Modeling in Diabetes features state-of-the-art methodologies and algorithmic approaches which have been applied to predictive modeling of glucose concentration, ranging from simple autoregressive models of the CGM time series to multivariate nonlinear regression techniques of machine learning. Developments in the field have been analyzed with respect to: (i) feature set (univariate or multivariate), (ii) regression technique (linear or non-linear), (iii) learning mechanism (batch or sequential), (iv) development and testing procedure and (v) scaling properties. In addition, simulation models of meal-derived glucose absorption and insulin dynamics and kinetics are covered, as an integral part of glucose predictive models. This book will help engineers and clinicians to: select a regression technique which can capture both linear and non-linear dynamics in glucose metabolism in diabetes, and which exhibits good generalization performance under stationary and non-stationary conditions; ensure the scalability of the optimization algorithm (learning mechanism) with respect to the size of the dataset, provided that multiple days of patient monitoring are needed to obtain a reliable predictive model; select a features set which efficiently represents both spatial and temporal dependencies between the input variables and the glucose concentration; select simulation models of subcutaneous insulin absorption and meal absorption; identify an appropriate validation procedure, and identify realistic performance measures. Describes fundamentals of modeling techniques as applied to glucose control Covers model selection process and model validation Offers computer code on a companion website to show implementation of models and algorithms Features the latest developments in the field of diabetes predictive modeling

Modeling and Simulation in Biomedical Engineering  Applications in Cardiorespiratory Physiology Book

Modeling and Simulation in Biomedical Engineering Applications in Cardiorespiratory Physiology


  • Author : Willem van Meurs
  • Publisher : McGraw Hill Professional
  • Release Date : 2011-08-07
  • Genre: Technology & Engineering
  • Pages : 224
  • ISBN 10 : 9780071714464

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Modeling and Simulation in Biomedical Engineering Applications in Cardiorespiratory Physiology Excerpt :

THEORY AND PRACTICE OF MODELING AND SIMULATING HUMAN PHYSIOLOGY Written by a coinventor of the Human Patient Simulator (HPS) and past president of the Society in Europe for Simulation Applied to Medicine (SESAM), Modeling and Simulation in Biomedical Engineering: Applications in Cardiorespiratory Physiology is a compact and consistent introduction to this expanding field. The book divides the modeling and simulation process into five manageable steps--requirements, conceptual models, mathematical models, software implementation, and simulation results and validation. A framework and a basic set of deterministic, continuous-time models for the cardiorespiratory system are provided. This timely resource also addresses advanced topics, including sensitivity analysis and setting model requirements as part of an encompassing simulation and simulator design. Practical examples provide you with the skills to evaluate and adapt existing physiologic models or create new ones for specific applications. Coverage includes: Signals and systems Model requirements Conceptual models Mathematical models Software implementation Simulation results and model validation Cardiorespiratory system model Circulation Respiration Physiologic control Sensitivity analysis of a cardiovascular model Design of model-driven acute care training simulators “Uniquely qualified to author such a text, van Meurs is one of the original developers of CAE Healthcare’s Human Patient Simulator (HPS). ...His understanding of mathematics, human physiology, pharmacology, control systems, and systems engineering, combined with a conversational writing style, results in a readable text. ...The ample illustrations and tables also break up the text and make reading the book easier on the eyes. ...concise yet in conversational style, with real-life examples. This book is highly recommended for coursework in physiologic modeling and for all who are interested in simulator design and development. The book pulls all

Military Quantitative Physiology Book

Military Quantitative Physiology


  • Author : Karl Friedl
  • Publisher : Department of the Army
  • Release Date : 2012
  • Genre: Medical
  • Pages : 438
  • ISBN 10 : MINN:31951D03536518H

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Military Quantitative Physiology Excerpt :

NOTE: NO FURTHER DISCOUNT FOR THIS PRINT PRODUCT- OVERSTOCK SALE -- Significantly reduced list price Few human activities demand or deserve as much attention of the citizens of a nation as the array of man-made and natural "environmental" threats faced by the soldiers and other warriors defending the nation - those that pose the risk of disease, injury, combat wounds, and even death. This book is the Army's first detailing research in computational physiology models and highlighting pivotal research. It outlines the extent to which basic and applied biomedical scientists, clinicians, modelers, and others stribe to understand the extent of these threats, and provide intellectual and materiel options to mitigate these risks. This book summarizes major Army research efforts to quantify and model military relevant physiology. These chapters highlight the translation of this research into useful predictive tools. The tools are of importance to medical planners, materiel developers, commanders, and in many cases, every soldier. These chapters detail the experimental basis for many of the predictive tools that are currently in use. This book is written for military clinicians, and medical researchers who may be reasonably expected to explain some of the background, as well as those who will extend the research. Many people will find this book interesting because it details research on topics that affect everyone in everyday life, including how we sleep, eat, and exercise, as well as more specific topics such as the effects of caffeine on performance, risks associated with laser pointers, and even Army blast models that have influenced safety thresholds for car airbag deployments.

Control Theory in Biomedical Engineering Book

Control Theory in Biomedical Engineering


  • Author : Olfa Boubaker
  • Publisher : Academic Press
  • Release Date : 2020-06-30
  • Genre: Science
  • Pages : 396
  • ISBN 10 : 9780128226216

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Control Theory in Biomedical Engineering Excerpt :

Control Theory in Biomedical Engineering: Applications in Physiology and Medical Robotics highlights the importance of control theory and feedback control in our lives and explains how this theory is central to future medical developments. Control theory is fundamental for understanding feedback paths in physiological systems (endocrine system, immune system, neurological system) and a concept for building artificial organs. The book is suitable for graduate students and researchers in the control engineering and biomedical engineering fields, and medical students and practitioners seeking to enhance their understanding of physiological processes, medical robotics (legs, hands, knees), and controlling artificial devices (pacemakers, insulin injection devices). Control theory profoundly impacts the everyday lives of a large part of the human population including the disabled and the elderly who use assistive and rehabilitation robots for improving the quality of their lives and increasing their independence. Gives an overview of state-of-the-art control theory in physiology, emphasizing the importance of this theory in the medical field through concrete examples, e.g., endocrine, immune, and neurological systems Takes a comprehensive look at advances in medical robotics and rehabilitation devices and presents case studies focusing on their feedback control Presents the significance of control theory in the pervasiveness of medical robots in surgery, exploration, diagnosis, therapy, and rehabilitation

Introduction to Biomedical Engineering Book

Introduction to Biomedical Engineering


  • Author : John Enderle
  • Publisher : Elsevier
  • Release Date : 2005-05-20
  • Genre: Science
  • Pages : 1144
  • ISBN 10 : 9780080473147

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Introduction to Biomedical Engineering Excerpt :

Under the direction of John Enderle, Susan Blanchard and Joe Bronzino, leaders in the field have contributed chapters on the most relevant subjects for biomedical engineering students. These chapters coincide with courses offered in all biomedical engineering programs so that it can be used at different levels for a variety of courses of this evolving field. Introduction to Biomedical Engineering, Second Edition provides a historical perspective of the major developments in the biomedical field. Also contained within are the fundamental principles underlying biomedical engineering design, analysis, and modeling procedures. The numerous examples, drill problems and exercises are used to reinforce concepts and develop problem-solving skills making this book an invaluable tool for all biomedical students and engineers. New to this edition: Computational Biology, Medical Imaging, Genomics and Bioinformatics. * 60% update from first edition to reflect the developing field of biomedical engineering * New chapters on Computational Biology, Medical Imaging, Genomics, and Bioinformatics * Companion site: http://intro-bme-book.bme.uconn.edu/ * MATLAB and SIMULINK software used throughout to model and simulate dynamic systems * Numerous self-study homework problems and thorough cross-referencing for easy use

Signals and Systems in Biomedical Engineering Book

Signals and Systems in Biomedical Engineering


  • Author : Suresh R. Devasahayam
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Technology & Engineering
  • Pages : 333
  • ISBN 10 : 9781461542995

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Signals and Systems in Biomedical Engineering Excerpt :

In the past few years Biomedical Engineering has received a great deal of attention as one of the emerging technologies in the last decade and for years to come, as witnessed by the many books, conferences, and their proceedings. Media attention, due to the applications-oriented advances in Biomedical Engineering, has also increased. Much of the excitement comes from the fact that technology is rapidly changing and new technological adventures become available and feasible every day. For many years the physical sciences contributed to medicine in the form of expertise in radiology and slow but steady contributions to other more diverse fields, such as computers in surgery and diagnosis, neurology, cardiology, vision and visual prosthesis, audition and hearing aids, artificial limbs, biomechanics, and biomaterials. The list goes on. It is therefore hard for a person unfamiliar with a subject to separate the substance from the hype. Many of the applications of Biomedical Engineering are rather complex and difficult to understand even by the not so novice in the field. Much of the hardware and software tools available are either too simplistic to be useful or too complicated to be understood and applied. In addition, the lack of a common language between engineers and computer scientists and their counterparts in the medical profession, sometimes becomes a barrier to progress.

Mathematics in Medicine and the Life Sciences Book

Mathematics in Medicine and the Life Sciences


  • Author : Frank C. Hoppensteadt
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-03-09
  • Genre: Mathematics
  • Pages : 252
  • ISBN 10 : 9781475741315

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Mathematics in Medicine and the Life Sciences Excerpt :

The aim of this book is to introduce the subject of mathematical modeling in the life sciences. It is intended for students of mathematics, the physical sciences, and engineering who are curious about biology. Additionally, it will be useful to students of the life sciences and medicine who are unsatisfied with mere description and who seek an understanding of biological mechanism and dynamics through the use of mathematics. The book will be particularly useful to premedical students, because it will introduce them not only to a collection of mathematical methods but also to an assortment of phenomena involving genetics, epidemics, and the physiology of the heart, lung, and kidney. Because of its introductory character, mathematical prerequisites are kept to a minimum; they involve only what is usually covered in the first semester of a calculus sequence. The authors have drawn on their extensive experience as modelers to select examples which are simple enough to be understood at this elementary level and yet realistic enough to capture the essence of significant biological phenomena drawn from the areas of population dynamics and physiology. Because the models presented are realistic, the book can serve not only as an introduction to mathematical methods but also as a mathematical introduction to the biological material itself. For the student, who enjoys mathematics, such an introduction will be far more stimulating and satisfying than the purely descriptive approach that is traditional in the biological sciences.

Applied Mathematical Models in Human Physiology Book

Applied Mathematical Models in Human Physiology


  • Author : Johnny T. Ottesen
  • Publisher : SIAM
  • Release Date : 2004-01-01
  • Genre: Medical
  • Pages : 311
  • ISBN 10 : 0898718287

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Applied Mathematical Models in Human Physiology Excerpt :

This book introduces mathematicians to real applications from physiology. Using mathematics to analyze physiological systems, the authors focus on models reflecting current research in cardiovascular and pulmonary physiology. In particular, they present models describing blood flow in the heart and the cardiovascular system, as well as the transport of oxygen and carbon dioxide through the respiratory system and a model for baroreceptor regulation.

Investigating Biological Systems Using Modeling Book

Investigating Biological Systems Using Modeling


  • Author : Meryl E. Wastney
  • Publisher : Academic Press
  • Release Date : 2012-12-02
  • Genre: Computers
  • Pages : 382
  • ISBN 10 : 9780080926452

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Investigating Biological Systems Using Modeling Excerpt :

Investigating Biological Systems Using Modeling describes how to apply software to analyze and interpret data from biological systems. It is written for students and investigators in lay person's terms, and will be a useful reference book and textbook on mathematical modeling in the design and interpretation of kinetic studies of biological systems. It describes the mathematical techniques of modeling and kinetic theory, and focuses on practical examples of analyzing data. The book also uses examples from the fields of physiology, biochemistry, nutrition, agriculture, pharmacology, and medicine. Contains practical descriptions of how to analyze kinetic data Provides examples of how to develop and use models Describes several software packages including SAAM/CONSAM Includes software with working models

Nonlinear Dynamics in Physiology and Medicine Book

Nonlinear Dynamics in Physiology and Medicine


  • Author : Anne Beuter
  • Publisher : Springer Science & Business Media
  • Release Date : 2013-06-05
  • Genre: Mathematics
  • Pages : 436
  • ISBN 10 : 9780387216409

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Nonlinear Dynamics in Physiology and Medicine Excerpt :

Introduces concepts from nonlinear dynamics using an almost exclusively biological setting for motivation, and includes examples of how these concepts are used in experimental investigations of biological and physiological systems. One novel feature of the book is the inclusion of classroom-tested computer exercises. This book will appeal to students and researchers working in the natural and physical sciences wanting to learn about physiological systems from a mathematical perspective.

Modeling and Simulation in Medicine and the Life Sciences Book

Modeling and Simulation in Medicine and the Life Sciences


  • Author : Frank C. Hoppensteadt
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-12-06
  • Genre: Mathematics
  • Pages : 355
  • ISBN 10 : 9780387215716

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Modeling and Simulation in Medicine and the Life Sciences Excerpt :

The result of lectures given by the authors at New York University, the University of Utah, and Michigan State University, the material is written for students who have had only one term of calculus, but it contains material that can be used in modeling courses in applied mathematics at all levels through early graduate courses. Numerous exercises are given as well as solutions to selected exercises, so as to lead readers to discover interesting extensions of that material. Throughout, illustrations depict physiological processes, population biology phenomena, corresponding models, and the results of computer simulations. Topics covered range from population phenomena to demographics, genetics, epidemics and dispersal; in physiological processes, including the circulation, gas exchange in the lungs, control of cell volume, the renal counter-current multiplier mechanism, and muscle mechanics; to mechanisms of neural control. Each chapter is graded in difficulty, so a reading of the first parts of each provides an elementary introduction to the processes and their models.

Advances in Biomedical Engineering Book
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Advances in Biomedical Engineering


  • Author : Pascal Verdonck
  • Publisher : Elsevier
  • Release Date : 2008-09-11
  • Genre: Technology & Engineering
  • Pages : 320
  • ISBN 10 : 0080932088

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Advances in Biomedical Engineering Excerpt :

The aim of this essential reference is to bring together the interdisciplinary areas of biomedical engineering education. Contributors review the latest advances in biomedical engineering research through an educational perspective, making the book useful for students and professionals alike. Topics range from biosignal analysis and nanotechnology to biophotonics and cardiovascular medical devices. - Provides an educational review of recent advances - Focuses on biomedical high technology - Features contributions from leaders in the field