Micro Drops and Digital Microfluidics Book

Micro Drops and Digital Microfluidics


  • Author : Jean Berthier
  • Publisher : William Andrew
  • Release Date : 2012-12-31
  • Genre: Science
  • Pages : 560
  • ISBN 10 : 9781455728008

GET BOOK
Micro Drops and Digital Microfluidics Book Description :

In this 2nd edition of Micro-Drops and Digital Microfluidics, Jean Berthier explores the fundamentals and applications of digital microfluidics, enabling engineers and scientists to design this important enabling technology into devices and harness the considerable potential of digital microfluidics in testing and data collection. This book describes the most recent developments in digital microfluidics, with a specific focus on the computational, theoretical and experimental study of microdrops. Unique in its emphasis on digital microfluidics and with diverse applications ranging from drug delivery to point-of-care diagnostic chips, organic synthesis to microreactors, Micro-Drops and Digital Microfluidics meets the needs of audiences across the fields of bioengineering and biotechnology, and electrical and chemical engineering. Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops." A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow) A fresh perspective on the future of microfluidics

Micro Drops and Digital Microfluidics Book

Micro Drops and Digital Microfluidics


  • Author : Jean Berthier
  • Publisher : Elsevier
  • Release Date : 2008-03-20
  • Genre: Technology & Engineering
  • Pages : 350
  • ISBN 10 : 9780815518358

GET BOOK
Micro Drops and Digital Microfluidics Book Description :

After spending over 12 years developing new microsystems for biotechnology – especially concerned with the microfluidic aspects of these devices – Jean Berthier is considered a leading authority in the field. Now, following the success of his book, Microfluidics for Biotechnology, Dr. Berthier returns to explain how new miniaturization techniques have dramatically expanded the area of microfluidic applications and microsystems into microdrops and digital microfluidics. Engineers interested in designing more versatile microsystems and students who seek to learn the fundamentals of microfluidics will all appreciate the wide-range of information found within Microdrops and Digital Microfluidics. The most recent developments in digital microfluidics are described in clear detail, with a specific focus on the computational, theoretical and experimental study of microdrops. • Over 500 equations and more than 400 illustrations. • Authoritative reporting on the latest changes in microfluidic science, where microscopic liquid volumes are handled as ""microdrops"" and separately from ""nanodrops."" • A methodical examination of how liquid microdrops behave in the complex geometries of modern miniaturized systems and interact with different morphological (micro-fabricated, textured) solid substrates. • A thorough explanation of how capillary forces act on liquid interfaces in contact with micro-fabricated surfaces. • Analysis of how droplets can be manipulated, handled, or transported using electric fields (electrowetting), acoustic actuation (surface acoustic waves), or by a carrier liquid (microflow). • A fresh perspective on the future of microfluidics.

Microfluidics for Biotechnology Book

Microfluidics for Biotechnology


  • Author : Jean Berthier
  • Publisher : Artech House
  • Release Date : 2010
  • Genre: Science
  • Pages : 483
  • ISBN 10 : 9781596934443

GET BOOK
Microfluidics for Biotechnology Book Description :

The application of microfluidics to biotechnology is an exciting new area that has already begun to revolutionize how researchers study and manipulate macromolecules like DNA, proteins and cells in vitro and within living organisms. Now in a newly revised and expanded second edition, the Artech House bestseller, Microfluidics for Biotechnology brings you to the cutting edge of this burgeoning field. Among the numerous updates, the second edition features three entirely new chapters on: non-dimensional numbers in microfluidics; interface, capillarity and microdrops; and digital, two-phase and droplet microfluidics.Presenting an enlightening balance of numerical approaches, theory, and experimental examples, this book provides a detailed look at the mechanical behavior of the different types of micro/nano particles and macromolecules that are used in biotechnology. You gain a solid understanding of microfluidics theory and the mechanics of microflows and microdrops. The book examines the diffusion of species and nanoparticles, including continuous flow and discrete Monte-Carlo methods.This unique volume describes the transport and dispersion of biochemical species and particles. You learn how to model biochemical reactions, including DNA hybridization and enzymatic reactions. Moreover, the book helps you master the theory, applications, and modeling of magnetic beads behavior and provides an overview of self-assembly and magnetic composite. Other key topics include the electric manipulation of micro/nanoparticles and macromolecules and the experimental aspects of biological macromolecule manipulation.

The Physics of Microdroplets Book

The Physics of Microdroplets


  • Author : Jean Berthier
  • Publisher : John Wiley & Sons
  • Release Date : 2012-04-30
  • Genre: Technology & Engineering
  • Pages : 392
  • ISBN 10 : 9781118401330

GET BOOK
The Physics of Microdroplets Book Description :

The Physics of Microdroplets gives the reader the theoretical and numerical tools to understand, explain, calculate, and predict the often nonintuitive observed behavior of droplets in microsystems. Microdrops and interfaces are now a common feature in most fluidic microsystems, from biology, to biotechnology, materials science, 3D-microelectronics, optofluidics, and mechatronics. On the other hand, the behavior of droplets and interfaces in today's microsystems is complicated and involves complex 3D geometrical considerations. From a numerical standpoint, the treatment of interfaces separating different immiscible phases is difficult. After a chapter dedicated to the general theory of wetting, this practical book successively details: The theory of 3D liquid interfaces The formulas for volume and surface of sessile and pancake droplets The behavior of sessile droplets The behavior of droplets between tapered plates and in wedges The behavior of droplets in microchannels The effect of capillarity with the analysis of capillary rise The onset of spontaneous capillary flow in open microfluidic systems The interaction between droplets, like engulfment The theory and application of electrowetting The state of the art for the approach of 3D-microelectronics using capillary alignment

Digital Microfluidic Biochips Book

Digital Microfluidic Biochips


  • Author : Krishnendu Chakrabarty
  • Publisher : CRC Press
  • Release Date : 2018-10-03
  • Genre: Technology & Engineering
  • Pages : 228
  • ISBN 10 : 9781420008302

GET BOOK
Digital Microfluidic Biochips Book Description :

Digital Microfluidic Biochips focuses on the automated design and production of microfluidic-based biochips for large-scale bioassays and safety-critical applications. Bridging areas of electronic design automation with microfluidic biochip research, the authors present a system-level design automation framework that addresses key issues in the design, analysis, and testing of digital microfluidic biochips. The book describes a new generation of microfluidic biochips with more complex designs that offer dynamic reconfigurability, system scalability, system integration, and defect tolerance. Part I describes a unified design methodology that targets design optimization under resource constraints. Part II investigates cost-effective testing techniques for digital microfluidic biochips that include test resource optimization and fault detection while running normal bioassays. Part III focuses on different reconfiguration-based defect tolerance techniques designed to increase the yield and dependability of digital microfluidic biochips. Expanding upon results from ongoing research on CAD for biochips at Duke University, this book presents new design methodologies that address some of the limitations in current full-custom design techniques. Digital Microfluidic Biochips is an essential resource for achieving the integration of microfluidic components in the next generation of system-on-chip and system-in-package designs.

Open Microfluidics Book

Open Microfluidics


  • Author : Jean Berthier
  • Publisher : John Wiley & Sons
  • Release Date : 2016-07-20
  • Genre: Science
  • Pages : 336
  • ISBN 10 : 9781118720820

GET BOOK
Open Microfluidics Book Description :

Open microfluidics or open-surface is becoming fundamental in scientific domains such as biotechnology, biology and space. First, such systems and devices based on open microfluidics make use of capillary forces to move fluids, without any need for external energy. Second, the “openness” of the flow facilitates the accessibility to the liquid in biotechnology and biology, and reduces the weight in space applications. This book has been conceived to give the reader the fundamental basis of open microfluidics. It covers successively The theory of spontaneous capillary flow, with the general conditions for spontaneous capillary flow, and the dynamic aspects of such flows. The formation of capillary filaments which are associated to small contact angles and sharp grooves. The study of capillary flow in open rectangular, pseudo-rectangular and trapezoidal open microchannels. The dynamics of open capillary flows in grooves with a focus on capillary resistors. The case of very viscous liquids is analyzed. An analysis of suspended capillary flows: such flows move in suspended channels devoid of top cover and bottom plate. Their accessibility is reinforced, and such systems are becoming fundamental in biology. An analysis of “rails” microfluidics, which are flows that move in channels devoid of side walls. This geometry has the advantage to be compatible with capillary networks, which are now of great interest in biotechnology, for molecular detection for example. Paper-based microfluidics where liquids wick flat paper matrix. Applications concern bioassays such as point of care devices (POC). Thread-based microfluidics is a new domain of investigation. It is seeing presently many new developments in the domain of separation and filtration, and opens the way to smart bandages and tissue engineering. The book is intended to cover the theoretical aspects of open microfluidics, experimental approaches, and examples of application.

Micro Electrode Dot Array Digital Microfluidic Biochips Book

Micro Electrode Dot Array Digital Microfluidic Biochips


  • Author : Zipeng Li
  • Publisher : Springer
  • Release Date : 2018-12-14
  • Genre: Technology & Engineering
  • Pages : 144
  • ISBN 10 : 9783030029647

GET BOOK
Micro Electrode Dot Array Digital Microfluidic Biochips Book Description :

This book provides an insightful guide to the design, testing and optimization of micro-electrode-dot-array (MEDA) digital microfluidic biochips. The authors focus on the characteristics specific for MEDA biochips, e.g., real-time sensing and advanced microfluidic operations like lamination mixing and droplet shape morphing. Readers will be enabled to enhance the automated design and use of MEDA and to develop a set of solutions to facilitate the full exploitation of design complexities that are possible with standard CMOS fabrication techniques. The book provides the first set of design automation and test techniques for MEDA biochips. The methods described in this book have been validated using fabricated MEDA biochips in the laboratory. Readers will benefit from an in-depth look at the MEDA platform and how to combine microfluidics with software, e.g., applying biomolecular protocols to software-controlled and cyberphysical microfluidic biochips.

Open Channel Microfluidics Book

Open Channel Microfluidics


  • Author : Jean Berthier
  • Publisher : Morgan & Claypool Publishers
  • Release Date : 2019-09-04
  • Genre: Technology & Engineering
  • Pages : 170
  • ISBN 10 : 9781643276649

GET BOOK
Open Channel Microfluidics Book Description :

Open microfluidics, the study of microflows having a boundary with surrounding air, encompasses different aspects such as paper or thread-based microfluidics, droplet microfluidics and open-channel microfluidics. Open-channel microflow is a flow at the micro-scale, guided by solid structures, and having at least a free boundary (with air or vapor) other than the advancing meniscus. This book is devoted to the study of open-channel microfluidics which (contrary to paper or thread or droplet microfluidics) is still very sparsely documented, but bears many new applications in biology, biotechnology, medicine, material and space sciences. Capillarity being the principal force triggering an open microflow, the principles of capillarity are first recalled. The onset of open-channel microflow is next analyzed and the fundamental notion of generalized Cassie angle (the apparent contact angle which accounts for the presence of air) is presented. The theory of the dynamics of open-channel microflows is then developed, using the notion of averaged friction length which accounts for the presence of air along the boundaries of the flow domain. Different channel morphologies are studied and geometrical features such as valves and capillary pumps are examined. An introduction to two-phase open-channel microflows is also presented showing that immiscible plugs can be transported by an open-channel flow. Finally, a selection of interesting applications in the domains of space, materials, medicine and biology is presented, showing the potentialities of open-channel microfluidics.

Microfluidics for Pharmaceutical Applications Book

Microfluidics for Pharmaceutical Applications


  • Author : Helder A. Santos
  • Publisher : William Andrew
  • Release Date : 2018-10-12
  • Genre: Science
  • Pages : 495
  • ISBN 10 : 9780128126608

GET BOOK
Microfluidics for Pharmaceutical Applications Book Description :

Microfluidics for Pharmaceutical Applications: From Nano/Micro Systems Fabrication to Controlled Drug Delivery is a concept-orientated reference that features case studies on utilizing microfluidics for drug delivery applications. It is a valuable learning reference on microfluidics for drug delivery applications and assists practitioners developing novel drug delivery platforms using microfluidics. It explores advances in microfluidics for drug delivery applications from different perspectives, covering device fabrication, fluid dynamics, cutting-edge microfluidic technology in the global drug delivery industry, lab-on-chip nano/micro fabrication and drug encapsulation, cell encapsulation and delivery, and cell- drug interaction screening. These microfluidic platforms have revolutionized the drug delivery field, but also show great potential for industrial applications. Presents detailed coverage on the fabrication of novel drug delivery systems with desired characteristics, such as uniform size, Janus particles, and particular or combined responsiveness Includes a variety of case studies that explain principles Focuses on commercialization, cost, safety, society and educational issues of microfluidic applications, showing how microfluidics is used in the real world

Microdrop Generation Book

Microdrop Generation


  • Author : Eric R. Lee
  • Publisher : CRC Press
  • Release Date : 2018-10-03
  • Genre: Technology & Engineering
  • Pages : 272
  • ISBN 10 : 9781420039986

GET BOOK
Microdrop Generation Book Description :

The applications and use of inkjet-like microfluidic drop ejectors have grown rapidly in many fields, including biotechnology, drug discovery, combinatorial chemistry, and microfabrication. Yet to date, end users and even designers of microdrop systems for scientific applications have had no books to reference on the subject. Microdrop Generation meets the needs of all those who need to understand the physics and engineering behind microdrop technology. It also contains detailed, how-to information on the practical construction, operation, troubleshooting, and fluid formulation for microdrop ejection systems. Written by a highly experienced practitioner of the art, the book is organized as a self-contained tutorial of microdrop technology ideal for those new to the field.

Microfluidics Book

Microfluidics


  • Author : Yujun Song
  • Publisher : John Wiley & Sons
  • Release Date : 2018-01-04
  • Genre: Science
  • Pages : 544
  • ISBN 10 : 9783527800650

GET BOOK
Microfluidics Book Description :

The first book offering a global overview of fundamental microfluidics and the wide range of possible applications, for example, in chemistry, biology, and biomedical science. As such, it summarizes recent progress in microfluidics, including its origin and development, the theoretical fundamentals, and fabrication techniques for microfluidic devices. The book also comprehensively covers the fluid mechanics, physics and chemistry as well as applications in such different fields as detection and synthesis of inorganic and organic materials. A useful reference for non-specialists and a basic guideline for research scientists and technicians already active in this field or intending to work in microfluidics.

Design Automation Methods and Tools for Microfluidics Based Biochips Book

Design Automation Methods and Tools for Microfluidics Based Biochips


  • Author : Jun Zeng
  • Publisher : Springer Science & Business Media
  • Release Date : 2006-11-08
  • Genre: Technology & Engineering
  • Pages : 403
  • ISBN 10 : 9781402051234

GET BOOK
Design Automation Methods and Tools for Microfluidics Based Biochips Book Description :

Design Automation Methods and Tools for Microfluidics-Based Biochips deals with all aspects of design automation for microfluidics-based biochips. Experts have contributed chapters on many aspects of biochip design automation. Topics covered include: device modeling; adaptation of bioassays for on-chip implementations; numerical methods and simulation tools; architectural synthesis, scheduling and binding of assay operations; physical design and module placement; fault modeling and testing; and reconfiguration methods.

Microdroplet Technology Book
Score: 5
From 1 Ratings

Microdroplet Technology


  • Author : Philip Day
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-07-28
  • Genre: Science
  • Pages : 246
  • ISBN 10 : 9781461432654

GET BOOK
Microdroplet Technology Book Description :

Microdroplet technology has recently emerged to provide new and diverse applications via microfluidic functionality, especially in various areas of biology and chemistry. This book, then, gives an overview of the principle components and wide-ranging applications for state-of-the-art of droplet-based microfluidics. Chapter authors are internationally-leading researchers from chemistry, biology, physics and engineering that present various key aspects of micrdroplet technology -- fundamental flow physics, methodology and components for flow control, applications in biology and chemistry, and a discussion of future perspectives. This book acts as a reference for academics, post-graduate students, and researcher wishing to deepen their understand of microfluidics and introduce optimal design and operation of new droplet-based microfluidic devices for more comprehensive analyte assessments.

Advances in Microfluidics Book

Advances in Microfluidics


  • Author : Xiao-Ying Yu
  • Publisher : BoD – Books on Demand
  • Release Date : 2016-11-23
  • Genre: Science
  • Pages : 422
  • ISBN 10 : 9789535127857

GET BOOK
Advances in Microfluidics Book Description :

Increasing innovations and applications make microfluidics a versatile choice for researchers in many disciplines. This book consists of multiple review chapters that aim to cover recent advances and new applications of microfluidics in biology, electronics, energy, and materials sciences. It provides comprehensive views of various aspects of microfluidics ranging from fundamentals of fabrication, flow control, and droplet manipulation to the most recent exploration in emerging areas such as material synthesis, imaging and novel spectroscopy, and marriage with electronics. The chapters have many illustrations showcasing exciting results. This book should be useful for those who are eager to learn more about microfluidics as well as researchers who want to pick up new concepts and developments in this fast-growing field.

Nanofluidics and Microfluidics Book
Score: 5
From 1 Ratings

Nanofluidics and Microfluidics


  • Author : Shaurya Prakash
  • Publisher : William Andrew
  • Release Date : 2014-01-16
  • Genre: Technology & Engineering
  • Pages : 312
  • ISBN 10 : 9781437744705

GET BOOK
Nanofluidics and Microfluidics Book Description :

To provide an interdisciplinary readership with the necessary toolkit to work with micro- and nanofluidics, this book provides basic theory, fundamentals of microfabrication, advanced fabrication methods, device characterization methods and detailed examples of applications of nanofluidics devices and systems. Case studies describing fabrication of complex micro- and nanoscale systems help the reader gain a practical understanding of developing and fabricating such systems. The resulting work covers the fundamentals, processes and applied challenges of functional engineered nanofluidic systems for a variety of different applications, including discussions of lab-on-chip, bio-related applications and emerging technologies for energy and environmental engineering. The fundamentals of micro- and nanofluidic systems and micro- and nanofabrication techniques provide readers from a variety of academic backgrounds with the understanding required to develop new systems and applications. Case studies introduce and illustrate state-of-the-art applications across areas, including lab-on-chip, energy and bio-based applications. Prakash and Yeom provide readers with an essential toolkit to take micro- and nanofluidic applications out of the research lab and into commercial and laboratory applications.

Encyclopedia of Microfluidics and Nanofluidics Book

Encyclopedia of Microfluidics and Nanofluidics


  • Author : Dongqing Li
  • Publisher : Springer Science & Business Media
  • Release Date : 2008-08-06
  • Genre: Technology & Engineering
  • Pages : 2226
  • ISBN 10 : 9780387324685

GET BOOK
Encyclopedia of Microfluidics and Nanofluidics Book Description :

Covering all aspects of transport phenomena on the nano- and micro-scale, this encyclopedia features over 750 entries in three alphabetically-arranged volumes including the most up-to-date research, insights, and applied techniques across all areas. Coverage includes electrical double-layers, optofluidics, DNC lab-on-a-chip, nanosensors, and more.

Microfluidic Devices for Biomedical Applications Book

Microfluidic Devices for Biomedical Applications


  • Author : Xiujun James Li
  • Publisher : Elsevier
  • Release Date : 2013-10-31
  • Genre: Technology & Engineering
  • Pages : 676
  • ISBN 10 : 9780857097040

GET BOOK
Microfluidic Devices for Biomedical Applications Book Description :

Microfluidics or lab-on-a-chip (LOC) is an important technology suitable for numerous applications from drug delivery to tissue engineering. Microfluidic devices for biomedical applications discusses the fundamentals of microfluidics and explores in detail a wide range of medical applications. The first part of the book reviews the fundamentals of microfluidic technologies for biomedical applications with chapters focussing on the materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies. Chapters in part two examine applications in drug discovery and controlled-delivery including micro needles. Part three considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering. The final part of the book covers the applications of microfluidic devices in diagnostic sensing, including genetic analysis, low-cost bioassays, viral detection, and radio chemical synthesis. Microfluidic devices for biomedical applications is an essential reference for medical device manufacturers, scientists and researchers concerned with microfluidics in the field of biomedical applications and life-science industries. Discusses the fundamentals of microfluidics or lab-on-a-chip (LOC) and explores in detail a wide range of medical applications Considers materials and methods for microfabrication, microfluidic actuation mechanisms and digital microfluidic technologies Considers applications of microfluidic devices in cellular analysis and manipulation, tissue engineering and their role in developing tissue scaffolds and stem cell engineering

Microfluidics Based Microsystems Book

Microfluidics Based Microsystems


  • Author : S. Kakaç
  • Publisher : Springer
  • Release Date : 2010-06-30
  • Genre: Science
  • Pages : 618
  • ISBN 10 : 9789048190294

GET BOOK
Microfluidics Based Microsystems Book Description :

This volume contains an archival record of the NATO Advanced Study Institute on Microfluidics Based Microsystems – Fundamentals and App- cations held in Çe ?me-Izmir, Turkey, August 23–September 4, 2009. ASIs are intended to be high-level teaching activity in scientific and technical areas of current concern. In this volume, the reader may find interesting chapters and various microsystems fundamentals and applications. As the world becomes increasingly concerned with terrorism, early - spot detection of terrorist’s weapons, particularly bio-weapons agents such as bacteria and viruses are extremely important. NATO Public Diplomacy division, Science for Peace and Security section support research, Advanced Study Institutes and workshops related to security. Keeping this policy of NATO in mind, we made such a proposal on Microsystems for security. We are very happy that leading experts agreed to come and lecture in this important NATO ASI. We will see many examples that will show us Microfluidics usefulness for rapid diagnostics following a bioterrorism attack. For the applications in national security and anti-terrorism, microfluidic system technology must meet the challenges. To develop microsystems for security and to provide a comprehensive state-of-the-art assessment of the existing research and applications by treating the subject in considerable depth through lectures from eminent professionals in the field, through discussions and panel sessions are very beneficial for young scientists in the field.

Microfluidics and Nanotechnology Book

Microfluidics and Nanotechnology


  • Author : Eric Lagally
  • Publisher : CRC Press
  • Release Date : 2014-05-27
  • Genre: Medical
  • Pages : 290
  • ISBN 10 : 9781466594913

GET BOOK
Microfluidics and Nanotechnology Book Description :

An increasing number of technologies are being used to detect minute quantities of biomolecules and cells. However, it can be difficult to determine which technologies show the most promise for high-sensitivity and low-limit detection in different applications. Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit details proven approaches for the detection of single cells and even single molecules—approaches employed by the world’s foremost microfluidics and nanotechnology laboratories. While similar books concentrate only on microfluidics or nanotechnology, this book focuses on the combination of soft materials (elastomers and other polymers) with hard materials (semiconductors, metals, and glass) to form integrated detection systems for biological and chemical targets. It explores physical and chemical—as well as contact and noncontact—detection methods, using case studies to demonstrate system capabilities. Presenting a snapshot of the current state of the art, the text: Explains the theory behind different detection techniques, from mechanical resonators for detecting cell density to fiber-optic methods for detecting DNA hybridization, and beyond Examines microfluidic advances, including droplet microfluidics, digital microfluidics for manipulating droplets on the microscale, and more Highlights an array of technologies to allow for a comparison of the fundamental advantages and challenges of each, as well as an appreciation of the power of leveraging scalability and integration to achieve sensitivity at low cost Microfluidics and Nanotechnology: Biosensing to the Single Molecule Limit not only serves as a quick reference for the latest achievements in biochemical detection at the single-cell and single-molecule levels, but also provides researchers with inspiration for further innovation and expansion of the field.