Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies Book

Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies


  • Author : Tetsuya Watanabe
  • Publisher : Academic Press
  • Release Date : 2022-01-28
  • Genre: Science
  • Pages : 244
  • ISBN 10 : 9780323972703

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Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies Excerpt :

Modeling Electrochemical Dynamics and Signaling Mechanisms in Excitable Cells with Pathological Case Studies covers the neuronal cell communication system in excitable cells, recognizing the most relevant mechanisms of cell communication. Along with new findings in biotechnology, medicine and pathological cases for clinicians, the book highlights electrochemical potential in living nerve and muscle cells. Written for physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists, this book an essential read for a real understanding of the signals as we see them. Covers neuronal cell communication systems in excitable cells Presents new findings in biotechnology that are being applied in medicine and pathological cases Covers mathematical and physical bases for readers without background in these fields

Cumulated Index Medicus Book

Cumulated Index Medicus


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 1970
  • Genre: Medicine
  • Pages : null
  • ISBN 10 : OSU:32436001305117

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Cumulated Index Medicus Excerpt :

Essential Chemistry for Formulators of Semisolid and Liquid Dosages Book

Essential Chemistry for Formulators of Semisolid and Liquid Dosages


  • Author : Vitthal S. Kulkarni
  • Publisher : Academic Press
  • Release Date : 2015-10-15
  • Genre: Science
  • Pages : 256
  • ISBN 10 : 9780128010723

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Essential Chemistry for Formulators of Semisolid and Liquid Dosages Excerpt :

A needed resource for pharmaceutical scientists and cosmetic chemists, Essential Chemistry for Formulators of Semisolid and Liquid Dosages provides insight into the basic chemistry of mixing different phases and test methods for the stability study of nonsolid formulations. The book covers foundational surface/colloid chemistry, which forms the necessary background for making emulsions, suspensions, solutions, and nano drug delivery systems, and the chemistry of mixing, which is critical for further formulation of drug delivery systems into semisolid (gels, creams, lotions, and ointments) or liquid final dosages. Expanding on these foundational principles, this useful guide explores stability testing methods, such as particle size, rheological/viscosity, microscopy, and chemical, and closes with a valuable discussion of regulatory issues. Essential Chemistry for Formulators of Semisolid and Liquid Dosages offers scientists and students the foundation and practical guidance to make and analyze semisolid and liquid formulations. Unique coverage of the underlying chemistry that makes possible stable dosages Quality content written by experienced experts from the drug development industry Valuable information for academic and industrial scientists developing topical and liquid dosage formulations for pharmaceutical as well as skin care and cosmetic products

Voltage Gated Sodium Channels Book

Voltage Gated Sodium Channels


  • Author : Peter C. Ruben
  • Publisher : Springer Science & Business Media
  • Release Date : 2014-04-15
  • Genre: Medical
  • Pages : 295
  • ISBN 10 : 9783642415883

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Voltage Gated Sodium Channels Excerpt :

A number of techniques to study ion channels have been developed since the electrical basis of excitability was first discovered. Ion channel biophysicists have at their disposal a rich and ever-growing array of instruments and reagents to explore the biophysical and structural basis of sodium channel behavior. Armed with these tools, researchers have made increasingly dramatic discoveries about sodium channels, culminating most recently in crystal structures of voltage-gated sodium channels from bacteria. These structures, along with those from other channels, give unprecedented insight into the structural basis of sodium channel function. This volume of the Handbook of Experimental Pharmacology will explore sodium channels from the perspectives of their biophysical behavior, their structure, the drugs and toxins with which they are known to interact, acquired and inherited diseases that affect sodium channels and the techniques with which their biophysical and structural properties are studied.

Brain Research Institute UCLA Book

Brain Research Institute UCLA


  • Author : Anonim
  • Publisher : Unknown
  • Release Date : 2022-05-18
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : UCBK:C072208718

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Introduction to Environmental Forensics Book

Introduction to Environmental Forensics


  • Author : Brian L. Murphy
  • Publisher : Academic Press
  • Release Date : 2014-07-30
  • Genre: Science
  • Pages : 704
  • ISBN 10 : 9780124047075

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Introduction to Environmental Forensics Excerpt :

The third edition of Introduction to Environmental Forensics is a state-of-the-art reference for the practicing environmental forensics consultant, regulator, student, academic, and scientist, with topics including compound-specific isotope analysis (CSIA), advanced multivariate statistical techniques, surrogate approaches for contaminant source identification and age dating, dendroecology, hydrofracking, releases from underground storage tanks and piping, and contaminant-transport modeling for forensic applications. Recognized international forensic scientists were selected to author chapters in their specific areas of expertise and case studies are included to illustrate the application of these methods in actual environmental forensic investigations. This edition provides updates on advances in various techniques and introduces several new topics. Provides a comprehensive review of all aspects of environmental forensics Coverage ranges from emerging statistical methods to state-of-the-art analytical techniques, such as gas chromatography-combustion-isotope ratio mass spectrometry and polytopic vector analysis Numerous examples and case studies are provided to illustrate the application of these forensic techniques in environmental investigations

Calcium Entry Channels in Non Excitable Cells Book

Calcium Entry Channels in Non Excitable Cells


  • Author : Juliusz Ashot Kozak
  • Publisher : CRC Press
  • Release Date : 2017-07-14
  • Genre: Science
  • Pages : 328
  • ISBN 10 : 9781498752732

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Calcium Entry Channels in Non Excitable Cells Excerpt :

Calcium Entry Channels in Non-Excitable Cells focuses on methods of investigating the structure and function of non-voltage gated calcium channels. Each chapter presents important discoveries in calcium entry pathways, specifically dealing with the molecular identification of store-operated calcium channels which were reviewed by earlier volumes in the Methods in Signal Transduction series. Crystallographic and pharmacological approaches to the study of calcium channels of epithelial cells are also discussed. Calcium ion is a messenger in most cell types. Whereas voltage gated calcium channels have been studied extensively, the non-voltage gated calcium entry channel genes have only been identified relatively recently. The book will fill this important niche.

Calcium Signalling in Alzheimer   s Disease Book

Calcium Signalling in Alzheimer s Disease


  • Author : Mounia Chami
  • Publisher : MDPI
  • Release Date : 2021-04-22
  • Genre: Science
  • Pages : 162
  • ISBN 10 : 9783036504988

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Calcium Signalling in Alzheimer s Disease Excerpt :

Alzheimer’s disease (AD) is the most well-known neurodegenerative disorder, causing dementia. In recent decades, several studies have reported calcium dysregulation in AD occurring through the intervention of several calcium receptors and channels, and affecting different cellular compartments, such as mitochondria, the endoplasmic reticulum, lysosomes, and microdomains within the plasma membrane. Calcium signalling dysregulation is now considered a common proximal cause of dysfunctional neurons and glial supporting cells. This book gathers the newest results and advances in calcium signaling deregulation mechanisms in AD, how they are linked to other players involved in AD, and the potential therapies targeting calcium alterations to treat AD.

Essential Clinical Procedures E Book Book

Essential Clinical Procedures E Book


  • Author : Richard W. Dehn
  • Publisher : Elsevier Health Sciences
  • Release Date : 2020-01-10
  • Genre: Medical
  • Pages : 464
  • ISBN 10 : 9780323624688

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Essential Clinical Procedures E Book Excerpt :

Provide safe and effective care to every patient with the fully revised 4th Edition of Essential Clinical Procedures. Written by experts in the field, this widely used reference shows you step by step how to perform more than 70 of the most common diagnostic and treatment-related procedures in today’s primary care and specialist settings. You’ll find clear, concise coverage of the skills you need to know, including new and advanced procedures and new procedure videos. Covers patient preparation, the proper use of instruments, and potential dangers and complications involved in common procedures, as well as nonprocedural issues such as informed consent, standard precautions, patient education, and procedure documentation. Includes new chapters on Point-of-Care Ultrasound and Ring Removal, as well as 35 new procedure videos. Features significantly revised content on cryosurgery • injection techniques • arterial puncture • shoulder/finger subluxations • sterile technique • outpatient coding • casting and splinting • blood cultures • standard precautions • and more. Contains more than 200 high-quality illustrations, including updated images of office pulmonary function testing and wound closure. Uses a consistently formatted presentation to help you find information quickly. Reflects the latest evidence-based protocols and national and international guidelines throughout.

Physiology of Astroglia Book

Physiology of Astroglia


  • Author : Alexei Verkhratsky
  • Publisher : Biota Publishing
  • Release Date : 2015-03-01
  • Genre: Medical
  • Pages : 172
  • ISBN 10 : 9781615046737

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Physiology of Astroglia Excerpt :

Astrocytes can be defined as the glia inhabiting the nervous system with the main function in the maintenance of nervous tissue homeostasis. Classified into several types according to their morphological appearance, many of astrocytes form a reticular structure known as astroglial syncytium, owing to their coupling via intercellular channels organized into gap junctions. Not only do astrocytes establish such homocellular contacts, but they also engage in intimate heterocellular interactions with neurons, most notably at synaptic sites. As synaptic structures house the very core of information transfer and processing in the nervous system, astroglial perisynaptic positioning assures that these glial cells can nourish neurons and establish bidirectional communication with them, functions outlined in the concepts of the astrocytic cradle and multi-partite synapse, respectively. Astrocytes possess a rich assortment of ligand receptors, ion and water channels, and ion and ligand transporters, which collectively contribute to astrocytic control of homeostasis and excitability. Astroglia control glutamate and adenosine homeostasis to exert modulatory actions affecting the real-time operation of synapses. Fluctuations of intracellular calcium can lead to the release of various chemical transmitters from astrocytes through a process termed gliotransmission. Sodium fluctuations are closely associated to those of calcium with both dynamic events interfacing signaling and metabolism. Astrocytes appear fully integrated into the brain cellular circuitry, being an indispensable part of neural networks.

Visualizing Chemistry Book

Visualizing Chemistry


  • Author : National Research Council
  • Publisher : National Academies Press
  • Release Date : 2006-06-01
  • Genre: Science
  • Pages : 222
  • ISBN 10 : 030916463X

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Visualizing Chemistry Excerpt :

Scientists and engineers have long relied on the power of imaging techniques to help see objects invisible to the naked eye, and thus, to advance scientific knowledge. These experts are constantly pushing the limits of technology in pursuit of chemical imaging—the ability to visualize molecular structures and chemical composition in time and space as actual events unfold—from the smallest dimension of a biological system to the widest expanse of a distant galaxy. Chemical imaging has a variety of applications for almost every facet of our daily lives, ranging from medical diagnosis and treatment to the study and design of material properties in new products. In addition to highlighting advances in chemical imaging that could have the greatest impact on critical problems in science and technology, Visualizing Chemistry reviews the current state of chemical imaging technology, identifies promising future developments and their applications, and suggests a research and educational agenda to enable breakthrough improvements.

Modeling and Simulating Cardiac Electrical Activity Book

Modeling and Simulating Cardiac Electrical Activity


  • Author : Trine Krogh-Madsen
  • Publisher : IOP Publishing Limited
  • Release Date : 2020-12-03
  • Genre: Science
  • Pages : 236
  • ISBN 10 : 0750320621

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Modeling and Simulating Cardiac Electrical Activity Excerpt :

This book provides a thorough introduction to the topic of mathematical modeling of electrical activity in the heart, from molecular details of ionic channel dynamics to clinically derived patient-specific models. It discusses how cellular ionic models are formulated, introduces commonly used models and explains why there are so many different models available. The chapters cover modeling of the intracellular calcium handling that underlies cellular contraction as well as modeling molecular-level details of cardiac ion channels, and specialized topics such as cardiomyocyte energetics and signalling pathways. It is an excellent resource for experienced and specialized researchers in the field, but also biological scientists with a limited background in mathematical modelling and computational methods. Key Features Thorough introduction to the topic of mathematical modeling of electrical activity in the heart Focuses on use of experimental data in mathematical modeling, and on explanations rather than equations In addition to being experts in the field, the contributing authors are expert science communicators

The olivo cerebellar system Book

The olivo cerebellar system


  • Author : Egidio D'Angelo
  • Publisher : Frontiers Media SA
  • Release Date : 2016-04-29
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 9782889198269

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The olivo cerebellar system Excerpt :

During the last decades, investigations on the olivo-cerebellar system have attained a high level of sophistication, which led to redefinitions of several structural and functional properties of neurons, synapses, connections and circuits. Research has expanded and deepened in so many directions and so many theories and models have been proposed that an ensemble review of the matter is now needed. Yet, hot topics remain open and scientific discussion is very lively at several fronts. One major question, here as well as in other major brain circuits, is how single neurons and synaptic properties emerge at the network level and contribute to behavioural regulation via neuronal plasticity. Other major aspects that this Research Topic covers and discusses include the development and circuit organization of the olivo-cerebellar network, the established and recent theories of learning and motor control, and the emerging role of the cerebellum in cognitive processing. By touching on such varied and encompassing subjects, this Frontiers Special Topic aims to highlight the state of the art and stimulate future research. We hope that this unique collection of high-quality articles from experts in the field will provide scientists with a powerful basis of knowledge and inspiration to enucleate the major issues deserving further attention.

Neuroprosthetics Book
Score: 4
From 1 Ratings

Neuroprosthetics


  • Author : Kenneth W. Horch
  • Publisher : World Scientific
  • Release Date : 2004
  • Genre: Science
  • Pages : 1261
  • ISBN 10 : 9812380221

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Neuroprosthetics Excerpt :

A study of neuroprosthetics. It is broadly divided into three sections which address: neuroanatomy and neurophysiology, biomaterials and biocompatibility, stimulation and recording techniques; clinical applications of neuroprosthetics; and future developments.

Cell based Biosensors Book

Cell based Biosensors


  • Author : Qingjun Liu
  • Publisher : Artech House
  • Release Date : 2009-10-01
  • Genre: Biosensors
  • Pages : 271
  • ISBN 10 : 9781596934405

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Cell based Biosensors Excerpt :

Written by recognized experts the field, this leading-edge resource is the first book to systematically introduce the concept, technology, and development of cell-based biosensors. You find details on the latest cell-based biosensor models and novel micro-structure biosensor techniques. Taking an interdisciplinary approach, this unique volume presents the latest innovative applications of cell-based biosensors in a variety of biomedical fields. The book also explores future trends of cell-based biosensors, including integrated chips, nanotechnology and microfluidics. Over 140 illustrations help clarify key topics throughout the book.