Micro  and Nanotechnology in Vaccine Development Book

Micro and Nanotechnology in Vaccine Development


  • Author : Mariusz Skwarczynski
  • Publisher : William Andrew
  • Release Date : 2016-09-20
  • Genre: Medical
  • Pages : 460
  • ISBN 10 : 9780323400299

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Micro and Nanotechnology in Vaccine Development Excerpt :

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Micro  and Nanotechnology in Vaccine Development Book

Micro and Nanotechnology in Vaccine Development


  • Author : Mariusz Skwarczynski
  • Publisher : William Andrew
  • Release Date : 2016-09-08
  • Genre: Uncategoriezed
  • Pages : 456
  • ISBN 10 : 0323399819

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Micro and Nanotechnology in Vaccine Development Excerpt :

This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine developmentAllows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their developmentIncludes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines

Silk based Drug Delivery Systems Book

Silk based Drug Delivery Systems


  • Author : Elia Bari
  • Publisher : Royal Society of Chemistry
  • Release Date : 2020-10-07
  • Genre: Science
  • Pages : 243
  • ISBN 10 : 9781788017725

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Silk based Drug Delivery Systems Excerpt :

Covering spider silk and silk worm cocoons, the editors elucidate the extraction, structure and properties of silk sericin and silk fibroin.

Nanotherapeutics in Cancer Vaccination and Challenges Book

Nanotherapeutics in Cancer Vaccination and Challenges


  • Author : Mahfoozur Rahman
  • Publisher : Academic Press
  • Release Date : 2022-03-03
  • Genre: Business & Economics
  • Pages : 494
  • ISBN 10 : 9780128236871

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Nanotherapeutics in Cancer Vaccination and Challenges Excerpt :

Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy. Presents the progress made in cancer medicines from conventional to targeted therapy Covers the present state-of-the-art of cancer nanomedicines and upcoming therapeutic cancer vaccination Contains a focus on advanced nanomaterials that are utilized for encapsulation of nucleic acid, mRNA, DNA, siRNA

Nanoparticles for Rational Vaccine Design Book

Nanoparticles for Rational Vaccine Design


  • Author : Harvinder Singh Gill
  • Publisher : Springer Nature
  • Release Date : 2021-08-30
  • Genre: Medical
  • Pages : 130
  • ISBN 10 : 9783030850678

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Nanoparticles for Rational Vaccine Design Excerpt :

This book introduces nanoparticles as a powerful platform for vaccine design. Current challenges in vaccine development are discussed and the unique advantages nanoparticles provide in overcoming these challenges are explored. The authors offer fascinating insights into the immunological assets of using nanoparticles as delivery vehicles or adjuvants and present different materials that are being used in nanoparticle-based vaccine development, covering peptides, proteins, polymers, virus-like particles, and liposomes. Its contemporary research insights and practical examples for applications make this volume an inspiring read for researchers and clinicians in vaccinology and immunology. Chapter "Liposome Formulations as Adjuvants for Vaccines" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance Book

Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance


  • Author : Muthupandian Saravanan
  • Publisher : Elsevier
  • Release Date : 2022-06-24
  • Genre: Technology & Engineering
  • Pages : 788
  • ISBN 10 : 9780323998109

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Emerging Nanomaterials and Nano based Drug Delivery Approaches to Combat Antimicrobial Resistance Excerpt :

Emerging Nanomaterials and Nano-based Drug Delivery Approaches to Combat Antimicrobial Resistance focuses on recent and emerging trends surrounding nanomaterials and nano-drug delivery approaches to combat antimicrobial resistance. The relationship between nanomaterials and antimicrobial activity needs to be deeply explored to meet the challenges of combating antimicrobial resistance. The content of this book is divided into three main topic areas, including (i) how to overcome the existing traditional approaches to combat antimicrobial resistance, (ii) applying multiple drug delivery mechanisms to target multi-drug resistant microbes, and (iii) how nanomaterials can be used as drug carriers. This is an important reference source for those looking to understand how nanotechnology plays an important role in combatting disease and infection. As antimicrobial resistance threatens the effective prevention and treatment of an ever-increasing range of infections caused by bacteria, parasites, viruses, and fungi, this is a timely resource. Outlines how to overcome existing traditional approaches to combatting antimicrobial resistance Explains how to apply multiple drug delivery mechanisms (MDR) to the target area in order to better combat antimicrobial resistance Shows how nanomaterials are used as drug carriers in this context

Drug Delivery Technology Development in Canada Book

Drug Delivery Technology Development in Canada


  • Author : Kishor M.Wasan
  • Publisher : MDPI
  • Release Date : 2019-12-19
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9783039280049

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Drug Delivery Technology Development in Canada Excerpt :

Canada continues to have a rich history of ground-breaking research in drug delivery within academic institutions, pharmaceutical industry and the biotechnology community. Over the past 30 years, numerous Canadian-based biotechnology companies have been formed from the inventions conceived and developed within academic institutions that have led to the development of important drug delivery products that have enhanced the landscape of drug therapy in the treatment of cancer to infectious diseases. This Special Issue serves to highlight and capture the contemporary progress of drug delivery within the prevailing Canadian context. We invite articles on all aspects of drug delivery sciences from pre-clinical formulation development to human clinical trials that bring to light the world-class research currently undertaken in Canada for this Special Issue.

Synthetic Peptide Vaccine Models Book

Synthetic Peptide Vaccine Models


  • Author : Mesut Karahan
  • Publisher : CRC Press
  • Release Date : 2021-03-01
  • Genre: Science
  • Pages : 292
  • ISBN 10 : 9781000342772

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Synthetic Peptide Vaccine Models Excerpt :

A new generation of technological vaccines protect against many infectious diseases. This book describes synthetic peptide-based vaccine prototypes – the future of vaccination. Production of peptides becomes simple using automatic synthesizers. Peptides are weak immunogen and need adjuvants to provide an effective autoimmune response, which is why peptide antigens are conjugated with biopolymers and loaded with nanoparticles. The book illustrates the use of peptides vaccine systems and makes predictions of future development not only for infectious diseases, but also for cancers and brain diseases such as Alzheimer, Parkinson and psychiatric diseases. Key Features Summarizes current studies on technological vaccines Describes the uses of vaccines for the prevention of brain diseases Reviews the ways different polymers are used to enhance vaccine efficacy

Nanomaterials for Clinical Applications Book

Nanomaterials for Clinical Applications


  • Author : Costas Demetzos
  • Publisher : Elsevier
  • Release Date : 2020-02-14
  • Genre: Technology & Engineering
  • Pages : 322
  • ISBN 10 : 9780128168769

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Nanomaterials for Clinical Applications Excerpt :

Nanomaterials in Clinical Medicine: Case Studies in Nanomedicines focuses on the nanomaterials that can be formulated as drug delivery vehicles, such as liposomes, micelles, nanoemulsions and nanogels. Their physicochemical, morphological, thermo-dynamical and nanotoxicological properties are analyzed with respect to the design and development of drug delivery nanosystems for the encapsulation of an active pharmaceutical ingredient and its controlled release. Each chapter covers basic properties, the nanosystem (e.g., liposomes), the added value in drug delivery and targeting, and future perspectives. Case studies and examples of how nanomaterials are being used in clinical medicine, including marketed liposomal medicines and medical utility and regimens are also included. Particular attention is given to new nanocarriers, such as elastic liposomes, lipid polymeric hybrid nanoparticles, organogel, nanofibers carbon nanomaterials, quantum dots and inorganic nanoparticles. This book is an important information source for those wanting to increase their understanding of what major nanomaterials are being used to create more effective drug delivery systems. Summarizes the major nanomaterials used in clinical medicine, explaining how their properties make them suitable for this purpose Explains how nanomaterials are used to create increasingly efficient drug delivery vehicles Includes real-life examples, demonstrating how nanomaterials are being used in medical practice

Applications of Nanobiotechnology for Neglected Tropical Diseases Book

Applications of Nanobiotechnology for Neglected Tropical Diseases


  • Author : Fabio Rocha Formiga
  • Publisher : Academic Press
  • Release Date : 2021-02-20
  • Genre: Medical
  • Pages : 604
  • ISBN 10 : 9780128211014

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Applications of Nanobiotechnology for Neglected Tropical Diseases Excerpt :

Applications of Nanobiotechnology for Neglected Tropical Diseases describes recent advances in nanobiotechnology that can be applied to reducing the global disease burden of neglected tropical diseases (NTDs). The book explores the application of nanotechnology on the development of safe, effective, and reliable tools to prevent, diagnose, and treat NTDs. Furthermore, Applications of Nanobiotechnology for Neglected Tropical Diseases includes multidisciplinary content, combining knowledge from biochemistry, medicinal chemistry, material sciences, pharmacology, and pharmaceutics. The book is divided into three main parts, each outlining one major type of approach: (1) nano-based approaches for prevention, (2) nano-diagnostics and detection, and (3) nanotherapeutics. Each part contains chapters that delve into the different applications of the type of approach being presented in that part. A discussion of other approaches against NTD follows these three parts. This book is remarkable in its ability to encompass and thoroughly explain the latest techniques in nanobiotechnology, from basic research to patient-oriented investigation. Offers a broad overview of nanobiotechnology applied to the prevention, diagnostics, and treatment of NTDs Presents cutting-edge recent advances in nanobiotechnology, focusing on diseases reported by the World Health Organization’s NTDs Roadmap (e.g., leishmaniasis, malaria, schistosomiasis, filariasis, etc.) Provides a deep discussion about ground-breaking approaches designed to meet the medical needs of patients suffering from NTDs Gives examples of multidisciplinary investigations into NTDs, from research labs to clinics

Nanoparticles in Medicine Book

Nanoparticles in Medicine


  • Author : Ashutosh Kumar Shukla
  • Publisher : Springer Nature
  • Release Date : 2019-08-31
  • Genre: Medical
  • Pages : 220
  • ISBN 10 : 9789811389542

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Nanoparticles in Medicine Excerpt :

This book describes the medical applications of inorganic nanoparticles. Nanomedicine is a relatively advanced field, which enhances the treatment of various diseases, offering new options for overcoming the problems associated with the use of conventional medicines. Discussing the toxicological and safety aspects associated with medical applications of nanoparticles, the book presents the latest research on topics such as emerging nanomaterials for cancer therapy, applications of nanoparticles in dentistry, and fluoride nanoparticles for biomedical applications, and also includes chapters on the use of nanoparticles such as silver and gold. /div

Omics Approaches and Technologies in COVID 19 Book

Omics Approaches and Technologies in COVID 19


  • Author : Debmalya Barh
  • Publisher : Academic Press
  • Release Date : 2022-12-01
  • Genre: Business & Economics
  • Pages : 464
  • ISBN 10 : 9780323986212

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Omics Approaches and Technologies in COVID 19 Excerpt :

Omics Approaches and Technologies in COVID-19 discusses current and in development technologies used to fight the SARS-CoV-2 pandemic. Based on the research developed since the virus' outbreak, experts from around the world present perspectives on how recent technologies can help diagnose, treat and control. The book discusses topics such as genomics, meta-genomics, nutrigenomics, transcriptomics, proteomics, metabolomics, epigenomics, multi-omics and pan-genomics approaches, CRISPR, host-pathogen interactions, systems biology, artificial intelligence and machine learning applied to COVID-19, bioinformatics, mathematical modeling, and big data. In addition, it presents smart technologies to control SARS-CoV-2 transmission and technologies for the prediction of patients’ health conditions and treatment outcomes. This is a valuable resource for graduate students, researchers and members of the biomedical field who are interested in learning more about novel approaches and technologies used to tackle the COVID-19 pandemic. Presents an overview of various omics-based strategies used in identifying the origin of SARS-CoV-2 Discusses omics approaches used in developing novel rapid diagnostics for COVID-19 Brings information on how omics technologies have minimized the time taken to develop potential drugs and vaccines Explains how applications of digital and smart technologies can be used to control the pandemic

Industrial Applications of Nanomaterials Book

Industrial Applications of Nanomaterials


  • Author : Sabu Thomas
  • Publisher : Elsevier
  • Release Date : 2019-08-12
  • Genre: Technology & Engineering
  • Pages : 534
  • ISBN 10 : 9780128157503

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Industrial Applications of Nanomaterials Excerpt :

Industrial Applications of Nanomaterials explains the industry based applications of nanomaterials, along with their environmental impacts, lifecycle analysis, safety and sustainability. This book brings together the industrial applications of nanomaterials with the incorporation of various technologies and areas, covering new trends and challenges. Significant properties, safety and sustainability and environmental impacts of synthesis routes are also explored, as are major industrial applications, including agriculture, medicine, communication, construction, energy, and in the military. This book is an important information source for those in research and development who want to gain a greater understanding of how nanotechnology is being used to create cheaper, more efficient products. Explains how different classes of nanomaterials are being used to create cheaper, more efficient products Explores the environmental impacts of using a variety of nanomaterials Discusses the challenges faced by engineers looking to integrate nanotechnology in new product development

Surfactants and Detergents Book

Surfactants and Detergents


  • Author : Ashim Dutta
  • Publisher : BoD – Books on Demand
  • Release Date : 2019-11-20
  • Genre: Science
  • Pages : 103
  • ISBN 10 : 9781789846607

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Surfactants and Detergents Excerpt :

Surfactants by virtue of their structure form self-assembled organized structures that exhibit fascinating properties useful for a wide range of applications. This book is a compilation of chapters from leading experts highlighting the use of specific surfactants and their functional properties in new and emerging areas of science and technology. The first two chapters of this book discuss the various applications of surfactants, including their use in cosmetics, oil recovery from rocks and mineral processing. Subsequent chapters cover advanced topics like new-generation polymer-based nanoparticles with microbial activity and complex phase systems formed as a result of charge-induced interactions between surfactants, polymers and proteins with potential applications in medical devices. In addition, this book reports for the first time on bio-surfactants extracted from micro-organisms present in the clouds. This report is not the only one of its kind, but it opens up a totally new area of research in terms of an unexplored source of bio-surfactants. It also paves the way for understanding their role in controlling our atmosphere and climate.