Recent Advances in iPSC Derived Cell Types Book

Recent Advances in iPSC Derived Cell Types


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-02-21
  • Genre: Science
  • Pages : 282
  • ISBN 10 : 9780128224540

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Recent Advances in iPSC Derived Cell Types Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells. Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cellular populations, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs to derive different cell types, such as: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine and therapeutics. Covers the following cell types derived from iPSCs: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. Contributions from st

Current Progress in iPSC derived Cell Types Book

Current Progress in iPSC derived Cell Types


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-06-02
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780128238851

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Current Progress in iPSC derived Cell Types Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells can be differentiated into different cell types. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how research of induced pluripotent stem cells can be reprogrammed to develop new treatment technologies in regenerative medicine. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived cardiomyocytes, skeletal muscles, brown adipocytes, airway epithelial cells, and much more Contributed by world-renown experts in the field

Novel Concepts in iPSC Disease Modeling Book

Novel Concepts in iPSC Disease Modeling


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2022-01-25
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780128238837

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Novel Concepts in iPSC Disease Modeling Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. iPSCs - Novel Concepts, Volume 15 addresses how important induced pluripotent stems cells are and how can they can help treat certain diseases. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how induced pluripotent stem cells are being used for treatment of different disorders, such as liver disease, type-1 diabetes, Parkinson’s disease, macular degeneration of the retina and much more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers spinal cord injuries, type-1 diabetes, liver disease, Parkinson’s disease, graft vs. host disease, and much more Contributed by world-renown experts in the field

Current Progress in IPSC derived Cell Types Book

Current Progress in IPSC derived Cell Types


  • Author : Alexander Birbrair
  • Publisher : Elsevier
  • Release Date : 2021-06-09
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9780128238844

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Current Progress in IPSC derived Cell Types Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Current Progress in iPSC-derived Cell Types, Volume 10 addresses how induced pluripotent stem cells can be differentiated into different cell types. Somatic cells can be reprogrammed into induced pluripotent stem cells by the expression of specific transcription factors. These cells have been transforming biomedical research over the last 15 years. This volume will address the advances in research of how research of induced pluripotent stem cells can be reprogrammed to develop new treatment technologies in regenerative medicine. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived cardiomyocytes, skeletal muscles, brown adipocytes, airway epithelial cells, and much more Contributed by world-renown experts in the field

Cell Sources for iPSCs  Volume 7 Book

Cell Sources for iPSCs Volume 7


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-05-21
  • Genre: Science
  • Pages : 280
  • ISBN 10 : 9780128223277

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Cell Sources for iPSCs Volume 7 Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Cell Sources for IPSCs, Volume 7 address how important are cancer stem cells within the cancer development, and how can we target those cells to try to stop this disease. Cancer cells depend on cancer stem cells to appear, reactivate and grow. As each cancer is a different disease, this book will discuss the role of cancer stem cells in many different cancers. This book will provide an overview of various cancer such as: melanoma, glioblastoma, thyroid carcinoma, colon cancer, head and neck squamous cell carcinoma, osteosarcoma and more. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers the following cancers: melanoma, glioblastoma, thyroid carcinoma, colon cancer, and much more Contributed by world-renowned experts in the field

Recent Advances in iPSC Derived Cell Types  Volume 4 Book

Recent Advances in iPSC Derived Cell Types Volume 4


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2021-03-11
  • Genre: Science
  • Pages : 282
  • ISBN 10 : 9780128222300

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Recent Advances in iPSC Derived Cell Types Volume 4 Excerpt :

The series Advances in Stem Cell Biology is a timely and expansive collection of comprehensive information and new discoveries in the field of stem cell biology. Recent Advances in iPSC-derived Cell Types, Volume 4 addresses how different cell types can be derived from induced pluripotent stem cells. Somatic cells can be reprogrammed into Induced pluripotent stem cells by the expression of specific transcription factors. These cells are transforming biomedical research in the last 15 years. The volume teaches readers about current advances in the field. This book describes the use of induced pluripotent stem cells to form different cell types which can be used in cell therapy as well as to model several diseases in vitro, enabling us to study the cellular and molecular mechanisms involved in different pathologies. In recent years, remarkable progress has been made in the obtention of induced pluripotent stem cells and their differentiation into several cellular populations, tissues and organs using state-of-art techniques. This volume will cover what we know so far about the use of iPSCs to derive different cell types, such as: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ßpancreatic cells, and more. The volume is written for researchers and scientists interested in stem cell therapy, cell biology, regenerative medicine, and organ transplantation; and is contributed by world-renowned authors in the field. Provides overview of the fast-moving field of induced pluripotent stem cell technology, regenerative medicine and therapeutics. Covers the following cell types derived from iPSCs: erythroid cells, mucosal-associated invariant T cells, megakaryocytes, cerebral cortical neurons, inner ear cell types, airway epithelial cells, male germ cells, trophoblasts, cardiomyocytes, ?pancreatic cells, and more. Contributions from ste

Pluripotent Stem Cells Book

Pluripotent Stem Cells


  • Author : Minoru Tomizawa
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-07-20
  • Genre: Science
  • Pages : 534
  • ISBN 10 : 9789535124719

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Pluripotent Stem Cells Excerpt :

Pluripotent stem cells have distinct characteristics: self-renewal and the potential to differentiate into various somatic cells. In recent years, substantial advances have been made from basic science to clinical applications. The vast amount knowledge available makes obtaining concise yet sufficient information difficult, hence the purpose of this book. In this book, embryonic stem cells, induced pluripotent stem cells, and mesenchymal stem cells are discussed. The book is divided into five sections: pluripotency, culture methods, toxicology, disease models, and regenerative medicine. The topics covered range from new concepts to current technologies. Readers are expected to gain useful information from expert contributors.

Phenotyping of Human iPSC derived Neurons Book

Phenotyping of Human iPSC derived Neurons


  • Author : Elizabeth D. Buttermore
  • Publisher : Academic Press
  • Release Date : 2022-09-30
  • Genre: Medical
  • Pages : 374
  • ISBN 10 : 9780128222782

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Phenotyping of Human iPSC derived Neurons Excerpt :

Phenotyping of Human iPSC-derived Neurons: Patient-Driven Research examines the steps in a preclinical pipeline that utilizes iPSC-derived neuronal technology to better understand neurological disorders and identify novel therapeutics, also providing considerations and best practices. By presenting example projects that identify phenotypes and mechanisms relevant to autism spectrum disorder and epilepsy, this book allows readers to understand what considerations are important to assess at the start of project design. Sections address reproducibility issues and advances in technology at each stage of the pipeline and provide suggestions for improvement. From patient sample collection and proper controls to neuronal differentiation, phenotyping, screening, and considerations for moving to the clinic, these detailed descriptions of each stage of the pipeline will help everyone, regardless of stage in the pipeline. In recent years, drug discovery in the neurosciences has struggled to identify novel therapeutics for patients with varying indications, including epilepsy, chronic pain, and psychosis. Current treatment options for such patients are decades old and offer little relief with many side effects. One explanation for this lull in novel therapeutics is a lack of novel target identification for neurological disorders (and target identification requires exemplar preclinical data). To improve on the preclinical work that often relies on rodent modeling, the field has begun utilizing patient-derived induced pluripotent stem cells (iPSCs) to differentiate neurons in vitro for preclinical characterization of neurological disease and target identification. Discusses techniques and new technology for iPSC culturing and neuronal differentiation to establish best practices in the lab Outlines considerations for phenotypic assay development Provides information about the successes, failures, and implications of phenotyping and screening with iPSC-derived neurons Describes how

Human Embryonic Stem Cells Book

Human Embryonic Stem Cells


  • Author : Arlene Chiu
  • Publisher : Springer Science & Business Media
  • Release Date : 2003-08-01
  • Genre: Science
  • Pages : 455
  • ISBN 10 : 9781592594238

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Human Embryonic Stem Cells Excerpt :

A discussion of all the key issues in the use of human pluripotent stem cells for treating degenerative diseases or for replacing tissues lost from trauma. On the practical side, the topics range from the problems of deriving human embryonic stem cells and driving their differentiation along specific lineages, regulating their development into mature cells, and bringing stem cell therapy to clinical trials. Regulatory issues are addressed in discussions of the ethical debate surrounding the derivation of human embryonic stem cells and the current policies governing their use in the United States and abroad, including the rules and conditions regulating federal funding and questions of intellectual property.

Adult Stem Cells   Advances in Research and Application  2013 Edition Book

Adult Stem Cells Advances in Research and Application 2013 Edition


  • Author : Anonim
  • Publisher : ScholarlyEditions
  • Release Date : 2013-06-21
  • Genre: Science
  • Pages : 113
  • ISBN 10 : 9781481669320

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Adult Stem Cells Advances in Research and Application 2013 Edition Excerpt :

Adult Stem Cells—Advances in Research and Application: 2013 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about ZZZAdditional Research in a concise format. The editors have built Adult Stem Cells—Advances in Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about ZZZAdditional Research in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Adult Stem Cells—Advances in Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.

iPS Cells for Modelling and Treatment of Human Diseases Book

iPS Cells for Modelling and Treatment of Human Diseases


  • Author : Michael J. Edel
  • Publisher : MDPI
  • Release Date : 2018-10-02
  • Genre: Electronic book
  • Pages : 422
  • ISBN 10 : 9783038421221

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iPS Cells for Modelling and Treatment of Human Diseases Excerpt :

This book is a printed edition of the Special Issue "iPS Cells for Modelling and Treatment of Human Diseases" that was published in JCM

iPSCs   State of the Science Book

iPSCs State of the Science


  • Author : Alexander Birbrair
  • Publisher : Academic Press
  • Release Date : 2022-01-09
  • Genre: Science
  • Pages : 316
  • ISBN 10 : 9780323856454

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iPSCs State of the Science Excerpt :

iPSCs - State of the Science, Volume Sixteen, the latest release in the Advances in Stem Cell Biology series, is an expansive collection of information and new discoveries in the field. This volume addresses the importance of induced pluripotent stems cells and how can they be derived from different sources. It addresses advances in research in induced pluripotent stem cells from alternate sources, such as spermatogonial stem cells, ovarian tissue, cancer cells, and many other sources. It is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation, and is contributed by world-renowned authors. Provides an overview of the fast-moving field of stem cell biology and function, regenerative medicine and therapeutics Covers iPSCs derived from amniotic fluid, oral tissue derived iPSCs, muse cells, postmortem tissue, and much more Contributed by world-renowned experts in the field

Stem Cells and Cancer Stem Cells  Volume 6 Book

Stem Cells and Cancer Stem Cells Volume 6


  • Author : M.A. Hayat
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-02-29
  • Genre: Medical
  • Pages : 445
  • ISBN 10 : 9789400729926

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Stem Cells and Cancer Stem Cells Volume 6 Excerpt :

The difference among pluripotent stem cells, multipotent stem cells, and unipotent stem cells is pointed out. Vast therapeutic applications of the following specific stem cells in disease and tissue injury are discussed: human embryonic stem cells, human mesenchymal stem cells, germ cell-derived pluripotent stem cells, induced pluripotent stem cells, human umbilical cord blood-derived stem cells, breast tumor stem cells,and hematopoietic stem cells. Because of the potential of human embryonic stem cells to produce unlimited quantities of any human cell type, considerable focus is placed on their therapeutic potential. Because of their pluripotency, these cells have been used in various applications such as tissue engineering, regenerative medicine, pharmacological and toxicological studies, and fundamental studies of cell differentiation. The formation of embryoid bodies, which are three-dimensional aggregates of embryonic stem cells, is explained as this is the first step in cell differentiation. Such embryoid body culture has been widely used as a trigger for the in vitro differentiation of embryonic stem cells. The basic capacity of self-renewal of human embryogenic stem cells is explained. The role of TGF-beta in the propagation of human embryonic stem cells is discussed. The differentiation of human embryonic stem cells into neurons, hepatocytes, cardiomyocytes, and retinal cells is fully explained. Donor policies for hematopoietic stem cells are also explained.

Pluripotent Stem Cells Book

Pluripotent Stem Cells


  • Author : Deepa Bhartiya
  • Publisher : BoD – Books on Demand
  • Release Date : 2013-08-28
  • Genre: Science
  • Pages : 642
  • ISBN 10 : 9789535111924

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Pluripotent Stem Cells Excerpt :

Stem cells have generated a lot of excitement among the researchers, clinicians and the public alike. Various types of stem cells are being evaluated for their regenerative potential. Marginal benefit resulting by transplanting autologus stem cells (deemed to be absolutely safe) in various clinical conditions has been proposed to be a growth factor effect rather than true regeneration. In contrast, various pre-clinical studies have been undertaken, using differentiated cells from embryonic stem cells or induced pluripotent stem cells have shown promise, functional improvement and no signs of teratoma formation. The scientists are not in a rush to reach the clinic but a handful of clinical studies have shown promise. This book is a collection of studies/reviews, beginning with an introduction to the pluripotent stem cells and covering various aspects like derivation, differentiation, ethics, etc., and hence would provide insight into the recent standing on the pluripotent stem cells biology. The chapters have been categorized into three sections, covering subjects ranging from the generation of pluripotent stem cells and various means of their derivation from embryonic as well as adult tissues, the mechanistic understanding of pluripotency and narrating the potential therapeutic implications of these in vitro generated cells in various diseases, in addition to the associated pros and cons in the same.

Medical Applications of iPS Cells Book

Medical Applications of iPS Cells


  • Author : Haruhisa Inoue
  • Publisher : Springer
  • Release Date : 2019-04-01
  • Genre: Medical
  • Pages : 190
  • ISBN 10 : 9789811336720

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Medical Applications of iPS Cells Excerpt :

This volume highlights recent advances using iPS cells in disease modeling and medical applications along with new technologies that enhance the power of iPS cells. While the discovery of iPS cells has provided excellent opportunities for developing models of human diseases, platforms for drug discovery and cell therapies, iPS cell technology still faces many challenges. Presenting the latest advances in this rapidly evolving research area, this book is intended to widen the community of researchers and clinicians interested in the exciting field of iPS cells.