Landmark Experiments in Molecular Biology Book

Landmark Experiments in Molecular Biology


  • Author : Michael Fry
  • Publisher : Academic Press
  • Release Date : 2016-06-10
  • Genre: Science
  • Pages : 570
  • ISBN 10 : 9780128021088

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Landmark Experiments in Molecular Biology Excerpt :

Landmark Experiments in Molecular Biology critically considers breakthrough experiments that have constituted major turning points in the birth and evolution of molecular biology. These experiments laid the foundations to molecular biology by uncovering the major players in the machinery of inheritance and biological information handling such as DNA, RNA, ribosomes, and proteins. Landmark Experiments in Molecular Biology combines an historical survey of the development of ideas, theories, and profiles of leading scientists with detailed scientific and technical analysis. Includes detailed analysis of classically designed and executed experiments Incorporates technical and scientific analysis along with historical background for a robust understanding of molecular biology discoveries Provides critical analysis of the history of molecular biology to inform the future of scientific discovery Examines the machinery of inheritance and biological information handling

Landmark Papers in Cell Biology Book

Landmark Papers in Cell Biology


  • Author : Joseph G. Gall
  • Publisher : CSHL Press
  • Release Date : 2001
  • Genre: Science
  • Pages : 778
  • ISBN 10 : 0879696028

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Landmark Papers in Cell Biology Excerpt :

Annotation Contains 42 seminal papers illustrating advances in cell biology, along with brief commentaries that place the papers in historical and intellectual context. All papers are studies of eukaryotes, and are grouped according to themes of genome organization and replication, transcription, nuclear envelope and nuclear import, mitosis and cell cycle control, cell membrane and extracellular matrix, protein synthesis and membrane traffic, and cytoskeleton. Lacks a subject index. Gall teaches embryology at the Carnegie Institution. McIntosh teaches cell biology at the University of Colorado. Annotation c. Book News, Inc., Portland, OR (booknews.com).

Molecular Cell Biology Book

Molecular Cell Biology


  • Author : Harvey F. Lodish
  • Publisher : W.H. Freeman
  • Release Date : 2012
  • Genre: Biología molecular
  • Pages : 973
  • ISBN 10 : 1464109818

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Molecular Cell Biology Excerpt :

With its acclaimed authors, cutting-edge content, emphasis on medical relevance and landmark experiments, Molecular Cell Biology is an impeccable textbook. Updated throughout, the seventh edition features new co-author Angelika Amon, a completely rewritten chapter on the Cell Cycle and significant updates to experimental techniques.

The Double Helix Book
Score: 3.5
From 18 Ratings

The Double Helix


  • Author : James D. Watson
  • Publisher : Simon and Schuster
  • Release Date : 2011-08-16
  • Genre: Science
  • Pages : 256
  • ISBN 10 : 9780743219174

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The Double Helix Excerpt :

The classic personal account of Watson and Crick’s groundbreaking discovery of the structure of DNA, now with an introduction by Sylvia Nasar, author of A Beautiful Mind. By identifying the structure of DNA, the molecule of life, Francis Crick and James Watson revolutionized biochemistry and won themselves a Nobel Prize. At the time, Watson was only twenty-four, a young scientist hungry to make his mark. His uncompromisingly honest account of the heady days of their thrilling sprint against other world-class researchers to solve one of science’s greatest mysteries gives a dazzlingly clear picture of a world of brilliant scientists with great gifts, very human ambitions, and bitter rivalries. With humility unspoiled by false modesty, Watson relates his and Crick’s desperate efforts to beat Linus Pauling to the Holy Grail of life sciences, the identification of the basic building block of life. Never has a scientist been so truthful in capturing in words the flavor of his work.

Advanced Methods in Molecular Biology and Biotechnology Book

Advanced Methods in Molecular Biology and Biotechnology


  • Author : Khalid Z. Masoodi
  • Publisher : Academic Press
  • Release Date : 2020-11-10
  • Genre: Science
  • Pages : 218
  • ISBN 10 : 9780128244500

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Advanced Methods in Molecular Biology and Biotechnology Excerpt :

Advanced Methods in Molecular Biology and Biotechnology: A Practical Lab Manual is a concise reference on common protocols and techniques for advanced molecular biology and biotechnology experimentation. Each chapter focuses on a different method, providing an overview before delving deeper into the procedure in a step-by-step approach. Techniques covered include genomic DNA extraction using cetyl trimethylammonium bromide (CTAB) and chloroform extraction, chromatographic techniques, ELISA, hybridization, gel electrophoresis, dot blot analysis and methods for studying polymerase chain reactions. Laboratory protocols and standard operating procedures for key equipment are also discussed, providing an instructive overview for lab work. This practical guide focuses on the latest advances and innovations in methods for molecular biology and biotechnology investigation, helping researchers and practitioners enhance and advance their own methodologies and take their work to the next level. Explores a wide range of advanced methods that can be applied by researchers in molecular biology and biotechnology Features clear, step-by-step instruction for applying the techniques covered Offers an introduction to laboratory protocols and recommendations for best practice when conducting experimental work, including standard operating procedures for key equipment

Molecular Biology of the Cell Book
Score: 4.5
From 5 Ratings

Molecular Biology of the Cell


  • Author : Bruce Alberts
  • Publisher : Unknown
  • Release Date : 2004
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 0815332181

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Molecular Biology of the Cell Excerpt :

Molecular Biology of RNA Book

Molecular Biology of RNA


  • Author : David Elliott
  • Publisher : Oxford University Press
  • Release Date : 2017-01-31
  • Genre: Science
  • Pages : 445
  • ISBN 10 : 9780191071034

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Molecular Biology of RNA Excerpt :

RNA plays a central, and until recently, somewhat underestimated role in the genetics underlying all forms of life on earth. This versatile molecule not only plays a crucial part in the synthesis of proteins from a DNA template, but is also intrinsically involved in the regulation of gene expression, and can even act as a catalyst in the form of a ribozyme. This latter property has led to the hypothesis that RNA - rather than DNA - could have played an essential part in the origin of life itself. This landmark text provides a systematic overview of the exciting and rapidly moving field of RNA biology. Key pioneering experiments, which provided the underlying evidence for what we now know, are described throughout, while the relevance of the subject to human disease is highlighted via frequent boxes. For the second edition of Molecular Biology of RNA, more introductory material has been incorporated at the beginning of the text, to aid students studying the subject for the first time. Throughout the text, new material has been included - particularly in relation to RNA binding domains, non-coding RNAs, and the connection between RNA biology and epigenetics. Finally, a new closing chapter discusses how exciting new technologies are being used to explore current topical areas of research.

Fundamental Molecular Biology Book

Fundamental Molecular Biology


  • Author : Lizabeth A. Allison
  • Publisher : Wiley
  • Release Date : 2011-10-18
  • Genre: Science
  • Pages : 672
  • ISBN 10 : 1118312597

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Fundamental Molecular Biology Excerpt :

This text is an unbound, binder-ready edition. Perfect for a single term on Molecular Biology and more accessible to beginning students in the field than its encyclopedic counterparts, Fundamental Molecular Biology provides a distillation of the essential concepts of molecular biology, and is supported by current examples, experimental evidence, an outstanding art program, multimedia support and a solid pedagogical framework. The text has been praised both for its balanced and solid coverage of traditional topics, and for its broad coverage of RNA structure and function, epigenetics and medical molecular biology.

Meselson  Stahl  and the Replication of DNA Book

Meselson Stahl and the Replication of DNA


  • Author : Frederic Lawrence Holmes
  • Publisher : Yale University Press
  • Release Date : 2008-10-01
  • Genre: Science
  • Pages : 528
  • ISBN 10 : 9780300129663

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Meselson Stahl and the Replication of DNA Excerpt :

In 1957 two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a “most beautiful” experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple, Frederic L. Holmes shows in this masterful account of Meselson and Stahl’s quest. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research--its unpredictability, excitement, intellectual challenge, and serendipitous windfalls, as well as its frustrations, unexpected diversions away from original plans, and chronic uncertainty. Holmes uses research logs, experimental films, correspondence, and interviews with the participants to record the history of Meselson and Stahl’s research, from their first thinking about the problem through the publication of their dramatic results. Holmes also reviews the scientific community’s reception of the experiment, the experiment’s influence on later investigations, and the reasons for its reputation as an exceptionally beautiful experiment.

The Black Box of Biology Book

The Black Box of Biology


  • Author : Michel Morange
  • Publisher : Harvard University Press
  • Release Date : 2020-06-09
  • Genre: Science
  • Pages : 529
  • ISBN 10 : 9780674281363

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The Black Box of Biology Excerpt :

In this masterful account, a historian of science surveys the molecular biology revolution, its origin and continuing impact. Since the 1930s, a molecular vision has been transforming biology. Michel Morange provides an incisive and overarching history of this transformation, from the early attempts to explain organisms by the structure of their chemical components, to the birth and consolidation of genetics, to the latest technologies and discoveries enabled by the new science of life. Morange revisits A History of Molecular Biology and offers new insights from the past twenty years into his analysis. The Black Box of Biology shows that what led to the incredible transformation of biology was not a simple accumulation of new results, but the molecularization of a large part of biology. In fact, Morange argues, the greatest biological achievements of the past few decades should still be understood within the molecular paradigm. What has happened is not the displacement of molecular biology by other techniques and avenues of research, but rather the fusion of molecular principles and concepts with those of other disciplines, including genetics, physics, structural chemistry, and computational biology. This has produced decisive changes, including the discoveries of regulatory RNAs, the development of massive scientific programs such as human genome sequencing, and the emergence of synthetic biology, systems biology, and epigenetics. Original, persuasive, and breathtaking in its scope, The Black Box of Biology sets a new standard for the history of the ongoing molecular revolution.

The Transforming Principle Book

The Transforming Principle


  • Author : Maclyn McCarty
  • Publisher : W. W. Norton & Company
  • Release Date : 1986
  • Genre: Philosophy
  • Pages : 258
  • ISBN 10 : 0393304507

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The Transforming Principle Excerpt :

Tells how research aimed at a cure for pneumonia, based on the determination of how an inactive bacterium became active, led to an understanding of the role of DNA

Molecular Cell Biology Book

Molecular Cell Biology


  • Author : Harvey Lodish
  • Publisher : W H Freeman & Company
  • Release Date : 1995
  • Genre: Science
  • Pages : 134455
  • ISBN 10 : 0716726742

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Molecular Cell Biology Excerpt :

With its acclaimed author team, cutting-edge content, emphasis on medical relevance, and coverage based on landmark experiments, "Molecular Cell Biology" has justly earned an impeccable reputation as an authoritative and exciting text. The new Sixth Edition features two new coauthors, expanded coverage of immunology and development, and new media tools for students and instructors.

Genetics and Molecular Biology Book

Genetics and Molecular Biology


  • Author : Robert F. Schleif
  • Publisher : Unknown
  • Release Date : 1993
  • Genre: Science
  • Pages : 726
  • ISBN 10 : UOM:39015039112068

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Genetics and Molecular Biology Excerpt :

In the first edition of Genetics and Molecular Biology, renowned researcher and award-winning teacher Robert Schleif produced a unique and stimulating text that was a notable departure from the standard compendia of facts and observations. Schleif's strategy was to present the underlying fundamental concepts of molecular biology with clear explanations and critical analysis of well-chosen experiments. The result was a concise and practical approach that offered students a real understanding of the subject. This second edition retains that valuable approach--with material thoroughly updated to include an integrated treatment of prokaryotic and eukaryotic molecular biology. Genetics and Molecular Biology is copiously illustrated with two-color line art. Each chapter includes an extensive list of important references to the primary literature, as well as many innovative and thought-provoking problems on material covered in the text or on related topics. These help focus the student's attention of a variety of critical issues. Solutions are provided for half of the problems. Praise for the first edition: "Schleif's Genetics and Molecular Biology... is a remarkable achievement. It is an advanced text, derived from material taught largely to postgraduates, and will probably be thought best suited to budding professionals in molecular genetics. In some ways this would be a pity, because there is also gold here for the rest of us... The lessons here in dealing with the information explosion in biology are that an ounce of rationale is worth a pound of facts and that, for educational value, there is nothing to beat an author writing about stuff he knows from theinside."--Nature. "Schleif presents a quantitative, chemically rigorous approach to analyzing problems in molecular biology. The text is unique and clearly superior to any currently available."--R.L. Bernstein, San Francisco State University. "The greatest strength is the author's ability to challenge the student to b

Molecular Machines Book

Molecular Machines


  • Author : Giovanni Zocchi
  • Publisher : Princeton University Press
  • Release Date : 2018-07-10
  • Genre: Science
  • Pages : 188
  • ISBN 10 : 9780691173863

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Molecular Machines Excerpt :

Molecular Machines presents a dynamic new approach to the physics of enzymes and DNA from the perspective of materials science. Unified around the concept of molecular deformability—how proteins and DNA stretch, fold, and change shape—this book describes the complex molecules of life from the innovative perspective of materials properties and dynamics, in contrast to structural or purely chemical approaches. It covers a wealth of topics, including nonlinear deformability of enzymes and DNA; the chemo-dynamic cycle of enzymes; supra-molecular constructions with internal stress; nano-rheology and viscoelasticity; and chemical kinetics, Brownian motion, and barrier crossing. Essential reading for researchers in materials science, engineering, and nanotechnology, the book also describes the landmark experiments that have established the materials properties and energy landscape of large biological molecules. Molecular Machines is also ideal for the classroom. It gives graduate students a working knowledge of model building in statistical mechanics, making it an essential resource for tomorrow's experimentalists in this cutting-edge field. In addition, mathematical methods are introduced in the bio-molecular context—for example, DNA conformational transitions are used to illustrate the transfer matrix formalism. The result is a generalized approach to mathematical problem solving that enables students to apply their findings more broadly. Molecular Machines represents the next leap forward in nanoscience, as researchers strive to harness proteins, enzymes, and DNA as veritable machines in medicine, technology, and beyond.

Recombinant DNA Book

Recombinant DNA


  • Author : James D. Watson
  • Publisher : Unknown
  • Release Date : 2007-01-01
  • Genre: Genetic recombination
  • Pages : 474
  • ISBN 10 : 1429203129

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Recombinant DNA Excerpt :

This text presents an introduction to the concepts and techniques of recombinant DNA research and their dramatic results. It explores core concepts in molecular biology in a contemporary inquiry-based context, building its coverage around the landmark experiments that redefined our understanding of DNA.