Mucosal Vaccines Book

Mucosal Vaccines


  • Author : Hiroshi Kiyono
  • Publisher : Elsevier
  • Release Date : 1996-10-23
  • Genre: Medical
  • Pages : 479
  • ISBN 10 : 0080537057

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Mucosal Vaccines Excerpt :

This comprehensive, authoritative treatise covers all aspects of mucosal vaccines including their development, mechanisms of action, molecular/cellular aspects, and practical applications. The contributing authors and editors of this one-of-a-kind book are very well known in their respective fields. Mucosal Vaccines is organized in a unique format in which basic, clinical, and practical aspects of the mucosal immune system for vaccine development are described and discussed. This project is endorsed by the Society for Mucosal Immunology. Provides the latest views on mucosal vaccines Applies basic principles to the development of new vaccines Links basic, clinical, and practical aspects of mucosal vaccines to different infectious diseases Unique and user-friendly organization

Mucosal Vaccines Book

Mucosal Vaccines


  • Author : David W. Pascual
  • Publisher : Academic Press
  • Release Date : 2019-10-19
  • Genre: Medical
  • Pages : 940
  • ISBN 10 : 9780128119259

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Mucosal Vaccines Excerpt :

Mucosal Vaccines: Innovation for Preventing Infectious Diseases discusses basic knowledge and discovery in the area of mucosal immunology and its related scientific fields. This completely updated, revised and authoritative treatise covers all aspects of mucosal vaccines, including their development, mechanisms of action, molecular/cellular aspects and practical applications. The book is organized in a unique format with basic, clinical and practical aspects described and discussed. The accumulated knowledge and new discoveries on the development of mucosal vaccines are logically introduced and discussed in an easy-to-understand format. Provides the latest views on mucosal vaccines Applies basic and current principles in the field of mucosal immunology and related scientific fields (e.g., microbiology, infectious diseases, systems biology, medicine, dentistry, veterinary medicine and translational research) to the development of new vaccines Links basic, clinical and practical aspects of mucosal vaccines to different infectious diseases Presents user-friendly organization using attractive illustrations

Mucosal Vaccines Book

Mucosal Vaccines


  • Author : Pamela A. Kozlowski
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-13
  • Genre: Medical
  • Pages : 198
  • ISBN 10 : 9783642236921

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Mucosal Vaccines Excerpt :

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.

Mucosal Vaccines Book

Mucosal Vaccines


  • Author : Pamela A. Kozlowski
  • Publisher : Springer Science & Business Media
  • Release Date : 2012-01-11
  • Genre: Medical
  • Pages : 198
  • ISBN 10 : 9783642236938

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Mucosal Vaccines Excerpt :

This volume is focused on the development of vaccines which generate immune effectors capable of blocking mucosal entry or peripheral pathogen spread. A critical first step in the design of mucosal vaccines is the selection of administration route. Not all mucosal immunization routes are created equally when it comes to eliciting immune responses in multiple body compartments. This subject and situations when a mucosal route may not be required for vaccine delivery are reviewed here with an emphasis on the sublingual immunization route, which may offer a safer alternative to the nasal route for induction of broadly disseminated immune responses. External host defenses that inhibit entry of microorganisms at mucosal surfaces also pose obstacles to the efficient internalization of mucosally-applied vaccines. Transcutaneous immunization with appropriate adjuvants and permeation enhancers can induce mucosal immune responses and may be advantageous for bypassing these luminal barriers. Other chapters describe strategies for enhancing uptake of mucosal vaccines, for instance through targeted delivery to antigen-sampling M cells, construction of virus-like particles which mimic natural pathogens, addition of mucoadhesives or formulation as nanoparticles. Topics include edible vaccines as well as plant-based production of subunit or particulate vaccines that could be administered by any route. Dry powder vaccines that could be insufflated or directly applied to mucosal surfaces may be particularly ideal for mass vaccination in developing countries. The manufacture, stability and efficacy of powder formulations is comprehensively reviewed. We conclude with chapters on two of the greatest challenges facing mucosal vaccine development: human immunodeficiency virus and bioterrorist agents. This monograph highlights progress and information that should prove invaluable for the development of contemporary vaccines that prevent infection by these and other mucosal pathogens.

Mucosal Health in Aquaculture Book

Mucosal Health in Aquaculture


  • Author : Benjamin H. Beck
  • Publisher : Academic Press
  • Release Date : 2015-02-17
  • Genre: Technology & Engineering
  • Pages : 408
  • ISBN 10 : 9780124171930

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Mucosal Health in Aquaculture Excerpt :

Mucosal Health in Aquaculture is an essential reference on mucosal health for the diverse aquaculture community. Rich in explanatory figures and schematics, the book includes important concepts such as structural and cellular composition of mucosal surfaces in fish and shellfish, known functional roles of molecular and cellular actors during pathogen invasion, impacts of nutrition on the mucosal barriers, impacts of chemical treatments on mucosal surfaces, mucosal vaccines and vaccination strategies, and more. The health of cultured aquaculture species is critical in establishing the sustainable growth of the aquaculture industry worldwide, and mucosal health is of particular interest to those working in aquaculture because mucosal surfaces (skin, gill, intestine, reproductive tissues) constitute the first line of defense against pathogen invasion. Mucosal Health in Aquaculture captures the latest research on mucosal barriers in aquaculture species and their impacts on nutrition and immunity to ensure sustainable aquaculture development. Includes research case studies to exhibit the importance of various integrated approaches to mucosal health Examines the latest scientific methods and technologies to maximize efficiencies for healthy fish production for farming Brings together the latest knowledge and research on mucosal barriers and mechanisms from world-wide experts in mucosal health Utilizes detailed diagrams and figures to enhance comprehension

Nanovaccines Book

Nanovaccines


  • Author : Sergio Rosales-Mendoza
  • Publisher : Springer Nature
  • Release Date : 2019-11-07
  • Genre: Technology & Engineering
  • Pages : 343
  • ISBN 10 : 9783030316686

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Nanovaccines Excerpt :

This book provides a compilation of the current developments in mucosal nanovaccines, which are an attractive approach to fight against infectious and non-communicable diseases. Since nanomaterials possess unique properties; many of them have a positive effect on vaccine efficacy when used as antigen carriers and have been applied in vaccinology with significant advances over the past years. This book addresses the methodologies for mucosal nanovaccines synthesis; based on the following nanomaterials: gold, PLGA, silica, and chitosan nanoparticles; as well as nanogels, carbon nanotubes, liposomes, and Virus-like particles. A description of the immunogenic properties of the mucosal nanovaccines is presented, highlighting the improvements achieved with this approach when compared to conventional formulations. Mucosal vaccines constitute the most practical immunization approach since they are easy to administer (promoting patient ́s comfort and increasing compliance), allow triggering relevant immune responses at both the site of administration and distant compartments, and thus may protect the main entry portal for pathogens (oral, nasal, and genital mucosae). In this context, the potential of nanovaccines to result in new mucosal formulations in the benefit of global health is analyzed. Covers the synthesis and functionalization of nanomaterials for the development of nanovaccines; Discusses the underlying mechanisms involved in the induction of immune responses through mucosal compartments and the advantages of nanomaterials in the formulation of nanovaccines; Transmits the state of the art for the development of mucosal nanovaccines; Provides routes for the design and evaluation of mucosal nanovaccines; Presents key perspectives for the field of mucosal vaccine development.

Principles of Mucosal Immunology Book

Principles of Mucosal Immunology


  • Author : Phillip D. Smith
  • Publisher : Garland Science
  • Release Date : 2020-04-21
  • Genre: Medical
  • Pages : 596
  • ISBN 10 : 9781000754490

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Principles of Mucosal Immunology Excerpt :

This respected graduate-level textbook provides comprehensive and accessible coverage of the basic and clinical aspects of the mucosal immune system, addressing the major components of the mucosal barrier ̶ gastrointestinal, upper and lower respiratory, ocular, and genitourinary mucosal immune systems ̶ in a highly user-friendly style. The editors of and contributors to the book, all internationally-recognized leaders, present the current principles, concepts, and basic processes involved in mucosal immunology, mucosal diseases, and host defense at mucosal surfaces. Topics discussed include the development and structure of the mucosal immune system and its cellular constituents, host-microbe relationships, infection, mucosal diseases, and vaccines. The second edition has been carefully updated throughout to reflect the latest developments from clinical research and key literature has been fully updated.

Immunopotentiators in Modern Vaccines Book

Immunopotentiators in Modern Vaccines


  • Author : Virgil Schijns
  • Publisher : Elsevier
  • Release Date : 2005-12-19
  • Genre: Medical
  • Pages : 384
  • ISBN 10 : 0080457215

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Immunopotentiators in Modern Vaccines Excerpt :

Immunopotentiators in Modern Vaccines provides an in-depth insight and overview of a number of most promising immunopotentiators in modern vaccines. In contrast to existing books on the subject it provides recent data on the critical mechanisms governing the activity of vaccine adjuvants and delivery systems. Knowledge of immunological pathways and scenarios of the cells and molecules involved is described and depicted in comprehensive illustrations. Contributions from leading international authorities in the field Well-illustrated, informative figures present the interactions between immunopotentiators and the host immune system Each chapter lists advantages and potential hurdles for achieving a practical application for the specific immunopentiator

Janeway s Immunobiology Book

Janeway s Immunobiology


  • Author : Kenneth Murphy
  • Publisher : Garland Science
  • Release Date : 2010-06-22
  • Genre: Medical
  • Pages : null
  • ISBN 10 : 0815344570

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Janeway s Immunobiology Excerpt :

The Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.

Mucosal Immunology Book

Mucosal Immunology


  • Author : Jiri Mestecky
  • Publisher : Academic Press
  • Release Date : 2015-03-06
  • Genre: Medical
  • Pages : 2540
  • ISBN 10 : 9780124159754

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Mucosal Immunology Excerpt :

Mucosal Immunology, now in its fourth edition, is the only comprehensive reference covering the basic science and clinical manifestations of mucosal immunology. Most infectious agents enter the body through the various mucous membranes, and many common infections take place in or on mucous membranes, making this subject an area of singular importance in the field of immunology. This book contains new research data, exceptional illustrations, original theory, a new perspective, and excellent organization. It covers immune system topics, such as inductive and effector tissues and cells, and development and physiology of the mucosal barrier; diseases in the digestive system, respiratory tract, and genitourinary tract; and immunodeficiency. The most comprehensive text on mucosal immunology from internationally recognized experts in the field Includes exceptional color illustrations, new research data, original theory and information on all mucosal diseases Contains nine new chapters and an expanded appendix

Canadian Immunization Guide Book

Canadian Immunization Guide


  • Author : Canada. National Advisory Committee on Immunization
  • Publisher : Unknown
  • Release Date : 2006
  • Genre: Immunization
  • Pages : 372
  • ISBN 10 : 0660193922

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Canadian Immunization Guide Excerpt :

The seventh edition of the Canadian Immunization Guide was developed by the National Advisory Committee on Immunization (NACI), with the support ofthe Immunization and Respiratory Infections Division, Public Health Agency of Canada, to provide updated information and recommendations on the use of vaccines in Canada. The Public Health Agency of Canada conducted a survey in 2004, which confi rmed that the Canadian Immunization Guide is a very useful and reliable resource of information on immunization.

Periparturient Diseases of Dairy Cows Book

Periparturient Diseases of Dairy Cows


  • Author : Burim N. Ametaj
  • Publisher : Springer
  • Release Date : 2017-12-21
  • Genre: Science
  • Pages : 276
  • ISBN 10 : 9783319430331

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Periparturient Diseases of Dairy Cows Excerpt :

This book summarizes the results achieved so far by application of various biological systems (including genomics, transcriptomics, proteomics, and metabolomics) involved in the pathomechanisms and early diagnosis of periparturient diseases as specific biomarkers of disease in cattle. These emerging technologies help to extensively enhance our understanding of the etiology and pathogenesis of periparturient diseases of transition dairy cows. The book includes a chapter dedicated to ‘omics’ sciences and one that discusses the myths established in animal and veterinary sciences in recent decades and emerging, new paradigms. The diseases discussed include metritis, mastitis, laminitis, ketosis, rumen acidosis, periparturient immunosuppression, gastrointestinal microbiota and their involvement in disease, infertility, fatty liver, milk fever, and retained placenta. This book is intended for academics, veterinarians, animal nutritionists, researchers, and graduate students working in the field of ‘omics sciences’ with a special interest in dairy cattle health.

Fish Vaccination Book

Fish Vaccination


  • Author : Roar Gudding
  • Publisher : John Wiley & Sons
  • Release Date : 2014-05-05
  • Genre: Technology & Engineering
  • Pages : 404
  • ISBN 10 : 9780470674550

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Fish Vaccination Excerpt :

Fish farming, in seawater and in freshwater, in cages, tanks or ponds, makes an ever-increasing and significant contribution to the production of aquatic food in many regions of the world. During the last few decades there has been significant progress and expansion in the aquaculture sector, characterized by intensified production and the exploitation of many new species. Aquaculture must be a sustainable bio-production, environmentally as well as economically. Disease prevention in order to reduce losses, and the use of antimicrobials is crucial in this perspective. Vaccination has, in a few years, become the most important method for disease prevention in aquaculture, and effective prophylaxis based on stimulation of the immune system of the fish is essential for further development of the industry. This book provides general information about disease prevention in fish by vaccination, as well as specific descriptions of the correct use of vaccines against the most important bacterial and viral infectious diseases of aquatic animals. The book is written by some of the world’s leading experts in the subject, drawn from many countries where aquaculture is a significant and expanding part of the economy. Fish Vaccination is an encyclopedia of fish vaccinology for every present and future aquaculturist. Professionals in the aquaculture sector, including fish veterinarians and fish biologists, within the industry, in scientific institutions and regulatory authorities will all find a huge wealth of commercially important knowledge within this book. Libraries in all universities where aquaculture, biological and veterinary sciences are studied and taught should have copies of this important book on their shelves.

Vaccinology Book

Vaccinology


  • Author : W. John W. Morrow
  • Publisher : John Wiley & Sons
  • Release Date : 2012-09-04
  • Genre: Medical
  • Pages : 552
  • ISBN 10 : 9781405185745

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Vaccinology Excerpt :

Covering all aspects of vaccine research and development in one volume, this authoritative resource takes a comprehensive and systematic approach to the science of vaccinology focusing not only on basic science, but also on the many stages required to commercialize and navigate the regulatory requirements for human application, both in the United States and Europe. Reviews in detail the process of designing a vaccine, from the initial stages of antigen discovery to human application Includes evaluation of vaccine efficacy and safety Details clinical trial design, including regulatory requirements Discusses the emerging field of active cellular immunotherapy Vaccinology: Principles and Practice provides an invaluable resource for clinicians, scientific and medical researchers, lecturers and postdoctoral fellows working in the field of vaccines.