Molecular Neurology Book

Molecular Neurology


  • Author : Stephen Waxman
  • Publisher : Elsevier
  • Release Date : 2010-07-26
  • Genre: Medical
  • Pages : 600
  • ISBN 10 : 0080546188

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Molecular Neurology Excerpt :

Why a book on molecular neurology? Molecular neuroscience is advancing at a spectacular rate. As it does so, it is revealing important clues to the pathogenesis and pathophysiology of neurological diseases, and to the therapeutic targets that they present. Medicines work by targeting molecules. The more specific the targeting, the more specific the actions, and the fewer the side effects. Molecular Neurology highlights, for graduate and MD-PhD students, research fellows and research-oriented clinical fellows, and researchers in the neurosciences and other biomedical sciences, the principles underlying molecular medicine as related to neurology. Written by internationally recognized experts, this well-illustrated and well-referenced book presents the most up-to-date principles and disease examples relevant to molecular neurology, and reviews the concepts, strategies, and latest progress in this field. This book will interest anyone studying the molecular basis of neurology, or developing new therapies in neurology. Describes the newest molecular aspects of neurological disorders Provides an introduction to neurological disorders for basic scientists Updates clinicians and clinical researchers on the most recent developments

From Molecules to Networks Book
Score: 5
From 1 Ratings

From Molecules to Networks


  • Author : Ruth Heidelberger
  • Publisher : Elsevier
  • Release Date : 2003-11-10
  • Genre: Medical
  • Pages : 583
  • ISBN 10 : 0080491359

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From Molecules to Networks Excerpt :

An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. This book provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells that is needed by advanced undergraduates and graduate students, as well as researchers in need of a thorough reference. * Highly referenced for readers to pursue topics of interest in greater detail * Unique coverage of the application of mathematical modeling and simulation approaches not found in other textbooks * Richly illustrated, four color presentation throughout * Includes CD-ROM of all of the illustrations

Molecular Neuroscience Book

Molecular Neuroscience


  • Author : Dr P Revest
  • Publisher : Garland Science
  • Release Date : 1998-06-15
  • Genre: Science
  • Pages : null
  • ISBN 10 : 9781135321468

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Molecular Neuroscience Excerpt :

The Molecular Biology of Neurological Disease Book

The Molecular Biology of Neurological Disease


  • Author : Roger N. Rosenberg
  • Publisher : Butterworth-Heinemann
  • Release Date : 2013-10-22
  • Genre: Health & Fitness
  • Pages : 276
  • ISBN 10 : 9781483163307

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The Molecular Biology of Neurological Disease Excerpt :

The Molecular Biology of Neurological Disease reviews advances that have been made in understanding the molecular mechanisms of neurological disorders as well as immediate and future applications of molecular biological techniques to clinical practice. This book explores the molecular genetics of neurological disease such as muscular dystrophy, Joseph disease, and Huntington's disease, along with the mitochondrial genes implicated in such conditions. This text is comprised of 18 chapters and begins by introducing the reader to the basic principles and methods of molecular genetic techniques used in the diagnosis of neurological disease. Attention then turns to several aspects of genetic expression in the brain, including the extent to which the genome is expressed in the brain. The next chapter focuses on the visualization of polyadenylated messenger RNAs in individual cells in mammalian brain using in situ hybridization techniques, combined with immunohistochemical localization of specific proteins and neuropeptides implicated in diseases such as Alzheimer dementia. This book also discusses the molecular biology of chemical synaptic neurotransmission; proteins involved in the regulation of nervous system development; and gene expression in skeletal muscle. This text then concludes with a summary of the ""neurological gene map"" as it stands in the latter part of 1987. This book is intended for physicians who grapple with the problems of neurological disorders on a daily basis, including neurologists, neurologists in training, and those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Book

Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease


  • Author : Roger N. Rosenberg
  • Publisher : Elsevier
  • Release Date : 2014-10-28
  • Genre: Medical
  • Pages : 1464
  • ISBN 10 : 9780124105492

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Rosenberg s Molecular and Genetic Basis of Neurological and Psychiatric Disease Excerpt :

Rosenberg’s Molecular and Genetic Basis of Neurologic and Psychiatric Disease, Fifth Edition provides a comprehensive introduction and reference to the foundations and key practical aspects relevant to the majority of neurologic and psychiatric disease. A favorite of over three generations of students, clinicians and scholars, this new edition retains and expands the informative, concise and critical tone of the first edition. This is an essential reference for general medical practitioners, neurologists, psychiatrists, geneticists, and related professionals, and for the neuroscience and neurology research community. The content covers all aspects essential to the practice of neurogenetics to inform clinical diagnosis, treatment and genetic counseling. Every chapter has been thoroughly revised or newly commissioned to reflect the latest scientific and medical advances by an international team of leading scientists and clinicians. The contents have been expanded to include disorders for which a genetic basis has been recently identified, together with abundant original illustrations that convey and clarify the key points of the text in an attractive, didactic format. Previous editions have established this book as the leading tutorial reference on neurogenetics. Researchers will find great value in the coverage of genomics, animal models and diagnostic methods along with a better understanding of the clinical implications. Clinicians will rely on the coverage of the basic science of neurogenetics and the methods for evaluating patients with biochemical abnormalities or gene mutations, including links to genetic testing for specific diseases. Comprehensive coverage of the neurogenetic foundation of neurological and psychiatric disease Detailed introduction to both clinical and basic research implications of molecular and genetic understanding of the brain Detailed coverage of genomics, animal models and diagnostic methods with new coverage of evaluating patients wit

The Molecular Immunology of Neurological Diseases Book

The Molecular Immunology of Neurological Diseases


  • Author : Sunil Kumar
  • Publisher : Academic Press
  • Release Date : 2021-02-16
  • Genre: Medical
  • Pages : 176
  • ISBN 10 : 9780128232545

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The Molecular Immunology of Neurological Diseases Excerpt :

The Molecular Immunology of Neurological Diseases provides a comprehensive review of current updates in molecular immunogenetics of different neurological diseases. Readers will learn about the role of immune cells and their modulation strategies to help in the development of therapeutic approaches for both acute and chronic neurodegenerative disorders. There is no other book available on the topic. It has long been thought that the brain is an immune-privilege organ with very limited immune response. However recent studies have made clear that both systemic 'brain' and peripheral 'blood' immune cell responses play key roles in determining brain pathology in neurodegenerative disorders. This book summarizes the role of immune cell activation in the central nervous system microenvironment in acute and chronic neurodegenerative disorders. In addition, it discusses the key role of immune cells and their modulation strategies for the development of current therapeutic approaches. Discusses the molecular immunogenetics of different neurological diseases Covers strategies for the development of therapeutic approaches Encompasses both acute and chronic neurogenerative disorders Describes the molecular pathogenesis of viral genes in various diseases Features chapters on migraine, muscular dystrophy and cancer

From Molecules to Networks Book

From Molecules to Networks


  • Author : John H. Byrne
  • Publisher : Academic Press
  • Release Date : 2014-05-23
  • Genre: Science
  • Pages : 694
  • ISBN 10 : 9780123982674

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From Molecules to Networks Excerpt :

An understanding of the nervous system at virtually any level of analysis requires an understanding of its basic building block, the neuron. The third edition of From Molecules to Networks provides the solid foundation of the morphological, biochemical, and biophysical properties of nerve cells. In keeping with previous editions, the unique content focus on cellular and molecular neurobiology and related computational neuroscience is maintained and enhanced. All chapters have been thoroughly revised for this third edition to reflect the significant advances of the past five years. The new edition expands on the network aspects of cellular neurobiology by adding new coverage of specific research methods (e.g., patch-clamp electrophysiology, including applications for ion channel function and transmitter release; ligand binding; structural methods such as x-ray crystallography). Written and edited by leading experts in the field, the third edition completely and comprehensively updates all chapters of this unique textbook and insures that all references to primary research represent the latest results. The first treatment of cellular and molecular neuroscience that includes an introduction to mathematical modeling and simulation approaches 80% updated and new content New Chapter on "Biophysics of Voltage-Gated Ion Channels" New Chapter on "Synaptic Plasticity" Includes a chapter on the Neurobiology of Disease Highly referenced, comprehensive and quantitative Full color, professional graphics throughout All graphics are available in electronic version for teaching purposes

Fundamental Neuroscience Book
Score: 4
From 8 Ratings

Fundamental Neuroscience


  • Author : Larry Squire
  • Publisher : Elsevier
  • Release Date : 2002-11-19
  • Genre: Medical
  • Pages : 1426
  • ISBN 10 : 9780080521800

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Fundamental Neuroscience Excerpt :

With over 300 training programs in neuroscience currently in existence, demand is great for a comprehensive textbook that both introduces graduate students to the full range of neuroscience, from molecular biology to clinical science, but also assists instructors in offering an in-depth course in neuroscience to advanced undergraduates. The second edition of Fundamental Neuroscience accomplishes all this and more. The thoroughly revised text features over 25% new material including completely new chapters, illustrations, and a CD-ROM containing all the figures from the text. More concise and manageable than the previous edition, this book has been retooled to better serve its audience in the neuroscience and medical communities. Key Features * Logically organized into 7 sections, with uniform editing of the content for a "one-voice" feel throughout all 54 chapters * Includes numerous text boxes with concise, detailed descriptions of specific experiments, disorders, methodological approaches, and concepts * Well-illustrated with over 850 full color figures, also included on the accompanying CD-ROM

Molecular Aspects of Neurodegeneration and Neuroprotection Book

Molecular Aspects of Neurodegeneration and Neuroprotection


  • Author : Akhlaq A. Farooqui
  • Publisher : Bentham Science Publishers
  • Release Date : 2011-01-26
  • Genre: Science
  • Pages : 146
  • ISBN 10 : 9781608050925

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Molecular Aspects of Neurodegeneration and Neuroprotection Excerpt :

"Neurodegenerative diseases are a complex heterogeneous group of diseases associated with site-specific premature and slow death of certain neuronal populations in brain and spinal cord tissues. For example, in Alzheimer disease, neuronal degeneration occu"

Basic Neurochemistry Book
Score: 3.5
From 2 Ratings

Basic Neurochemistry


  • Author : Scott T. Brady
  • Publisher : Academic Press
  • Release Date : 2012
  • Genre: Medical
  • Pages : 1096
  • ISBN 10 : 9780123749475

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Basic Neurochemistry Excerpt :

Includes bibliographical references and index.

From Neuroscience to Neurology Book

From Neuroscience to Neurology


  • Author : Stephen Waxman
  • Publisher : Elsevier
  • Release Date : 2004-11-05
  • Genre: Medical
  • Pages : 552
  • ISBN 10 : 9780080506982

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From Neuroscience to Neurology Excerpt :

The field of neurology is being transformed, from a therapeutically nihilistic discipline with few effective treatments, to a therapeutic specialty which offers new, effective treatments for disorders of the brain and spinal cord. This remarkable transformation has bridged neuroscience, molecular medicine, and clinical investigation, and represents a major triumph for biomedical research. This book, which contains chapters by more than 29 internationally recognized authorities who have made major contributions to neurotherapeutics, tells the stories of how new treatments for disabling disorders of the nervous system, such as stroke, multiple sclerosis, Parkinson’s disease, and migraine, were developed, and explores evolving themes and technologies that offer hope for even more effective treatments and ultimately cures for currently untreatable disorders of the brain and spinal cord. The first part of this book reviews the development of new therapies in neurology, from their inception in terms of basic science to their introduction into the clinical world. It also explores evolving themes and new technologies. This book will be of interest to everyone – clinicians and basic scientists alike – interested in diseases of the brain and spinal cord, and in the quest for new treatments for these disorders. * Presents the evolution of the field of neurology into a therapeutic discipline * Discusses lessons learned from past successes and applications to ongoing work * Explores the future of this field

Molecular  Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease Book

Molecular Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease


  • Author : Robert J. Harvey
  • Publisher : Frontiers Media SA
  • Release Date : 2017-07-05
  • Genre: Uncategoriezed
  • Pages : null
  • ISBN 10 : 9782889451739

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Molecular Cellular and Model Organism Approaches for Understanding the Basis of Neurological Disease Excerpt :

The advent of next-generation sequencing technologies has resulted in a remarkable increase our understanding of human and animal neurological disorders through the identification of disease causing or protective sequence variants. However, in many cases, robust disease models are required to understand how changes at the DNA, RNA or protein level affect neuronal and synaptic function, or key signalling pathways. In turn, these models may enable understanding of key disease processes and the identification of new targets for the medicines of the future. This e-book contains original research papers and reviews that highlight either the impact of next-generation sequencing in the understanding of neurological disorders, or utilise molecular, cellular, and whole-organism models to validate disease-causing or protective sequence variants.

Neuropeptides Book
Score: 5
From 1 Ratings

Neuropeptides


  • Author : Fleur L. Strand
  • Publisher : MIT Press
  • Release Date : 1999
  • Genre: Medical
  • Pages : 658
  • ISBN 10 : 0262194074

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Neuropeptides Excerpt :

This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. In recent years there has been increasing interest and, subsequently, active research in neuropeptides. These neuroactive molecules coordinate, integrate, and regulate physiological processes in all organisms, throughout all phases of development. Acting as neurohormones, neurotransmitters, and/or neuromodulators, they maintain physiological homeostasis and influence important behavioral patterns. This textbook is the first to bring together and synthesize the neuropeptide research of the past decade in such a comprehensive, scholarly manner. The book is divided into two parts. In Part I the author defines the basic principles of neuropeptide action, including their biosynthesis, processing, transport, distribution, and interactions with receptors and second messenger systems. Strand also discusses the intimate interaction between the neuropeptides, stress, and the immune system. In Part II she discusses the regulatory functions of the families of neuropeptide in sufficient detail to provide both the advanced student and senior investigator with a thorough understanding of the most important neuropeptides. The text also contains a complete and up-to-date reference/reading list.