Molecular Advancements in Tropical Diseases Drug Discovery Book
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Molecular Advancements in Tropical Diseases Drug Discovery


  • Author : Gauri Misra
  • Publisher : Academic Press
  • Release Date : 2020-05-12
  • Genre: Science
  • Pages : 154
  • ISBN 10 : 9780128213971

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Molecular Advancements in Tropical Diseases Drug Discovery Excerpt :

Molecular Advancements in Tropical Diseases Drug Discovery presents in-depth knowledge relating to the detection of infection, epidemiology, drugs against various tropical diseases, new target sites for drug discovery and multidrug resistance issues using bioinformatics tools and approaches. The book's chapters are written by experts in their respective fields so that each disease is covered in a rational manner and with a solid foundation on existing facts and prospective research ideas. Updates knowledge about tropical diseases with recent advancements in the field Presents an overview of new research covering detection, infection, epidemiology and risk factors of the most common tropical diseases using bioinformatics tools Encompasses a detailed description of developments in drug discovery, new drugs and their molecular mechanisms of action

Neglected Tropical Diseases and Phytochemicals in Drug Discovery Book

Neglected Tropical Diseases and Phytochemicals in Drug Discovery


  • Author : Chukwuebuka Egbuna
  • Publisher : John Wiley & Sons
  • Release Date : 2021-11-09
  • Genre: Science
  • Pages : 628
  • ISBN 10 : 9781119616603

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Neglected Tropical Diseases and Phytochemicals in Drug Discovery Excerpt :

NEGLECTED TROPICAL DISEASES AND PHYTOCHEMICALS IN DRUG DISCOVERY Explore novel drug discovery updates from medicinal plants to help fight the devastating effects of neglected tropical diseases Neglected Tropical Diseases and Phytochemicals in Drug Discovery delivers a comprehensive exploration of the drug discovery process as it pertains to neglected tropical diseases. The book covers recent advancements in drug discovery, as well as druggable targets and new challenges facing the industry. It offers readers expansive discussions of specific diseases, including protozoan, helminth, bacterial, viral, fungal, and ectoparasitic infections. This book provides readers with insightful perspectives from leading industry voices on fifty years of trends and progress in the search for new, safe, and affordable therapeutic drugs in the fight against neglected tropical diseases. It includes information beneficial to researchers in a variety of fields of biology, chemistry, medicine, and pharmaceuticals. The distinguished authors cover topics including the effects of phytochemicals on the causative agent of leprosy and the potential applicability of phytochemicals in the management of Dengue fever. Readers will also enjoy the inclusion of: Thorough introductions to neglected tropical diseases, phytochemicals, protein targets, and mechanisms in drug discovery, as well as the epidemiology of neglected tropical diseases An exploration of novel bioactive lead compounds for drug discovery against neglected tropical diseases, leishmaniasis, lymphatic filariasis, trypanosomiasis, and schistosomiasis Discussions of protozoan infections, including herbal, nutritional, and traditional remedies for giardiasis and the anti-leishmanial potentials of phytochemicals Examinations of helminth infections, including the prospects of phytochemicals in the treatment of helminthiasis Perfect for medicinal chemists, drug developers, and research and development scientists, Neglected Tropical Diseases

Drug Discovery for Leishmaniasis Book

Drug Discovery for Leishmaniasis


  • Author : Carmen Gil
  • Publisher : Royal Society of Chemistry
  • Release Date : 2017-11-02
  • Genre: Science
  • Pages : 422
  • ISBN 10 : 9781782628897

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Drug Discovery for Leishmaniasis Excerpt :

For human health, leishmaniasis is among the most important protozoan diseases, superseded only by malaria. Globally, 10 to 12 million people are infected with 1.5 million new cases every year. The development of cheaper new drugs is urgently needed for this neglected disease that is developing resistance to current treatments. Chemotherapy remains the only treatment option for the bulk of patients. However, this is largely unaffordable for most. In the past three years numerous advances in drug discovery have been made for treating this disease by exploiting diverging metabolic pathways between the Leishmania enzymes and their hosts, using nanotechnology to target the immune cell phagolysosomes where Leishmania resides. Drug Discovery for Leishmaniasis aims to provide a perspective of the current treatments and their challenges, blended with the emerging strategies and methodologies that will drive new target appraisals and drug developments, as well as addressing the molecular basis of resistance in Leishmania. Recent studies have shown that leishmaniasis affects some of the poorest people in the world, with 95% of fatal cases occurring in only 6 countries. With the WHO goal of eliminating this public health problem in the South-east Asia Region by 2020, this book will be important for anyone who is interested in neglected tropical diseases.

Current Topics and Emerging Issues in Malaria Elimination Book

Current Topics and Emerging Issues in Malaria Elimination


  • Author : Anonim
  • Publisher : BoD – Books on Demand
  • Release Date : 2021-07-21
  • Genre: Medical
  • Pages : 336
  • ISBN 10 : 9781839684838

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Current Topics and Emerging Issues in Malaria Elimination Excerpt :

Malaria is one of the most important tropical diseases in the history of the world. This vector-borne disease has been a significant cause of morbidity and mortality in tropical countries of Africa, Asia, and Latin America. As such, this book provides updated information on epidemiological and public health research of malaria conducted in the last decade. Over four sections, chapters discuss such topics as diagnosis, epidemiology and surveillance, policy and prevention, and vector control and vaccines.

Design of Hybrid Molecules for Drug Development Book

Design of Hybrid Molecules for Drug Development


  • Author : Michael Decker
  • Publisher : Elsevier
  • Release Date : 2017-04-05
  • Genre: Science
  • Pages : 352
  • ISBN 10 : 9780081011188

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Design of Hybrid Molecules for Drug Development Excerpt :

Design of Hybrid Molecules for Drug Development reviews the principles, advantages, and limitations involved with designing these groundbreaking compounds. Beginning with an introduction to hybrid molecule design and background as to their need, the book goes on to explore a range of important hybrids, with hybrids containing natural products, molecules containing NO- and H2S-donors, dual-acting compounds acting as receptor ligands and enzyme inhibitors, and the design of photoresponsive drugs all discussed. Drawing on practical case studies, the hybridization of molecules for development as treatments for a number of key diseases is then outlined, including the design of hybrids for Alzheimer's, cancer, and malaria. With its cutting-edge reviews of breaking developments in this exciting field, the book offers a novel approach for all those working in the design, development, and administration of drugs for a range of debilitating disorders. Highlights an approach unimpaired by the limitations of the classical search for lead structures - one of the core problems in modern drug development processes, making the content of high relevance for both academic and non-academic drug development processes Pulls together research and design techniques in a novel way to give researchers the best possible platform from which to review the approaches and techniques applied Compares the advantages and disadvantages of these compounds Includes the very latest developments, such as photoactivatable and photo-responsive drugs

Medicinal Chemistry of Neglected and Tropical Diseases Book

Medicinal Chemistry of Neglected and Tropical Diseases


  • Author : Venkatesan Jayaprakash
  • Publisher : CRC Press
  • Release Date : 2019-08-15
  • Genre: Medical
  • Pages : 461
  • ISBN 10 : 9781351011631

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Medicinal Chemistry of Neglected and Tropical Diseases Excerpt :

Medicinal Chemistry of Neglected and Tropical Diseases: Advances in the Design and Synthesis of Antimicrobial Agents consolidates and describes modern drug discovery and development approaches currently employed to identify effective chemotherapeutic agents for the treatment of Neglected Tropical Diseases (NTDs) from a medicinal chemistry perspective. Chapters are designed to cater to the needs of medicinal chemists who work with chemotherapeutic developments for NTDs, as well as serve as a guide to budding medicinal chemists who wish to work in this area. It will introduce rational drug design approaches adopted in designing chemotherapeutics and validated targets available for the purpose.

Drug Discovery and Development Book

Drug Discovery and Development


  • Author : Omboon Vallisuta
  • Publisher : BoD – Books on Demand
  • Release Date : 2015-06-03
  • Genre: Medical
  • Pages : 332
  • ISBN 10 : 9789535121282

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Drug Discovery and Development Excerpt :

It is very important for scientists all over the globe to enhance drug discovery research for better human health. This book demonstrates that various expertise are essential for drug discovery including synthetic or natural drugs, clinical pharmacology, receptor identification, drug metabolism, pharmacodynamic and pharmacokinetic research. The following 5 sections cover diverse chapter topics in drug discovery: Natural Products as Sources of Leading Molecules in Drug Discovery; Oncology and Drug Discovery; Receptors Involvement in Drug Discovery; Management and Development of Drugs against Infectious Diseases; Advanced Methodology.

Pathogenesis  Treatment and Prevention of Leishmaniasis Book

Pathogenesis Treatment and Prevention of Leishmaniasis


  • Author : Mukesh Samant
  • Publisher : Academic Press
  • Release Date : 2021-08-18
  • Genre: Medical
  • Pages : 280
  • ISBN 10 : 9780128227985

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Pathogenesis Treatment and Prevention of Leishmaniasis Excerpt :

Leishmaniasis is a neglected tropical disease that is known to be transmitted by 90 different species of sandflies which carry 20 Leishmania species that cause human infection particularly in endemic countries. Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to provide information on this vector-borne disease and explore strategies for diagnosis and treatment. The book begins with an overview of leishmaniasis which includes historical and future perspectives of the disease. It also discusses the clinical manifestation of the disease, mechanisms of infection, therapeutic strategies, diagnostics, prevention, and cure of Leishmania parasite. The book goes on to explain new insights and challenges in the development of promising drug targets, biomarkers identification and advance vaccination strategies against leishmaniasis. Chapter contributions brings together diverse areas of expertise making Pathogenesis, Treatment, and Prevention of Leishmaniasis aims to bring together elements of leishmaniasis into one place and be a valuable resource for researchers, health care professionals, and graduate students, working in the field of leishmaniasis. Provides an overview Leishmania and leishmanisis which include its history, transmission, clinical picture, and treatment Discusses novel approaches to study parasite infection and treatment Explores recent advances in the development of diagnostic kits, drug development and various vaccination strategies

Proceedings of 2nd International Conference on Advances in Chemical Engineering   Technology 2017 Book

Proceedings of 2nd International Conference on Advances in Chemical Engineering Technology 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2023-01-27
  • Genre: Uncategoriezed
  • Pages : 83
  • ISBN 10 : 978186723xxxx

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Proceedings of 2nd International Conference on Advances in Chemical Engineering Technology 2017 Excerpt :

November 16-17, 2017 Paris, France key Topics : Chemical engineering, Catalysis Engineering, Biologically Engineered Systems, Bio Fuels, Biotechnology, Biomaterials, Water Technology and Innovation, Polymer Technology, Thermodynamic Process, Seperation Techniques, Biochemical Engineering, Transport Phenomenon, Fluid Dynamics, Chemical reaction Engineering, Petroleum Engineering, Safety Methods, Enterpreneurship Investment Meet, Carbon and Graphene Materials, Environmental Engineering,

Proceedings of 3rd International Conference and Exhibition on Advances in Chromatography   HPLC Techniques 2017 Book

Proceedings of 3rd International Conference and Exhibition on Advances in Chromatography HPLC Techniques 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2023-01-27
  • Genre: Uncategoriezed
  • Pages : 73
  • ISBN 10 : 978186723xxxx

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Proceedings of 3rd International Conference and Exhibition on Advances in Chromatography HPLC Techniques 2017 Excerpt :

July 13-14, 2017 Berlin, Germany Key Topics : Major Chromatographic Techniques, HPLC Separation Techniques, Advances in HPLC Instrumentations, Hyphenated HPLC Methods, Chip Based Separations, High Efficiency and High Resolution Techniques, Method Development and Validation, Applications of HPLC, Biochemical Applications, HPLC Fingerprinting in Bioinformatics and Computational Biology, Recent Advances in HPLC, Market growth of HPLC

Imidazole Based Drug Discovery Book

Imidazole Based Drug Discovery


  • Author : Shikha Agarwal
  • Publisher : Elsevier
  • Release Date : 2021-12-10
  • Genre: Science
  • Pages : 372
  • ISBN 10 : 9780323903639

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Imidazole Based Drug Discovery Excerpt :

Imidazole-Based Drug Discovery covers all categories of imidazole and its derivatives, synthesis, pharmacological applications and drug-based studies. Imidazole scaffolds act as a channel between organic synthesis and medicinal chemistry and compel researchers to explore new drug candidates. This book provides detailed coverage of several greener synthetic protocols and pharmacological applications of imidazole derivatives that are useful to researchers working on designing more promising clinical lead compounds with this scaffold. It also includes information on past decades of research on the synthesis and biological applications of imidazole derivatives. This is an ideal resource for researchers in organic chemistry both in academic and industrial settings, as well as postgraduates in chemistry and medicinal chemistry. Reviews the most current developments and future perspectives of imidazole on different disease therapies to achieve the ultimate goal of disease eradication Discusses the role of imidazole in contemporary science, technological innovation, drug development, critical challenges and future research directions Covers emerging trends on different eco-benign pathways to synthesize imidazole derivatives for the development of simpler synthetic protocols

Proceedings of 6th World Congress on Medicinal Chemistry and Drug Design 2017 Book

Proceedings of 6th World Congress on Medicinal Chemistry and Drug Design 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2017-06-01
  • Genre: Medical
  • Pages : 95
  • ISBN 10 : 978186723xxxx

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Proceedings of 6th World Congress on Medicinal Chemistry and Drug Design 2017 Excerpt :

June 07-08, 2017 Milan,. Italy Key Topics : Medicinal Chemistry, Synthetic Organic Chemistry, Drug Design and Drug Development, CADD (Computer Aided Drug Design), Bioorganic and Medicinal Chemistry, Pharmacology and toxicology, BioInorganic Chemistry, Organometallic Chemistry, Radiopharmaceuticals, Chemical Biology, Anticancer agents in Medicinal Chemistry, Pharmaceutical Industry, Clinical Pharmacology, Pharmaceutical Sciences, Bioisostere, Analytical Chemistry, Nanomedicine, Stereochemistry, Pharmacovigilance,

Proceedings of 6th Euro Global Conference on Infectious Diseases 2017 Book

Proceedings of 6th Euro Global Conference on Infectious Diseases 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2023-01-27
  • Genre: Uncategoriezed
  • Pages : 85
  • ISBN 10 : 978186723xxxx

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Proceedings of 6th Euro Global Conference on Infectious Diseases 2017 Excerpt :

September 07-09, 2017 Paris, France Key Topics : Viral Infectious Diseases, Bacterial Infectious Diseases, Ebola Outbreak and Approaches for Prevention, Fungal Infectious Diseases, New Antiviral, Antibacterial and Antifungal Agents, Market Trends Of Infectious Diseases, Parasitic Diseases, Bacterial Susceptibility & Resistance, Nosocomial Infections, Detection and preventing infections in healthcare, Public health practice, Vaccines, Respiratory Diseases, Infectious Agents and the Human Immune Response, Infectious Diseases: Worms, Prions, and Fungi, Protozoal Diseases, Clinical Infectious Disease, Infectious Disease Epidemiology, Emerging Infectious Diseases, Laboratory Diagnosis of Infectious Diseases, Infectious Diseases of Humans, Infectious Diseases and Pathology, Microbiology and Infectious Diseases, Infectious Diseases of Livestock, Infectious Diseases of the Female Genital Tract, Molecular Diagnostics of Infectious Diseases, Pediatric Infectious Diseases, Bacterial Genomes and Infectious Diseases:, Drug Interactions in Infectious Diseases, Infectious Diseases in Children, Medical Pioneers in Infectious Diseases, Infectious Diseases and Tropical Medicine, Infectious Diseases in Critical Care Medicine, Infectious Diseases and Arthropods, Preventing Infectious Diseases, Feline Infectious Diseases, Tropical Infectious Diseases, Infectious Diseases in America, Infectious Diseases in Europe, Infectious Diseases in UK, Infectious Diseases in Asia, Infectious Diseases in Africa, Sexually transmitted Diseases and infection,

Proceedings of 4th International congress on Infectious Diseases 2017 Book

Proceedings of 4th International congress on Infectious Diseases 2017


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2023-01-27
  • Genre: Uncategoriezed
  • Pages : 77
  • ISBN 10 : 978186723xxxx

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Proceedings of 4th International congress on Infectious Diseases 2017 Excerpt :

May 11-12, 2017 Barcelona, Spain Key Topics : Infection and Immune System, Host and Microbial Genetics, Infections from Contaminated Pharmaceuticals or Counterfeit Medications, Foodborne & Waterborne Illnesses, Nosocomial Infections, Pediatric Infections, Emergence and Pathogenesis of Coronaviruses, Hemorrhagic Fevers, New or Rapid Diagnostics, Therapeutic Interventions in Rare Diseases, Antimicrobial Resistance, Drug metabolism in microorganisms, Infection Control and Epidemiology, New Opportunities for Tuberculosis Control,

Proceedings of 20th International Conference on Advanced Energy Materials and Research 2018 Book

Proceedings of 20th International Conference on Advanced Energy Materials and Research 2018


  • Author : ConferenceSeries
  • Publisher : ConferenceSeries
  • Release Date : 2018-08-07
  • Genre: Education
  • Pages : 117
  • ISBN 10 : 978186723xxxx

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Proceedings of 20th International Conference on Advanced Energy Materials and Research 2018 Excerpt :

August 13-14 2018 Dublin, Ireland Key Topics : Advanced Energy Materials, Hydrogen Energy, Solar Energy Materials, Polymer Materials, Advanced Nanomaterials, Energy Harvesting Materials, Nanotechnology and Energy Materials, Batteries and Energy Materials, Electric, Hybrid, and Fuel-Cell Vehicles, Mining, Metallurgy & Materials Science, Advanced Graphene Materials, Solid Electrolytes, Biomaterials and Surface Science Engineering, Electrical, Optical and Magnetic Materials, Fuel Cell Technology,